- Must visit
Städel Museum
Major German art museum with masterpieces from Old Masters to modernism; a cornerstone stop on Frankfurt’s Museum Embankment.
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Cheapest price
$29
Average price
$55
Fastest journey
4h 40m
Average duration
8h 11m
Buses per day
37
Distance
248 km
Omio recommends booking the train as it is the most popular option from Prague to Frankfurt am Main among Omio's users. If you are prioritising price take the bus with prices starting from $30. For those with little time consider booking a flight which can get you there in 3h 26m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of $30, and a flight costs an average of $138.
Distance: 254 miles (409 km)
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$46 Average price Cheapest | $96 Average price | $249 Average price | $111 Average price (fuel + tolls) |
6h 58m Average total duration 6h 28m Onboard + 30m Additional time* | 6h 22m Average total duration 5h 52m Onboard + 30m Additional time* | 6h 26m Average total duration Fastest 3h 26m Onboard + 3h 0m Additional time* | 5h 1m Average total duration (door-to-door) |
0.4 - 1.0kg CO2 emissions | 0.1 - 0.4kg CO2 emissions Lowest | 1.2 - 2.5kg CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Prague to Frankfurt am Main:
A bus is $49 (€41) less than a train for this route with tickets for a train from Prague to Frankfurt am Main costing on average $96 (€79).
A bus is $203 (€167) less than a flight for this route with tickets for a flight from Prague to Frankfurt am Main costing on average $249 (€206).
Other travel options to Frankfurt am Main take longer:
Train takes on average 5h 52m.
Bus takes on average 6h 28m.
Tickets start at around $46 (€38) compared to roughly $111 (€92) in fuel and tolls — a saving of about $65 (€54). The journey takes 6h 28m versus 5h 1m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by FlixBus, BlaBlaCar Bus, Infobus, BlaBlaCar.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 02:00AM | Arrival Time 12:00PM | Duration 10h00 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $82 |
Operator FlixBus | Departure Time 03:25AM | Arrival Time 11:00AM | Duration 7h35 | Departure days Everyday | Cheapest price $48 |
Operator FlixBus | Departure Time 03:40AM | Arrival Time 11:00AM | Duration 7h20 | Departure days Everyday | Cheapest price $48 |
Operator Infobus | Departure Time 04:30AM | Arrival Time 12:35PM | Duration 8h05 | Departure days Sat | Cheapest price $42 |
Operator FlixBus | Departure Time 06:00AM | Arrival Time 04:00PM | Duration 10h00 | Departure days Everyday | Cheapest price $51 |
Operator FlixBus | Departure Time 07:55AM | Arrival Time 05:55PM | Duration 10h00 | Departure days Mon, Thu, Fri, Sun | Cheapest price $48 |
Operator BlaBlaCar | Departure Time 08:20AM | Arrival Time 01:20PM | Duration 5h00 | Departure days Sun | Cheapest price $37 |
Operator FlixBus | Departure Time 08:30AM | Arrival Time 06:00PM | Duration 9h30 | Departure days Fri, Sun | Cheapest price $70 |
Operator FlixBus | Departure Time 08:50AM | Arrival Time 04:45PM | Duration 7h55 | Departure days Everyday | Cheapest price $44 |
Operator FlixBus | Departure Time 09:10AM | Arrival Time 04:45PM | Duration 7h35 | Departure days Everyday | Cheapest price $44 |
Operator FlixBus | Departure Time 09:55AM | Arrival Time 06:55PM | Duration 9h00 | Departure days Everyday | Cheapest price $45 |
Operator BlaBlaCar | Departure Time 10:00AM | Arrival Time 02:50PM | Duration 4h50 | Departure days Thu | Cheapest price $36 |
Operator BlaBlaCar | Departure Time 10:20AM | Arrival Time 03:10PM | Duration 4h50 | Departure days Tue | Cheapest price $39 |
Operator FlixBus | Departure Time 10:30AM | Arrival Time 06:55PM | Duration 8h25 | Departure days Everyday | Cheapest price $44 |
Operator FlixBus | Departure Time 10:55AM | Arrival Time 06:55PM | Duration 8h00 | Departure days Everyday | Cheapest price $44 |
Operator FlixBus | Departure Time 12:30PM | Arrival Time 09:30PM | Duration 9h00 | Departure days Everyday | Cheapest price $45 |
Operator FlixBus | Departure Time 12:50PM | Arrival Time 09:30PM | Duration 8h40 | Departure days Everyday | Cheapest price $45 |
Operator BlaBlaCar | Departure Time 02:00PM | Arrival Time 07:20PM | Duration 5h20 | Departure days Tue | Cheapest price $29 |
Operator FlixBus | Departure Time 02:30PM | Arrival Time 12:20AM | Duration 9h50 | Departure days Mon, Tue, Wed, Thu, Sat, Sun | Cheapest price $51 |
Operator BlaBlaCar | Departure Time 02:30PM | Arrival Time 07:50PM | Duration 5h20 | Departure days Sun | Cheapest price $44 |
Operator FlixBus | Departure Time 02:45PM | Arrival Time 12:20AM | Duration 9h35 | Departure days Everyday | Cheapest price $46 |
Operator BlaBlaCar | Departure Time 02:50PM | Arrival Time 07:30PM | Duration 4h40 | Departure days Sun | Cheapest price $44 |
Operator BlaBlaCar | Departure Time 04:00PM | Arrival Time 09:20PM | Duration 5h20 | Departure days Tue | Cheapest price $41 |
Operator BlaBlaCar | Departure Time 04:10PM | Arrival Time 08:50PM | Duration 4h40 | Departure days Wed | Cheapest price $44 |
Operator FlixBus | Departure Time 04:15PM | Arrival Time 12:20AM | Duration 8h05 | Departure days Everyday | Cheapest price $42 |
Operator BlaBlaCar | Departure Time 04:30PM | Arrival Time 09:10PM | Duration 4h40 | Departure days Tue | Cheapest price $41 |
Operator FlixBus | Departure Time 05:15PM | Arrival Time 01:35AM | Duration 8h20 | Departure days Mon, Thu, Fri | Cheapest price $45 |
Operator FlixBus | Departure Time 05:45PM | Arrival Time 03:15AM | Duration 9h30 | Departure days Everyday | Cheapest price $45 |
Operator FlixBus | Departure Time 06:30PM | Arrival Time 03:15AM | Duration 8h45 | Departure days Everyday | Cheapest price $45 |
Operator FlixBus | Departure Time 07:30PM | Arrival Time 02:50AM | Duration 7h20 | Departure days Everyday | Cheapest price $45 |
Operator FlixBus | Departure Time 08:00PM | Arrival Time 05:35AM | Duration 9h35 | Departure days Everyday | Cheapest price $45 |
Operator FlixBus | Departure Time 08:40PM | Arrival Time 05:30AM | Duration 8h50 | Departure days Everyday | Cheapest price $48 |
Operator FlixBus | Departure Time 09:50PM | Arrival Time 06:30AM | Duration 8h40 | Departure days Everyday | Cheapest price $45 |
Operator FlixBus | Departure Time 10:25PM | Arrival Time 06:30AM | Duration 8h05 | Departure days Everyday | Cheapest price $45 |
Operator RegioJet a.s. | Departure Time 11:00PM | Arrival Time 05:25AM | Duration 6h25 | Departure days Everyday | Cheapest price $42 |
Operator FlixBus | Departure Time 11:05PM | Arrival Time 06:00AM | Duration 6h55 | Departure days Everyday | Cheapest price $44 |
Operator FlixBus | Departure Time 11:50PM | Arrival Time 09:20AM | Duration 9h30 | Departure days Everyday | Cheapest price $42 |
The table below shows live departures for Prague to Frankfurt am Main buses for today, Tuesday, July 14. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus+ FlixTrain | 6:00 AM Praha, ÚAN Florenc | 10h00 | 4:00 PM Frankfurt South station | 1 transfer | |
FlixBus | 8:50 AM Praha, ÚAN Florenc | 7h55 | 4:45 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 0 transfersDirect | |
FlixBus | 9:10 AM Praha, Na Knížecí | 7h35 | 4:45 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 0 transfersDirect | |
FlixBus · FlixBus | 9:55 AM Praha, Zličín | 9h00 | 6:55 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 1 transfer | |
FlixBus · FlixBus | 9:55 AM Praha, Zličín | 9h30 | 7:25 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 1 transfer | |
FlixBus | 10:30 AM Praha, ÚAN Florenc | 8h55 | 7:25 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 0 transfersDirect | |
FlixBus | 10:30 AM Praha, ÚAN Florenc | 8h25 | 6:55 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 0 transfersDirect | |
FlixBus | 10:55 AM Praha, Na Knížecí | 8h30 | 7:25 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 0 transfersDirect | |
FlixBus | 10:55 AM Praha, Na Knížecí | 8h00 | 6:55 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 0 transfersDirect | |
FlixBus | 12:30 PM Praha, ÚAN Florenc | 9h00 | 9:30 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 0 transfersDirect | |
FlixBus | 12:50 PM Praha, M. Horákové (Hradčanská) | 8h40 | 9:30 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 0 transfersDirect | |
FlixBus · FlixBus | 2:30 PM Praha, Černý Most | 9h20 | 11:50 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 1 transfer | |
FlixBus · FlixBus | 2:30 PM Praha, Černý Most | 9h50 | 12:20 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 1 transfer | |
FlixBus · FlixBus | 2:45 PM Prague, Central Train Station | 9h35 | 12:20 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 1 transfer | |
FlixBus | 4:15 PM Praha, ÚAN Florenc | 7h35 | 11:50 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 0 transfersDirect | |
FlixBus | 4:15 PM Praha, ÚAN Florenc | 8h05 | 12:20 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 0 transfersDirect | |
FlixBus · FlixBus | 5:45 PM Praha, Na Knížecí | 9h05 | 2:50 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 1 transfer | |
FlixBus · FlixBus | 5:45 PM Praha, Na Knížecí | 9h30 | 3:15 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 1 transfer | |
FlixBus · FlixBus | 6:30 PM Prague, Central Train Station | 8h45 | 3:15 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 1 transfer | |
FlixBus · FlixBus | 6:30 PM Prague, Central Train Station | 8h20 | 2:50 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 1 transfer | |
FlixBus · FlixBus | 7:30 PM Praha, ÚAN Florenc | 7h20 | 2:50 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 1 transfer | |
FlixBus · FlixBus | 7:30 PM Praha, ÚAN Florenc | 7h45 | 3:15 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 1 transfer | |
FlixBus · FlixBus | 8:00 PM Praha, ÚAN Florenc | 9h35 | 5:35 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 1 transfer | |
FlixBus · FlixBus | 8:00 PM Praha, ÚAN Florenc | 9h10 | 5:10 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 1 transfer | |
FlixBus · FlixBus | 8:40 PM Praha, Na Knížecí | 7h20 | 4:00 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 1 transfer | |
FlixBus · FlixBus | 8:40 PM Praha, Na Knížecí | 8h50 | 5:30 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 1 transfer | |
FlixBus · FlixBus | 9:50 PM Praha, Na Knížecí | 8h10 | 6:00 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 1 transfer | |
FlixBus · FlixBus | 9:50 PM Praha, Na Knížecí | 8h40 | 6:30 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 1 transfer | |
FlixBus · FlixBus | 10:25 PM Praha, M. Horákové (Hradčanská) | 9h50 | 8:15 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 1 transfer | |
(Prague -> Amsterdam) | 11:00 PM Praha, ÚAN Florenc | 6h25 | 5:25 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 0 transfersDirect | |
FlixBus | 11:05 PM Praha, ÚAN Florenc | 7h25 | 6:30 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 0 transfersDirect | |
FlixBus | 11:05 PM Praha, ÚAN Florenc | 6h55 | 6:00 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 0 transfersDirect | |
FlixBus · FlixBus | 11:50 PM Prague, Central Train Station | 9h30 | 9:20 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 1 transfer | |
| Wednesday, July 15 | |||||
FlixBus | 3:25 AM Prague, Central Train Station | 7h35 | 11:00 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 0 transfersDirect | |
FlixBus | 3:40 AM Praha, Na Knížecí | 7h20 | 11:00 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 0 transfersDirect | |
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Prague to Frankfurt am Main run on average 30 times per day, taking around 6h 28m. Cheap bus tickets for this journey start at $30 (€25) if you book in advance.
There are 14 buses per day. The earliest bus runs at 00:05, the last at 23:55. The fastest bus covers the 254 miles (409 km) distance in 6h 25m.
Distance 254 miles (409 km) |
Average bus duration 6h 28m |
Cheapest ticket price $30 (€25) |
Buses per day 30 |
Direct buses 14 |
Fastest bus 6h 25m |
First bus 12:05 AM |
Last bus 11:55 PM |
Cheapest Month Apr |
Cheapest Day Wed |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Wed |
Least Busy Day Sat |
Best time to book 91 days |
Discover the best of Frankfurt am Main — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Frankfurt am Main trip today.
Major German art museum with masterpieces from Old Masters to modernism; a cornerstone stop on Frankfurt’s Museum Embankment.
Museum in Goethe’s birthplace presenting the writer’s life, era, and manuscripts; essential for literary and cultural history fans.
Large natural history museum with dinosaur skeletons, biodiversity displays, and strong geology exhibits; excellent for all ages.
Rebuilt old town quarter between Römer and cathedral, blending historic layouts with new architecture; ideal for strolling and photos.
Frankfurt’s riverside museum district and promenade, perfect for walking, major museums, and skyline views across the Main.
Large inner-city palm garden with themed greenhouses and landscaped grounds; a relaxing break from museums and shopping.
Green sauce made with seven fresh herbs, usually served with boiled eggs and potatoes. It is a Frankfurt classic with protected regional status.
Pork sausage lightly smoked and traditionally served hot with potato salad, sauerkraut, or bread. It is one of Frankfurt’s signature sausages.
Pressed and cured pork sausage, often sliced and served cold with bread, mustard, and pickles. It is a staple in Frankfurt cider taverns.
Two Michelin-starred dining with creative modern cuisine, extensive wine pairings, and a formal fine dining experience.
Refined restaurant in the old opera house area, known for modern European cuisine, polished service, and an elegant dining room.
Historic apple wine tavern in Sachsenhausen known for Apfelwein, green sauce, and classic Frankfurt dishes in a lively traditional setting.
Moderate for Germany: hotels can be pricey during trade fairs, but dining and public transport are reasonable for most tourists.
Round up or tip about 5-10% in restaurants for good service. Taxis are usually rounded up. Small change is common for cafes.
Official public transport app
Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) -> Frankfurt (Main) Hauptbahnhof
Buses in Europe are an affordable way to travel between cities, with a number of companies offering both domestic and international routes. Buses from Prague to Frankfurt are operated by Polskibus, Flixbus, Postbus and Infobus, with numerous departures a day, between around 11:00 a.m. and about 10:30 p.m. The direct journey takes approximately 6.5 hours, with buses departing seven days a week. Flixbus also has two night departures with longer journey times, which require making a connection.
Buses from Prague to Frankfurt am Main depart from Florenc Bus Station located to the East of Prague city centre. The bus station is within easy walking distance of Prague's main attractions, as well as being on two Metro lines and frequent bus routes. Prague has an extensive public transport network of buses, trains, metro, water ferries and a funicular. Only electric powered public vehicles are permitted within the historic heart of Prague. A taxi rank is also located at Prague Florenc Bus Station.
Frankfurt am Main is the largest city in the state of Hesse. Frankfurt am Main combines charming 19th century streets with a modern, even futuristic, skyline. The older parts of the city contain elegant architecture, interesting streets and tranquil parks. Popular attractions in Frankfurt are the Archaeological Museum, the Museum of World Culture and the Goethe's House Museum. Buses from Prague to Frankfurt am Main arrive at Frankfurt's main train station. Frankfurt's transport network consists of U-Bahn trains, trams and buses in the city centre and S-Bahn trains serving the suburbs and surrounding towns. The bus network includes a regular night bus service, while taxis are also available at the train station.
Find answers to the most common questions about traveling from Prague to Frankfurt am Main by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Frankfurt am Main, this guide helps you travel smarter and with confidence.

Most Prague to Frankfurt am Main buses use the Praha, ÚAN Florenc to Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) station pair, with some services arriving at Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36). Use this guide to compare Prague and Frankfurt am Main bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Praha, ÚAN Florenc is 1 km from Prague city centre. Public transport options include:
Praha, ÚAN Florenc has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Florenc (in the station), Bistro Florenc (0.2 km), Restaurace U Rozvařilů (0.5 km).
Free Wi-Fi. ATMs are located inside the station, offering multiple currency options.
Ticket office support is available at Praha, ÚAN Florenc.
Available at Praha, ÚAN Florenc: Parking, Taxis, WC.
Accessibility facilities are available at Praha, ÚAN Florenc: Elevators, ramps.
Praha, Na Knížecí is 2 km from Prague city centre. Public transport options include:
Praha, Na Knížecí has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, and WC.
Food options include: Café Na Knížecí (in the station), Bistro Praha (0.2 km), Restaurace U Knížete (0.5 km).
Free Wi-Fi. ATMs are located near the entrance.
Available at Praha, Na Knížecí: Parking, Taxis, WC.
Accessibility facilities are available at Praha, Na Knížecí: Elevators, ramps.
Praha, Hlavní Nádraží is 1 km from Prague city centre. Public transport options include:
Praha, Hlavní Nádraží has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Czech Bistro (in the station), Fast Food Express (in the station), Bohemian Café (0.2 km).
Free Wi-Fi. ATMs are located near the main entrance and ticketing area.
Ticket office support is available at Praha, Hlavní Nádraží.
Available at Praha, Hlavní Nádraží: Parking, Taxis, WC.
Accessibility facilities are available at Praha, Hlavní Nádraží: Elevators, ramps.
Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) is 10 km from Frankfurt am Main city centre. Public transport options include:
Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: McDonald's (in the station), Hausmann's (in the station).
Free Wi-Fi. ATMs are located throughout the terminal, offering various banking services.
Ticket office support is available at Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36).
Available at Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36): Parking, Taxis, WC.
Accessibility facilities are available at Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36): Elevators, ramps, assistance.
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