Iowa City, IA to St. Louis, MO bus with Greyhound

Sat, Aug 29
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The cheapest and fastest buses from Iowa City, IA to St. Louis, MO

Showing times, prices and bookable tickets for Aug 30

Cheapest price on Aug 30

kr365

Average ticket price on Aug 30

kr365

Fastest journey on Aug 30

5 h 5 m

Average journey duration on Aug 30

5 h 5 m

Buses on Aug 30

1

Distance

356 km

Cheap tickets

The best way to find a cheap bus ticket from Iowa City, IA to St. Louis, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Iowa City, IA to St. Louis, MO will cost around kr365 if you buy it on the day, but the cheapest tickets can be found for only kr365.

Fast buses

On Sun, Aug 30, we found 1 buses from Iowa City, IA to St. Louis, MO, including 1 direct services.

On Sun, Aug 30 the direct buses cover the 356 km distance in an average of 5 h 5 m but if you time it right, some buses will get you there in just 5 h 5 m .

On Sun, Aug 30 the slowest buses will take 5 h 5 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

  • Greyhound
    12:30 AM5h05
    Iowa City, IA
    5:35 AMSt. Louis, MO
    kr3651One-way
    0 transfers

Travel Information

Compare bus and flight for Iowa City, IA to St. Louis, MO

Omio recommends booking the bus as it is the most popular option from Iowa City, IA to St. Louis, MO among Omio's users. If you are prioritising price, take the bus, with an average ticket price of kr540 For those with little time, consider booking a flight, which has an average total journey time of 5h 17m. Average ticket prices depend on the travel mode: a bus costs an average of kr540, while a flight costs an average of kr4441.

Distance: 221 miles (356 km)

Compare bus with

Most popular
Bus
Flight
Driving

kr540

Average price

Cheapest

kr4441

Average price

kr351

Average price

(fuel + tolls)

8h 33m

Average total duration

8h 3m

Onboard

+

30m

Additional time*

5h 17m

Average total duration

Fastest

3h 17m

Onboard

+

2h 0m

Additional time*

4h 0m

Average total duration

(door-to-door)

Greyhound

Most popular bus company

United

Most popular airline

Your own car or car rental

Direct Options

Direct Options

Direct Options

The cheapest way to travel from Iowa City, IA to St. Louis, MO is a bus with an average price of kr540.

This is compared to other travel options from Iowa City, IA to St. Louis, MO:

A bus is kr3901 less than a flight for this route with tickets for a flight from Iowa City, IA to St. Louis, MO costing on average kr4441.

The fastest way to travel from Iowa City, IA to St. Louis, MO is by flight with an average journey time of 3h 17m.

Other travel options to St. Louis, MO take longer:

Bus takes on average 8h 3m.

It's helpful to compare your options as there are 2 ways to travel between Iowa City, IA and St. Louis, MO including taking a bus and flight.
We recommend using the bus as it is the most popular way to get from Iowa City, IA to St. Louis, MO among Omio's users.
Take the bus. On this route, it's both cheaper and quicker than driving.

You'll arrive about -5h -3m sooner (8h 3m by bus vs 4h 0m by car) and save roughly kr-188.27 compared to fuel and tolls (kr540 vs kr351). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.

Direct coaches are operated by Greyhound, Infobus.

Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.

Iowa City, IA to St. Louis, MO Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
Greyhound
Departure Time
12:30AM
Arrival Time
05:35AM
Duration
5h05
Departure days
Tue, Thu, Fri, Sat, Sun
Cheapest price
kr237
Operator
Greyhound
Departure Time
12:25PM
Arrival Time
05:35PM
Duration
5h10
Departure days
Tue, Sun
Cheapest price
kr199
Operator
FlixBus
Departure Time
05:40PM
Arrival Time
12:25PM
Duration
18h45
Departure days
Fri
Cheapest price
kr1158
Operator
FlixBus
Departure Time
08:45PM
Arrival Time
12:25PM
Duration
15h40
Departure days
Fri
Cheapest price
kr695

Live departures

Iowa City, IA to St. Louis, MO bus times

The table below shows live departures for Iowa City, IA to St. Louis, MO buses for today, Friday, August 28. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
FlixBus5:40 PM Iowa City, IA
18h45
12:25 PM St. Louis, MO0 transfersDirect
FlixBus8:45 PM Iowa City, IA
15h40
12:25 PM St. Louis, MO0 transfersDirect
Saturday, August 29
Greyhound12:30 AM Iowa City, IA
5h05
5:35 AM St. Louis, MO0 transfersDirect

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Iowa City, IA to St. Louis, MO by bus or flight

Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Sat
Aug 29
Sun
Aug 30
Mon
Aug 31
Tue
Sep 01
Wed
Sep 02
Thu
Sep 03
Fri
Sep 04

Why should you book Iowa City, IA to St. Louis, MO buses with Omio?

Greyhound as well as Infobus offer buses services from Iowa City, IA to St. Louis, MO.
Omio is an official ticket reseller for all your travel options from Iowa City, IA to St. Louis, MO.

Why book with Omio vs Greyhound?

  • Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of Infobus to find the best option for your trip from Iowa City, IA to St. Louis, MO.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Iowa City, IA to St. Louis, MO.

Why book with Omio over Wanderu, Busbud or Checkmybus?

  • Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Iowa City, IA to St. Louis, MO.

Journey information

Overview: Bus from Iowa City, IA to St. Louis, MO

USAUSA
USAUSA
Icon of bus

Buses from Iowa City, IA to St. Louis, MO run on average 2 times per day, taking around 8h 3m. Cheap bus tickets for this journey start at kr227 if you book in advance.

There are 1 buses per day. The earliest bus runs at 07:50, the last at 23:30. The fastest bus covers the 221 miles (356 km) distance in 5h 5m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
221 miles (356 km)
Average bus duration
8h 3m
Cheapest ticket price
kr227
Buses per day
2
Direct buses
1
Fastest bus
5h 5m
First bus
7:50 AM
Last bus
11:30 PM
Cheapest Month
May
Cheapest Day
Sun
High Season
Apr - Jun
Low Season
Jul - Sep
Busiest Day
Thu
Least Busy Day
Thu
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: Greyhound, FlixBus, Infobus from Iowa City, IA to St. Louis, MOYou can travel by bus between Iowa City, IA to St. Louis, MO with Greyhound, FlixBus, Infobus for as low as kr227. When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
10h 30m
Cheapest FlixBus Price
kr571
FlixBus frequency
2 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.

Infobus

About
Infobus is an international IT company that operates as an online service for finding and purchasing bus, train, and plane tickets, rather than being a bus company itself. Established in 2002, Infobus acts as an intermediary between passengers and various transport carriers, particularly helping smaller bus companies offer online booking services. They utilize their own "BusSystem" to manage routes and ticket sales globally. Infobus covers over 30 countries and 300 cities, offering a wide range of routes and daily departures. While amenities can vary by carrier, Infobus aims to provide affordable and convenient travel with features like online booking, 24/7 support, and prompt notifications.
Luggage & cancellation policy
Average Infobus Duration
6h 40m
Cheapest Infobus Price
kr663
Infobus frequency
1 a day
Luggage included
One carry-on bag up to 5kg (40x20x25) and one checked bag up to 20kg (50x30x80).
Additional luggage
10€ per additional bag.
Cancellation Policy
You can cancel your ticket up to 24 hours before departure for a partial refund. Cancellations within 24 hours may incur a fee.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Transport for wheelchairs and mobility aids.
Bikes
Bikes are allowed; may require prior reservation and an additional fee.
Pets
Small pets allowed in carriers; larger pets may require a separate ticket.

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
5h 5m
Cheapest Greyhound Price
kr227
Greyhound frequency
1 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.

Complete guide to St. Louis, MO

Things to do in St. Louis, MO

Discover the best of St. Louis, MO — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect St. Louis, MO trip today.

  • Must visit

Saint Louis Art Museum

Vast art museum in Forest Park with global collections from antiquity to modern works and strong free general admission.

  • Recommended

Missouri History Museum

Leading history museum covering St. Louis, Missouri, and national stories through rotating exhibitions in Forest Park.

  • Recommended

Saint Louis Science Center

Interactive science museum with hands-on exhibits, planetarium, and family-friendly displays near Forest Park.

United States dollar ($)

Moderate for U.S. city breaks: hotels and dining are reasonable, transit is limited, and attractions often cost less than in larger U.S. tourist cities.

Average meal costs

Budget
$10-15 for fast food or casual lunch.
Mid-range
$20-35 per person for a mid-range restaurant meal.
Fine dining
$60+ per person at upscale restaurants.
Coffee
$3-5 for coffee or cappuccino.

Tipping culture

Tip 18-20% at restaurants, $1-2 per drink at bars, and 10-15% for taxis. Cafes often have tip jars or screen prompts.

FAQs: Bus from Iowa City, IA to St. Louis, MO

Find answers to the most common questions about traveling from Iowa City, IA to St. Louis, MO by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Iowa City, IA to St. Louis, MO can start from as little as kr227 when you book in advance. The average bus ticket price for Iowa City, IA to St. Louis, MO is kr540 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Iowa City, IA to St. Louis, MO is 5h 5m to travel the 221 miles (356 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Iowa City, IA to St. Louis, MO leaves at 7:50 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Iowa City, IA to St. Louis, MO leaves at 11:30 PM.
Yes, there are 1 direct buses a day from Iowa City, IA to St. Louis, MO with Greyhound, Infobus. Schedules can vary on holidays or weekends with fewer direct buses.
When taking a bus from Iowa City, IA to St. Louis, MO, you can count on Greyhound, Infobus for the best way to get you to St. Louis, MO. You can also check all possible bus companies who offer a service between Iowa City, IA and St. Louis, MO and compare the amenities they offer before buying a bus ticket.
When departing from Iowa City, IA , you have various bus station options to start your journey from including Iowa City, S Riverside Dr (Kum & Go), IA, Iowa City, IA, Iowa City, E Court St (Greyhound Bus Station), IA . When arriving in St. Louis, MO , you can end your journey in bus stations like St. Louis, S 15th St (Civic center), St. Louis, MO .Passengers board the bus most frequently from Iowa City, S Riverside Dr (Kum & Go), IA, which is located around 0 miles (1 km) away from the city centre, and they get off the bus at St. Louis, S 15th St (Civic center), located 0 away from the city centre.
A trip to St. Louis, MO from Iowa City, IA is worth doing but not as a day trip with a journey time of 5h 5m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Iowa City, IA to St. Louis, MO is May.
It's helpful to compare your options as there are 2 ways to travel between Iowa City, IA and St. Louis, MO including taking a bus and flight.
Yes, the following accessibility options are available when taking the bus from Iowa City, IA to St. Louis, MO:
  • Infobus
    • Assistance
    • Priority seating
    • Transport for wheelchairs and mobility aids.
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Iowa City, IA to St. Louis, MO for bus company Greyhound, Infobus.
Whether you can cancel your bus ticket from Iowa City, IA to St. Louis, MO depends on the bus companies:
  • Infobus
    • You can cancel your ticket up to 24 hours before departure for a partial refund. Cancellations within 24 hours may incur a fee.
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound, Infobus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Iowa City, IA to St. Louis, MO.
Yes, the following luggage options are included when booking a bus ticket from Iowa City, IA to St. Louis, MO:
  • Infobus
    • One carry-on bag up to 5kg (40x20x25) and one checked bag up to 20kg (50x30x80).
  • Greyhound
    • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Iowa City, IA to St. Louis, MO:
  • Infobus
    • 10€ per additional bag.
  • Greyhound
    • $15 per additional bag.
Yes, you can bring your pet on the bus from Iowa City, IA to St. Louis, MO. The following conditions apply:
  • Infobus
    • Small pets allowed in carriers
    • larger pets may require a separate ticket.
You can reserve your seat on the bus from Iowa City, IA to St. Louis, MO with the following bus company: Greyhound, Infobus
Yes, there are USB plugs on board the bus from Iowa City, IA to St. Louis, MO with the following bus company: Greyhound, Infobus.
Yes, there is Wifi on board the bus from Iowa City, IA to St. Louis, MO with the following bus company: Greyhound, Infobus.
Since neither Iowa City, IA nor St. Louis, MO are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the bus as it is the most popular way to get from Iowa City, IA to St. Louis, MO among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In St. Louis, MO, travelers should be cautious in certain neighborhoods with higher crime rates, especially after dark. Common safety concerns include petty theft, pickpocketing, and occasional scams targeting visitors near popular attractions like the Gateway Arch. It’s advisable to stay in well-populated areas, avoid displaying valuables openly, and use reputable transportation services to minimize risks.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from Iowa City, IA to St. Louis, MO

Most Iowa City, IA to St. Louis, MO buses use the Iowa City, S Riverside Dr (Kum & Go) to St. Louis, S 15th St (Civic center) station pair, with some services arriving at St. Louis. Use this guide to compare Iowa City, IA and St. Louis, MO bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.

Departure bus stations in Iowa City
Arrival bus stations in St. Louis

Which Iowa City, IA station do buses to St. Louis, MO leave from?

Buses from Iowa City, IA to St. Louis, MO leave from Iowa City, S Riverside Dr (Kum & Go). The station is 0 miles (1 km) from Iowa City, IA city centre at S Riverside Dr, Iowa City, IA, USA.
Iowa City, S Riverside Dr (Kum & Go)S Riverside Dr, Iowa City, IA, USAWifiParkingDiningATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to Iowa City, S Riverside Dr (Kum & Go) from Iowa City city centre

Iowa City, S Riverside Dr (Kum & Go) is 1 km from Iowa City city centre. Public transport options include:

TRUE

Iowa City, S Riverside Dr (Kum & Go) bus station facilities and services

Iowa City, S Riverside Dr (Kum & Go) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Food and drink

Food options include: Convenience store available at the station.

Wi-Fi and ATMs

Wi-Fi is available at Iowa City, S Riverside Dr (Kum & Go). ATMs are available at Iowa City, S Riverside Dr (Kum & Go).

Tickets and information

Ticket office support is available at Iowa City, S Riverside Dr (Kum & Go).

Parking, taxis and toilets

Available at Iowa City, S Riverside Dr (Kum & Go): Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at Iowa City, S Riverside Dr (Kum & Go): Station is accessible for people with disabilities.

Iowa City, E Court St (Greyhound Bus Station)170 E Court St, Iowa City, IA 52240, USAWifiParkingATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to Iowa City, E Court St (Greyhound Bus Station) from Iowa City city centre

Bus12 · 5m · every ~2 min

Iowa City, E Court St (Greyhound Bus Station) bus station facilities and services

Iowa City, E Court St (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Wi-Fi and ATMs

Wi-Fi is available at Iowa City, E Court St (Greyhound Bus Station). ATMs are available at Iowa City, E Court St (Greyhound Bus Station).

Tickets and information

Ticket office support is available at Iowa City, E Court St (Greyhound Bus Station).

Parking, taxis and toilets

Available at Iowa City, E Court St (Greyhound Bus Station): Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at Iowa City, E Court St (Greyhound Bus Station): Bus station is wheelchair accessible.

Most popular bus connections from Iowa City, IA

More options for your journey from Iowa City, IA to St. Louis, MO

Here are some other resources that might have the information you need

HomeBusesBuses in USABus tickets to St. Louis, MOIowa City, IA to St. Louis, MO bus

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