The cheapest and fastest buses from Frederick, MD to Pittsburgh, PA
Cheapest price
$49
Average price
$98
Fastest journey
3 h 30 m
Average duration
3 h 45 m
Buses per day
2
Distance
248 km
The best way to find a cheap bus ticket from Frederick, MD to Pittsburgh, PA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Frederick, MD to Pittsburgh, PA will cost around $98 if you buy it on the day, but the cheapest tickets can be found for only $49.
Of the 2 buses that leave Frederick, MD for Pittsburgh, PA on Sun, Mar 15, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Mar 15 the direct buses cover the 248 km distance in an average of 3 h 45 m but if you time it right, some buses will get you there in just 3 h 30 m .
On Sun, Mar 15 the slowest buses will take 4 h and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Travel Information
Compare train, bus, and flight for Frederick, MD to Pittsburgh, PA
Omio recommends booking the bus as it is the most popular option from Frederick, MD to Pittsburgh, PA among Omio's users. If you are prioritising price take the bus with prices starting from $41. For those with little time consider booking a bus which can get you there in 3h 41m. The ticket price range depends on the travel mode: a bus costs an average of $41, and a flight costs an average of $228.
Distance: 154 miles (248 km)
Compare bus with
Most popular Bus | Train | Flight |
|---|---|---|
$57 Average price Cheapest | $246 Average price | $306 Average price |
4h 11m Average total duration Fastest 3h 41m Onboard + 30m Additional time* | 12h 40m Average total duration 12h 10m Onboard + 30m Additional time* | 9h 52m Average total duration 6h 52m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
Frederick, MD to Pittsburgh, PA bus times
The table below shows live departures for Frederick, MD to Pittsburgh, PA buses for tomorrow, Saturday, March 14. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 12:35 AM Frederick, MD | 4h00 | 4:35 AM Pittsburgh, PA | 0 transfersDirect | |
![]() | 11:45 AM Frederick, MD | 3h30 | 3:15 PM Pittsburgh, PA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Frederick, MD to Pittsburgh, PA by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 15
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Mar 21
Why should you book Frederick, MD to Pittsburgh, PA buses with Omio?
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Frederick, MD to Pittsburgh, PA.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Frederick, MD to Pittsburgh, PA.
Journey information
Overview: Bus from Frederick, MD to Pittsburgh, PA
Buses from Frederick, MD to Pittsburgh, PA run on average 2 times per day, taking around 3h 41m. Cheap bus tickets for this journey start at $41 (€34) if you book in advance.
There are 2 buses per day. The earliest bus runs at 00:30, the last at 23:10. The fastest bus covers the 154 miles (248 km) distance in 3h 30m.
Distance 154 miles (248 km) |
Average bus duration 3h 41m |
Cheapest ticket price $41 (€34) |
Buses per day 2 |
Direct buses 2 |
Fastest bus 3h 30m |
First bus 00:30 |
Last bus 23:10 |
Bus providers: Greyhound from Frederick, MD to Pittsburgh, PAYou can travel by bus between Frederick, MD to Pittsburgh, PA with Greyhound for as low as $41 (€34). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from Frederick, MD to Pittsburgh, PA
Find answers to the most common questions about traveling from Frederick, MD to Pittsburgh, PA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Pittsburgh, PA, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- The Andy Warhol Museum, a comprehensive collection dedicated to the life and works of the iconic pop artist
- Phipps Conservatory and Botanical Gardens, a historic greenhouse with diverse plant exhibits and sustainable architecture
- Carnegie Museum of Natural History, featuring extensive dinosaur displays and global cultural artifacts
- Point State Park, a scenic urban park at the confluence of three rivers with historical significance
- Mount Washington, offering panoramic views of Pittsburgh's skyline from its renowned overlooks.
- Heinz History Center, an affiliate of the Smithsonian Institution showcasing Western Pennsylvania's history and heritage
- Take a ride on the Duquesne Incline for a historic cable car experience and stunning city views
- Explore the Strip District, known for its vibrant markets, eateries, and unique shops
- Visit the National Aviary, home to a diverse collection of birds from around the world
- Enjoy a Pittsburgh Pirates game at PNC Park, renowned for its beautiful views of the city skyline.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Frederick, MD to Pittsburgh, PA
Most popular bus connections from Frederick, MD
More options for your journey from Frederick, MD to Pittsburgh, PA
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