- Must visit
The Charleston Museum
America’s first museum with natural history, decorative arts, and Charleston stories across several historic sites.
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The cheapest and fastest buses from Frederick, MD to Charleston, SC
Showing times, prices and bookable tickets for Oct 29
Cheapest price on Oct 29
$156
Average ticket price on Oct 29
$156
Fastest journey on Oct 29
1 d 8 h 5 m
Average journey duration on Oct 29
1 d 8 h 5 m
Buses on Oct 29
1
Distance
772 km
Cheap tickets
The best way to find a cheap bus ticket from Frederick, MD to Charleston, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Frederick, MD to Charleston, SC will cost around $156 if you buy it on the day, but the cheapest tickets can be found for only $156.
Fast buses
On Thu, Oct 29, we found 1 buses from Frederick, MD to Charleston, SC, including 1 direct services.
On Thu, Oct 29 the direct buses cover the 772 km distance in an average of 1 d 8 h 5 m but if you time it right, some buses will get you there in just 1 d 8 h 5 m .
On Thu, Oct 29 the slowest buses will take 1 d 8 h 5 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
2:25 PM 32h05 Frederick, MD 10:30 PM Charleston, SC $156 1 One-way 0 transfers
2:25 PM 32h05 Frederick, MD 10:30 PM Charleston, SC $156 1 One-way 0 transfers
Journey information
Overview: Bus from Frederick, MD to Charleston, SC
USAUSA
Buses from Frederick, MD to Charleston, SC run on average 3 times per day, taking around 16h 8m. Cheap bus tickets for this journey start at $87 (€73) if you book in advance.
The earliest bus runs at 00:35, the last at 21:34. The fastest bus covers the 479 miles (772 km) distance in 13h 24m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 479 miles (772 km) |
Average bus duration 16h 8m |
Cheapest ticket price $87 (€73) |
Buses per day 3 |
Fastest bus 13h 24m |
First bus 12:35 AM |
Last bus 9:34 PM |
Cheapest Month Nov |
Cheapest Day Wed |
High Season Jan - Mar |
Low Season Oct - Dec |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Frequently asked questions about your Frederick, MD to Charleston, SC trip
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Frederick, MD to Charleston, SC.
Cheap bus tickets from Frederick, MD to Charleston, SC can start from as little as $87 (€73) when you book in advance. The average bus ticket price for Frederick, MD to Charleston, SC is $113 (€95) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The earliest bus from Frederick, MD to Charleston, SC leaves at 12:35 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Frederick, MD to Charleston, SC leaves at 9:34 PM.
There are 3 buses a day from Frederick, MD to Charleston, SC which require at least one change with Greyhound, FlixBus. Schedules can vary on holidays or weekends with fewer buses.
Frederick, MD to Charleston, SC Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 04:35AM | Arrival Time 10:30PM | Duration 17h55 | Departure days Sun | Cheapest price $99 |
Operator Greyhound USA | Departure Time 10:25AM | Arrival Time 07:43PM | Duration 33h18 | Departure days Mon, Tue, Fri | Cheapest price $0 |
Operator FlixBus | Departure Time 02:25PM | Arrival Time 10:30PM | Duration 32h05 | Departure days Thu | Cheapest price $156 |
Operator FlixBus | Departure Time 03:25PM | Arrival Time 11:30PM | Duration 32h05 | Departure days Wed | Cheapest price $93 |
Live departures
Frederick, MD to Charleston, SC bus times
The table below shows live departures for Frederick, MD to Charleston, SC buses for today, Wednesday, October 28. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 3:25 PM Frederick, MD | 32h05 | 11:30 PM Charleston, SC | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Why should you book Frederick, MD to Charleston, SC buses with Omio?
Greyhound as well as FlixBus offer buses services from Frederick, MD to Charleston, SC.
Omio is an official ticket reseller for all your travel options from Frederick, MD to Charleston, SC.
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of FlixBus to find the best option for your trip from Frederick, MD to Charleston, SC.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
Why book with Omio over Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus to find the best option for your trip from Frederick, MD to Charleston, SC.
Bus providers: FlixBus, Greyhound from Frederick, MD to Charleston, SCYou can travel by bus between Frederick, MD to Charleston, SC with FlixBus, Greyhound for as low as $87 (€73). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
16h 55m
Cheapest FlixBus Price
$105 (€88)
FlixBus frequency
2 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
13h 24m
Cheapest Greyhound Price
$87 (€73)
Greyhound frequency
1 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Companies, tickets, and onboard amenities between Frederick, MD and Charleston, SC
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
When taking a bus from Frederick, MD to Charleston, SC, you can count on Greyhound, FlixBus for the best way to get you to Charleston, SC. You can also check all possible bus companies who offer a service between Frederick, MD and Charleston, SC and compare the amenities they offer before buying a bus ticket.
Yes, the following accessibility options are available when taking the bus from Frederick, MD to Charleston, SC:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Frederick, MD to Charleston, SC for bus company Greyhound, FlixBus.
Whether you can cancel your bus ticket from Frederick, MD to Charleston, SC depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company {providersWithBike}.
Yes, there is food available to purchase on board the bus from Frederick, MD to Charleston, SC.
Yes, the following luggage options are included when booking a bus ticket from Frederick, MD to Charleston, SC:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Frederick, MD to Charleston, SC:
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Frederick, MD to Charleston, SC. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from Frederick, MD to Charleston, SC with the following bus company: Greyhound, FlixBus
Yes, there are USB plugs on board the bus from Frederick, MD to Charleston, SC with the following bus company: Greyhound, FlixBus.
Yes, there is Wifi on board the bus from Frederick, MD to Charleston, SC with the following bus company: Greyhound, FlixBus.
Complete guide to Charleston, SC
Things to do in Charleston, SC
Discover the best of Charleston, SC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Charleston, SC trip today.
- Must visit
Gibbes Museum of Art
Leading Southern museum for contemporary art, known for bold exhibitions and strong local creative connections.
- Must visit
International African American Museum
Powerful museum on Gadsden’s Wharf interpreting the African American journey and Charleston’s global significance.
- Must visit
The Battery
Legendary waterfront promenade lined with antebellum homes, harbor breezes, and some of Charleston’s best views.
- Must visit
East Battery
Historic defensive seawall and walk beside White Point Garden, ideal for sunset, mansions, and harbor panoramas.
- Must visit
Charleston City Market
Lively pedestrian-friendly market district known for crafts, architecture, and easy access to major downtown sights.
- Gluten-free
Perloo
A Lowcountry rice dish with shrimp, sausage, or chicken simmered in rich broth. It reflects Charleston's Gullah Geechee and coastal cooking traditions.
- Gluten-free
Shrimp And Grits
Stone-ground grits cooked creamy and topped with local shrimp, often with bacon or gravy. It is one of Charleston's signature brunch and supper dishes.
She-Crab Soup
A rich soup of blue crab, crab roe, cream, and sherry. This classic Charleston dish is closely tied to the city's historic seafood culture.
Circa 1886 Restaurant
Historic fine-dining restaurant focused on seasonal Lowcountry cuisine. Known for polished Southern hospitality and dishes using regional ingredients.
The Ordinary
Upscale seafood restaurant celebrated for local oysters and inventive Lowcountry dishes. Stylish, lively, and one of Charleston's best-known dining rooms.
Magnolias
Refined Southern restaurant in the Historic District, known for shrimp and grits, seafood, and polished service in an elegant setting.
US Dollar ($)
Moderate for a US coastal city; hotels and dining in the historic district run higher, while transit is limited and many visitors rely on walking, rideshare, or car hire.
Average meal costs
- Budget
- $10-18 for fast food or casual lunch.
- Mid-range
- $25-45 per person for a restaurant meal.
- Fine dining
- $60+ per person for upscale restaurants.
- Coffee
- $4-6 for coffee or cappuccino.
Tipping culture
Tip 18-20% in restaurants, $1-2 per drink at bars, and 10-15% for taxis. Cafes often have tip screens; small tips are appreciated but optional.
Plan your visit to Charleston, SC
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Charleston, SC.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Charleston, SC, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like the historic district and popular tourist spots. Beware of overly aggressive street vendors and unofficial taxi services that may overcharge. Additionally, travelers should avoid leaving valuables unattended and be cautious when using ride-sharing apps to ensure the driver matches the booking details. Staying aware of surroundings and using authorized services helps minimize safety risks.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
FAQs: Bus from Frederick, MD to Charleston, SC
Find answers to the most common questions about traveling from Frederick, MD to Charleston, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Charleston, SC, this guide helps you travel smarter and with confidence.
Yes, you can take a bus between Frederick, MD and Charleston, SC.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
popular bus stations
Popular bus stations from Frederick, MD to Charleston, SC
Most Frederick, MD to Charleston, SC buses use the Frederick, East Street (Transit Center) to Charleston, Gaynor Avenue (Greyhound Bus Station) station pair. Use this guide to compare Frederick, MD and Charleston, SC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Frederick
Arrival bus stations in Charleston
Which Frederick, MD station do buses to Charleston, SC leave from?
Buses from Frederick, MD to Charleston, SC leave from Frederick, East Street (Transit Center). The station is 0 miles (1 km) from Frederick, MD city centre at Frederick, MD, USA.
Frederick, East Street (Transit Center)Frederick, MD, USA
City-centre transport
Getting to Frederick, East Street (Transit Center) from Frederick city centre
TrainSouthwest Chief · 63h 13m · $941
Southwest Chief · 67h 1m · $1,150
BusGreyhound US1210 · 63h 11m · $625
Frederick, East Street (Transit Center) bus station facilities and services
Frederick, East Street (Transit Center) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Frederick, East Street (Transit Center). ATMs are available at Frederick, East Street (Transit Center).
Tickets and information
Ticket office support is available at Frederick, East Street (Transit Center).
Parking, taxis and toilets
Available at Frederick, East Street (Transit Center): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Frederick, East Street (Transit Center): Wheelchair accessible entry and exit points.
Which Charleston, SC station do buses from Frederick, MD arrive at?
Buses from Frederick, MD to Charleston, SC arrive at Charleston, Gaynor Avenue (Greyhound Bus Station). Charleston, Gaynor Avenue (Greyhound Bus Station) is 8 miles (13 km) from Charleston, SC city centre.
Charleston, Gaynor Avenue (Greyhound Bus Station)4565 Gaynor Ave, Charleston, SC 29405, USA
City-centre transport
Getting to Charleston, Gaynor Avenue (Greyhound Bus Station) from Charleston city centre
Charleston, Gaynor Avenue (Greyhound Bus Station) is 12 km from Charleston city centre. Public transport options include:
Bus10 · 32m · every ~4 min
10 · 41m · every ~4 min
Charleston, Gaynor Avenue (Greyhound Bus Station) bus station facilities and services
Charleston, Gaynor Avenue (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Free Wi-Fi available. ATMs are available at Charleston, Gaynor Avenue (Greyhound Bus Station).
Tickets and information
Ticket office support is available at Charleston, Gaynor Avenue (Greyhound Bus Station).
Parking, taxis and toilets
Available at Charleston, Gaynor Avenue (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Charleston, Gaynor Avenue (Greyhound Bus Station): Wheelchair accessible.
Bus stations for Frederick, MD to Charleston, SC
Check bus stations information for Frederick, MD and Charleston, SC, including where buses depart and arrive on this route.
Passengers board the bus most frequently from Frederick, East Street (Transit Center), which is located around 0 miles (1 km) away from the city centre, and they get off the bus at Charleston, Gaynor Avenue (Greyhound Bus Station), located 13 away from the city centre.
More options for your journey from Frederick, MD to Charleston, SC
Here are some other resources that might have the information you need
Most popular buses to and from Charleston, SC and Frederick, MD
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