- Must visit
Saint Louis Art Museum
Vast art museum in Forest Park with global collections from antiquity to modern works and strong free general admission.
Cheapest price on Aug 30
kr365
Average ticket price on Aug 30
kr365
Fastest journey on Aug 30
5 h 5 m
Average journey duration on Aug 30
5 h 5 m
Buses on Aug 30
1
Distance
356 km
The best way to find a cheap bus ticket from Iowa City, IA to St. Louis, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Iowa City, IA to St. Louis, MO will cost around kr365 if you buy it on the day, but the cheapest tickets can be found for only kr365.
On Sun, Aug 30, we found 1 buses from Iowa City, IA to St. Louis, MO, including 1 direct services.
On Sun, Aug 30 the direct buses cover the 356 km distance in an average of 5 h 5 m but if you time it right, some buses will get you there in just 5 h 5 m .
On Sun, Aug 30 the slowest buses will take 5 h 5 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Omio recommends booking the bus as it is the most popular option from Iowa City, IA to St. Louis, MO among Omio's users. If you are prioritising price, take the bus, with an average ticket price of kr540 For those with little time, consider booking a flight, which has an average total journey time of 5h 17m. Average ticket prices depend on the travel mode: a bus costs an average of kr540, while a flight costs an average of kr4441.
Distance: 221 miles (356 km)
Most popular Bus | Flight | Driving |
|---|---|---|
kr540 Average price Cheapest | kr4441 Average price | kr351 Average price (fuel + tolls) |
8h 33m Average total duration 8h 3m Onboard + 30m Additional time* | 5h 17m Average total duration Fastest 3h 17m Onboard + 2h 0m Additional time* | 4h 0m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Iowa City, IA to St. Louis, MO:
A bus is kr3901 less than a flight for this route with tickets for a flight from Iowa City, IA to St. Louis, MO costing on average kr4441.
Other travel options to St. Louis, MO take longer:
Bus takes on average 8h 3m.
You'll arrive about -5h -3m sooner (8h 3m by bus vs 4h 0m by car) and save roughly kr-188.27 compared to fuel and tolls (kr540 vs kr351). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by Greyhound, Infobus.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:30AM | Arrival Time 05:35AM | Duration 5h05 | Departure days Tue, Thu, Fri, Sat, Sun | Cheapest price kr237 |
Operator Greyhound | Departure Time 12:25PM | Arrival Time 05:35PM | Duration 5h10 | Departure days Tue, Sun | Cheapest price kr199 |
Operator FlixBus | Departure Time 05:40PM | Arrival Time 12:25PM | Duration 18h45 | Departure days Fri | Cheapest price kr1158 |
Operator FlixBus | Departure Time 08:45PM | Arrival Time 12:25PM | Duration 15h40 | Departure days Fri | Cheapest price kr695 |
The table below shows live departures for Iowa City, IA to St. Louis, MO buses for today, Friday, August 28. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 5:40 PM Iowa City, IA | 18h45 | 12:25 PM St. Louis, MO | 0 transfersDirect | |
![]() | 8:45 PM Iowa City, IA | 15h40 | 12:25 PM St. Louis, MO | 0 transfersDirect | |
| Saturday, August 29 | |||||
![]() | 12:30 AM Iowa City, IA | 5h05 | 5:35 AM St. Louis, MO | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Iowa City, IA to St. Louis, MO run on average 2 times per day, taking around 8h 3m. Cheap bus tickets for this journey start at kr227 if you book in advance.
There are 1 buses per day. The earliest bus runs at 07:50, the last at 23:30. The fastest bus covers the 221 miles (356 km) distance in 5h 5m.
Distance 221 miles (356 km) |
Average bus duration 8h 3m |
Cheapest ticket price kr227 |
Buses per day 2 |
Direct buses 1 |
Fastest bus 5h 5m |
First bus 7:50 AM |
Last bus 11:30 PM |
Cheapest Month May |
Cheapest Day Sun |
High Season Apr - Jun |
Low Season Jul - Sep |
Busiest Day Thu |
Least Busy Day Thu |
Discover the best of St. Louis, MO — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect St. Louis, MO trip today.
Vast art museum in Forest Park with global collections from antiquity to modern works and strong free general admission.
Leading history museum covering St. Louis, Missouri, and national stories through rotating exhibitions in Forest Park.
Interactive science museum with hands-on exhibits, planetarium, and family-friendly displays near Forest Park.
Lively downtown riverfront district with trails, views of the Arch, public art, and access to major historic sites.
Large urban park with trails, lakes, zoo access, and major museums, ideal for walking between top attractions.
Beloved neighborhood park with formal lily ponds, pavilions, and one of the city's most photographed landscapes.
A thin, cracker-like crust pizza cut into squares and topped with Provel cheese, a St. Louis original loved for its distinct texture and tangy flavor.
Crisp, breaded ravioli said to be born on The Hill, usually served with marinara. It is a signature St. Louis Italian-American appetizer.
Sticky butter cake with a dense base and gooey sweet top. A longtime St. Louis bakery favorite often enjoyed for breakfast or dessert.
Refined contemporary restaurant with tasting menus and strong national acclaim. Elegant fine dining focused on seasonal Midwestern ingredients.
Beloved frozen custard stand serving concretes and sundaes since 1929. Casual, nostalgic, and one of the city's iconic dessert stops.
Popular smokehouse known for St. Louis barbecue, especially ribs, brisket, and pork steak, in a polished but relaxed atmosphere.
Moderate for U.S. city breaks: hotels and dining are reasonable, transit is limited, and attractions often cost less than in larger U.S. tourist cities.
Tip 18-20% at restaurants, $1-2 per drink at bars, and 10-15% for taxis. Cafes often have tip jars or screen prompts.
Find answers to the most common questions about traveling from Iowa City, IA to St. Louis, MO by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.

Most Iowa City, IA to St. Louis, MO buses use the Iowa City, S Riverside Dr (Kum & Go) to St. Louis, S 15th St (Civic center) station pair, with some services arriving at St. Louis. Use this guide to compare Iowa City, IA and St. Louis, MO bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Iowa City, S Riverside Dr (Kum & Go) is 1 km from Iowa City city centre. Public transport options include:
Iowa City, S Riverside Dr (Kum & Go) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Convenience store available at the station.
Wi-Fi is available at Iowa City, S Riverside Dr (Kum & Go). ATMs are available at Iowa City, S Riverside Dr (Kum & Go).
Ticket office support is available at Iowa City, S Riverside Dr (Kum & Go).
Available at Iowa City, S Riverside Dr (Kum & Go): Parking, Taxis, WC.
Accessibility facilities are available at Iowa City, S Riverside Dr (Kum & Go): Station is accessible for people with disabilities.
Iowa City, E Court St (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Iowa City, E Court St (Greyhound Bus Station). ATMs are available at Iowa City, E Court St (Greyhound Bus Station).
Ticket office support is available at Iowa City, E Court St (Greyhound Bus Station).
Available at Iowa City, E Court St (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Iowa City, E Court St (Greyhound Bus Station): Bus station is wheelchair accessible.
St. Louis, S 15th St (Civic center) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at St. Louis, S 15th St (Civic center). ATMs are available at St. Louis, S 15th St (Civic center).
Ticket office support is available at St. Louis, S 15th St (Civic center).
Available at St. Louis, S 15th St (Civic center): Parking, Taxis, WC.
Accessibility facilities are available at St. Louis, S 15th St (Civic center): Wheelchair accessible routes available.
St. Louis has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: There are food vendors in the station.
Free wifi is available in the waiting area. ATMs are aTM available near the entrance.
Ticket office support is available at St. Louis.
Available at St. Louis: Parking, Taxis, WC.
Accessibility facilities are available at St. Louis: The station is accessible to wheelchairs.
Here are some other resources that might have the information you need