The cheapest and fastest buses from Frederick, MD to Boston, MA
Cheapest price
€88
Average price
€88
Fastest journey
20 h 10 m
Average duration
20 h 10 m
Buses per day
1
Distance
626 km
The best way to find a cheap bus ticket from Frederick, MD to Boston, MA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Frederick, MD to Boston, MA will cost around €88 if you buy it on the day, but the cheapest tickets can be found for only €88.
Of the 1 buses that leave Frederick, MD for Boston, MA on Tue, Dec 09, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Tue, Dec 09 the direct buses cover the 626 km distance in an average of 20 h 10 m but if you time it right, some buses will get you there in just 20 h 10 m .
On Tue, Dec 09 the slowest buses will take 20 h 10 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Travel Information
Compare bus, train, and flight for Frederick, MD to Boston, MA
Omio recommends booking the bus as it is the most popular option from Frederick, MD to Boston, MA among Omio's users. If you are prioritising price take the bus with prices starting from €45. For those with little time consider booking a flight which can get you there in 3h 54m. The ticket price range depends on the travel mode: a bus costs an average of €45, and a train costs an average of €174.
Distance: 388 miles (626 km)
Compare bus with
Most popular Bus | Flight | Train |
|---|---|---|
€78 Average price Cheapest | €124 Average price | €197 Average price |
18h 30m Average total duration 18h 0m Onboard + 30m Additional time* | 6h 54m Average total duration Fastest 3h 54m Onboard + 3h 0m Additional time* | 16h 15m Average total duration 15h 45m Onboard + 30m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
Frederick, MD to Boston, MA bus times
The table below shows live departures for Frederick, MD to Boston, MA buses for today, Monday, December 8. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 7:30 PM Frederick, MD | 9h40 | 5:10 AM Boston, MA | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Frederick, MD to Boston, MA by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Dec 09
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Dec 15
Journey information
Overview: Bus from Frederick, MD to Boston, MA
Buses from Frederick, MD to Boston, MA run on average 7 times per day, taking around 18h 0m. Cheap bus tickets for this journey start at $56 (€45) if you book in advance.
The earliest bus runs at 06:30, the last at 19:45. The fastest bus covers the 388 miles (626 km) distance in 11h 30m.
Distance 388 miles (626 km) |
Average bus duration 18h 0m |
Cheapest ticket price $56 (€45) |
Buses per day 7 |
Fastest bus 11h 30m |
First bus 06:30 |
Last bus 19:45 |
Bus providers: Greyhound, BayRunner Shuttle from Frederick, MD to Boston, MAYou can travel by bus between Frederick, MD to Boston, MA with Greyhound, BayRunner Shuttle for as low as $56 (€45). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
BayRunner Shuttle
FAQs: Bus from Frederick, MD to Boston, MA
Find answers to the most common questions about traveling from Frederick, MD to Boston, MA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Boston, MA, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Best sights: Freedom Trail, a 2.5-mile-long path through downtown Boston that passes by 16 significant historical sites
- Fenway Park, the iconic baseball stadium and home of the Boston Red Sox
- Museum of Fine Arts, one of the largest art museums in the United States with an extensive collection of artworks
- Boston Common, the oldest public park in the United States offering green space and historical landmarks
- New England Aquarium, a popular attraction featuring a wide variety of marine life and interactive exhibits.
- Things to do: Explore the historic streets of Beacon Hill, known for its charming cobblestone streets and Federal-style rowhouses
- Take a scenic walk along the Charles River Esplanade, offering beautiful views of the Boston skyline
- Visit the Boston Public Library, a stunning architectural landmark with impressive collections and exhibits
- Enjoy a guided tour of the historic USS Constitution, the world's oldest commissioned naval vessel still afloat
- Discover the vibrant atmosphere of Quincy Market, with its diverse food stalls and unique shops.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
To find the cheapest bus tickets for your trip from Frederick, MD to Boston, MA, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Frederick, MD to Boston, MA
Most popular bus connections from Frederick, MD
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