- Must visit
California Academy of Sciences
Renowned science museum with rainforest dome, aquarium, and planetarium. Interactive exhibits make it a standout for all ages.
Cheapest price
$525
Average price
$525
Fastest journey
1 d 20 h
Average duration
1 d 20 h
Buses per day
1
Distance
2662 km
The best way to find a cheap bus ticket from Iowa City, IA to San Francisco, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Iowa City, IA to San Francisco, CA will cost around $525 if you buy it on the day, but the cheapest tickets can be found for only $525.
It's difficult to get from Iowa City, IA to San Francisco, CA without transferring at least 2 times.


Omio recommends booking the bus as it is the most popular option from Iowa City, IA to San Francisco, CA among Omio's users. If you are prioritising price take the bus with prices starting from $525. For those with little time consider booking a bus which can get you there in 44h 0m. The ticket price range depends on the travel mode: a bus costs an average of $525, and a bus costs an average of $525.
Distance: 1654 miles (2662 km)
Most popular Bus | Driving |
|---|---|
$525 Average price Cheapest | $383 Average price (fuel + tolls) |
44h 30m Average total duration Fastest 44h 0m Onboard + 30m Additional time* | 27h 51m Average total duration (door-to-door) |
Direct Options | Direct Options |
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound USA | Departure Time 04:25PM | Arrival Time 12:25PM | Duration 44h00 | Departure days Tue, Wed, Thu, Fri, Sat | Cheapest price $525 |
The table below shows live departures for Iowa City, IA to San Francisco, CA buses for today, Tuesday, July 14. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 4:25 PM Iowa City, IA | 44h00 | 12:25 PM San Francisco, CA | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Iowa City, IA to San Francisco, CA run on average 2 times per day, taking around 44h 0m. Cheap bus tickets for this journey start at $525 (€433) if you book in advance.
The earliest bus runs at 08:20, the last at 22:40. The fastest bus covers the 1654 miles (2662 km) distance in 44h 0m.
Distance 1654 miles (2662 km) |
Average bus duration 44h 0m |
Cheapest ticket price $525 (€433) |
Buses per day 2 |
Fastest bus 44h 0m |
First bus 8:20 AM |
Last bus 10:40 PM |
Cheapest Month Sep |
Cheapest Day Sat |
High Season Jul - Sep |
Low Season Jul - Sep |
Discover the best of San Francisco — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect San Francisco trip today.
Renowned science museum with rainforest dome, aquarium, and planetarium. Interactive exhibits make it a standout for all ages.
Major fine arts museum in Golden Gate Park with American art, textiles, and a panoramic tower. A classic cultural highlight.
Leading modern and contemporary art museum with landmark architecture and strong global collections. Essential for art-focused visitors.
Large urban park with gardens, lakes, museums, and trails. It is a must for relaxing, walking, and seeing several major attractions.
Steeply curving block lined with flowers and grand homes. This famous street offers classic photos and a quintessential San Francisco scene.
Popular waterfront promenade with bay views, piers, and ferries. Great for walking, people-watching, and connecting to nearby sights.
A crusty loaf with a tangy flavor shaped by the city’s historic wild yeast culture. It is one of San Francisco’s most iconic foods.
Fresh local Dungeness crab, often cracked and served simply or in cioppino. It is a Bay Area seasonal specialty tied to the fishing waterfront.
A tomato-based seafood stew created by Italian American fishermen in North Beach. It is a classic San Francisco dish built from the day’s catch.
Celebrated fine dining destination known for inventive tasting menus and polished service in an elegant, intimate setting.
Historic North Beach seafood house famous for cioppino, crab, and old-school San Francisco waterfront charm.
Legendary Mission taqueria known for large Mission-style burritos and a lively, no-frills local atmosphere.
Very high hotel, dining, and transport costs make San Francisco pricier than most US cities and many major tourist destinations.
Tip 18-20% at restaurants, 15-20% for taxis, and round up or tip $1 at cafes for good service.
Find answers to the most common questions about traveling from Iowa City, IA to San Francisco, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Francisco, CA, this guide helps you travel smarter and with confidence.

Most Iowa City, IA to San Francisco, CA buses use the Iowa City, S Riverside Dr (Kum & Go) to San Francisco, Townsend Street / 5th Street station pair, with some services arriving at San Francisco, Transit Center Bay 29. Use this guide to compare Iowa City, IA and San Francisco, CA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need