- Must visit
Städel Museum
Frankfurt’s premier fine art museum with major European works from the Middle Ages to contemporary art. A top choice on the Museumsufer and one of the city’s cultural highlights.
Cheapest price
$49
Average price
$63
Fastest journey
6 h 25 m
Average duration
7 h 2 m
Buses per day
37
Distance
409 km
The best way to find a cheap bus ticket from Prague to Frankfurt am Main is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Prague to Frankfurt am Main will cost around $63 if you buy it on the day, but the cheapest tickets can be found for only $49.
Of the 37 buses that leave Prague for Frankfurt am Main on Sat, May 30, 15 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, May 30 the direct buses cover the 409 km distance in an average of 7 h 2 m but if you time it right, some buses will get you there in just 6 h 25 m .
On Sat, May 30 the slowest buses will take 7 h 20 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
(Prague -> Amsterdam)
FlixBus
FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
(Prague -> Amsterdam)
FlixBus
FlixBus
FlixBus · FlixBus
FlixBus · FlixBusOmio recommends booking the train as it is the most popular option from Prague to Frankfurt am Main among Omio's users. If you are prioritising price take the bus with prices starting from $31. For those with little time consider booking a flight which can get you there in 3h 26m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of $31, and a flight costs an average of $141.
Distance: 254 miles (409 km)
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$47 Average price Cheapest | $98 Average price | $255 Average price | $114 Average price (fuel + tolls) |
6h 58m Average total duration 6h 28m Onboard + 30m Additional time* | 6h 22m Average total duration 5h 52m Onboard + 30m Additional time* | 6h 26m Average total duration Fastest 3h 26m Onboard + 3h 0m Additional time* | 5h 1m Average total duration (door-to-door) |
0.4 - 1.0kg CO2 emissions | 0.1 - 0.4kg CO2 emissions Lowest | 1.2 - 2.5kg CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Prague to Frankfurt am Main:
A bus is $50 (€41) less than a train for this route with tickets for a train from Prague to Frankfurt am Main costing on average $98 (€79).
A bus is $207 (€167) less than a flight for this route with tickets for a flight from Prague to Frankfurt am Main costing on average $255 (€206).
Other travel options to Frankfurt am Main take longer:
Train takes on average 5h 52m.
Bus takes on average 6h 28m.
Tickets start at around $47 (€38) compared to roughly $114 (€92) in fuel and tolls — a saving of about $67 (€54). The journey takes 6h 28m versus 5h 1m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by FlixBus, BlaBlaCar Bus, Infobus, BlaBlaCar.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator BlaBlaCar | Departure Time 01:40AM | Arrival Time 06:40AM | Duration 5h00 | Departure days Thu | Cheapest price $24 |
Operator FlixBus | Departure Time 02:00AM | Arrival Time 12:00PM | Duration 10h00 | Departure days Mon, Fri, Sat, Sun | Cheapest price $47 |
Operator FlixBus | Departure Time 03:50AM | Arrival Time 11:20AM | Duration 7h30 | Departure days Everyday | Cheapest price $34 |
Operator FlixBus | Departure Time 04:10AM | Arrival Time 11:20AM | Duration 7h10 | Departure days Everyday | Cheapest price $34 |
Operator FlixBus | Departure Time 06:00AM | Arrival Time 04:00PM | Duration 10h00 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price $40 |
Operator FlixBus | Departure Time 06:40AM | Arrival Time 04:25PM | Duration 9h45 | Departure days Sat, Sun | Cheapest price $78 |
Operator FlixBus | Departure Time 07:55AM | Arrival Time 05:55PM | Duration 10h00 | Departure days Mon, Fri, Sun | Cheapest price $64 |
Operator FlixBus | Departure Time 08:30AM | Arrival Time 06:00PM | Duration 9h30 | Departure days Fri, Sun | Cheapest price $62 |
Operator FlixBus | Departure Time 08:50AM | Arrival Time 04:45PM | Duration 7h55 | Departure days Everyday | Cheapest price $34 |
Operator FlixBus | Departure Time 09:10AM | Arrival Time 04:45PM | Duration 7h35 | Departure days Everyday | Cheapest price $34 |
Operator FlixBus | Departure Time 09:55AM | Arrival Time 06:55PM | Duration 9h00 | Departure days Everyday | Cheapest price $39 |
Operator FlixBus | Departure Time 10:30AM | Arrival Time 07:25PM | Duration 8h55 | Departure days Everyday | Cheapest price $33 |
Operator FlixBus | Departure Time 10:55AM | Arrival Time 07:25PM | Duration 8h30 | Departure days Everyday | Cheapest price $33 |
Operator BlaBlaCar | Departure Time 12:00PM | Arrival Time 05:30PM | Duration 5h30 | Departure days Sun | Cheapest price $23 |
Operator FlixBus | Departure Time 12:30PM | Arrival Time 09:30PM | Duration 9h00 | Departure days Mon, Tue, Wed, Thu, Sat, Sun | Cheapest price $34 |
Operator BlaBlaCar | Departure Time 12:40PM | Arrival Time 05:30PM | Duration 4h50 | Departure days Sun | Cheapest price $25 |
Operator FlixBus | Departure Time 12:50PM | Arrival Time 09:30PM | Duration 8h40 | Departure days Mon, Tue, Wed, Thu, Sat, Sun | Cheapest price $34 |
Operator FlixBus | Departure Time 02:30PM | Arrival Time 11:50PM | Duration 9h20 | Departure days Mon, Tue, Wed, Thu, Sat, Sun | Cheapest price $38 |
Operator FlixBus | Departure Time 02:45PM | Arrival Time 12:20AM | Duration 9h35 | Departure days Everyday | Cheapest price $38 |
Operator BlaBlaCar | Departure Time 03:30PM | Arrival Time 08:40PM | Duration 5h10 | Departure days Sun | Cheapest price $31 |
Operator FlixBus | Departure Time 04:15PM | Arrival Time 12:20AM | Duration 8h05 | Departure days Everyday | Cheapest price $34 |
Operator FlixBus | Departure Time 05:15PM | Arrival Time 01:10AM | Duration 7h55 | Departure days Mon, Thu, Fri | Cheapest price $45 |
Operator FlixBus | Departure Time 05:45PM | Arrival Time 02:50AM | Duration 9h05 | Departure days Everyday | Cheapest price $38 |
Operator FlixBus | Departure Time 06:30PM | Arrival Time 02:50AM | Duration 8h20 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $45 |
Operator FlixBus | Departure Time 07:30PM | Arrival Time 03:15AM | Duration 7h45 | Departure days Everyday | Cheapest price $38 |
Operator FlixBus | Departure Time 08:00PM | Arrival Time 05:10AM | Duration 9h10 | Departure days Everyday | Cheapest price $38 |
Operator FlixBus | Departure Time 08:40PM | Arrival Time 04:00AM | Duration 7h20 | Departure days Mon, Tue, Wed, Thu, Sat, Sun | Cheapest price $38 |
Operator FlixBus | Departure Time 09:50PM | Arrival Time 06:30AM | Duration 8h40 | Departure days Everyday | Cheapest price $38 |
Operator FlixBus | Departure Time 10:25PM | Arrival Time 08:15AM | Duration 9h50 | Departure days Everyday | Cheapest price $38 |
Operator RegioJet a.s. | Departure Time 11:00PM | Arrival Time 05:25AM | Duration 6h25 | Departure days Everyday | Cheapest price $37 |
Operator FlixBus | Departure Time 11:05PM | Arrival Time 06:00AM | Duration 6h55 | Departure days Everyday | Cheapest price $36 |
Operator FlixBus | Departure Time 11:50PM | Arrival Time 09:20AM | Duration 9h30 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $45 |
The table below shows live departures for Prague to Frankfurt am Main buses for today, Friday, May 29. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 7:30 PM Praha, ÚAN Florenc | 7h20 | 2:50 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 1 transfer | |
FlixBus · FlixBus | 7:30 PM Praha, ÚAN Florenc | 7h45 | 3:15 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 1 transfer | |
FlixBus · FlixBus | 8:00 PM Praha, ÚAN Florenc | 9h35 | 5:35 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 1 transfer | |
FlixBus · FlixBus | 8:00 PM Praha, ÚAN Florenc | 9h10 | 5:10 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 1 transfer | |
FlixBus · FlixBus | 9:50 PM Praha, Na Knížecí | 8h10 | 6:00 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 1 transfer | |
FlixBus · FlixBus | 9:50 PM Praha, Na Knížecí | 8h40 | 6:30 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 1 transfer | |
FlixBus · FlixBus | 10:25 PM Praha, M. Horákové (Hradčanská) | 7h35 | 6:00 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 1 transfer | |
FlixBus · FlixBus | 10:25 PM Praha, M. Horákové (Hradčanská) | 8h05 | 6:30 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 1 transfer | |
(Prague -> Amsterdam) | 11:00 PM Praha, ÚAN Florenc | 6h25 | 5:25 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 0 transfersDirect | |
FlixBus | 11:05 PM Praha, ÚAN Florenc | 6h55 | 6:00 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 0 transfersDirect | |
FlixBus | 11:05 PM Praha, ÚAN Florenc | 7h25 | 6:30 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 0 transfersDirect | |
FlixBus · FlixBus | 11:50 PM Prague, Central Train Station | 9h30 | 9:20 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 1 transfer | |
| Saturday, May 30 | |||||
FlixBus+ FlixTrain | 2:00 AM Prague, Central Train Station | 10h00 | 12:00 PM Frankfurt South station | 1 transfer | |
FlixBus | 3:50 AM Prague, Central Train Station | 7h30 | 11:20 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 0 transfersDirect | |
FlixBus | 4:10 AM Praha, Na Knížecí | 7h10 | 11:20 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 0 transfersDirect | |
FlixBus · FlixBus | 6:40 AM Praha, ÚAN Florenc | 9h45 | 4:25 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 1 transfer | |
FlixBus | 8:50 AM Praha, ÚAN Florenc | 7h55 | 4:45 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 0 transfersDirect | |
FlixBus | 9:10 AM Praha, Na Knížecí | 7h35 | 4:45 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 0 transfersDirect | |
FlixBus · FlixBus | 9:55 AM Praha, Zličín | 9h00 | 6:55 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 1 transfer | |
FlixBus · FlixBus | 9:55 AM Praha, Zličín | 9h30 | 7:25 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 1 transfer | |
FlixBus | 10:30 AM Praha, ÚAN Florenc | 8h25 | 6:55 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 0 transfersDirect | |
FlixBus | 10:30 AM Praha, ÚAN Florenc | 8h55 | 7:25 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 0 transfersDirect | |
FlixBus | 10:55 AM Praha, Na Knížecí | 8h30 | 7:25 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 0 transfersDirect | |
FlixBus | 10:55 AM Praha, Na Knížecí | 8h00 | 6:55 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 0 transfersDirect | |
FlixBus | 12:30 PM Praha, ÚAN Florenc | 9h00 | 9:30 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 0 transfersDirect | |
FlixBus | 12:50 PM Praha, M. Horákové (Hradčanská) | 8h40 | 9:30 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 0 transfersDirect | |
FlixBus · FlixBus | 2:30 PM Praha, Černý Most | 9h20 | 11:50 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 1 transfer | |
FlixBus · FlixBus | 2:30 PM Praha, Černý Most | 9h50 | 12:20 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 1 transfer | |
FlixBus · FlixBus | 2:45 PM Prague, Central Train Station | 9h35 | 12:20 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 1 transfer | |
FlixBus | 4:15 PM Praha, ÚAN Florenc | 7h35 | 11:50 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 0 transfersDirect | |
FlixBus | 4:15 PM Praha, ÚAN Florenc | 8h05 | 12:20 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 0 transfersDirect | |
FlixBus · FlixBus | 5:45 PM Praha, Na Knížecí | 7h50 | 1:35 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 1 transfer | |
FlixBus · FlixBus | 5:45 PM Praha, Na Knížecí | 7h25 | 1:10 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 1 transfer | |
FlixBus · FlixBus | 6:30 PM Prague, Central Train Station | 8h45 | 3:15 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 1 transfer | |
FlixBus · FlixBus | 6:30 PM Prague, Central Train Station | 8h20 | 2:50 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 1 transfer | |
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Prague to Frankfurt am Main run on average 30 times per day, taking around 6h 28m. Cheap bus tickets for this journey start at $31 (€25) if you book in advance.
There are 14 buses per day. The earliest bus runs at 00:05, the last at 23:55. The fastest bus covers the 254 miles (409 km) distance in 6h 25m.
Distance 254 miles (409 km) |
Average bus duration 6h 28m |
Cheapest ticket price $31 (€25) |
Buses per day 30 |
Direct buses 14 |
Fastest bus 6h 25m |
First bus 12:05 AM |
Last bus 11:55 PM |
Cheapest Month Apr |
Cheapest Day Wed |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Wed |
Least Busy Day Sat |
Best time to book 91 days |
Discover the best of Frankfurt am Main — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Frankfurt am Main trip today.
Frankfurt’s premier fine art museum with major European works from the Middle Ages to contemporary art. A top choice on the Museumsufer and one of the city’s cultural highlights.
One of Germany’s most famous natural history museums, especially popular for its dinosaur skeletons and family-friendly science displays.
Leading contemporary art museum known for its bold architecture and strong postwar and modern collections. Ideal for visitors interested in cutting-edge exhibitions.
Frankfurt’s historic central square, lined with reconstructed timber-frame houses and key civic landmarks. Essential for first-time visitors.
Rebuilt old town quarter between Römerberg and the cathedral, blending historic character with modern reconstruction. Very popular for photos and strolling.
Riverside museum district on both banks of the Main, ideal for walking, architecture, and cultural stops. One of Frankfurt’s signature urban areas.
Thin smoked pork sausages with protected regional status, traditionally gently heated and served with bread, mustard, and potato salad.
Frankfurt’s famous cold herb sauce made with seven herbs, usually mixed with sour cream or yogurt and served with eggs or boiled potatoes.
A tangy sour milk cheese marinated with onions, vinegar, and oil. A classic apple wine tavern snack strongly associated with Hesse.
Upscale dining venue with skyline views, refined modern cuisine, and a special-occasion atmosphere in one of Frankfurt’s landmark towers.
Classic Sachsenhausen apple wine tavern known for Grüne Soße, schnitzel, and other Frankfurt staples in a lively traditional setting.
Well-known historic Ebbelwoi restaurant serving hearty Hessian dishes such as Handkäs, ribs, and apple wine in a rustic atmosphere.
Prices are high by German standards, especially for hotels and dining in central areas, but supermarkets and transit stay reasonable.
Service is usually included. Round up in cafes and taxis; tip about 5-10% in restaurants for good service, usually by telling the total when paying.
Official public transport app
Flughafen Frankfurt Terminal 1 Busparkplatz P36, Frankfurt am Main -> Frankfurt (Main) Hauptbahnhof, Frankfurt am Main
Buses in Europe are an affordable way to travel between cities, with a number of companies offering both domestic and international routes. Buses from Prague to Frankfurt are operated by Polskibus, Flixbus, Postbus and Infobus, with numerous departures a day, between around 11:00 a.m. and about 10:30 p.m. The direct journey takes approximately 6.5 hours, with buses departing seven days a week. Flixbus also has two night departures with longer journey times, which require making a connection.
Buses from Prague to Frankfurt am Main depart from Florenc Bus Station located to the East of Prague city centre. The bus station is within easy walking distance of Prague's main attractions, as well as being on two Metro lines and frequent bus routes. Prague has an extensive public transport network of buses, trains, metro, water ferries and a funicular. Only electric powered public vehicles are permitted within the historic heart of Prague. A taxi rank is also located at Prague Florenc Bus Station.
Frankfurt am Main is the largest city in the state of Hesse. Frankfurt am Main combines charming 19th century streets with a modern, even futuristic, skyline. The older parts of the city contain elegant architecture, interesting streets and tranquil parks. Popular attractions in Frankfurt are the Archaeological Museum, the Museum of World Culture and the Goethe's House Museum. Buses from Prague to Frankfurt am Main arrive at Frankfurt's main train station. Frankfurt's transport network consists of U-Bahn trains, trams and buses in the city centre and S-Bahn trains serving the suburbs and surrounding towns. The bus network includes a regular night bus service, while taxis are also available at the train station.
Find answers to the most common questions about traveling from Prague to Frankfurt am Main by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Frankfurt am Main, this guide helps you travel smarter and with confidence.

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