- Must visit
Tampa Museum of Art
Major art museum on the Riverwalk with Greek and Roman antiquities, modern art, and a strong photography collection.
Omio recommends booking the train as it is the most popular option from Frederick, MD to Tampa, FL among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $210 For those with little time, consider booking a bus, which has an average total journey time of 26h 51m. Average ticket prices depend on the travel mode: a bus costs an average of $210, while a bus costs an average of $210.
Distance: 843 miles (1357 km)
| Bus | Most popular Train | Driving |
|---|---|---|
$210 Average price Cheapest | $194 Average price (fuel + tolls) | |
26h 51m Average total duration Fastest 26h 21m Onboard + 30m Additional time* | 13h 56m Average total duration (door-to-door) | |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Frederick, MD to Tampa, FL:
A bus is $652 less than a flight for this route with tickets for a flight from Frederick, MD to Tampa, FL costing on average $861.
Other travel options to Tampa, FL take longer:
Bus takes on average 26h 21m.
Tickets start at around $210 compared to roughly $194 in fuel and tolls — a saving of about $-15.53. The journey takes 26h 21m versus 13h 56m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 05:05AM | Arrival Time 12:45PM | Duration 31h40 | Departure days Thu | Cheapest price $122 |
Operator FlixBus | Departure Time 05:05AM | Arrival Time 12:45PM | Duration 31h40 | Departure days Tue, Fri | Cheapest price $119 |
Operator FlixBus | Departure Time 10:25AM | Arrival Time 10:25PM | Duration 36h00 | Departure days Thu | Cheapest price $120 |
Operator FlixBus | Departure Time 02:25PM | Arrival Time 01:25PM | Duration 47h00 | Departure days Wed | Cheapest price $218 |
Operator BayRunner Shuttle | Departure Time 07:15PM | Arrival Time 10:25PM | Duration 27h10 | Departure days Sun | Cheapest price $282 |
Operator FlixBus | Departure Time 11:40PM | Arrival Time 10:25PM | Duration 22h45 | Departure days Tue, Thu, Fri | Cheapest price $127 |
Operator Greyhound | Departure Time 11:40PM | Arrival Time 06:40AM | Duration 31h00 | Departure days Tue, Thu, Fri | Cheapest price $99 |
The table below shows live departures for Frederick, MD to Tampa, FL buses for today, Sunday, September 13. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 7:15 PM Frederick, MD | 27h10 | 10:25 PM Tampa, FL | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Frederick, MD to Tampa, FL run on average 4 times per day, taking around 26h 21m. Cheap bus tickets for this journey start at $130 if you book in advance.
The earliest bus runs at 01:05, the last at 22:35. The fastest bus covers the 843 miles (1357 km) distance in 24h 0m.
Distance 843 miles (1357 km) |
Average bus duration 26h 21m |
Cheapest ticket price $130 |
Buses per day 4 |
Fastest bus 24h 0m |
First bus 1:05 AM |
Last bus 10:35 PM |
Cheapest Month Mar |
Cheapest Day Wed |
High Season Jul - Sep |
Low Season Oct - Dec |
Discover the best of Tampa, FL — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Tampa, FL trip today.
Major art museum on the Riverwalk with Greek and Roman antiquities, modern art, and a strong photography collection.
Engaging family-friendly museum exploring Tampa Bay history through exhibits on pirates, cigars, industry, and local communities.
Fascinating history museum inside the former Tampa Bay Hotel, showcasing Gilded Age rooms, décor, and Florida tourism heritage.
Scenic waterfront promenade linking parks, museums, and downtown landmarks; ideal for walking, biking, and skyline views.
Tampa's most historic district, known for brick streets, cigar heritage, nightlife, and a distinctive Cuban and immigrant legacy.
Popular bayside path and green space on Davis Islands with sweeping water views, downtown panoramas, and sunset appeal.
A Cuban sandwich layered with roast pork, ham, salami, Swiss cheese, pickles, and mustard on pressed Cuban bread. Tampa's version is a defining local classic.
Deviled crab is a Tampa staple: seasoned blue crab mixed with Cuban bread crumbs, shaped into a shell-like croquette, then breaded and fried.
A chilled espresso drink sweetened and shaken until frothy. Popular in Tampa's Cuban communities, it is a local coffee ritual and social pick-me-up.
Beloved Tampa institution known for deviled crab, Cuban sandwiches, and casual old-Tampa counter service.
Upscale modern Spanish restaurant in historic Ybor, known for refined tapas, cocktails, and a polished dining room.
Historic Ybor City restaurant famed for the original Tampa Cuban sandwich and old-school Spanish-Cuban atmosphere.
Moderate for U.S. beach cities: hotels can be high in peak season, but dining and local transport are usually manageable for most visitors.
Tip 15-20% at restaurants, 18-22% for great service. Taxis usually 10-15%. For cafes, small change or $1 per drink is common but optional.
Official public transport app
Tampa International Airport -> Downtown Tampa, Tampa, FL
Find answers to the most common questions about traveling from Frederick, MD to Tampa, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Tampa, FL, this guide helps you travel smarter and with confidence.

Most Frederick, MD to Tampa, FL buses use the Frederick, East Street (Transit Center) to Tampa, Marion Transit Center station pair, with some services arriving at Tampa, USF Holly Drive (Central Plant). Use this guide to compare Frederick, MD and Tampa, FL bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Frederick, East Street (Transit Center) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Frederick, East Street (Transit Center). ATMs are available at Frederick, East Street (Transit Center).
Ticket office support is available at Frederick, East Street (Transit Center).
Available at Frederick, East Street (Transit Center): Parking, Taxis, WC.
Accessibility facilities are available at Frederick, East Street (Transit Center): Wheelchair accessible entry and exit points.
Tampa, Marion Transit Center has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Tampa, Marion Transit Center. ATMs are available at Tampa, Marion Transit Center.
Ticket office support is available at Tampa, Marion Transit Center.
Available at Tampa, Marion Transit Center: Parking, Taxis, WC.
Accessibility facilities are available at Tampa, Marion Transit Center: Wheelchair accessible with ramps.
Tampa, USF Holly Drive (Central Plant) is 13 km from Tampa city centre. Public transport options include:
Tampa, USF Holly Drive (Central Plant) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Tampa, USF Holly Drive (Central Plant). ATMs are available at Tampa, USF Holly Drive (Central Plant).
Ticket office support is available at Tampa, USF Holly Drive (Central Plant).
Available at Tampa, USF Holly Drive (Central Plant): Parking, Taxis, WC.
Accessibility facilities are available at Tampa, USF Holly Drive (Central Plant): Wheelchair accessible facilities.
Here are some other resources that might have the information you need