- Must visit
International Civil Rights Center & Museum
Major museum preserving the Woolworth sit-in site. Essential for understanding Greensboro's role in the American civil rights movement.
Cheapest price
$68
Average price
$76
Fastest journey
8 h 50 m
Average duration
11 h 7 m
Buses per day
3
Distance
426 km
The best way to find a cheap bus ticket from Frederick, MD to Greensboro, NC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Frederick, MD to Greensboro, NC will cost around $76 if you buy it on the day, but the cheapest tickets can be found for only $68.
It's difficult to get from Frederick, MD to Greensboro, NC without transferring at least once.






Omio recommends booking the train as it is the most popular option from Frederick, MD to Greensboro, NC among Omio's users. If you are prioritising price take the bus with prices starting from $68. For those with little time consider booking a bus which can get you there in 10h 52m. The ticket price range depends on the travel mode: a bus costs an average of $68, and a train costs an average of $157.
Distance: 264 miles (426 km)
| Bus | Most popular Train |
|---|---|
$70 Average price Cheapest | $157 Average price |
11h 22m Average total duration Fastest 10h 52m Onboard + 30m Additional time* | 12h 32m Average total duration 12h 2m Onboard + 30m Additional time* |
Direct Options | Direct Options |
This is compared to other travel options from Frederick, MD to Greensboro, NC:
A bus is $86 (€71) less than a train for this route with tickets for a train from Frederick, MD to Greensboro, NC costing on average $157 (€129).
Other travel options to Greensboro, NC take longer:
Train takes on average 12h 2m.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound USA | Departure Time 12:35AM | Arrival Time 09:25AM | Duration 8h50 | Departure days Mon, Tue, Thu, Fri, Sat | Cheapest price $68 |
Operator Greyhound USA | Departure Time 05:05AM | Arrival Time 03:35PM | Duration 10h30 | Departure days Everyday | Cheapest price $67 |
Operator FlixBus | Departure Time 10:25AM | Arrival Time 11:00PM | Duration 12h35 | Departure days Wed | Cheapest price $70 |
Operator Greyhound USA | Departure Time 10:25AM | Arrival Time 11:00PM | Duration 12h35 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $68 |
Operator FlixBus | Departure Time 11:35PM | Arrival Time 09:25AM | Duration 9h50 | Departure days Wed | Cheapest price $70 |
The table below shows live departures for Frederick, MD to Greensboro, NC buses for today, Wednesday, July 29. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 12:35 AM Frederick, MD | 8h50 | 9:25 AM Greensboro, NC | 1 transfer | |
| Wednesday, July 29 | |||||
FlixBus+![]() | 11:35 PM Frederick, East Street (Transit Center) | 9h50 | 9:25 AM Greensboro, E Washington St (Greyhound Bus Station), NC | 1 transfer | |
| Thursday, July 30 | |||||
![]() | 5:05 AM Frederick, MD | 11h55 | 5:00 PM Greensboro, NC | 1 transfer | |
![]() | 10:25 AM Frederick, MD | 12h35 | 11:00 PM Greensboro, NC | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Frederick, MD to Greensboro, NC run on average 2 times per day, taking around 10h 52m. Cheap bus tickets for this journey start at $68 (€56) if you book in advance.
The earliest bus runs at 00:20, the last at 23:05. The fastest bus covers the 264 miles (426 km) distance in 8h 50m.
Distance 264 miles (426 km) |
Average bus duration 10h 52m |
Cheapest ticket price $68 (€56) |
Buses per day 2 |
Fastest bus 8h 50m |
First bus 12:20 AM |
Last bus 11:05 PM |
Cheapest Month Jun |
Cheapest Day Sat |
High Season Jan - Mar |
Low Season Apr - Jun |
Discover the best of Greensboro, NC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Greensboro, NC trip today.
Major museum preserving the Woolworth sit-in site. Essential for understanding Greensboro's role in the American civil rights movement.
Leading regional art museum with American and international works, rotating exhibitions, and a sculpture collection near downtown.
Free city museum covering Greensboro's people, industries, and major events. A strong introduction to local history in the historic center.
Greensboro's main downtown street lined with shops, theaters, murals, and historic buildings. Best for strolling and city atmosphere.
Large urban park known for walking trails, sports fields, and the Bog Garden nearby. A versatile green space popular with locals.
Raised boardwalk through wetlands with shade, birds, and calm views. It is a peaceful local favorite for an easy nature walk.
North Carolina barbecue here often means slow-smoked pork with a tangy vinegar-based sauce, a Piedmont staple tied to family cookouts and old-school BBQ joints.
Barbecue slaw is a crisp cabbage slaw dressed with vinegar and ketchup, commonly piled on BBQ sandwiches across the Piedmont for bite and tang.
A classic Southern side of finely ground corn simmered until creamy. In Greensboro, it often appears with shrimp, gravy, or breakfast plates.
Historic fine-dining restaurant serving upscale Southern cuisine and steaks in an elegant clubhouse atmosphere near downtown.
Well-known local spot for hearty Southern breakfasts, biscuits, pancakes, and diner classics in a friendly, busy atmosphere.
Established venue for refined Southern and New American dishes, craft cocktails, and a polished but relaxed neighborhood feel.
Moderate for U.S. city breaks; hotels and dining are usually lower than major hubs, while car use can add to visitor costs.
Tip 18-20% at restaurants, 15-20% for taxis, and $1-2 per drink or café order if table service is provided.
Find answers to the most common questions about traveling from Frederick, MD to Greensboro, NC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Greensboro, NC, this guide helps you travel smarter and with confidence.

Most Frederick, MD to Greensboro, NC buses use the Frederick, East Street (Transit Center) to Greensboro, E Washington St (Greyhound Bus Station) station pair. Use this guide to compare Frederick, MD and Greensboro, NC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need