The cheapest and fastest buses from Prague to Frankfurt am Main
Cheapest price
$49
Average price
$74
Fastest journey
6 h 25 m
Average duration
6 h 57 m
Buses per day
34
Distance
409 km
The best way to find a cheap bus ticket from Prague to Frankfurt am Main is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Prague to Frankfurt am Main will cost around $74 if you buy it on the day, but the cheapest tickets can be found for only $49.
Of the 34 buses that leave Prague for Frankfurt am Main on Sun, Mar 01, 16 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Mar 01 the direct buses cover the 409 km distance in an average of 6 h 57 m but if you time it right, some buses will get you there in just 6 h 25 m .
On Sun, Mar 01 the slowest buses will take 7 h 20 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus
FlixBus
(Prague -> Amsterdam)
(Prague -> Amsterdam)
FlixBus
(Prague -> Amsterdam)
(Prague -> Amsterdam)
FlixBus
FlixBus
FlixBus · FlixBusTravel Information
Compare train, bus, and flight for Prague to Frankfurt am Main
Omio recommends booking the train as it is the most popular option from Prague to Frankfurt am Main among Omio's users. If you are prioritising price take the bus with prices starting from $29. For those with little time consider booking a flight which can get you there in 2h 33m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of $29, and a flight costs an average of $137.
Distance: 254 miles (409 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
$48 Average price Cheapest | $103 Average price | $198 Average price |
7h 46m Average total duration 7h 16m Onboard + 30m Additional time* | 6h 46m Average total duration 6h 16m Onboard + 30m Additional time* | 5h 33m Average total duration Fastest 2h 33m Onboard + 3h 0m Additional time* |
0.4 - 1.0kg CO2 emissions | 0.1 - 0.4kg CO2 emissions Lowest | 1.2 - 2.5kg CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Prague to Frankfurt am Main Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 02:00AM | Arrival Time 12:00PM | Duration 10h00 | Departure days Fri | Cheapest price $75 |
Operator FlixBus | Departure Time 03:30AM | Arrival Time 02:55PM | Duration 11h25 | Departure days Mon, Tue, Wed | Cheapest price $48 |
Operator FlixBus | Departure Time 03:50AM | Arrival Time 11:20AM | Duration 7h30 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $42 |
Operator FlixBus | Departure Time 04:10AM | Arrival Time 11:20AM | Duration 7h10 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $42 |
Operator FlixBus | Departure Time 05:50AM | Arrival Time 04:00PM | Duration 10h10 | Departure days Mon | Cheapest price $95 |
Operator FlixBus | Departure Time 06:00AM | Arrival Time 04:00PM | Duration 10h00 | Departure days Mon, Thu, Fri | Cheapest price $72 |
Operator FlixBus | Departure Time 06:40AM | Arrival Time 04:25PM | Duration 9h45 | Departure days Sat, Sun | Cheapest price $60 |
Operator FlixBus | Departure Time 07:35AM | Arrival Time 05:30PM | Duration 9h55 | Departure days Tue, Sun | Cheapest price $48 |
Operator FlixBus | Departure Time 07:55AM | Arrival Time 05:30PM | Duration 9h35 | Departure days Tue, Fri, Sun | Cheapest price $48 |
Operator FlixBus | Departure Time 08:50AM | Arrival Time 04:45PM | Duration 7h55 | Departure days Mon, Fri, Sat, Sun | Cheapest price $42 |
Operator FlixBus | Departure Time 09:10AM | Arrival Time 04:45PM | Duration 7h35 | Departure days Mon, Fri, Sat, Sun | Cheapest price $42 |
Operator FlixBus | Departure Time 09:55AM | Arrival Time 06:55PM | Duration 9h00 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $42 |
Operator FlixBus | Departure Time 10:30AM | Arrival Time 06:55PM | Duration 8h25 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $35 |
Operator FlixBus | Departure Time 10:55AM | Arrival Time 06:55PM | Duration 8h00 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $35 |
Operator FlixBus | Departure Time 12:30PM | Arrival Time 09:30PM | Duration 9h00 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $40 |
Operator FlixBus | Departure Time 12:50PM | Arrival Time 09:30PM | Duration 8h40 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $40 |
Operator FlixBus | Departure Time 02:30PM | Arrival Time 12:20AM | Duration 9h50 | Departure days Wed, Sat, Sun | Cheapest price $45 |
Operator FlixBus | Departure Time 02:45PM | Arrival Time 11:59PM | Duration 9h14 | Departure days Sat, Sun | Cheapest price $60 |
Operator BlaBlaCar | Departure Time 03:00PM | Arrival Time 08:20PM | Duration 5h20 | Departure days Sat | Cheapest price $38 |
Operator FlixBus | Departure Time 04:15PM | Arrival Time 11:50PM | Duration 7h35 | Departure days Everyday | Cheapest price $36 |
Operator FlixBus | Departure Time 05:30PM | Arrival Time 04:00AM | Duration 10h30 | Departure days Tue, Wed | Cheapest price $41 |
Operator FlixBus | Departure Time 05:45PM | Arrival Time 02:25AM | Duration 8h40 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $47 |
Operator FlixBus | Departure Time 06:45PM | Arrival Time 05:35AM | Duration 10h50 | Departure days Mon, Tue, Wed | Cheapest price $41 |
Operator FlixBus | Departure Time 07:30PM | Arrival Time 04:00AM | Duration 8h30 | Departure days Thu, Fri, Sat, Sun | Cheapest price $47 |
Operator FlixBus | Departure Time 08:00PM | Arrival Time 05:10AM | Duration 9h10 | Departure days Sat, Sun | Cheapest price $50 |
Operator FlixBus | Departure Time 08:15PM | Arrival Time 04:00AM | Duration 7h45 | Departure days Mon, Tue, Wed | Cheapest price $41 |
Operator FlixBus | Departure Time 08:40PM | Arrival Time 04:00AM | Duration 7h20 | Departure days Everyday | Cheapest price $41 |
Operator FlixBus | Departure Time 09:50PM | Arrival Time 06:00AM | Duration 8h10 | Departure days Wed, Thu, Fri, Sat, Sun | Cheapest price $41 |
Operator BlaBlaCar | Departure Time 10:00PM | Arrival Time 03:00AM | Duration 5h00 | Departure days Sat | Cheapest price $32 |
Operator FlixBus | Departure Time 10:25PM | Arrival Time 08:15AM | Duration 9h50 | Departure days Thu, Fri, Sat, Sun | Cheapest price $47 |
Operator Regiojet | Departure Time 11:00PM | Arrival Time 05:25AM | Duration 6h25 | Departure days Everyday | Cheapest price $36 |
Operator FlixBus | Departure Time 11:05PM | Arrival Time 06:00AM | Duration 6h55 | Departure days Thu, Fri, Sat, Sun | Cheapest price $42 |
Live departures
Prague to Frankfurt am Main bus times
The table below shows live departures for Prague to Frankfurt am Main buses for today, Saturday, February 28. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 5:40 AM Praha, ÚAN Florenc | 9h45 | 3:25 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 1 transfer | |
FlixBus | 7:50 AM Praha, ÚAN Florenc | 7h55 | 3:45 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 0 transfersDirect | |
FlixBus | 8:10 AM Praha, Na Knížecí | 7h35 | 3:45 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 0 transfersDirect | |
FlixBus · FlixBus | 8:55 AM Praha, Zličín | 9h00 | 5:55 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 1 transfer | |
FlixBus · FlixBus | 8:55 AM Praha, Zličín | 9h30 | 6:25 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 1 transfer | |
FlixBus | 9:30 AM Praha, ÚAN Florenc | 8h55 | 6:25 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 0 transfersDirect | |
FlixBus | 9:30 AM Praha, ÚAN Florenc | 8h25 | 5:55 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 0 transfersDirect | |
FlixBus | 9:55 AM Praha, Na Knížecí | 8h00 | 5:55 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 0 transfersDirect | |
FlixBus | 9:55 AM Praha, Na Knížecí | 8h30 | 6:25 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 0 transfersDirect | |
FlixBus | 11:30 AM Praha, ÚAN Florenc | 9h00 | 8:30 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 0 transfersDirect | |
FlixBus | 11:50 AM Praha, M. Horákové (Hradčanská) | 8h40 | 8:30 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 0 transfersDirect | |
FlixBus · FlixBus | 1:30 PM Praha, Černý Most | 9h50 | 11:20 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 1 transfer | |
FlixBus · FlixBus | 1:30 PM Praha, Černý Most | 9h20 | 10:50 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 1 transfer | |
FlixBus · FlixBus | 1:45 PM Prague, Central Train Station | 9h14 | 10:59 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 1 transfer | |
FlixBus | 3:15 PM Praha, ÚAN Florenc | 7h35 | 10:50 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 0 transfersDirect | |
FlixBus | 3:15 PM Praha, ÚAN Florenc | 8h05 | 11:20 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 0 transfersDirect | |
FlixBus · FlixBus | 4:45 PM Praha, Na Knížecí | 8h40 | 1:25 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 1 transfer | |
FlixBus · FlixBus | 4:45 PM Praha, Na Knížecí | 8h15 | 1:00 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 1 transfer | |
FlixBus · FlixBus | 6:30 PM Praha, ÚAN Florenc | 8h30 | 3:00 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 1 transfer | |
FlixBus · FlixBus | 7:00 PM Praha, ÚAN Florenc | 9h35 | 4:35 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 1 transfer | |
FlixBus · FlixBus | 7:00 PM Praha, ÚAN Florenc | 9h10 | 4:10 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 1 transfer | |
FlixBus · FlixBus | 7:40 PM Praha, Na Knížecí | 7h20 | 3:00 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 1 transfer | |
FlixBus · FlixBus | 7:40 PM Praha, Na Knížecí | 8h50 | 4:30 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 1 transfer | |
FlixBus · FlixBus | 8:50 PM Praha, Na Knížecí | 8h40 | 5:30 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 1 transfer | |
FlixBus · FlixBus | 8:50 PM Praha, Na Knížecí | 8h10 | 5:00 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 1 transfer | |
FlixBus · FlixBus | 9:25 PM Praha, M. Horákové (Hradčanská) | 9h50 | 7:15 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 1 transfer | |
(Prague -> Amsterdam) | 10:00 PM Praha, ÚAN Florenc | 6h25 | 4:25 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 0 transfersDirect | |
(Prague -> Amsterdam) | 10:00 PM Praha, ÚAN Florenc | 6h55 | 4:55 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 0 transfersDirect | |
FlixBus | 10:05 PM Praha, ÚAN Florenc | 7h25 | 5:30 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 0 transfersDirect | |
FlixBus | 10:05 PM Praha, ÚAN Florenc | 6h55 | 5:00 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 0 transfersDirect | |
FlixBus | 2:50 AM Prague, Central Train Station | 7h30 | 10:20 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 0 transfersDirect | |
FlixBus | 3:10 AM Praha, Na Knížecí | 7h10 | 10:20 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Prague to Frankfurt am Main by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Feb 28
Mar 01
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Mar 06
Mar 07
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Mar 11
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Mar 19
Mar 20
Why should you book Prague to Frankfurt am Main buses with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of BlaBlaCar Bus or Infobus to find the best option for your trip from Prague to Frankfurt am Main.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Prague to Frankfurt am Main.
Why book with Omio over Wanderu, Trainline or Checkmybus?
- Compare with other providers: On Omio, you can also compare tickets for the likes of BlaBlaCar Bus or Infobus to find the best option for your trip from Prague to Frankfurt am Main.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Prague to Frankfurt am Main.
Journey information
Overview: Bus from Prague to Frankfurt am Main
Buses from Prague to Frankfurt am Main run on average 30 times per day, taking around 7h 16m. Cheap bus tickets for this journey start at $29 (€23) if you book in advance.
There are 14 buses per day. The earliest bus runs at 00:05, the last at 23:55. The fastest bus covers the 254 miles (409 km) distance in 6h 25m.
Distance 254 miles (409 km) |
Average bus duration 7h 16m |
Cheapest ticket price $29 (€23) |
Buses per day 30 |
Direct buses 14 |
Fastest bus 6h 25m |
First bus 00:05 |
Last bus 23:55 |
Bus providers: FlixBus, BlaBlaCar Bus, Infobus, BlaBlaCar from Prague to Frankfurt am MainYou can travel by bus between Prague to Frankfurt am Main with FlixBus, BlaBlaCar Bus, Infobus, BlaBlaCar for as low as $29 (€23). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Infobus
BlaBlaCar Bus
BlaBlaCar
Buses from Prague to Frankfurt: Journey Details
Buses in Europe are an affordable way to travel between cities, with a number of companies offering both domestic and international routes. Buses from Prague to Frankfurt are operated by Polskibus, Flixbus, Postbus and Infobus, with numerous departures a day, between around 11:00 a.m. and about 10:30 p.m. The direct journey takes approximately 6.5 hours, with buses departing seven days a week. Flixbus also has two night departures with longer journey times, which require making a connection.
Taking the Bus from Prague
Buses from Prague to Frankfurt am Main depart from Florenc Bus Station located to the East of Prague city centre. The bus station is within easy walking distance of Prague's main attractions, as well as being on two Metro lines and frequent bus routes. Prague has an extensive public transport network of buses, trains, metro, water ferries and a funicular. Only electric powered public vehicles are permitted within the historic heart of Prague. A taxi rank is also located at Prague Florenc Bus Station.
Getting into Frankfurt am Main by Bus
Frankfurt am Main is the largest city in the state of Hesse. Frankfurt am Main combines charming 19th century streets with a modern, even futuristic, skyline. The older parts of the city contain elegant architecture, interesting streets and tranquil parks. Popular attractions in Frankfurt are the Archaeological Museum, the Museum of World Culture and the Goethe's House Museum. Buses from Prague to Frankfurt am Main arrive at Frankfurt's main train station. Frankfurt's transport network consists of U-Bahn trains, trams and buses in the city centre and S-Bahn trains serving the suburbs and surrounding towns. The bus network includes a regular night bus service, while taxis are also available at the train station.
FAQs: Bus from Prague to Frankfurt am Main
Find answers to the most common questions about traveling from Prague to Frankfurt am Main by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Frankfurt am Main, this guide helps you travel smarter and with confidence.

- Infobus
- Assistance
- Priority seating
- Transport for wheelchairs and mobility aids.
- BlaBlaCar Bus
- Assistance
- Priority boarding
- Accessible seating options.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Römer, a historic city hall with medieval architecture located in the heart of Frankfurt's old town
- Städel Museum, an art museum featuring a vast collection of European artworks from the Middle Ages to the present
- Palmengarten, a large botanical garden showcasing diverse plant species in themed greenhouses and outdoor areas
- Goethe House, the birthplace of the famous writer Johann Wolfgang von Goethe, now a museum dedicated to his life and works
- Frankfurt Cathedral, a Gothic-style church with a rich history and stunning architecture.
- Main Tower, a skyscraper with an observation deck providing panoramic views of the city
- Explore the vibrant Kleinmarkthalle, an indoor market offering a variety of local and international foods
- Visit the Senckenberg Natural History Museum, home to an extensive collection of dinosaur fossils and natural exhibits
- Take a leisurely walk along the River Main and enjoy the scenic views
- Experience the lively atmosphere of the Zeil, Frankfurt's premier shopping street.
- Infobus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Cancellations within 24 hours may incur a fee.
- BlaBlaCar Bus
- You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Infobus
- One carry-on bag up to 5kg (40x20x25) and one checked bag up to 20kg (50x30x80).
- BlaBlaCar Bus
- One carry-on bag up to 7kg and one checked bag up to 20kg.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Infobus
- 10€ per additional bag.
- BlaBlaCar Bus
- Additional luggage can be purchased for a fee.
- FlixBus
- Additional luggage can be purchased for a fee.
- Infobus
- Small pets allowed in carriers
- larger pets may require a separate ticket.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Prague to Frankfurt am Main
- 06:00-23:00
- Free Wi-Fi
- Cafeteria Florenc (in the station)
- Bistro Florenc (0.2 km)
- Restaurace U Rozvařilů (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 133, 135, 175, 207 Metro: B, C
- Free Wi-Fi
- Café Na Knížecí (in the station)
- Bistro Praha (0.2 km)
- Restaurace U Knížete (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 137, 176, 191 Metro: B
- 00:00-23:59
- Free Wi-Fi
- Czech Bistro (in the station)
- Fast Food Express (in the station)
- Bohemian Café (0.2 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 135, 175, 207 Metro: C Train: All major s
- 00:00-23:59
- Free Wi-Fi
- McDonald's (in the station)
- Hausmann's (in the station).
- Available outside the terminal at designated taxi stands.
- Elevators, ramps, assistance
- Available in the station.
- Bus: 61, 62, 77 Train: S8, S9
More options for your journey from Prague to Frankfurt am Main
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