- Must visit
Museum of Fine Arts, Boston
Major art museum with encyclopedic collections, from ancient works to Impressionism, in a grand and highly walkable campus.
Cheapest price
$138
Average price
$138
Fastest journey
13 h 5 m
Average duration
13 h 5 m
Buses per day
1
Distance
626 km
The best way to find a cheap bus ticket from Frederick, MD to Boston, MA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Frederick, MD to Boston, MA will cost around $138 if you buy it on the day, but the cheapest tickets can be found for only $138.
Of the 1 buses that leave Frederick, MD for Boston, MA on Thu, Jul 30, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Jul 30 the direct buses cover the 626 km distance in an average of 13 h 5 m but if you time it right, some buses will get you there in just 13 h 5 m .
On Thu, Jul 30 the slowest buses will take 13 h 5 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Omio recommends booking the bus as it is the most popular option from Frederick, MD to Boston, MA among Omio's users. If you are prioritising price take the bus with prices starting from $62. For those with little time consider booking a flight which can get you there in 1h 29m. The ticket price range depends on the travel mode: a bus costs an average of $62, and a train costs an average of $173.
Distance: 388 miles (626 km)
Most popular Bus | Train | Flight | Driving |
|---|---|---|---|
$122 Average price Cheapest | $279 Average price | $137 Average price | $89 Average price (fuel + tolls) |
13h 30m Average total duration 13h 0m Onboard + 30m Additional time* | 12h 51m Average total duration 12h 21m Onboard + 30m Additional time* | 4h 29m Average total duration Fastest 1h 29m Onboard + 3h 0m Additional time* | 7h 39m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Frederick, MD to Boston, MA:
A bus is $15 (€12) less than a flight for this route with tickets for a flight from Frederick, MD to Boston, MA costing on average $137 (€113).
A bus is $157 (€129) less than a train for this route with tickets for a train from Frederick, MD to Boston, MA costing on average $279 (€230).
Other travel options to Boston, MA take longer:
Train takes on average 12h 21m.
Bus takes on average 13h 0m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 05:25AM | Arrival Time 06:50PM | Duration 13h25 | Departure days Mon | Cheapest price $103 |
Operator Greyhound | Departure Time 09:05AM | Arrival Time 10:50PM | Duration 13h45 | Departure days Fri | Cheapest price $62 |
Operator FlixBus | Departure Time 10:25AM | Arrival Time 11:30PM | Duration 13h05 | Departure days Mon | Cheapest price $92 |
Operator FlixBus | Departure Time 02:25PM | Arrival Time 03:30AM | Duration 13h05 | Departure days Thu | Cheapest price $138 |
Operator FlixBus | Departure Time 03:25PM | Arrival Time 04:50AM | Duration 13h25 | Departure days Wed | Cheapest price $166 |
Operator FlixBus | Departure Time 11:40PM | Arrival Time 12:00PM | Duration 12h20 | Departure days Mon | Cheapest price $99 |
The table below shows live departures for Frederick, MD to Boston, MA buses for tomorrow, Thursday, July 30. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 2:25 PM Frederick, MD | 13h05 | 3:30 AM Boston, MA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Frederick, MD to Boston, MA run on average 6 times per day, taking around 13h 0m. Cheap bus tickets for this journey start at $62 (€51) if you book in advance.
The earliest bus runs at 01:05, the last at 21:50. The fastest bus covers the 388 miles (626 km) distance in 13h 5m.
Distance 388 miles (626 km) |
Average bus duration 13h 0m |
Cheapest ticket price $62 (€51) |
Buses per day 6 |
Fastest bus 13h 5m |
First bus 1:05 AM |
Last bus 9:50 PM |
Cheapest Month Apr |
Cheapest Day Mon |
High Season Apr - Jun |
Low Season Oct - Dec |
Discover the best of Boston, MA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Boston, MA trip today.
Major art museum with encyclopedic collections, from ancient works to Impressionism, in a grand and highly walkable campus.
Unique museum displaying Isabella Stewart Gardner's art collection in a Venetian-style palace with a beautiful courtyard.
Hands-on science museum on the Charles River, popular for interactive exhibits, live presentations, and family-friendly learning.
Historic brick-lined route connecting key revolutionary sites, ideal for first-time visitors seeking Boston's core story on foot.
Elegant public garden famous for swan boats, seasonal flowers, and postcard views in the heart of downtown Boston.
Historic market district and pedestrian-friendly area known for street life, shops, performers, and easy downtown exploring.
Creamy New England chowder with clams, potatoes, and salt pork. It is a defining Boston seafood dish tied to the city's maritime history.
Hot dog bun split on top and filled with chilled lobster meat, usually with butter or mayo. A classic New England summer seafood staple.
Baked cod topped with buttery crumbs, often with lemon. It reflects Boston's long cod fishing tradition and old-school Yankee cooking.
Elegant fine-dining destination by the waterfront known for pristine seafood, tasting menus, and one of Boston's top culinary reputations.
Classic North End Italian restaurant famous for generous portions, old-school service, and beloved Boston dining tradition.
Refined seafood restaurant and oyster bar with polished service, excellent raw bar options, and a Back Bay setting.
Boston is pricier than many US cities. Hotels, dining, and attractions add up fast, though transit is manageable and budget food options exist.
Tip 18-20% at restaurants, more for excellent service. Taxis: 10-15%. Cafes: round up or add $1 per drink.
Find answers to the most common questions about traveling from Frederick, MD to Boston, MA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Boston, MA, this guide helps you travel smarter and with confidence.

Most Frederick, MD to Boston, MA buses use the Frederick, East Street (Transit Center) to Boston, Bus Terminal South Station station pair. Use this guide to compare Frederick, MD and Boston, MA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need