Frederick, MD to Boston, MA bus with FlixBus

Mon, Sep 14
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Greyhound
FlixBus
Alsa
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Rede Expressos
2,000+ travel companies
Greyhound
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
2,000+ travel companies
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Travel Information

Compare bus, train, and flight for Frederick, MD to Boston, MA

Omio recommends booking the bus as it is the most popular option from Frederick, MD to Boston, MA among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $102 For those with little time, consider booking a flight, which has an average total journey time of 5h 36m. Average ticket prices depend on the travel mode: a bus costs an average of $102, while a flight costs an average of $508.

Distance: 388 miles (626 km)

Compare bus with

Most popular
Bus
Train
Flight
Driving

$102

Average price

Cheapest

$508

Average price

$92

Average price

(fuel + tolls)

11h 18m

Average total duration

10h 48m

Onboard

+

30m

Additional time*

5h 36m

Average total duration

Fastest

3h 36m

Onboard

+

2h 0m

Additional time*

7h 39m

Average total duration

(door-to-door)

Direct Options

Direct Options

Direct Options

Direct Options

The cheapest way to travel from Frederick, MD to Boston, MA is a bus with an average price of $102.

This is compared to other travel options from Frederick, MD to Boston, MA:

A bus is $406 less than a flight for this route with tickets for a flight from Frederick, MD to Boston, MA costing on average $508.

The fastest way to travel from Frederick, MD to Boston, MA is by flight with an average journey time of 3h 36m.

Other travel options to Boston, MA take longer:

Bus takes on average 10h 48m.

It's helpful to compare your options as there are 3 ways to travel between Frederick, MD and Boston, MA including taking a bus, train, and flight.
We recommend using the bus as it is the most popular way to get from Frederick, MD to Boston, MA among Omio's users.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.

Tickets start at around $102 compared to roughly $92 in fuel and tolls — a saving of about $-10.39. The journey takes 10h 48m versus 7h 39m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.

Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.

Frederick, MD to Boston, MA Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
Greyhound
Departure Time
09:05AM
Arrival Time
10:50PM
Duration
13h45
Departure days
Fri
Cheapest price
$64
Operator
FlixBus
Departure Time
02:25PM
Arrival Time
03:30AM
Duration
13h05
Departure days
Thu
Cheapest price
$141
Operator
FlixBus
Departure Time
03:25PM
Arrival Time
04:50AM
Duration
13h25
Departure days
Wed
Cheapest price
$169

Compare prices and tickets Frederick, MD to Boston, MA by bus, train, or flight

Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Mon
Sep 14
Tue
Sep 15
Wed
Sep 16
Thu
Sep 17
Fri
Sep 18
Sat
Sep 19
Sun
Sep 20

Why should you book Frederick, MD to Boston, MA buses with Omio?

Greyhound operates all buses services from Frederick, MD to Boston, MA.
Omio is an official ticket reseller for all your travel options from Frederick, MD to Boston, MA.

Why book with Omio vs Greyhound?

  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Frederick, MD to Boston, MA.

Why book with Omio over Wanderu?

  • Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Frederick, MD to Boston, MA.

Journey information

Overview: Bus from Frederick, MD to Boston, MA

USAUSA
USAUSA
Icon of bus

Buses from Frederick, MD to Boston, MA run on average 3 times per day, taking around 10h 48m. Cheap bus tickets for this journey start at $79 if you book in advance.

The earliest bus runs at 01:05, the last at 21:50. The fastest bus covers the 388 miles (626 km) distance in 10h 5m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
388 miles (626 km)
Average bus duration
10h 48m
Cheapest ticket price
$79
Buses per day
3
Fastest bus
10h 5m
First bus
1:05 AM
Last bus
9:50 PM
Cheapest Month
Apr
Cheapest Day
Fri
High Season
Jul - Sep
Low Season
Oct - Dec
Busiest Day
Sat
Least Busy Day
Sat
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: FlixBus, Greyhound from Frederick, MD to Boston, MAYou can travel by bus between Frederick, MD to Boston, MA with FlixBus, Greyhound for as low as $79. When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
10h 5m
Cheapest FlixBus Price
$81
FlixBus frequency
1 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
10h 30m
Cheapest Greyhound Price
$79
Greyhound frequency
2 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.

Complete guide to Boston, MA

Things to do in Boston, MA

Discover the best of Boston, MA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Boston, MA trip today.

  • Must visit

Museum of Fine Arts, Boston

Major art museum with encyclopedic collections, from ancient works to Impressionism, in a grand and highly walkable campus.

  • Must visit

Isabella Stewart Gardner Museum

Unique museum displaying Isabella Stewart Gardner's art collection in a Venetian-style palace with a beautiful courtyard.

  • Must visit

Museum of Science

Hands-on science museum on the Charles River, popular for interactive exhibits, live presentations, and family-friendly learning.

US dollar ($)

Boston is pricier than many US cities. Hotels, dining, and attractions add up fast, though transit is manageable and budget food options exist.

Average meal costs

Budget
$10-18 for fast food or casual takeout.
Mid-range
$25-45 per person for a mid-range restaurant meal.
Fine dining
$75+ per person for upscale dining.
Coffee
$3-6 for drip coffee or cappuccino.

Tipping culture

Tip 18-20% at restaurants, more for excellent service. Taxis: 10-15%. Cafes: round up or add $1 per drink.

FAQs: Bus from Frederick, MD to Boston, MA

Find answers to the most common questions about traveling from Frederick, MD to Boston, MA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Boston, MA, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Frederick, MD to Boston, MA can start from as little as $79 when you book in advance. The average bus ticket price for Frederick, MD to Boston, MA is $102 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Frederick, MD to Boston, MA is 10h 5m to travel the 388 miles (626 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Frederick, MD to Boston, MA leaves at 1:05 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Frederick, MD to Boston, MA leaves at 9:50 PM.
There are 3 buses a day from Frederick, MD to Boston, MA which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Frederick, MD to Boston, MA, you can count on Greyhound for the best way to get you to Boston, MA. You can also check all possible bus companies who offer a service between Frederick, MD and Boston, MA and compare the amenities they offer before buying a bus ticket.
Passengers board the bus most frequently from Frederick, East Street (Transit Center), which is located around away from the city centre, and they get off the bus at Boston, Bus Terminal South Station, located 0 away from the city centre.
A trip to Boston, MA from Frederick, MD is worth doing but not as a day trip with a journey time of 10h 5m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Frederick, MD to Boston, MA is April.
It's helpful to compare your options as there are 3 ways to travel between Frederick, MD and Boston, MA including taking a bus, train, and flight.
Yes, the following accessibility options are available when taking the bus from Frederick, MD to Boston, MA:
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Frederick, MD to Boston, MA for bus company Greyhound.
Some of the most interesting sights to explore in Boston, MA are:
  • Best sights: Freedom Trail, a 2.5-mile-long path through downtown Boston that passes by 16 significant historical sites
  • Fenway Park, the iconic baseball stadium and home of the Boston Red Sox
  • Museum of Fine Arts, one of the largest art museums in the United States with an extensive collection of artworks
  • Boston Common, the oldest public park in the United States offering green space and historical landmarks
  • New England Aquarium, a popular attraction featuring a wide variety of marine life and interactive exhibits.
The best things to do in Boston, MA include:
  • Things to do: Explore the historic streets of Beacon Hill, known for its charming cobblestone streets and Federal-style rowhouses
  • Take a scenic walk along the Charles River Esplanade, offering beautiful views of the Boston skyline
  • Visit the Boston Public Library, a stunning architectural landmark with impressive collections and exhibits
  • Enjoy a guided tour of the historic USS Constitution, the world's oldest commissioned naval vessel still afloat
  • Discover the vibrant atmosphere of Quincy Market, with its diverse food stalls and unique shops.
Whether you can cancel your bus ticket from Frederick, MD to Boston, MA depends on the bus companies:
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Frederick, MD to Boston, MA.
Yes, the following luggage options are included when booking a bus ticket from Frederick, MD to Boston, MA:
  • Greyhound
    • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Frederick, MD to Boston, MA:
  • Greyhound
    • $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Frederick, MD to Boston, MA.
You can reserve your seat on the bus from Frederick, MD to Boston, MA with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Frederick, MD to Boston, MA with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Frederick, MD to Boston, MA with the following bus company: Greyhound.
Since neither Frederick, MD nor Boston, MA are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the bus as it is the most popular way to get from Frederick, MD to Boston, MA among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Boston, MA, travelers should be aware of pickpocketing and bag theft, especially in crowded areas like public transit and popular tourist spots. Common scams include fake charity solicitations and overcharging by unlicensed taxi drivers. It's advisable to use official transportation services, stay alert in busy areas, and avoid sharing personal information with strangers to ensure safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from Frederick, MD to Boston, MA

Most Frederick, MD to Boston, MA buses use the Frederick, East Street (Transit Center) to Boston, Bus Terminal South Station station pair. Use this guide to compare Frederick, MD and Boston, MA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.

Departure bus stations in Frederick
Arrival bus stations in Boston

Which Frederick, MD station do buses to Boston, MA leave from?

Buses from Frederick, MD to Boston, MA leave from Frederick, East Street (Transit Center). The station is 0 miles (1 km) from Frederick, MD city centre at Frederick, MD, USA.
Frederick, East Street (Transit Center)Frederick, MD, USAWifiParkingATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to Frederick, East Street (Transit Center) from Frederick city centre

TrainSouthwest Chief · 63h 13m · $981
Southwest Chief · 67h 1m · $1199
BusGreyhound US1210 · 63h 11m · $651

Frederick, East Street (Transit Center) bus station facilities and services

Frederick, East Street (Transit Center) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Wi-Fi and ATMs

Wi-Fi is available at Frederick, East Street (Transit Center). ATMs are available at Frederick, East Street (Transit Center).

Tickets and information

Ticket office support is available at Frederick, East Street (Transit Center).

Parking, taxis and toilets

Available at Frederick, East Street (Transit Center): Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at Frederick, East Street (Transit Center): Wheelchair accessible entry and exit points.

More options for your journey from Frederick, MD to Boston, MA

Here are some other resources that might have the information you need

HomeBusesBuses in USABus tickets to Boston, MAFrederick, MD to Boston, MA bus

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