- Must visit
Philadelphia Museum of Art
World-class art museum famous for major collections and the Rocky Steps. A top cultural stop with strong city views.
Buses from Frederick, MD to Philadelphia, PA run on average 4 times per day, taking around 4h 38m. Cheap bus tickets for this journey start at $45 (€38) if you book in advance.
The earliest bus runs at 00:30, the last at 23:15. The fastest bus covers the 124 miles (201 km) distance in 4h 0m.
Distance 124 miles (201 km) |
Average bus duration 4h 38m |
Cheapest ticket price $45 (€38) |
Buses per day 4 |
Fastest bus 4h 0m |
First bus 12:30 AM |
Last bus 11:15 PM |
Cheapest Month Dec |
Cheapest Day Thu |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Thu |
Least Busy Day Thu |
Best time to book 4 days |
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Frederick, MD to Philadelphia, PA.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 04:35AM | Arrival Time 10:45AM | Duration 6h10 | Departure days Fri | Cheapest price $73 |
Operator Greyhound | Departure Time 09:05AM | Arrival Time 07:05PM | Duration 10h00 | Departure days Wed, Fri | Cheapest price $59 |
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Philadelphia, PA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Philadelphia, PA trip today.
World-class art museum famous for major collections and the Rocky Steps. A top cultural stop with strong city views.
Hands-on science museum for all ages, known for interactive exhibits and the giant walk-through heart near the Parkway.
Celebrated collection of Impressionist, Post-Impressionist, and modern works in an intimate gallery setting on the Parkway.
Historic district packed with foundational sites, cobblestone streets, and museums. The best base for first-time visitors.
Beloved park atop a hill with skyline views, trails, and the Rocky Steps approach. Great for walking and photography.
Walkable district of rowhouses, boutiques, and small parks. A classic local neighborhood for architecture and relaxed city strolling.
A long roll packed with thin-sliced beef and melted cheese, often with fried onions. It is Philadelphia's signature street and comfort food.
A soft pretzel with a distinct figure-eight twist and chewy texture. Sold by street vendors and bakeries, it is a classic Philadelphia snack.
A roast pork sandwich with garlicky pork, sharp provolone, and broccoli rabe. Many locals consider it the city's best traditional sandwich.
Acclaimed fine dining restaurant by Chef Marc Vetri, known for refined Italian tasting menus and one of Philadelphia's top culinary experiences.
Historic roast pork and cheesesteak shop in South Philadelphia, known for hearty sandwiches and a no-frills local atmosphere.
Beloved local chain specializing in water ice and frozen custard. It is a go-to stop for a classic Philadelphia summer dessert.
Moderate for a major US city. Hotels can be pricey in Center City, but dining and transit are often cheaper than New York or Washington.
Tip 18-20% in restaurants, 15-20% for taxis, and $1-2 per drink or cafe order if service is provided.
Official public transport app
Philadelphia Bus Terminal -> Philadelphia City Hall, Philadelphia, PA
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Philadelphia, PA.
Find answers to the most common questions about traveling from Frederick, MD to Philadelphia, PA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Philadelphia, PA, this guide helps you travel smarter and with confidence.

Most Frederick, MD to Philadelphia, PA buses use the Frederick, East Street (Transit Center) to Philadelphia, Greyhound Bus Station station pair, with some services arriving at Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park). Use this guide to compare Frederick, MD and Philadelphia, PA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Frederick, East Street (Transit Center) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Frederick, East Street (Transit Center). ATMs are available at Frederick, East Street (Transit Center).
Ticket office support is available at Frederick, East Street (Transit Center).
Available at Frederick, East Street (Transit Center): Parking, Taxis, WC.
Accessibility facilities are available at Frederick, East Street (Transit Center): Wheelchair accessible entry and exit points.
Philadelphia, Greyhound Bus Station has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Snack bars and vending machines are available.
Free Wi-Fi available in the waiting area. ATMs are an ATM is available near the entrance.
Ticket office support is available at Philadelphia, Greyhound Bus Station.
Available at Philadelphia, Greyhound Bus Station: Parking, Taxis, WC.
Accessibility facilities are available at Philadelphia, Greyhound Bus Station: The station is wheelchair accessible with ramps and elevators.
Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park) is 2 km from Philadelphia city centre. Public transport options include:
Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park). ATMs are available at Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park).
Ticket office support is available at Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park).
Available at Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park): Parking, Taxis, WC.
Accessibility facilities are available at Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park): The bus stop is accessible with ramps.
Check bus stations information for Frederick, MD and Philadelphia, PA, including where buses depart and arrive on this route.
Here are some other resources that might have the information you need