The cheapest and fastest buses from Frederick, MD to Chicago, IL
Cheapest price
€218
Average price
€254
Fastest journey
14 h 50 m
Average duration
17 h 13 m
Buses per day
2
Distance
905 km
The best way to find a cheap bus ticket from Frederick, MD to Chicago, IL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Frederick, MD to Chicago, IL will cost around €254 if you buy it on the day, but the cheapest tickets can be found for only €218.
Of the 2 buses that leave Frederick, MD for Chicago, IL on Tue, Dec 09, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Tue, Dec 09 the direct buses cover the 905 km distance in an average of 17 h 13 m but if you time it right, some buses will get you there in just 14 h 50 m .
On Tue, Dec 09 the slowest buses will take 19 h 35 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Travel Information
Compare train, bus, and flight for Frederick, MD to Chicago, IL
Omio recommends booking the bus as it is the most popular option from Frederick, MD to Chicago, IL among Omio's users. If you are prioritising price take the bus with prices starting from €64. For those with little time consider booking a flight which can get you there in 7h 49m. The ticket price range depends on the travel mode: a bus costs an average of €64, and a flight costs an average of €105.
Distance: 562 miles (905 km)
Compare bus with
Most popular Bus | Flight | Train |
|---|---|---|
€83 Average price Cheapest | €186 Average price | €142 Average price |
16h 20m Average total duration 15h 50m Onboard + 30m Additional time* | 10h 49m Average total duration Fastest 7h 49m Onboard + 3h 0m Additional time* | 18h 6m Average total duration 17h 36m Onboard + 30m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
Frederick, MD to Chicago, IL bus times
The table below shows live departures for Frederick, MD to Chicago, IL buses for today, Monday, December 8. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 12:50 PM Frederick, MD | 15h50 | 4:40 AM Chicago, IL | 0 transfersDirect | |
| Tuesday, December 9 | |||||
![]() | 12:30 AM Frederick, MD | 19h35 | 8:05 PM Chicago, IL | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Frederick, MD to Chicago, IL by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Dec 09
Dec 10
Dec 11
Dec 12
Dec 13
Dec 14
Dec 15
Journey information
Overview: Bus from Frederick, MD to Chicago, IL
Buses from Frederick, MD to Chicago, IL run on average 2 times per day, taking around 15h 50m. Cheap bus tickets for this journey start at $80 (€64) if you book in advance.
There are 1 buses per day. The earliest bus runs at 06:55, the last at 23:15. The fastest bus covers the 562 miles (905 km) distance in 15h 25m.
Distance 562 miles (905 km) |
Average bus duration 15h 50m |
Cheapest ticket price $80 (€64) |
Buses per day 2 |
Direct buses 1 |
Fastest bus 15h 25m |
First bus 06:55 |
Last bus 23:15 |
Bus providers: Greyhound from Frederick, MD to Chicago, ILYou can travel by bus between Frederick, MD to Chicago, IL with Greyhound for as low as $80 (€64). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from Frederick, MD to Chicago, IL
Find answers to the most common questions about traveling from Frederick, MD to Chicago, IL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Chicago, IL, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Millennium Park, a public park known for its modern art installations and the iconic Cloud Gate sculpture
- Art Institute of Chicago, a renowned museum housing an extensive collection of art from around the world
- Navy Pier, a popular entertainment destination featuring rides, restaurants, and lakefront views
- Willis Tower Skydeck, an observation deck offering panoramic views of the city from one of the tallest buildings in the Western Hemisphere
- Field Museum, a natural history museum with vast exhibits including the famous T. Rex skeleton, Sue.
- Museum of Science and Industry, an interactive museum featuring exhibits on science, technology, and industry
- Explore the vibrant neighborhoods of Chicago, such as Wicker Park and Lincoln Park, known for their unique shops and eateries
- Take a river cruise to see the city's iconic architecture from a different perspective
- Attend a live performance at the historic Chicago Theatre
- Enjoy a day at Lincoln Park Zoo, one of the oldest zoos in the U. S. Offering free admission.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
To find the cheapest bus tickets for your trip from Frederick, MD to Chicago, IL, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Frederick, MD to Chicago, IL
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