Frederick, MD to Charleston, SC bus with Greyhound

Wed, Jan 28
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1,000+ travel companies
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The cheapest and fastest buses from Frederick, MD to Charleston, SC

Showing times and prices for Jan 29

Cheapest price

$240

Average price

$240

Fastest journey

1 d 15 h 11 m

Average duration

1 d 15 h 11 m

Buses per day

1

Distance

772 km

Cheap tickets

The best way to find a cheap bus ticket from Frederick, MD to Charleston, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Frederick, MD to Charleston, SC will cost around $240 if you buy it on the day, but the cheapest tickets can be found for only $240.

Fast buses

It's difficult to get from Frederick, MD to Charleston, SC without transferring at least 4 times.

Greyhound USA
12:30AM39h11
Frederick, MD
03:41PMCharleston, SC
$2401One-way
4 transfers

Travel Information

Compare bus for Frederick, MD to Charleston, SC

Omio recommends booking the flight as it is the most popular option from Frederick, MD to Charleston, SC among Omio's users. If you are prioritising price take the bus with prices starting from €105. For those with little time consider booking a flight which can get you there in 3h 32m. The ticket price range depends on the travel mode: a bus costs an average of €105, and a train costs an average of €145.

Distance: 479 miles (772 km)

Compare bus with

Bus
Most popular
Flight
Train

€105

Average price

Cheapest

€106

Average price

€145

Average price

15h 5m

Average total duration

14h 35m

Onboard

+

30m

Additional time*

6h 32m

Average total duration

Fastest

3h 32m

Onboard

+

3h 0m

Additional time*

17h 42m

Average total duration

17h 12m

Onboard

+

30m

Additional time*

Direct Options

Direct Options

Direct Options

Live departures

Frederick, MD to Charleston, SC bus times

The table below shows live departures for Frederick, MD to Charleston, SC buses for today, Wednesday, January 28. You can also manually refresh the results below to see updated bus journeys.

Last updated at 12:00 AM
ProviderDepartsDurationArrivesTransfers
Tickets
greyhound12:30 AM Frederick, MD
39h11
3:41 PM Charleston, SC4 transfers

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Frederick, MD to Charleston, SC by bus

Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Thu
Jan 29
Fri
Jan 30
Sat
Jan 31
Sun
Feb 01
Mon
Feb 02
Tue
Feb 03
Wed
Feb 04

Why should you book Frederick, MD to Charleston, SC buses with Omio?

Greyhound operates all buses services from Frederick, MD to Charleston, SC.
Omio is an official ticket reseller for all your travel options from Frederick, MD to Charleston, SC.

Why book with Omio vs Greyhound?

  • Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of to find the best option for your trip from Frederick, MD to Charleston, SC.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.

Why book with Omio over Wanderu?

    Journey information

    Overview: Bus from Frederick, MD to Charleston, SC

    USAUSA
    USAUSA
    Icon of bus

    Buses from Frederick, MD to Charleston, SC run on average 2 times per day, taking around 14h 35m. Cheap bus tickets for this journey start at $134 (€105) if you book in advance.

    The earliest bus runs at 04:30, the last at 04:30. The fastest bus covers the 479 miles (772 km) distance in 14h 35m.

    Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
    Price information
    Distance
    479 miles (772 km)
    Average bus duration
    14h 35m
    Cheapest ticket price
    $134 (€105)
    Buses per day
    2
    Fastest bus
    14h 35m
    First bus
    04:30
    Last bus
    04:30
    Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
    Price information

    Bus providers: Greyhound from Frederick, MD to Charleston, SCYou can travel by bus between Frederick, MD to Charleston, SC with Greyhound for as low as $134 (€105). When you search for schedules and tickets, Omio will show you the best journey

    Greyhound

    About
    Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
    Luggage & cancellation policy
    Average Duration
    39h 8m
    Cheapest Price
    $240 (€189)
    Greyhound frequency
    1 a day
    Luggage included
    One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
    Additional luggage
    $15 per additional bag.
    Cancellation Policy
    You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
    Amenities on board the bus
    Wifi
    Food sold onboard
    Seat reservation
    Toilets
    USB plugs
    Accessibility
    Assistance; Priority seating; Wheelchair-accessible buses.
    Bikes
    Bikes are allowed.
    Learn more about Greyhound

    FAQs: Bus from Frederick, MD to Charleston, SC

    Find answers to the most common questions about traveling from Frederick, MD to Charleston, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Charleston, SC, this guide helps you travel smarter and with confidence.

    FAQs
    Cheap bus tickets from Frederick, MD to Charleston, SC can start from as little as $276 (€215) when you book in advance. The average bus ticket price for Frederick, MD to Charleston, SC is $276 (€215); however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
    On average the Frederick, MD to Charleston, SC bus time is 39 h 8 min   covering the 478 mile (771 km) long journey, but the journey time can vary depending on specific dates or if traveling on weekends and holidays.
    The bus from Frederick, MD to Charleston, SC leaves at 12: 30AM. Plan your trip with the Journey Planner   from Omio.
    There are 2 buses a day from Frederick, MD to Charleston, SC which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
    Take the Frederick, MD to Charleston, SC bus with Greyhound. However, it's always good to check out all possible bus companies for the journey to Charleston, SC from Frederick, MD as there might be differences in the amenities they offer.
    The cheapest month to travel from Frederick, MD to Charleston, SC by bus is November.
    Yes, you can take a bus to Charleston, SC from Frederick, MD.
    Yes, the following accessibility options are available when taking the bus from Frederick, MD to Charleston, SC:
    • Greyhound
      • Assistance
      • Priority seating
      • Wheelchair-accessible buses.
    Yes, there are bathrooms on board the bus from Frederick, MD to Charleston, SC for bus company Greyhound.
    Yes, bikes are allowed on board the bus with bus company Greyhound.
    Whether you can cancel your bus ticket from Frederick, MD to Charleston, SC depends on the bus company:
    • Greyhound
      • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.

    To find the cheapest bus tickets for your trip from Frederick, MD to Charleston, SC, follow these tips:

    • Book in advance: Tickets are often cheaper when booked early.
    • Be flexible with dates and times: Traveling during off-peak hours or on weekdays can help you save money.
    • Use our search filters: Sort results by price to quickly identify the most affordable options.
    • Look for special deals or discounts: Check for promotions or discounts available on our website and app.

      • Start your search now and compare ticket prices to find the best deal!

      Yes, there is food available to purchase on board the bus from Frederick, MD to Charleston, SC.
      Yes, the following luggage options are included when booking a bus ticket from Frederick, MD to Charleston, SC:
      • Greyhound
        • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
      Yes, the following additional luggage options are available when booking a bus ticket from Frederick, MD to Charleston, SC:
      • Greyhound
        • $15 per additional bag.
      Unfortunately, pets are not allowed on the bus from Frederick, MD to Charleston, SC.
      You can reserve your seat on the bus from Frederick, MD to Charleston, SC with the following bus company: Greyhound
      Yes, there are USB plugs on board the bus from Frederick, MD to Charleston, SC with the following bus company: Greyhound.
      Yes, there is Wifi on board the bus from Frederick, MD to Charleston, SC with the following bus company: Greyhound.

      popular bus stations

      Popular bus stations from Frederick, MD to Charleston, SC

      Frederick
      Charleston
      The major bus station for departures in Frederick is Frederick, East Street (Transit Center). Find all the information you need to know about services, amenities and connections at Frederick, East Street (Transit Center) for your trip from Frederick to Charleston.
      Frederick, East Street (Transit Center)
      information

      More options for your journey from Frederick, MD to Charleston, SC

      Here are some other resources that might have the information you need

      Tickets and more information for coaches to Frederick, MD

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      HomeBusesBuses in USAFrederick, MD to Charleston, SC bus

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