- Must visit
Walker Art Center
Major contemporary art museum with acclaimed architecture, rotating exhibitions, and one of the top collections in the region.
Omio recommends booking the train as it is the most popular option from Greenville, SC to Minneapolis, MN among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $180 For those with little time, consider booking a flight, which has an average total journey time of 6h 43m. Average ticket prices depend on the travel mode: a bus costs an average of $180, while a flight costs an average of $714.
Distance: 904 miles (1456 km)
Most popular Train | Bus | Flight | Driving |
|---|---|---|---|
$706 Average price | $180 Average price Cheapest | $714 Average price | $238 Average price (fuel + tolls) |
37h 36m Average total duration 37h 6m Onboard + 30m Additional time* | 29h 12m Average total duration 28h 42m Onboard + 30m Additional time* | 6h 43m Average total duration Fastest 4h 43m Onboard + 2h 0m Additional time* | 16h 54m Average total duration (door-to-door) |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Greenville, SC to Minneapolis, MN:
A bus is $526 less than a train for this route with tickets for a train from Greenville, SC to Minneapolis, MN costing on average $706.
A bus is $533 less than a flight for this route with tickets for a flight from Greenville, SC to Minneapolis, MN costing on average $714.
Other travel options to Minneapolis, MN take longer:
Bus takes on average 28h 42m.
Train takes on average 37h 6m.
Tickets start at around $706 compared to roughly $238 in fuel and tolls — a saving of about $-468.23. The journey takes 37h 6m versus 16h 54m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Greenville, SC to Minneapolis, MN run on average 2 times per day, taking around 37h 6m. Cheap train tickets for this journey start at $357 but you can travel from only $108 by bus.
The earliest train runs at 02:23, the last at 08:50. The fastest train covers the 904 miles (1456 km) distance in 37h 3m.
Distance 904 miles (1456 km) |
Average train duration 37h 6m |
Cheapest ticket price $357 |
Trains per day 2 |
Fastest train 37h 3m |
First train 2:23 AM |
Last train 8:50 AM |
Cheapest Month May |
Cheapest Day Sun |
High Season Jul - Sep |
Low Season Jan - Mar |
Discover the best of Minneapolis, MN — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Minneapolis, MN trip today.
Major contemporary art museum with acclaimed architecture, rotating exhibitions, and one of the top collections in the region.
Smithsonian-affiliated history museum inside Mill City Museum, exploring Minneapolis industry, flour, and riverfront development.
Leading fine arts museum with global collections, period rooms, and strong Native, Asian, and modern works.
Famous urban sculpture garden with the Spoonbridge and Cherry, linking art, skyline views, and easy walking paths.
Lakeside park with beaches, trails, and classic Minneapolis scenery; ideal for walks, biking, and sunset views.
Historic riverfront district with cobbled character, trails, bridges, and excellent views of the Mississippi and downtown.
The iconic Minnesota hot dish: ground beef, vegetables, cream soup, and tater tots baked until crisp. A beloved Upper Midwest comfort food common at family gatherings.
A Scandinavian potato flatbread central to Minnesota holiday tables. It reflects the region’s strong Nordic heritage and is often served with butter or sugar.
Minnesota’s famous wild rice soup combines nutty native wild rice with cream, vegetables, and often chicken. It highlights an ingredient deeply tied to the state.
Acclaimed fine-dining destination showcasing Minnesota ingredients with refined tasting menus. Elegant, polished, and nationally respected.
Long-running restaurant known for excellent walleye and classic supper-club style. Comfortable setting near Minnehaha Falls.
Legendary South Minneapolis tavern famous for the original Juicy Lucy. Casual, lively, and essential for a classic local burger experience.
Moderate for a major US city. Hotels, dining, and attractions are mid-priced, while transit is affordable and budget eats are easy to find.
Tip 18-20% at restaurants, $1-2 per drink at bars, 10-15% for taxis, and spare change or $1 at cafes.
Find answers to the most common questions about traveling from Greenville, SC to Minneapolis, MN by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Minneapolis, MN, this guide helps you travel smarter and with confidence.

Most Greenville, SC to Minneapolis, MN trains use the Greenville Station to Union Depot station pair. Use this guide to compare Greenville, SC and Minneapolis, MN train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Greenville Station is 1 km from Greenville city centre. Public transport options include:
Greenville Station has practical services for this route, including Wifi, Lockers, Parking, Dining, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Information Desk, and Luggage Carts.
Food options include: Soby's, Larkin's on the River
Free.
Ticket office support is available at Greenville Station. Information desks are located in the main hall.
Luggage storage is available at Greenville Station. Lost and found is available at the station.
Available at Greenville Station: Parking, Taxis, WC.
Available at Greenville Station: Bike Parking, Bike Rental.
Accessibility facilities are available at Greenville Station: Ramps, assistance.
Nearby hotels include The Westin Poinsett, Greenville, Courtyard Greenville Downtown, Hyatt Regency Greenville.
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