Frederick, MD to Buffalo, NY bus with Greyhound

Sat, Mar 14
+ Add return
Greyhound
BayRunner Shuttle
FlixBus
Alsa
Costa Verde
1,000+ travel companies
Greyhound
BayRunner Shuttle
FlixBus
Alsa
Costa Verde
1,000+ travel companies
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The cheapest and fastest buses from Frederick, MD to Buffalo, NY

Showing times and prices for Mar 15

Cheapest price

$214

Average price

$242

Fastest journey

14 h 40 m

Average duration

17 h 10 m

Buses per day

2

Distance

405 km

Cheap tickets

The best way to find a cheap bus ticket from Frederick, MD to Buffalo, NY is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Frederick, MD to Buffalo, NY will cost around $242 if you buy it on the day, but the cheapest tickets can be found for only $214.

Fast buses

It's difficult to get from Frederick, MD to Buffalo, NY without transferring at least once.

Greyhound USA
08:50AM14h40
Frederick, MD
11:30PMBuffalo, NY
$2141One-way
1 transfer
Greyhound USA
12:30AM19h40
Frederick, MD
08:10PMBuffalo, NY
$2701One-way
2 transfers

Travel Information

Compare bus and flight for Frederick, MD to Buffalo, NY

Omio recommends booking the bus as it is the most popular option from Frederick, MD to Buffalo, NY among Omio's users. If you are prioritising price take the bus with prices starting from $75. For those with little time consider booking a flight which can get you there in 4h 25m. The ticket price range depends on the travel mode: a bus costs an average of $75, and a flight costs an average of $112.

Distance: 251 miles (405 km)

Compare bus with

Most popular
Bus
Flight

$82

Average price

Cheapest

$112

Average price

16h 50m

Average total duration

16h 20m

Onboard

+

30m

Additional time*

7h 25m

Average total duration

Fastest

4h 25m

Onboard

+

3h 0m

Additional time*

Direct Options

Direct Options

Live departures

Frederick, MD to Buffalo, NY bus times

The table below shows live departures for Frederick, MD to Buffalo, NY buses for tomorrow, Saturday, March 14. You can also manually refresh the results below to see updated bus journeys.

Last updated at 4:24 PM
ProviderDepartsDurationArrivesTransfers
Tickets
greyhound12:30 AM Frederick, MD
19h40
8:10 PM Buffalo, NY2 transfers
greyhound8:50 AM Frederick, MD
14h40
11:30 PM Buffalo, NY1 transfer

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Frederick, MD to Buffalo, NY by bus or flight

Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Sun
Mar 15
Mon
Mar 16
Tue
Mar 17
Wed
Mar 18
Thu
Mar 19
Fri
Mar 20
Sat
Mar 21

Why should you book Frederick, MD to Buffalo, NY buses with Omio?

Greyhound as well as BayRunner Shuttle offer buses services from Frederick, MD to Buffalo, NY.
Omio is an official ticket reseller for all your travel options from Frederick, MD to Buffalo, NY.

Why book with Omio vs Greyhound?

  • Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of BayRunner Shuttle to find the best option for your trip from Frederick, MD to Buffalo, NY.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Frederick, MD to Buffalo, NY.

Why book with Omio over Wanderu?

  • Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Frederick, MD to Buffalo, NY.

Journey information

Overview: Bus from Frederick, MD to Buffalo, NY

USAUSA
USAUSA
Icon of bus

Buses from Frederick, MD to Buffalo, NY run on average 5 times per day, taking around 16h 20m. Cheap bus tickets for this journey start at $75 (€61) if you book in advance.

The earliest bus runs at 00:55, the last at 23:55. The fastest bus covers the 251 miles (405 km) distance in 15h 20m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
251 miles (405 km)
Average bus duration
16h 20m
Cheapest ticket price
$75 (€61)
Buses per day
5
Fastest bus
15h 20m
First bus
00:55
Last bus
23:55
Cheapest month
Sep
Cheapest day
Fri
High season
Oct - Dec
Low season
Apr - Jun
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: Greyhound, BayRunner Shuttle from Frederick, MD to Buffalo, NYYou can travel by bus between Frederick, MD to Buffalo, NY with Greyhound, BayRunner Shuttle for as low as $75 (€61). When you search for schedules and tickets, Omio will show you the best journey

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
14h 40m
Cheapest Price
$211 (€173)
Greyhound frequency
2 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.

BayRunner Shuttle

Luggage & cancellation policy
Average Duration
21h 55m
Cheapest Price
$360 (€295)
BayRunner Shuttle frequency
1 a day

FAQs: Bus from Frederick, MD to Buffalo, NY

Find answers to the most common questions about traveling from Frederick, MD to Buffalo, NY by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Buffalo, NY, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Frederick, MD to Buffalo, NY can start from as little as $75 (€61) when you book in advance. The average bus ticket price for Frederick, MD to Buffalo, NY is $82 (€67) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Frederick, MD to Buffalo, NY is 15h 20m to travel the 251 miles (405 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Frederick, MD to Buffalo, NY leaves at 12:55 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Frederick, MD to Buffalo, NY leaves at 11:55 PM.
There are 5 buses a day from Frederick, MD to Buffalo, NY which require at least one change with Greyhound, BayRunner Shuttle. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Frederick, MD to Buffalo, NY, you can count on Greyhound, BayRunner Shuttle for the best way to get you to Buffalo, NY. You can also check all possible bus companies who offer a service between Frederick, MD and Buffalo, NY and compare the amenities they offer before buying a bus ticket.
A trip to Buffalo, NY from Frederick, MD is worth doing but not as a day trip with a journey time of 15h 20m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Frederick, MD to Buffalo, NY is September.
It's helpful to compare your options as there are 2 ways to travel between Frederick, MD and Buffalo, NY including taking a bus and flight.
Yes, there are bathrooms on board the bus from Frederick, MD to Buffalo, NY for bus company Greyhound.
Yes, the following accessibility options are available when taking the bus from Frederick, MD to Buffalo, NY:
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
Whether you can cancel your bus ticket from Frederick, MD to Buffalo, NY depends on the bus companies:
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Frederick, MD to Buffalo, NY.
Yes, the following luggage options are included when booking a bus ticket from Frederick, MD to Buffalo, NY:
  • Greyhound
    • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Frederick, MD to Buffalo, NY:
  • Greyhound
    • $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Frederick, MD to Buffalo, NY.
You can reserve your seat on the bus from Frederick, MD to Buffalo, NY with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Frederick, MD to Buffalo, NY with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Frederick, MD to Buffalo, NY with the following bus company: Greyhound.

popular bus stations

Popular bus stations from Frederick, MD to Buffalo, NY

Frederick
Buffalo
The major bus station for departures in Frederick is Frederick, East Street (Transit Center). Find all the information you need to know about services, amenities and connections at Frederick, East Street (Transit Center) for your trip from Frederick to Buffalo.
Frederick, East Street (Transit Center)
information

More options for your journey from Frederick, MD to Buffalo, NY

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