- Must visit
Musée des Confluences
A major science and anthropology museum in a striking contemporary building at the confluence of the Rhône and Saône. One of Lyon’s signature cultural sites with strong temporary exhibitions.
Cheapest price
$52
Average price
$97
Fastest journey
10 h 40 m
Average duration
11 h 8 m
Buses per day
17
Distance
551 km
The best way to find a cheap bus ticket from Florence to Lyon is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Florence to Lyon will cost around $97 if you buy it on the day, but the cheapest tickets can be found for only $52.
Of the 17 buses that leave Florence for Lyon on Wed, Jun 03, 7 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, Jun 03 the direct buses cover the 551 km distance in an average of 11 h 8 m but if you time it right, some buses will get you there in just 10 h 40 m .
On Wed, Jun 03 the slowest buses will take 11 h 40 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
4788
2126 · 3092
3492
FlixBus
FlixBus
FlixBus
4788
3492
FlixBus
FlixBusOmio recommends booking the bus as it is the most popular option from Florence to Lyon among Omio's users. If you are prioritising price take the bus with prices starting from $19. For those with little time consider booking a flight which can get you there in 3h 17m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.6 - 1.4kg. The ticket price range depends on the travel mode: a bus costs an average of $19, and a flight costs an average of $44.
Distance: 342 miles (551 km)
Most popular Bus | Train | Flight |
|---|---|---|
$46 Average price Cheapest | $153 Average price | $231 Average price |
14h 9m Average total duration 13h 39m Onboard + 30m Additional time* | 8h 53m Average total duration 8h 23m Onboard + 30m Additional time* | 6h 17m Average total duration Fastest 3h 17m Onboard + 3h 0m Additional time* |
0.6 - 1.4kg CO2 emissions Lowest | - CO2 emissions | 1.7 - 3.3kg CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Florence to Lyon:
A bus is $107 (€86) less than a train for this route with tickets for a train from Florence to Lyon costing on average $153 (€123).
A bus is $185 (€149) less than a flight for this route with tickets for a flight from Florence to Lyon costing on average $231 (€187).
Other travel options to Lyon take longer:
Train takes on average 8h 23m.
Bus takes on average 13h 39m.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:05AM | Arrival Time 12:00PM | Duration 11h55 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $100 |
Operator Itabus | Departure Time 01:05AM | Arrival Time 12:55PM | Duration 11h50 | Departure days Everyday | Cheapest price $43 |
Operator FlixBus | Departure Time 01:50AM | Arrival Time 02:10PM | Duration 12h20 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $71 |
Operator FlixBus | Departure Time 02:15AM | Arrival Time 03:05PM | Duration 12h50 | Departure days Everyday | Cheapest price $94 |
Operator FlixBus | Departure Time 02:40AM | Arrival Time 03:05PM | Duration 12h25 | Departure days Everyday | Cheapest price $81 |
Operator FlixBus | Departure Time 05:05AM | Arrival Time 06:10PM | Duration 13h05 | Departure days Everyday | Cheapest price $79 |
Operator FlixBus | Departure Time 07:30AM | Arrival Time 06:10PM | Duration 10h40 | Departure days Everyday | Cheapest price $64 |
Operator BlaBlaCar | Departure Time 10:00AM | Arrival Time 06:20PM | Duration 8h20 | Departure days Mon | Cheapest price $66 |
Operator Itabus | Departure Time 10:20AM | Arrival Time 09:30PM | Duration 11h10 | Departure days Everyday | Cheapest price $43 |
Operator FlixBus | Departure Time 11:15AM | Arrival Time 11:45PM | Duration 12h30 | Departure days Everyday | Cheapest price $82 |
Operator Itabus | Departure Time 11:55AM | Arrival Time 12:25AM | Duration 12h30 | Departure days Everyday | Cheapest price $41 |
Operator FlixBus | Departure Time 12:00PM | Arrival Time 10:40PM | Duration 10h40 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $51 |
Operator FlixBus | Departure Time 12:30PM | Arrival Time 11:45PM | Duration 11h15 | Departure days Everyday | Cheapest price $64 |
Operator BlaBlaCar Bus | Departure Time 02:15PM | Arrival Time 01:20AM | Duration 11h05 | Departure days Thu, Fri, Sat, Sun | Cheapest price $50 |
Operator FlixBus | Departure Time 03:35PM | Arrival Time 05:55AM | Duration 14h20 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $81 |
Operator Itabus | Departure Time 04:20PM | Arrival Time 04:55AM | Duration 12h35 | Departure days Thu, Fri, Sat, Sun | Cheapest price $42 |
Operator RegioJet a.s. | Departure Time 04:45PM | Arrival Time 02:50PM | Duration 46h05 | Departure days Wed | Cheapest price $149 |
Operator FlixBus | Departure Time 04:45PM | Arrival Time 03:55AM | Duration 11h10 | Departure days Tue | Cheapest price $123 |
Operator FlixBus | Departure Time 06:45PM | Arrival Time 06:30AM | Duration 11h45 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $66 |
Operator BlaBlaCar Bus | Departure Time 07:10PM | Arrival Time 06:05AM | Duration 10h55 | Departure days Wed, Thu, Sat, Sun | Cheapest price $50 |
Operator FlixBus | Departure Time 09:05PM | Arrival Time 08:45AM | Duration 11h40 | Departure days Everyday | Cheapest price $64 |
Operator FlixBus | Departure Time 10:20PM | Arrival Time 12:00PM | Duration 13h40 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $71 |
Operator FlixBus | Departure Time 11:40PM | Arrival Time 12:00PM | Duration 12h20 | Departure days Everyday | Cheapest price $71 |
The table below shows live departures for Florence to Lyon buses for today, Tuesday, June 2. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus | 7:30 AM Scandicci, Villa Costanza (Florence) | 10h40 | 6:10 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
3492 | 10:20 AM Scandicci, Villa Costanza (Florence) | 11h10 | 9:30 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
FlixBus · FlixBus | 11:15 AM Florence, Guidoni Tram T2 | 12h30 | 11:45 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
2126 · 3092 | 11:55 AM Scandicci, Villa Costanza (Florence) | 12h30 | 12:25 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus | 12:30 PM Scandicci, Villa Costanza (Florence) | 11h15 | 11:45 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
FlixBus · FlixBus | 4:45 PM Scandicci, Villa Costanza (Florence) | 11h10 | 3:55 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus | 9:05 PM Scandicci, Villa Costanza (Florence) | 11h40 | 8:45 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
FlixBus · FlixBus | 11:40 PM Firenze, Piazzale Montelungo | 12h20 | 12:00 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
| Wednesday, June 3 | |||||
FlixBus · FlixBus | 12:05 AM Scandicci, Villa Costanza (Florence) | 11h55 | 12:00 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
3898 | 1:05 AM Scandicci, Villa Costanza (Florence) | 11h50 | 12:55 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
FlixBus · FlixBus | 2:15 AM Firenze, Piazzale Montelungo | 12h50 | 3:05 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus · FlixBus | 2:40 AM Scandicci, Villa Costanza (Florence) | 12h25 | 3:05 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus · FlixBus | 5:05 AM Firenze, Piazzale Montelungo | 13h05 | 6:10 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, flight, and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Florence to Lyon run on average 16 times per day, taking around 13h 39m. Cheap bus tickets for this journey start at $19 (€15) if you book in advance.
There are 7 buses per day. The earliest bus runs at 00:05, the last at 23:50. The fastest bus covers the 342 miles (551 km) distance in 10h 40m.
Distance 342 miles (551 km) |
Average bus duration 13h 39m |
Cheapest ticket price $19 (€15) |
Buses per day 16 |
Direct buses 7 |
Fastest bus 10h 40m |
First bus 12:05 AM |
Last bus 11:50 PM |
Cheapest Month May |
Cheapest Day Thu |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Mon |
Least Busy Day Sat |
Best time to book 84 days |
Discover the best of Lyon — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Lyon trip today.
A major science and anthropology museum in a striking contemporary building at the confluence of the Rhône and Saône. One of Lyon’s signature cultural sites with strong temporary exhibitions.
Lyon’s premier fine arts museum, housed in a former abbey near Place des Terreaux. Known for strong collections of painting, sculpture, antiquities, and decorative arts.
Museum of Roman Lyon paired with the city’s ancient theaters on Fourvière hill. A key stop for understanding Lugdunum, the Roman origins of Lyon.
Lyon’s atmospheric old quarter with Renaissance lanes, traboules, and riverfront views. It is the city’s classic strolling area and a top priority for first-time visitors.
One of Europe’s largest open squares and a central meeting point in Lyon. It is a practical orientation stop and a key place for city views toward Fourvière.
Lyon’s flagship urban park with broad walking paths, lake, botanical areas, and a zoo. It is one of the best places in the city for relaxation and scenic walks.
Light dumplings made with pike and panade, usually baked in a rich Nantua crayfish sauce. A classic Lyonnais bouchon specialty.
A traditional salad of frisée lettuce with lardons, croutons, and a poached egg. It is one of the city’s most iconic starter dishes.
Lyon’s famous sausage baked inside a soft brioche dough. It is a beloved charcuterie-based specialty found in many bouchons.
A landmark fine dining institution in Lyon, famed for historic prestige and elegant cuisine rooted in the city’s gastronomic heritage.
The city’s celebrated covered food market, ideal for sampling oysters, charcuterie, cheese, pastries, and many iconic Lyonnais products.
A respected traditional restaurant associated with chef Joseph Viola, celebrated for refined Lyonnais classics in a polished but welcoming setting.
Moderate for France: bakeries and bouchons are fair value, while central hotels and fine dining cost more.
Service is included by law. Leaving small change or 5-10% for great service is appreciated, not required. Round up for taxis.
Official public transport app
Lyon Perrache Bus Station, Lyon -> Lyon Part-Dieu Station, Lyon
Find answers to the most common questions about traveling from Florence to Lyon by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Lyon, this guide helps you travel smarter and with confidence.

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