- Must visit
Greensboro Science Center
A popular family-friendly complex combining an aquarium, museum, and zoo, known for interactive exhibits and broad appeal.
Cheapest price
$69
Average price
$69
Fastest journey
8 h 50 m
Average duration
10 h 38 m
Buses per day
3
Distance
426 km
The best way to find a cheap bus ticket from Frederick, MD to Greensboro, NC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Frederick, MD to Greensboro, NC will cost around $69 if you buy it on the day, but the cheapest tickets can be found for only $69.
It's difficult to get from Frederick, MD to Greensboro, NC without transferring at least once.






Omio recommends booking the train as it is the most popular option from Frederick, MD to Greensboro, NC among Omio's users. If you are prioritising price take the bus with prices starting from $69. For those with little time consider booking a bus which can get you there in 10h 52m. The ticket price range depends on the travel mode: a bus costs an average of $69, and a train costs an average of $159.
Distance: 264 miles (426 km)
| Bus | Most popular Train |
|---|---|
$71 Average price Cheapest | $159 Average price |
11h 22m Average total duration Fastest 10h 52m Onboard + 30m Additional time* | 12h 32m Average total duration 12h 2m Onboard + 30m Additional time* |
Direct Options | Direct Options |
This is compared to other travel options from Frederick, MD to Greensboro, NC:
A bus is $87 (€71) less than a train for this route with tickets for a train from Frederick, MD to Greensboro, NC costing on average $159 (€129).
Other travel options to Greensboro, NC take longer:
Train takes on average 12h 2m.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound USA | Departure Time 12:35AM | Arrival Time 09:25AM | Duration 8h50 | Departure days Mon, Tue, Wed, Thu, Fri, Sat | Cheapest price $69 |
Operator Greyhound USA | Departure Time 05:05AM | Arrival Time 03:35PM | Duration 10h30 | Departure days Everyday | Cheapest price $69 |
Operator Greyhound USA | Departure Time 10:25AM | Arrival Time 11:00PM | Duration 12h35 | Departure days Everyday | Cheapest price $69 |
The table below shows live departures for Frederick, MD to Greensboro, NC buses for today, Sunday, June 14. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 5:05 AM Frederick, MD | 10h30 | 3:35 PM Greensboro, NC | 1 transfer | |
![]() | 10:25 AM Frederick, MD | 12h35 | 11:00 PM Greensboro, NC | 1 transfer | |
| Monday, June 15 | |||||
![]() | 12:35 AM Frederick, MD | 8h50 | 9:25 AM Greensboro, NC | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Frederick, MD to Greensboro, NC run on average 2 times per day, taking around 10h 52m. Cheap bus tickets for this journey start at $69 (€56) if you book in advance.
The earliest bus runs at 00:20, the last at 23:05. The fastest bus covers the 264 miles (426 km) distance in 8h 50m.
Distance 264 miles (426 km) |
Average bus duration 10h 52m |
Cheapest ticket price $69 (€56) |
Buses per day 2 |
Fastest bus 8h 50m |
First bus 12:20 AM |
Last bus 11:05 PM |
Cheapest Month Jun |
Cheapest Day Sat |
High Season Jan - Mar |
Low Season Apr - Jun |
Discover the best of Greensboro — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Greensboro trip today.
A popular family-friendly complex combining an aquarium, museum, and zoo, known for interactive exhibits and broad appeal.
A nationally significant museum at the former Woolworth building, interpreting the Greensboro sit-ins and the civil rights movement.
The university art museum with a strong modern and contemporary collection, widely regarded as one of the city’s best cultural stops.
The city’s main walkable core, mixing historic blocks, murals, theaters, museums, and nightlife-oriented public spaces.
A large historic park with trails, monuments, and interpretive stops, combining outdoor walking with Revolutionary War history.
A landscaped public garden with seasonal color, sculptures, and easy paths, popular for photos and quiet walks.
Slow-smoked pork shoulder chopped or pulled and dressed in a tangy vinegar-based sauce, a classic Piedmont and statewide barbecue tradition.
A regional red slaw made with cabbage and a lightly sweet vinegar-tomato dressing, commonly served on barbecue sandwiches across central North Carolina.
Fluffy Southern biscuits filled with salty cured ham, a breakfast staple in North Carolina and a familiar comfort food in Greensboro.
A popular casual spot recognized for creative burgers, good beer selection, and lively neighborhood energy.
A polished bistro at Proximity Hotel known for seasonal American fare, strong brunch, and an upscale yet relaxed setting.
An established restaurant offering European-influenced American cuisine, dependable service, and a refined dining room popular for dinner and brunch.
Costs are generally moderate for U.S. travel, with affordable dining and parking, while hotels vary by season and events.
Tip 18-20% at restaurants; 20%+ for excellent service. Tip USD 1-2 per drink at bars, round up taxis, and tip hotel staff and delivery drivers.
Find answers to the most common questions about traveling from Frederick, MD to Greensboro, NC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Greensboro, NC, this guide helps you travel smarter and with confidence.

Here are some other resources that might have the information you need