- Must visit
Saint Louis Art Museum
Vast art museum in Forest Park with global collections from antiquity to modern works and strong free general admission.
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Journey information
Overview: San Diego, CA to St. Louis, MO flight
USAUSA
Flights from San Diego, CA to St. Louis, MO depart on average 59 times per day, taking around 5h 30m. Cheap flight tickets for this journey start at €120 but you can travel from only €117 by bus.
The earliest flight runs at 05:00, the last at 23:58. The fastest flight covers the 1560 miles (2512 km) distance in 5h 21m. January is the cheapest month to fly.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from €117
Distance 1560 miles (2512 km) |
Average flight duration 5h 30m |
Cheapest ticket price €120 |
Flights per day 59 |
Fastest flight 5h 21m |
First flight 5:00 AM |
Last flight 11:58 PM |
Cheapest Month Jan |
Cheapest Day Thu |
High Season Apr - Jun |
Low Season Jul - Sep |
Best time to book 42 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from €117
The cheapest and fastest flights from San Diego, CA to St. Louis, MO
Showing times and prices for Aug 06
Cheapest price
€225
Average price
€225
Fastest journey
8 h 6 m
Average duration
8 h 18 m
Flights per day
2
Distance
2512 km
Cheap tickets
The best way to find a cheap flight ticket from San Diego, CA to St. Louis, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from San Diego, CA to St. Louis, MO will cost around €225 if you buy it on the day, but the cheapest tickets can be found for only €225.
Fast flights
Of the 2 flights that leave San Diego, CA for St. Louis, MO onThu, Aug 06, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Aug 06 the direct flights cover the 2512 km distance in an average of 8 h 18 m but if you time it right, some flights will get you there in just 8 h 6 m .
On Thu, Aug 06 the longest flights will take 8 h 29 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
4:00 PM8h29San Diego, CA12:29 AMSt. Louis, MO€2251One-way0 transfers- 2:15 PM8h06San Diego, CA10:21 PMSt. Louis, MO€2251One-way0 transfers
- 2:15 PM8h06San Diego, CA10:21 PMSt. Louis, MO€2251One-way0 transfers
- 4:00 PM8h29San Diego, CA12:29 AMSt. Louis, MO€2251One-way0 transfers
Travel Information
Compare train, bus, and flight for San Diego, CA to St. Louis, MO
Omio recommends booking the flight as it is the most popular option from San Diego, CA to St. Louis, MO among Omio's users. If you are prioritising price take the bus with prices starting from €117. For those with little time consider booking a flight which can get you there in 5h 30m. The ticket price range depends on the travel mode: a bus costs an average of €117, and a train costs an average of €176.
Distance: 1560 miles (2512 km)
Compare flight with
Most popular Flight | Train | Bus | Driving |
|---|---|---|---|
€205 Average price | €264 Average price | €203 Average price Cheapest | €310 Average price (fuel + tolls) |
8h 30m Average total duration Fastest 5h 30m Onboard + 3h 0m Additional time* | 48h 5m Average total duration 47h 35m Onboard + 30m Additional time* | 47h 40m Average total duration 47h 10m Onboard + 30m Additional time* | 26h 25m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
The cheapest way to travel from San Diego, CA to St. Louis, MO is a bus with an average price of €203.
This is compared to other travel options from San Diego, CA to St. Louis, MO:
A bus is €1 less than a flight for this route with tickets for a flight from San Diego, CA to St. Louis, MO costing on average €205.
A bus is €60 less than a train for this route with tickets for a train from San Diego, CA to St. Louis, MO costing on average €264.
The fastest way to travel from San Diego, CA to St. Louis, MO is by flight with an average journey time of 5h 30m.
Other travel options to St. Louis, MO take longer:
Bus takes on average 47h 10m.
Train takes on average 47h 35m.
It's helpful to compare your options as there are 3 ways to travel between San Diego, CA and St. Louis, MO including taking a train, bus, and flight.
We recommend using the flight as it is the most popular way to get from San Diego, CA to St. Louis, MO among Omio's users.
Live departures
San Diego, CA to St. Louis, MO flight times
The table below shows live departures for San Diego, CA to St. Louis, MO flights for today, Wednesday, August 5. You can also manually refresh the results below to see updated flight journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 1:20 PM San Diego, CA | 7h08 | 8:28 PM St. Louis, MO | 0 transfersDirect | |
| 10:46 PM San Diego, CA | 6h36 | 5:22 AM St. Louis, MO | 0 transfersDirect | |
This is the last flight of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets San Diego, CA to St. Louis, MO by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book San Diego, CA to St. Louis, MO flights with Omio?
American Airlines operates all flights services from San Diego, CA to St. Louis, MO.
Omio is an official ticket reseller for all your travel options from San Diego, CA to St. Louis, MO.
Why book with Omio vs American Airlines?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare American Airlines with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from San Diego, CA to St. Louis, MO.
Why book with Omio over Trip, Edreams or Skyscanner?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from San Diego, CA to St. Louis, MO.
Airlines: American Airlines from San Diego, CA to St. Louis, MOFind the best flights between San Diego, CA to St. Louis, MO with Omio's travel partners American Airlines from €117. We can find you the best deals, schedules and tickets when comparing and booking the best trip.
American Airlines
About
American Airlines is one of the largest airlines in the world, connecting travelers to hundreds of destinations across the United States, Latin America, Europe, Asia, and beyond. Operating from major hubs such as Dallas/Fort Worth, Miami, and Charlotte, American offers a wide range of travel options. Passengers can choose from Economy with affordable fares, Premium Economy with extra space, or Business and First Class featuring flat-bed seats, premium dining, and lounge access. With a modern fleet and membership in the oneworld alliance, American Airlines combines global reach with comfort and reliability.
Luggage & cancellation policy
Average Duration
5h 21m
Cheapest Price
€120
Luggage included
1 carry-on bag (22 x 14 x 9 inches) and 1 personal item (18 x 14 x 8 inches) included in most fares
Additional luggage
Checked bags fees vary by route. First checked bag typically $30, second $40 on domestic flights
Cancellation Policy
Basic Economy tickets cannot be changed or refunded. Other fares allow changes with fee, refunds subject to fare rules.
Pregnant on board
Passengers can fly up to 36 weeks for single pregnancies, 32 weeks for multiple pregnancies. Medical certificate required within 7 days of departure if within 4 weeks of due date.
Unaccompagned minor
Children ages 5-14 can travel alone using American Airlines Unaccompanied Minor Service. Service fee is $150 each way.
Amenities on board the airplane
Wifi
Food sold onboard
USB plugs
Accessibility
American Airlines provides wheelchair assistance and special services for passengers with disabilities. Assistance must be requested at least 48 hours before departure.
Pets
Small dogs and cats allowed in cabin for $125 fee. Must be in approved carrier under seat. Service animals allowed.
Entertaiment on board
Complete guide to St. Louis, MO
Things to do in St. Louis, MO
Discover the best of St. Louis, MO — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect St. Louis, MO trip today.
- Recommended
Missouri History Museum
Leading history museum covering St. Louis, Missouri, and national stories through rotating exhibitions in Forest Park.
- Recommended
Saint Louis Science Center
Interactive science museum with hands-on exhibits, planetarium, and family-friendly displays near Forest Park.
- Must visit
Gateway Arch National Park Grounds
Lively downtown riverfront district with trails, views of the Arch, public art, and access to major historic sites.
- Must visit
Forest Park
Large urban park with trails, lakes, zoo access, and major museums, ideal for walking between top attractions.
- Recommended
Tower Grove Park
Beloved neighborhood park with formal lily ponds, pavilions, and one of the city's most photographed landscapes.
- Vegetarian
St. Louis-Style Pizza
A thin, cracker-like crust pizza cut into squares and topped with Provel cheese, a St. Louis original loved for its distinct texture and tangy flavor.
- Vegetarian
Toasted Ravioli
Crisp, breaded ravioli said to be born on The Hill, usually served with marinara. It is a signature St. Louis Italian-American appetizer.
- Vegetarian
Gooey Butter Cake
Sticky butter cake with a dense base and gooey sweet top. A longtime St. Louis bakery favorite often enjoyed for breakfast or dessert.
Bulrush
Refined contemporary restaurant with tasting menus and strong national acclaim. Elegant fine dining focused on seasonal Midwestern ingredients.
Ted Drewes Frozen Custard
Beloved frozen custard stand serving concretes and sundaes since 1929. Casual, nostalgic, and one of the city's iconic dessert stops.
Pappy's Smokehouse
Popular smokehouse known for St. Louis barbecue, especially ribs, brisket, and pork steak, in a polished but relaxed atmosphere.
United States dollar ($)
Moderate for U.S. city breaks: hotels and dining are reasonable, transit is limited, and attractions often cost less than in larger U.S. tourist cities.
Average meal costs
- Budget
- $10-15 for fast food or casual lunch.
- Mid-range
- $20-35 per person for a mid-range restaurant meal.
- Fine dining
- $60+ per person at upscale restaurants.
- Coffee
- $3-5 for coffee or cappuccino.
Tipping culture
Tip 18-20% at restaurants, $1-2 per drink at bars, and 10-15% for taxis. Cafes often have tip jars or screen prompts.
FAQs: San Diego, CA to St. Louis, MO Flight
Find answers to the most common questions about traveling from San Diego, CA to St. Louis, MO by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.
Cheap plane tickets from San Diego, CA to St. Louis, MO can start from as little as €120 when you book in advance. The average flight ticket price for San Diego, CA to St. Louis, MO is €205 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by plane from San Diego, CA to St. Louis, MO is 5h 21m to travel the 1560 miles (2512 km) long route. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest flight from San Diego, CA to St. Louis, MO leaves at 5:00 AM. Plan your trip with the Journey Planner from Omio.
The latest flight from San Diego, CA to St. Louis, MO leaves at 11:58 PM.
There are 59 flights a day from San Diego, CA to St. Louis, MO which require at least one change with American Airlines. Schedules can vary on holidays or weekends with fewer flights.
When taking a flight from San Diego, CA to St. Louis, MO, you can count on American Airlines for the best way to get you to St. Louis, MO. You can also check all possible airlines who offer a service between San Diego, CA and St. Louis, MO and compare the amenities they offer before buying a plane ticket.
Flights from San Diego, CA to St. Louis, MO generally leave from San Diego International Airport and arrive in St. Louis Lambert International Airport.San Diego International Airport is 2 miles (4 km) away from San Diego, CA city centre and St. Louis Lambert International Airport is 1 miles (2 km) from St. Louis, MO city centre.
The cheapest month for a flight from San Diego, CA to St. Louis, MO is January.
It's helpful to compare your options as there are 3 ways to travel between San Diego, CA and St. Louis, MO including taking a train, bus, and flight.
Since neither San Diego, CA nor St. Louis, MO are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
There is a time difference of 2 h between San Diego, CA and St. Louis, MO all year round.
The best events to attend in St. Louis, MO include:
- St. Louis Mardi Gras, a vibrant celebration featuring parades, live music, and festive activities in the Soulard neighborhood
- St. Louis Art Fair, an annual event showcasing local and national artists with art exhibits, live performances, and culinary delights
- Fair St. Louis, a multi-day Independence Day festival with fireworks, concerts, and family-friendly activities along the Gateway Arch.
The best holidays to experience in St. Louis, MO include:
- Independence Day, vibrant fireworks and festive celebrations throughout the city
- Labor Day, pleasant weather and various outdoor activities
- Thanksgiving, a time for family gatherings with a charming autumn atmosphere.
The best season to visit St. Louis, MO is Spring or Fall. The best weather to explore St. Louis, MO is during April-May or September-October.
We recommend using the flight as it is the most popular way to get from San Diego, CA to St. Louis, MO among Omio's users.
For domestic flights we recommend to arrive 1.5 to 2 hours before departure. Please check the website of your departure airport if in doubt. Some airports may offer booking time slots for security checks or offer additional information on when to get there based on time of day.
Most airlines permit carry-on bags that fit within specific dimensions (e.g., 22 x 14 x 9 inches or 56 x 36 x 23 cm), including handles and wheels. Bags must fit in the overhead bin or under the seat in front of you.
Many airlines impose weight limits, commonly ranging between 7 kg (15 lbs) and 12 kg (26 lbs). Typically, passengers are allowed one carry-on bag and one personal item (for example a purse, laptop bag, or backpack). Personal items must fit under the seat in front of you. Budget Airlines (like Ryanair or Wizz Air) have stricter size and weight limits, often requiring fees for larger carry-ons. Full-Service Airlines have more lenient policies, sometimes including more spacious dimensions or higher weight limits depending on your ticket class.
The list of items prohibited on an airplane varies by country and airline, but in general, the following items are not allowed in carry-on or checked baggage: Weapons and self-defence items, sharp objects, flammable materials, explosives, toxic substances, or liquids over 100ml (except for medications and baby essentials). In checked baggage, firearms (without authorization), explosives, large lithium batteries, and hazardous chemicals are prohibited. Electronic cigarettes must be in carry-on bags, while alcohol and dry ice have restrictions. Always check with your airline for specific regulations.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In St. Louis, MO, travelers should be cautious in certain neighborhoods with higher crime rates, especially after dark. Common safety concerns include petty theft, pickpocketing, and occasional scams targeting visitors near popular attractions like the Gateway Arch. It’s advisable to stay in well-populated areas, avoid displaying valuables openly, and use reputable transportation services to minimize risks.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular airports
Popular airports from San Diego, CA to St. Louis, MO
Most San Diego, CA to St. Louis, MO flights use the San Diego International Airport to St. Louis Lambert International Airport airport pair. Use this guide to compare San Diego, CA and St. Louis, MO airports on this route, check city-centre transport, alongside checking practicalities like airport facilities and services.
Departure airports in San Diego
Arrival airports in St. Louis
Which San Diego, CA airport do flights to St. Louis, MO leave from?
Flights from San Diego, CA to St. Louis, MO depart from San Diego International Airport. The airport is 2 miles (4 km) from San Diego, CA city centre at 3225 N Harbor Dr, San Diego, CA 92101, USA.
San Diego International Airport (SAN)3225 N Harbor Dr, San Diego, CA 92101, USA
City-centre transport
Getting to San Diego International Airport from San Diego city centre
San Diego International Airport is 4 km from San Diego city centre. Public transport options include:
Bus923, 992 · 12m · €5 · every ~10 min
923, 992 · 13m · €5 · every ~10 min
San Diego International Airport airport facilities and services
San Diego International Airport has practical services for this route, including Wifi, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Shower, Lounge, Lost and Found Office, and Car Rental.
Food and drink
Food options include: Restaurants in terminals 1 and 2, including fast food and sit-down options like The Counter and Phil's BBQ
Wi-Fi and ATMs
Free Wi-Fi available throughout the airport. ATMs are located in all terminals.
Luggage and lost property
Lost and found is available at the station.
Parking, taxis and toilets
Available at San Diego International Airport: Parking, Taxis, WC.
Bike and car services
Available at San Diego International Airport: Car Rental.
Accessibility
Accessibility facilities are available at San Diego International Airport: Elevators, ramps.
Shops, hotels and contact
Nearby hotels include Hotels nearby, Sheraton San Diego Hotel & Mari within walking distance..
McClellan-Palomar Airport (CLD)2198 Palomar Airport Rd, Carlsbad, CA 92008, USA+1 760-431-4646
City-centre transport
Getting to McClellan-Palomar Airport from San Diego city centre
TrainPacific Surfliner · 2h 11m · €17 · every ~2 min
BusAmtrak Thruway Connecting Service · 2h 3m · €17
101 · 3h 3m · €23 · every ~4 min
McClellan-Palomar Airport airport facilities and services
McClellan-Palomar Airport has practical services for this route, including Accessibility.
Accessibility
Accessibility facilities are available at McClellan-Palomar Airport: The place has an entrance that is wheelchair-accessible.
Which St. Louis, MO airport do flights from San Diego, CA arrive at?
Flights from San Diego, CA to St. Louis, MO arrive at St. Louis Lambert International Airport. St. Louis Lambert International Airport is 1 miles (2 km) from St. Louis, MO city centre.
St. Louis Lambert International Airport (STL)10701 Lambert Intertiol Blvd, St. Louis, MO 63145, USA
City-centre transport
Getting to St. Louis Lambert International Airport from St. Louis city centre
St. Louis Lambert International Airport is 2 km from St. Louis city centre. Public transport options include:
TrainMlr · 31m · €3 · every ~7 min
BusGreyhound US1210 · 25m · €2
St. Louis Lambert International Airport airport facilities and services
St. Louis Lambert International Airport has practical services for this route, including Wifi, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Shower, Lounge, Lost and Found Office, and Car Rental.
Food and drink
Food options include: Restaurants in both terminals, including fast food and sit-down options like Starbucks and Chili's
Wi-Fi and ATMs
Free Wi-Fi available throughout the airport. ATMs are located in both terminals.
Luggage and lost property
Lost and found is available at the station.
Parking, taxis and toilets
Available at St. Louis Lambert International Airport: Parking, Taxis, WC.
Bike and car services
Available at St. Louis Lambert International Airport: Car Rental.
Accessibility
Accessibility facilities are available at St. Louis Lambert International Airport: Elevators, ramps.
Shops, hotels and contact
Nearby hotels include Hotels nearby, such as Marriott St. Louis Airport within walking distance..
More options for your journey from San Diego, CA to St. Louis, MO
Here are some other resources that might have the information you need
Most popular flights to and from St. Louis, MO and San Diego, CA
Most popular flights to St. Louis, MO
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