- Must visit
Pinacoteca di Brera
One of Italy’s leading art museums, known for masterpieces by Raphael, Caravaggio, and Mantegna in the elegant Brera district.
Cheapest price
$91
Average price
$119
Fastest journey
13 h 15 m
Average duration
13 h 44 m
Buses per day
43
Distance
646 km
The best way to find a cheap bus ticket from Prague to Milan is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Prague to Milan will cost around $119 if you buy it on the day, but the cheapest tickets can be found for only $91.
Of the 43 buses that leave Prague for Milan on Sat, May 30, 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, May 30 the direct buses cover the 646 km distance in an average of 13 h 44 m but if you time it right, some buses will get you there in just 13 h 15 m .
On Sat, May 30 the slowest buses will take 14 h 10 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus
FlixBus · FlixBusOmio recommends booking the flight as it is the most popular option from Prague to Milan among Omio's users. If you are prioritising price take the bus with prices starting from $58. For those with little time consider booking a flight which can get you there in 2h 38m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.6 - 1.6kg. The ticket price range depends on the travel mode: a bus costs an average of $58, and a flight costs an average of $34.
Distance: 401 miles (646 km)
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
$85 Average price Cheapest | $177 Average price | $134 Average price | $265 Average price (fuel + tolls) |
16h 25m Average total duration 15h 55m Onboard + 30m Additional time* | 5h 38m Average total duration Fastest 2h 38m Onboard + 3h 0m Additional time* | 14h 39m Average total duration 14h 9m Onboard + 30m Additional time* | 9h 2m Average total duration (door-to-door) |
0.6 - 1.6kg CO2 emissions Lowest | 1.9 - 3.9kg CO2 emissions | - CO2 emissions | - CO2 emissions |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Prague to Milan:
A bus is $48 (€39) less than a train for this route with tickets for a train from Prague to Milan costing on average $134 (€108).
A bus is $92 (€74) less than a flight for this route with tickets for a flight from Prague to Milan costing on average $177 (€143).
Other travel options to Milan take longer:
Train takes on average 14h 9m.
Bus takes on average 15h 55m.
Tickets start at around $85 (€69) compared to roughly $265 (€213) in fuel and tolls — a saving of about $179 (€144). The journey takes 15h 55m versus 9h 2m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by FlixBus, Infobus, Musil Tour.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 02:30AM | Arrival Time 09:00PM | Duration 18h30 | Departure days Mon, Tue, Wed, Thu, Sat, Sun | Cheapest price $75 |
Operator FlixBus | Departure Time 04:10AM | Arrival Time 11:05PM | Duration 18h55 | Departure days Mon, Thu | Cheapest price $72 |
Operator FlixBus | Departure Time 06:20AM | Arrival Time 12:15AM | Duration 17h55 | Departure days Sat, Sun | Cheapest price $113 |
Operator FlixBus | Departure Time 08:30AM | Arrival Time 02:50AM | Duration 18h20 | Departure days Sat | Cheapest price $113 |
Operator FlixBus | Departure Time 08:45AM | Arrival Time 11:05PM | Duration 14h20 | Departure days Mon, Tue, Wed, Thu | Cheapest price $78 |
Operator FlixBus | Departure Time 09:00AM | Arrival Time 12:05AM | Duration 15h05 | Departure days Mon, Tue, Wed, Thu, Sat, Sun | Cheapest price $78 |
Operator FlixBus | Departure Time 09:20AM | Arrival Time 02:15AM | Duration 16h55 | Departure days Mon, Tue, Wed, Thu | Cheapest price $78 |
Operator FlixBus | Departure Time 09:40AM | Arrival Time 12:05AM | Duration 14h25 | Departure days Mon, Tue, Wed, Thu, Sat, Sun | Cheapest price $78 |
Operator FlixBus | Departure Time 09:55AM | Arrival Time 12:05AM | Duration 14h10 | Departure days Sat, Sun | Cheapest price $103 |
Operator FlixBus | Departure Time 10:20AM | Arrival Time 12:05AM | Duration 13h45 | Departure days Sat, Sun | Cheapest price $84 |
Operator FlixBus | Departure Time 10:55AM | Arrival Time 02:50AM | Duration 15h55 | Departure days Mon, Sat, Sun | Cheapest price $100 |
Operator FlixBus | Departure Time 12:50PM | Arrival Time 06:30AM | Duration 17h40 | Departure days Mon, Tue, Wed, Thu, Sat, Sun | Cheapest price $89 |
Operator FlixBus | Departure Time 12:55PM | Arrival Time 06:30AM | Duration 17h35 | Departure days Sun | Cheapest price $116 |
Operator FlixBus | Departure Time 01:05PM | Arrival Time 02:50AM | Duration 13h45 | Departure days Mon, Thu, Sat | Cheapest price $93 |
Operator FlixBus | Departure Time 02:00PM | Arrival Time 02:50AM | Duration 12h50 | Departure days Sun | Cheapest price $112 |
Operator FlixBus | Departure Time 02:15PM | Arrival Time 02:50AM | Duration 12h35 | Departure days Sun | Cheapest price $112 |
Operator FlixBus | Departure Time 02:30PM | Arrival Time 06:30AM | Duration 16h00 | Departure days Mon, Tue, Wed, Thu, Sat, Sun | Cheapest price $105 |
Operator FlixBus | Departure Time 03:05PM | Arrival Time 06:30AM | Duration 15h25 | Departure days Mon, Tue, Wed, Thu, Sat | Cheapest price $103 |
Operator FlixBus | Departure Time 03:10PM | Arrival Time 06:30AM | Duration 15h20 | Departure days Mon, Thu, Sat, Sun | Cheapest price $104 |
Operator FlixBus | Departure Time 04:00PM | Arrival Time 10:25AM | Duration 18h25 | Departure days Wed, Thu, Fri, Sat | Cheapest price $80 |
Operator FlixBus | Departure Time 04:15PM | Arrival Time 10:25AM | Duration 18h10 | Departure days Wed, Thu, Fri, Sat, Sun | Cheapest price $80 |
Operator FlixBus | Departure Time 05:10PM | Arrival Time 09:10AM | Duration 16h00 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $74 |
Operator FlixBus | Departure Time 05:15PM | Arrival Time 10:15AM | Duration 17h00 | Departure days Everyday | Cheapest price $77 |
Operator FlixBus | Departure Time 05:30PM | Arrival Time 10:15AM | Duration 16h45 | Departure days Everyday | Cheapest price $85 |
Operator FlixBus | Departure Time 05:45PM | Arrival Time 09:00AM | Duration 15h15 | Departure days Everyday | Cheapest price $73 |
Operator FlixBus | Departure Time 06:05PM | Arrival Time 12:05PM | Duration 18h00 | Departure days Wed | Cheapest price $166 |
Operator FlixBus | Departure Time 06:20PM | Arrival Time 09:00AM | Duration 14h40 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $65 |
Operator FlixBus | Departure Time 06:30PM | Arrival Time 09:00AM | Duration 14h30 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $65 |
Operator FlixBus | Departure Time 06:55PM | Arrival Time 09:10AM | Duration 14h15 | Departure days Fri | Cheapest price $109 |
Operator FlixBus | Departure Time 07:25PM | Arrival Time 09:10AM | Duration 13h45 | Departure days Mon, Tue, Wed, Thu, Sat | Cheapest price $73 |
Operator FlixBus | Departure Time 07:30PM | Arrival Time 11:15AM | Duration 15h45 | Departure days Tue, Wed | Cheapest price $93 |
Operator FlixBus | Departure Time 08:10PM | Arrival Time 11:55AM | Duration 15h45 | Departure days Tue, Wed, Thu, Sat, Sun | Cheapest price $73 |
Operator FlixBus | Departure Time 08:20PM | Arrival Time 11:55AM | Duration 15h35 | Departure days Tue, Wed, Thu, Sat, Sun | Cheapest price $73 |
Operator FlixBus | Departure Time 08:25PM | Arrival Time 03:30PM | Duration 19h05 | Departure days Fri, Sun | Cheapest price $104 |
Operator FlixBus | Departure Time 09:25PM | Arrival Time 02:35PM | Duration 17h10 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price $86 |
Operator FlixBus | Departure Time 09:50PM | Arrival Time 02:45PM | Duration 16h55 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $73 |
Operator FlixBus | Departure Time 10:00PM | Arrival Time 03:30PM | Duration 17h30 | Departure days Tue, Wed | Cheapest price $104 |
Operator FlixBus | Departure Time 10:25PM | Arrival Time 02:45PM | Duration 16h20 | Departure days Everyday | Cheapest price $74 |
Operator RegioJet a.s. | Departure Time 11:00PM | Arrival Time 01:00PM | Duration 14h00 | Departure days Fri | Cheapest price $99 |
Operator FlixBus | Departure Time 11:05PM | Arrival Time 04:50PM | Duration 17h45 | Departure days Tue, Wed | Cheapest price $76 |
Operator FlixBus | Departure Time 11:40PM | Arrival Time 02:45PM | Duration 15h05 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $72 |
Operator FlixBus | Departure Time 11:45PM | Arrival Time 05:25PM | Duration 17h40 | Departure days Everyday | Cheapest price $72 |
Operator FlixBus | Departure Time 11:50PM | Arrival Time 02:45PM | Duration 14h55 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $73 |
The table below shows live departures for Prague to Milan buses for today, Friday, May 29. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus · FlixBus | 8:25 PM Praha, Zličín | 19h05 | 3:30 PM Milano, Autostazione Lampugnano | 2 transfers | |
FlixBus · FlixBus | 9:25 PM Praha, ÚAN Florenc | 17h10 | 2:35 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 1 transfer | |
FlixBus · FlixBus | 9:25 PM Praha, ÚAN Florenc | 15h25 | 12:50 PM Milano, Autostazione Lampugnano | 1 transfer | |
FlixBus · FlixBus · FlixBus | 9:50 PM Praha, Na Knížecí | 16h55 | 2:45 PM Milano, Autostazione Lampugnano | 2 transfers | |
FlixBus · FlixBus · FlixBus | 10:25 PM Praha, M. Horákové (Hradčanská) | 16h20 | 2:45 PM Milano, Autostazione Lampugnano | 2 transfers | |
(Prague -> Milan) | 11:00 PM Praha, ÚAN Florenc | 14h00 | 1:00 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus · FlixBus | 11:40 PM Praha, ÚAN Florenc | 15h05 | 2:45 PM Milano, Autostazione Lampugnano | 1 transfer | |
FlixBus · FlixBus | 11:45 PM Praha, ÚAN Florenc | 17h40 | 5:25 PM Milano, Autostazione Lampugnano | 1 transfer | |
FlixBus · FlixBus · FlixBus | 11:45 PM Praha, ÚAN Florenc | 21h10 | 8:55 PM Milano, Milan Linate Airport | 2 transfers | |
FlixBus · FlixBus | 11:50 PM Prague, Central Train Station | 14h55 | 2:45 PM Milano, Autostazione Lampugnano | 1 transfer | |
FlixBus · FlixBus · FlixBus | 2:30 AM Prague, Central Train Station | 18h30 | 9:00 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 2 transfers | |
FlixBus · FlixBus | 2:30 AM Prague, Central Train Station | 15h00 | 5:30 PM Milano, Autostazione Lampugnano | 1 transfer | |
FlixBus · FlixBus | 6:20 AM Praha, Černý Most | 17h55 | 12:15 AM Milano, Autostazione Lampugnano | 1 transfer | |
FlixBus · FlixBus · FlixBus | 8:30 AM Praha, Roztyly | 18h20 | 2:50 AM Milano, Autostazione Lampugnano | 2 transfers | |
FlixBus · FlixBus | 9:00 AM Prague, Central Train Station | 15h05 | 12:05 AM Milano, Autostazione Lampugnano | 1 transfer | |
FlixBus · FlixBus | 9:40 AM Praha, Na Knížecí | 14h25 | 12:05 AM Milano, Autostazione Lampugnano | 1 transfer | |
FlixBus · FlixBus | 9:55 AM Praha, Zličín | 14h10 | 12:05 AM Milano, Autostazione Lampugnano | 1 transfer | |
FlixBus | 10:20 AM Praha, ÚAN Florenc | 13h45 | 12:05 AM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus · FlixBus · FlixBus | 10:55 AM Praha, Na Knížecí | 15h55 | 2:50 AM Milano, Autostazione Lampugnano | 2 transfers | |
FlixBus · FlixBus · FlixBus | 12:50 PM Praha, M. Horákové (Hradčanská) | 17h40 | 6:30 AM Milano, Autostazione Lampugnano | 2 transfers | |
FlixBus · FlixBus · FlixBus | 12:50 PM Praha, M. Horákové (Hradčanská) | 21h25 | 10:15 AM Milano, Milan Linate Airport | 2 transfers | |
FlixBus · FlixBus | 1:05 PM Prague, Central Train Station | 13h45 | 2:50 AM Milano, Autostazione Lampugnano | 1 transfer | |
FlixBus · FlixBus | 2:30 PM Praha, Černý Most | 16h00 | 6:30 AM Milano, Autostazione Lampugnano | 1 transfer | |
FlixBus · FlixBus · FlixBus | 2:30 PM Praha, Černý Most | 19h45 | 10:15 AM Milano, Milan Linate Airport | 2 transfers | |
FlixBus · FlixBus · FlixBus | 3:05 PM Praha, Zličín | 15h25 | 6:30 AM Milano, Autostazione Lampugnano | 2 transfers | |
FlixBus · FlixBus | 3:10 PM Praha, ÚAN Florenc | 15h20 | 6:30 AM Milano, Autostazione Lampugnano | 1 transfer | |
FlixBus · FlixBus · FlixBus | 4:00 PM Praha, ÚAN Florenc | 18h25 | 10:25 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 4:15 PM Prague, Central Train Station | 18h10 | 10:25 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 2 transfers | |
FlixBus · FlixBus | 5:10 PM Praha, Roztyly | 16h00 | 9:10 AM Milano, Autostazione Lampugnano | 1 transfer | |
FlixBus · FlixBus · FlixBus | 5:15 PM Praha, ÚAN Florenc | 17h00 | 10:15 AM Milano, Milan Linate Airport | 2 transfers | |
FlixBus · FlixBus · FlixBus | 5:15 PM Praha, ÚAN Florenc | 17h15 | 10:30 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 2 transfers | |
FlixBus · FlixBus | 5:15 PM Praha, Na Knížecí | 13h15 | 6:30 AM Milano, Autostazione Lampugnano | 1 transfer | |
FlixBus · FlixBus · FlixBus | 5:30 PM Prague, Central Train Station | 16h45 | 10:15 AM Milano, Milan Linate Airport | 2 transfers | |
FlixBus · FlixBus · FlixBus | 5:30 PM Prague, Central Train Station | 17h00 | 10:30 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 2 transfers | |
FlixBus · FlixBus | 5:45 PM Praha, Na Knížecí | 15h15 | 9:00 AM Milano, Autostazione Lampugnano | 1 transfer | |
FlixBus · FlixBus · FlixBus | 5:45 PM Praha, Na Knížecí | 16h45 | 10:30 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 5:45 PM Praha, Na Knížecí | 16h30 | 10:15 AM Milano, Milan Linate Airport | 2 transfers | |
FlixBus | 6:20 PM Praha, ÚAN Florenc | 14h40 | 9:00 AM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus | 6:30 PM Prague, Central Train Station | 14h30 | 9:00 AM Milano, Autostazione Lampugnano | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Prague to Milan run on average 39 times per day, taking around 15h 55m. Cheap bus tickets for this journey start at $58 (€47) but you can travel from only $34 (€27) by flight.
There are 2 buses per day. The earliest bus runs at 00:15, the last at 23:55. The fastest bus covers the 401 miles (646 km) distance in 12h 50m.
Distance 401 miles (646 km) |
Average bus duration 15h 55m |
Cheapest ticket price $58 (€47) |
Buses per day 39 |
Direct buses 2 |
Fastest bus 12h 50m |
First bus 12:15 AM |
Last bus 11:55 PM |
Cheapest Month May |
Cheapest Day Tue |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Wed |
Least Busy Day Thu |
Best time to book 14 days |
Discover the best of Milan — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Milan trip today.
One of Italy’s leading art museums, known for masterpieces by Raphael, Caravaggio, and Mantegna in the elegant Brera district.
A major museum of 20th-century Italian art facing Piazza del Duomo, with strong Futurist holdings and striking city views.
A contemporary museum focused on world cultures and major temporary exhibitions, popular for its modern architecture and changing shows.
Milan’s canal district, best known for waterside walks, photogenic bridges, and lively atmosphere day and night.
A charming historic neighborhood of narrow streets, galleries, boutiques, and classic Milan character, ideal for wandering.
Milan’s main square and the symbolic heart of the city, surrounded by major landmarks and constant urban energy.
Creamy saffron risotto, one of Milan's signature dishes, prized for its rich flavor and golden color.
Braised veal shank cooked slowly until tender, traditionally served with gremolata and often paired with risotto.
Breaded veal cutlet fried in butter, a classic Milanese specialty and one of the city's most famous dishes.
Celebrated fine dining restaurant offering creative haute cuisine with an elegant, Michelin-starred reputation.
Famous central bakery known for panzerotti, a beloved casual stop near the Duomo with constant local appeal.
Modern Milanese restaurant known for refined Lombard classics in a stylish contemporary setting.
Milan is pricier than most Italian cities, especially for hotels, central dining, and aperitivo areas.
Service is often included or covered by coperto. Tipping is not required, but rounding up or leaving EUR 1-5 for good service is appreciated. Taxis can be rounded up.
Official public transport app
Milan Linate Airport, Milan -> Milano Centrale, Milan
Find answers to the most common questions about traveling from Prague to Milan by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Milan, this guide helps you travel smarter and with confidence.

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