- Must visit
Philadelphia Museum of Art
World-class art museum famous for major collections and the Rocky Steps. A top cultural stop with strong city views.
Omio recommends booking the bus as it is the most popular option from Frederick, MD to Philadelphia, PA among Omio's users. If you are prioritising price take the bus with prices starting from $60. For those with little time consider booking a train which can get you there in 2h 48m. The ticket price range depends on the travel mode: a bus costs an average of $60, and a flight costs an average of $401.
Distance: 124 miles (201 km)
Most popular Bus | Train | Flight | Driving |
|---|---|---|---|
$71 Average price Cheapest | $185 Average price | $475 Average price | $30 Average price (fuel + tolls) |
5h 32m Average total duration 5h 2m Onboard + 30m Additional time* | 3h 18m Average total duration Fastest 2h 48m Onboard + 30m Additional time* | 7h 9m Average total duration 4h 9m Onboard + 3h 0m Additional time* | 2h 30m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Frederick, MD to Philadelphia, PA:
A bus is $115 (€95) less than a train for this route with tickets for a train from Frederick, MD to Philadelphia, PA costing on average $185 (€153).
A bus is $405 (€334) less than a flight for this route with tickets for a flight from Frederick, MD to Philadelphia, PA costing on average $475 (€392).
Other travel options to Philadelphia, PA take longer:
Flight takes on average 4h 9m.
Bus takes on average 5h 2m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 04:35AM | Arrival Time 10:45AM | Duration 6h10 | Departure days Fri | Cheapest price $75 |
Operator Greyhound | Departure Time 05:25AM | Arrival Time 10:45AM | Duration 5h20 | Departure days Tue, Wed, Sat | Cheapest price $44 |
Operator Greyhound | Departure Time 09:05AM | Arrival Time 07:05PM | Duration 10h00 | Departure days Fri | Cheapest price $73 |
Operator Greyhound | Departure Time 10:25AM | Arrival Time 03:45PM | Duration 5h20 | Departure days Tue, Wed, Sat | Cheapest price $44 |
Operator Greyhound | Departure Time 11:40PM | Arrival Time 06:45AM | Duration 7h05 | Departure days Tue, Wed, Sat | Cheapest price $47 |
The table below shows live departures for Frederick, MD to Philadelphia, PA buses for today, Wednesday, July 29. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
· | 11:40 PM Frederick, East Street (Transit Center) | 7h05 | 6:45 AM Philadelphia Bus Station | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Frederick, MD to Philadelphia, PA run on average 10 times per day, taking around 5h 2m. Cheap bus tickets for this journey start at $60 (€49) if you book in advance.
The earliest bus runs at 00:30, the last at 23:15. The fastest bus covers the 124 miles (201 km) distance in 5h 20m.
Distance 124 miles (201 km) |
Average bus duration 5h 2m |
Cheapest ticket price $60 (€49) |
Buses per day 10 |
Fastest bus 5h 20m |
First bus 12:30 AM |
Last bus 11:15 PM |
Cheapest Month Jul |
Cheapest Day Tue |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Tue |
Least Busy Day Tue |
Best time to book 28 days |
Discover the best of Philadelphia, PA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Philadelphia, PA trip today.
World-class art museum famous for major collections and the Rocky Steps. A top cultural stop with strong city views.
Hands-on science museum for all ages, known for interactive exhibits and the giant walk-through heart near the Parkway.
Celebrated collection of Impressionist, Post-Impressionist, and modern works in an intimate gallery setting on the Parkway.
Historic district packed with foundational sites, cobblestone streets, and museums. The best base for first-time visitors.
Beloved park atop a hill with skyline views, trails, and the Rocky Steps approach. Great for walking and photography.
Walkable district of rowhouses, boutiques, and small parks. A classic local neighborhood for architecture and relaxed city strolling.
A long roll packed with thin-sliced beef and melted cheese, often with fried onions. It is Philadelphia's signature street and comfort food.
A soft pretzel with a distinct figure-eight twist and chewy texture. Sold by street vendors and bakeries, it is a classic Philadelphia snack.
A roast pork sandwich with garlicky pork, sharp provolone, and broccoli rabe. Many locals consider it the city's best traditional sandwich.
Acclaimed fine dining restaurant by Chef Marc Vetri, known for refined Italian tasting menus and one of Philadelphia's top culinary experiences.
Historic roast pork and cheesesteak shop in South Philadelphia, known for hearty sandwiches and a no-frills local atmosphere.
Beloved local chain specializing in water ice and frozen custard. It is a go-to stop for a classic Philadelphia summer dessert.
Moderate for a major US city. Hotels can be pricey in Center City, but dining and transit are often cheaper than New York or Washington.
Tip 18-20% in restaurants, 15-20% for taxis, and $1-2 per drink or cafe order if service is provided.
Official public transport app
Philadelphia Bus Terminal -> Philadelphia City Hall, Philadelphia, PA
Find answers to the most common questions about traveling from Frederick, MD to Philadelphia, PA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Philadelphia, PA, this guide helps you travel smarter and with confidence.

Most Frederick, MD to Philadelphia, PA buses use the Frederick, East Street (Transit Center) to Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park) station pair, with some services arriving at Philadelphia, Greyhound Bus Station. Use this guide to compare Frederick, MD and Philadelphia, PA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
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