Travel Information
Compare train, bus, and flight for St. Louis, MO to Boston, MA
Omio recommends booking the train as it is the most popular option from St. Louis, MO to Boston, MA among Omio's users. If you are prioritising price take the bus with prices starting from €77. For those with little time consider booking a flight which can get you there in 4h 24m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.5 - 1.5kg. The ticket price range depends on the travel mode: a bus costs an average of €77, and a train costs an average of €176.
Distance: 1035 miles (1667 km)
Compare train with
Most popular Train | Flight | Bus |
|---|---|---|
€482 Average price | €318 Average price | €135 Average price Cheapest |
27h 45m Average total duration 27h 15m Onboard + 30m Additional time* | 7h 24m Average total duration Fastest 4h 24m Onboard + 3h 0m Additional time* | 26h 41m Average total duration 26h 11m Onboard + 30m Additional time* |
0.5 - 1.5kg CO2 emissions Lowest | 5.0 - 10.0kg CO2 emissions | 1.7 - 4.2kg CO2 emissions |
![]() Most popular train company | ![]() Most popular airline | ![]() Most popular bus company |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom St. Louis, MO to Boston, MA
How to get from St. Louis, MO to Boston, MA by train, bus or flight.
Our recommendation
The best way to travel from St. Louis, MO to Boston, MA is by taking a train because it’s the best combination of price and speed.
318 Lincoln Service Missouri River Runner · 448 Lake Shore LimitedCheapest
318 Lincoln Service Missouri River Runner · 448 Lake Shore LimitedFastest
318 Lincoln Service Missouri River Runner · 448 Lake Shore LimitedOther options
318 Lincoln Service Missouri River Runner · 448 Lake Shore Limited
22 Texas Eagle · 448 Lake Shore Limited
22 Texas Eagle · 448 Lake Shore LimitedFind all the dates and times for this journey by train, bus, flight, and ferry .
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FAQs: Travel from St. Louis, MO to Boston, MA
Travel to Boston, MA easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from St. Louis, MO to Boston, MA.

There are 3 options to travel to Boston, MA from St. Louis, MO including taking a train, bus or flight.
The cheapest way to go to Boston, MA from St. Louis, MO is by taking a bus, which costs on average $50 (€45).
This is compared to other ways of getting from St. Louis, MO to Boston, MA:
Taking a bus costs $30 (€27) less than taking a flight, which costs on average $80 (€72) for the same trip.
A bus is $110 (€99) less than a train for this trip with tickets for a train from St. Louis, MO to Boston, MA costing on average $160 (€144).
The quickest way to travel from St. Louis, MO to Boston, MA is by flight, which takes on average 4 h 31 min compared to other travel options that take longer:
Bus takes on average 28 h 5 min.
Taking a train requires on average 35 h of travel time.
The distance from St. Louis, MO to Boston, MA is approximately 1033 miles (1666 km).
The average frequency per day from St. Louis, MO to Boston, MA is:
- 3 buses per day.
- 31 flights a day.
- 9 trains a day.
However, we recommend checking specific travel dates for your journey to Boston, MA from St. Louis, MO as scheduled services by train, bus or flight can vary by season or day of the week.
These are the most popular departure and arrival points from St. Louis, MO to Boston, MA:
Omio works with many trusted partners that can help you travel the best way from St. Louis, MO to Boston, MA:
- You can take a bus from St. Louis, MO to Boston, MA with Greyhound. Cheap tickets can be found for $50 (€45) with Greyhound from St. Louis, MO to Boston, MA.
- You can take a flight from St. Louis, MO to Boston, MA with American Airlines or Republic Airlines. Cheap tickets can be found for $136 (€123) with American Airlines from St. Louis, MO to Boston, MA.
- You can go to Boston, MA from St. Louis, MO by train with Amtrak. You'll see cheap train tickets for $160 (€144) with Amtrak from St. Louis, MO to Boston, MA on Omio.
Yes, there are direct services available from St. Louis, MO to Boston, MA with the following travel companies:
- Direct bus with.
- Direct services by plane with.
- Direct train with.
Direct services tend to save you time and add more convenience in getting you to Boston, MA as you won't need to transfer at another stop in between, so it's worth paying attention to before booking your tickets between St. Louis, MO and Boston, MA.
Travelling from St. Louis, MO to Boston, MA: related information
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