- Must visit
International Civil Rights Center & Museum
Major museum preserving the Woolworth sit-in site. Essential for understanding Greensboro's role in the American civil rights movement.
Cheapest price on Oct 29
$67
Average ticket price on Oct 29
$75
Fastest journey on Oct 29
8 h 50 m
Average journey duration on Oct 29
11 h 7 m
Buses on Oct 29
3
Distance
426 km
The best way to find a cheap bus ticket from Frederick, MD to Greensboro, NC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Frederick, MD to Greensboro, NC will cost around $75 if you buy it on the day, but the cheapest tickets can be found for only $67.
It's difficult to get from Frederick, MD to Greensboro, NC without transferring at least once.

|
| ||||||||||||

|
| ||||||||||||

|
| ||||||||||||

|
| ||||||||||||

|
| ||||||||||||

|
| ||||||||||||
Buses from Frederick, MD to Greensboro, NC run on average 3 times per day, taking around 8h 13m. Cheap bus tickets for this journey start at $110 if you book in advance.
The earliest bus runs at 00:20, the last at 23:05. The fastest bus covers the 264 miles (426 km) distance in 7h 55m.
Plan this route
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Frederick, MD to Greensboro, NC.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound USA | Departure Time 12:35AM | Arrival Time 09:25AM | Duration 8h50 | Departure days Mon, Tue, Thu, Fri, Sat | Cheapest price $67 |
Operator Greyhound USA | Departure Time 05:05AM | Arrival Time 03:35PM | Duration 10h30 | Departure days Everyday | Cheapest price $67 |
Operator Greyhound USA | Departure Time 10:25AM | Arrival Time 11:00PM | Duration 12h35 | Departure days Everyday | Cheapest price $67 |
Operator FlixBus | Departure Time 11:40PM | Arrival Time 09:25AM | Duration 9h45 | Departure days Wed | Cheapest price $119 |
The table below shows live departures for Frederick, MD to Greensboro, NC buses for today, Wednesday, October 28. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
· · | 10:25 AM Frederick, East Street (Transit Center) | 16h05 | 2:30 AM Greensboro, E Washington St (Greyhound Bus Station), NC | 2 transfers | |
| Thursday, October 29 | |||||
![]() | 12:35 AM Frederick, MD | 8h50 | 9:25 AM Greensboro, NC | 1 transfer | |
| Wednesday, October 28 | |||||
FlixBus+![]() | 11:40 PM Frederick, East Street (Transit Center) | 9h45 | 9:25 AM Greensboro, E Washington St (Greyhound Bus Station), NC | 1 transfer | |
| Thursday, October 29 | |||||
![]() | 5:05 AM Frederick, MD | 11h55 | 5:00 PM Greensboro, NC | 1 transfer | |
![]() | 10:25 AM Frederick, MD | 12h35 | 11:00 PM Greensboro, NC | 1 transfer | |
Find all the dates and times for this journey
Buses from Frederick, MD to Greensboro, NC with FlixBus and Greyhound. Overnight buses available on this route with FlixBus and Greyhound. Use the details below to compare onboard facilities.
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Greensboro, NC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Greensboro, NC trip today.
Major museum preserving the Woolworth sit-in site. Essential for understanding Greensboro's role in the American civil rights movement.
Leading regional art museum with American and international works, rotating exhibitions, and a sculpture collection near downtown.
Free city museum covering Greensboro's people, industries, and major events. A strong introduction to local history in the historic center.
Greensboro's main downtown street lined with shops, theaters, murals, and historic buildings. Best for strolling and city atmosphere.
Large urban park known for walking trails, sports fields, and the Bog Garden nearby. A versatile green space popular with locals.
Raised boardwalk through wetlands with shade, birds, and calm views. It is a peaceful local favorite for an easy nature walk.
North Carolina barbecue here often means slow-smoked pork with a tangy vinegar-based sauce, a Piedmont staple tied to family cookouts and old-school BBQ joints.
Barbecue slaw is a crisp cabbage slaw dressed with vinegar and ketchup, commonly piled on BBQ sandwiches across the Piedmont for bite and tang.
A classic Southern side of finely ground corn simmered until creamy. In Greensboro, it often appears with shrimp, gravy, or breakfast plates.
Historic fine-dining restaurant serving upscale Southern cuisine and steaks in an elegant clubhouse atmosphere near downtown.
Well-known local spot for hearty Southern breakfasts, biscuits, pancakes, and diner classics in a friendly, busy atmosphere.
Established venue for refined Southern and New American dishes, craft cocktails, and a polished but relaxed neighborhood feel.
Moderate for U.S. city breaks; hotels and dining are usually lower than major hubs, while car use can add to visitor costs.
Tip 18-20% at restaurants, 15-20% for taxis, and $1-2 per drink or café order if table service is provided.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Greensboro, NC.
Find answers to the most common questions about traveling from Frederick, MD to Greensboro, NC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Greensboro, NC, this guide helps you travel smarter and with confidence.

Most Frederick, MD to Greensboro, NC buses use the Frederick, East Street (Transit Center) to Greensboro, E Washington St (Greyhound Bus Station) station pair. Use this guide to compare Frederick, MD and Greensboro, NC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Frederick, East Street (Transit Center) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Frederick, East Street (Transit Center). ATMs are available at Frederick, East Street (Transit Center).
Ticket office support is available at Frederick, East Street (Transit Center).
Available at Frederick, East Street (Transit Center): Parking, Taxis, WC.
Accessibility facilities are available at Frederick, East Street (Transit Center): Wheelchair accessible entry and exit points.
Greensboro, E Washington St (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Greensboro, E Washington St (Greyhound Bus Station). ATMs are available at Greensboro, E Washington St (Greyhound Bus Station).
Ticket office support is available at Greensboro, E Washington St (Greyhound Bus Station).
Available at Greensboro, E Washington St (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Greensboro, E Washington St (Greyhound Bus Station): Wheelchair accessible entrance and facilities available.
Check bus stations information for Frederick, MD and Greensboro, NC, including where buses depart and arrive on this route.