4.9
4.6The cheapest and fastest buses from Iowa City, IA to St. Louis, MO
Cheapest price
$37
Average price
$37
Fastest journey
5 h 5 m
Average duration
5 h 5 m
Buses per day
1
Distance
356 km
The best way to find a cheap bus ticket from Iowa City, IA to St. Louis, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Iowa City, IA to St. Louis, MO will cost around $37 if you buy it on the day, but the cheapest tickets can be found for only $37.
Of the 1 buses that leave Iowa City, IA for St. Louis, MO on Fri, May 29, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, May 29 the direct buses cover the 356 km distance in an average of 5 h 5 m but if you time it right, some buses will get you there in just 5 h 5 m .
On Fri, May 29 the slowest buses will take 5 h 5 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
12:30 AM5h05Iowa City, IA5:35 AMSt. Louis, MO$371One-way0 transfers
- 12:30 AM5h05Iowa City, IA5:35 AMSt. Louis, MO$371One-way0 transfers
Travel Information
Compare bus and flight for Iowa City, IA to St. Louis, MO
Omio recommends booking the bus as it is the most popular option from Iowa City, IA to St. Louis, MO among Omio's users. If you are prioritising price take the bus with prices starting from $37. For those with little time consider booking a flight which can get you there in 4h 59m. The ticket price range depends on the travel mode: a bus costs an average of $37, and a flight costs an average of $279.
Distance: 221 miles (356 km)
Compare bus with
Most popular Bus | Flight | Driving |
|---|---|---|
$59 Average price Cheapest | $356 Average price | $54 Average price (fuel + tolls) |
5h 35m Average total duration 5h 5m Onboard + 30m Additional time* | 7h 59m Average total duration Fastest 4h 59m Onboard + 3h 0m Additional time* | 4h 0m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Iowa City, IA to St. Louis, MO:
A bus is $297 (€240) less than a flight for this route with tickets for a flight from Iowa City, IA to St. Louis, MO costing on average $356 (€288).
Other travel options to St. Louis, MO take longer:
Bus takes on average 5h 5m.
You'll arrive about -2h -5m sooner (5h 5m by bus vs 4h 0m by car) and save roughly $-5.52 (€-4.46) compared to fuel and tolls ($59 (€48) vs $54 (€44)). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by Greyhound.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Iowa City, IA to St. Louis, MO Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:30AM | Arrival Time 05:35AM | Duration 5h05 | Departure days Everyday | Cheapest price $37 |
Operator FlixBus | Departure Time 05:40PM | Arrival Time 12:25PM | Duration 18h45 | Departure days Fri | Cheapest price $180 |
Operator FlixBus | Departure Time 08:45PM | Arrival Time 12:25PM | Duration 15h40 | Departure days Fri | Cheapest price $108 |
Live departures
Iowa City, IA to St. Louis, MO bus times
The table below shows live departures for Iowa City, IA to St. Louis, MO buses for tomorrow, Thursday, May 28. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 12:30 AM Iowa City, IA | 5h05 | 5:35 AM St. Louis, MO | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Iowa City, IA to St. Louis, MO by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
May 28
May 29
May 30
May 31
Jun 01
Jun 02
Jun 03
Why should you book Iowa City, IA to St. Louis, MO buses with Omio?
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Iowa City, IA to St. Louis, MO.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Iowa City, IA to St. Louis, MO.
Journey information
Overview: Bus from Iowa City, IA to St. Louis, MO
USAUSA
Buses from Iowa City, IA to St. Louis, MO run on average 2 times per day, taking around 5h 5m. Cheap bus tickets for this journey start at $37 (€30) if you book in advance.
The earliest bus runs at 07:50, the last at 23:30. The fastest bus covers the 221 miles (356 km) distance in 5h 5m.
Distance 221 miles (356 km) |
Average bus duration 5h 5m |
Cheapest ticket price $37 (€30) |
Buses per day 2 |
Fastest bus 5h 5m |
First bus 7:50 AM |
Last bus 11:30 PM |
Cheapest Month Apr |
Cheapest Day Mon |
High Season Apr - Jun |
Low Season Jul - Sep |
Busiest Day Thu |
Least Busy Day Thu |
Bus providers: Greyhound from Iowa City, IA to St. Louis, MOYou can travel by bus between Iowa City, IA to St. Louis, MO with Greyhound for as low as $37 (€30). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from Iowa City, IA to St. Louis, MO
Find answers to the most common questions about traveling from Iowa City, IA to St. Louis, MO by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Iowa City, IA to St. Louis, MO
Most popular bus connections from Iowa City, IA
More options for your journey from Iowa City, IA to St. Louis, MO
Here are some other resources that might have the information you need
Most popular buses to and from St. Louis, MO and Iowa City, IA
Most popular bus connections to St. Louis, MO
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