- Must visit
Detroit Institute of Arts
World-class museum with Diego Rivera’s Detroit Industry murals and major collections spanning ancient to contemporary art.
Omio recommends booking the flight as it is the most popular option from Frederick, MD to Detroit, MI among Omio's users. If you are prioritising price take the bus with prices starting from $140. For those with little time consider booking a flight which can get you there in 1h 39m. The ticket price range depends on the travel mode: a bus costs an average of $140, and a flight costs an average of $356.
Distance: 356 miles (574 km)
| Bus | Most popular Flight |
|---|---|
$158 Average price Cheapest | $356 Average price |
14h 44m Average total duration 14h 14m Onboard + 30m Additional time* | 4h 39m Average total duration Fastest 1h 39m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options |
This is compared to other travel options from Frederick, MD to Detroit, MI:
A bus is $198 (€163) less than a flight for this route with tickets for a flight from Frederick, MD to Detroit, MI costing on average $356 (€294).
Other travel options to Detroit, MI take longer:
Bus takes on average 14h 14m.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:35AM | Arrival Time 02:10PM | Duration 13h35 | Departure days Wed | Cheapest price $183 |
Operator Greyhound | Departure Time 10:45AM | Arrival Time 02:55AM | Duration 16h10 | Departure days Wed | Cheapest price $140 |
Operator Greyhound | Departure Time 11:35PM | Arrival Time 01:10PM | Duration 13h35 | Departure days Wed | Cheapest price $147 |
The table below shows live departures for Frederick, MD to Detroit, MI buses for today, Wednesday, July 29. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 11:35 PM Frederick, MD | 13h35 | 1:10 PM Detroit, MI | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Frederick, MD to Detroit, MI run on average 2 times per day, taking around 14h 14m. Cheap bus tickets for this journey start at $140 (€115) if you book in advance.
The earliest bus runs at 06:45, the last at 23:00. The fastest bus covers the 356 miles (574 km) distance in 13h 35m.
Distance 356 miles (574 km) |
Average bus duration 14h 14m |
Cheapest ticket price $140 (€115) |
Buses per day 2 |
Fastest bus 13h 35m |
First bus 6:45 AM |
Last bus 11:00 PM |
Cheapest Month Aug |
Cheapest Day Thu |
High Season Jan - Mar |
Low Season Apr - Jun |
Discover the best of Detroit, MI — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Detroit, MI trip today.
World-class museum with Diego Rivera’s Detroit Industry murals and major collections spanning ancient to contemporary art.
Immersive museum of African American history, culture, and achievement with strong regional and national storytelling.
Motown’s original Studio A preserves the sound and stories behind legendary recordings that shaped popular music worldwide.
Riverfront promenade with public art, plazas, and skyline views; one of the city’s best places for a scenic walk.
Large island park with gardens, trails, beaches, and major attractions, offering a nature escape minutes from downtown.
Revived public square at the city center, hosting events, seasonal programming, and easy access to downtown landmarks.
A square deep-dish pizza with a crisp, caramelized cheese edge and striped sauce. It is Detroit’s signature pie, born in blue steel auto pans.
A hot dog topped with chili, mustard, and diced onions on a steamed bun. It is a classic Detroit street food tied to Greek-American diners.
A layered sandwich of corned beef, swiss cheese, coleslaw, and Russian dressing on grilled rye. It is a beloved deli staple in metro Detroit.
Acclaimed fine-dining restaurant focused on seasonal tasting menus and polished service. One of Detroit’s top special-occasion destinations.
Beloved Eastern Market bakery known for paczki, cakes, and old-school sweets. Expect a busy, nostalgic counter-service experience.
Historic downtown institution famous for Detroit-style square pizza in a lively, casual setting with old-school local character.
Moderate for US city breaks: hotels and dining are mid-priced, transit is limited, and car or rideshare costs can raise daily spend.
Tip 18-20% in restaurants, $1-2 per drink at bars, 10-15% for taxis, and spare change or about 10% in cafes if there is table service.
Find answers to the most common questions about traveling from Frederick, MD to Detroit, MI by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Detroit, MI, this guide helps you travel smarter and with confidence.

Most Frederick, MD to Detroit, MI buses use the Frederick, East Street (Transit Center) to Detroit, Greyhound Terminal station pair. Use this guide to compare Frederick, MD and Detroit, MI bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need