- Must visit
The Children's Museum of Indianapolis
World-class children's museum with science, history, dinosaurs, sports, and immersive exhibits. One of Indianapolis's signature attractions for all ages.
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The cheapest and fastest buses from Columbia, MO to Indianapolis, IN
Showing times and prices for Aug 06
Cheapest price
$103
Average price
$103
Fastest journey
10 h 20 m
Average duration
10 h 20 m
Buses per day
1
Distance
539 km
Cheap tickets
The best way to find a cheap bus ticket from Columbia, MO to Indianapolis, IN is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Columbia, MO to Indianapolis, IN will cost around $103 if you buy it on the day, but the cheapest tickets can be found for only $103.
Fast buses
Of the 1 buses that leave Columbia, MO for Indianapolis, IN on Thu, Aug 06, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Aug 06 the direct buses cover the 539 km distance in an average of 10 h 20 m but if you time it right, some buses will get you there in just 10 h 20 m .
On Thu, Aug 06 the slowest buses will take 10 h 20 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
1:05 AM10h20Columbia, MO11:25 AMIndianapolis, IN$1031One-way0 transfers
- 1:05 AM10h20Columbia, MO11:25 AMIndianapolis, IN$1031One-way0 transfers
Travel Information
Compare bus and flight for Columbia, MO to Indianapolis, IN
Omio recommends booking the flight as it is the most popular option from Columbia, MO to Indianapolis, IN among Omio's users. If you are prioritising price take the bus with prices starting from $62. For those with little time consider booking a flight which can get you there in 4h 28m. The ticket price range depends on the travel mode: a bus costs an average of $62, and a flight costs an average of $420.
Distance: 334 miles (539 km)
Compare bus with
| Bus | Most popular Flight | Driving |
|---|---|---|
$88 Average price Cheapest | $988 Average price | $73 Average price (fuel + tolls) |
10h 35m Average total duration 10h 5m Onboard + 30m Additional time* | 7h 28m Average total duration Fastest 4h 28m Onboard + 3h 0m Additional time* | 5h 24m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Columbia, MO to Indianapolis, IN is a bus with an average price of $88.
This is compared to other travel options from Columbia, MO to Indianapolis, IN:
A bus is $900 less than a flight for this route with tickets for a flight from Columbia, MO to Indianapolis, IN costing on average $988.
The fastest way to travel from Columbia, MO to Indianapolis, IN is by flight with an average journey time of 4h 28m.
Other travel options to Indianapolis, IN take longer:
Bus takes on average 10h 5m.
It's helpful to compare your options as there are 2 ways to travel between Columbia, MO and Indianapolis, IN including taking a bus and flight.
We recommend using the bus as it is the most popular way to get from Columbia, MO to Indianapolis, IN among Omio's users.
Take the bus. On this route, it's both cheaper and quicker than driving.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Columbia, MO to Indianapolis, IN Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 01:05AM | Arrival Time 11:25AM | Duration 10h20 | Departure days Thu | Cheapest price $103 |
Operator Greyhound | Departure Time 02:05AM | Arrival Time 12:25PM | Duration 10h20 | Departure days Sat | Cheapest price $62 |
Operator Greyhound | Departure Time 08:30AM | Arrival Time 07:20PM | Duration 9h50 | Departure days Mon, Tue, Thu, Sat, Sun | Cheapest price $56 |
Operator Greyhound | Departure Time 10:40AM | Arrival Time 07:20PM | Duration 7h40 | Departure days Mon, Tue, Thu, Sat, Sun | Cheapest price $56 |
Operator Greyhound | Departure Time 08:05PM | Arrival Time 07:30AM | Duration 10h25 | Departure days Mon, Tue, Thu, Sat, Sun | Cheapest price $57 |
Operator FlixBus | Departure Time 08:05PM | Arrival Time 11:50AM | Duration 14h45 | Departure days Mon, Tue, Thu, Sat, Sun | Cheapest price $57 |
Operator Greyhound | Departure Time 08:35PM | Arrival Time 07:30AM | Duration 9h55 | Departure days Mon, Tue, Thu, Sat, Sun | Cheapest price $56 |
Operator FlixBus | Departure Time 08:35PM | Arrival Time 11:50AM | Duration 14h15 | Departure days Mon, Tue, Thu, Sat, Sun | Cheapest price $56 |
Live departures
Columbia, MO to Indianapolis, IN bus times
The table below shows live departures for Columbia, MO to Indianapolis, IN buses for today, Tuesday, August 4. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| · | 8:30 AM Columbia, Wabash Bus Station, MO | 9h50 | 7:20 PM Indianapolis, Illinois St (Greyhound Bus Station) | 1 transfer | |
| · | 10:40 AM Columbia, Highway 40 W (Midway Truck Plaza), MO | 7h40 | 7:20 PM Indianapolis, Illinois St (Greyhound Bus Station) | 1 transfer | |
+ FlixBus · FlixBus | 8:05 PM Columbia, Wabash Bus Station, MO | 14h45 | 11:50 AM Indianapolis, E Washington St / N Delaware St (City/County Building), IN | 2 transfers | |
| · | 8:05 PM Columbia, Wabash Bus Station, MO | 10h25 | 7:30 AM Indianapolis, Illinois St (Greyhound Bus Station) | 1 transfer | |
| Wednesday, August 5 | |||||
| 1:05 AM Columbia, MO | 10h20 | 11:25 AM Indianapolis, IN | 0 transfersDirect | |
| +FlixBus · FlixBus | 8:35 PM Columbia, Highway 40 W (Midway Truck Plaza), MO | 14h15 | 11:50 AM Indianapolis, E Washington St / N Delaware St (City/County Building), IN | 2 transfers | |
| · | 8:35 PM Columbia, Highway 40 W (Midway Truck Plaza), MO | 9h55 | 7:30 AM Indianapolis, Illinois St (Greyhound Bus Station) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Columbia, MO to Indianapolis, IN by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Columbia, MO to Indianapolis, IN buses with Omio?
Greyhound operates all buses services from Columbia, MO to Indianapolis, IN.
Omio is an official ticket reseller for all your travel options from Columbia, MO to Indianapolis, IN.
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Columbia, MO to Indianapolis, IN.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Columbia, MO to Indianapolis, IN.
Journey information
Overview: Bus from Columbia, MO to Indianapolis, IN
USAUSA
Buses from Columbia, MO to Indianapolis, IN run on average 4 times per day, taking around 10h 5m. Cheap bus tickets for this journey start at $62 if you book in advance.
The earliest bus runs at 03:30, the last at 20:35. The fastest bus covers the 334 miles (539 km) distance in 9h 50m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 334 miles (539 km) |
Average bus duration 10h 5m |
Cheapest ticket price $62 |
Buses per day 4 |
Fastest bus 9h 50m |
First bus 3:30 AM |
Last bus 8:35 PM |
Cheapest Month Oct |
Cheapest Day Fri |
High Season Apr - Jun |
Low Season Jul - Sep |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: Greyhound from Columbia, MO to Indianapolis, INYou can travel by bus between Columbia, MO to Indianapolis, IN with Greyhound for as low as $62. When you search for schedules and tickets, Omio will show you the best journey
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
9h 50m
Cheapest Price
$62
Greyhound frequency
4 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Complete guide to Indianapolis, IN
Things to do in Indianapolis, IN
Discover the best of Indianapolis, IN — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Indianapolis, IN trip today.
- Must visit
Indianapolis Museum of Art at Newfields
Leading art museum set on the Newfields campus, with major collections from Europe, Asia, Africa, and America plus temporary exhibitions.
- Recommended
Benjamin Harrison Presidential Site
Museum and restored home of the 23rd U.S. president. Guided visits reveal politics, domestic life, and architecture from the late 1800s.
- Must visit
Central Canal
Pedestrian-friendly downtown canal lined with museums, public art, and boats. Ideal for a scenic walk and one of the city's most popular areas.
- Must visit
Monument Circle
Historic city center surrounding the Soldiers and Sailors Monument. A signature urban space for architecture, events, and classic downtown views.
- Must visit
Indianapolis Cultural Trail
Popular cultural trail linking downtown districts with public art, bike lanes, and green streetscape design. Perfect for exploring the city on foot.
Pork Tenderloin Sandwich
Indiana pork tenderloin sandwich is a breaded, fried cutlet served on a bun, often comically oversized. It is a beloved statewide classic common in Indianapolis pubs and diners.
- Vegetarian
Sugar Cream Pie
Sugar cream pie is Indiana's state pie, made with cream, sugar, and nutmeg. Its simple farm-pantry origins make it a traditional Hoosier dessert tied closely to local identity.
- Gluten-free
St. Elmo-Style Shrimp Cocktail
Shrimp cocktail in Indianapolis style features chilled shrimp with very spicy tomato-horseradish sauce. St. Elmo made this fiery version a city dining icon.
Vida
Established fine-dining restaurant serving seasonal Midwestern cuisine with polished service. Known for refined plates and a warm, contemporary atmosphere.
St. Elmo Steak House
Historic downtown steakhouse famous for aged steaks and the city's iconic fiery shrimp cocktail. Classic, upscale atmosphere with longstanding local prestige.
Harry & Izzy's
Long-running Indianapolis institution known for classic steaks, seafood, and old-school service. A traditional downtown choice with historic local character.
United States Dollar ($)
Moderate for a U.S. city: hotels and dining are mid-range, while transit is limited so many visitors use rideshare or rental cars.
Average meal costs
- Budget
- $10-$18 for fast food or a casual meal.
- Mid-range
- $20-$40 per person for a restaurant meal.
- Fine dining
- $60+ per person for upscale dining.
- Coffee
- $3-$6 for coffee or a cappuccino.
Tipping culture
Tip 18-20% at restaurants, $1-$2 per drink at bars, and 10-15% for taxis. Small cafe tips are appreciated but optional.
FAQs: Bus from Columbia, MO to Indianapolis, IN
Find answers to the most common questions about traveling from Columbia, MO to Indianapolis, IN by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Indianapolis, IN, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Columbia, MO to Indianapolis, IN can start from as little as $62 when you book in advance. The average bus ticket price for Columbia, MO to Indianapolis, IN is $88 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Columbia, MO to Indianapolis, IN is 9h 50m to travel the 334 miles (539 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Columbia, MO to Indianapolis, IN leaves at 3:30 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Columbia, MO to Indianapolis, IN leaves at 8:35 PM.
There are 4 buses a day from Columbia, MO to Indianapolis, IN which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Columbia, MO to Indianapolis, IN, you can count on Greyhound for the best way to get you to Indianapolis, IN. You can also check all possible bus companies who offer a service between Columbia, MO and Indianapolis, IN and compare the amenities they offer before buying a bus ticket.
A trip to Indianapolis, IN from Columbia, MO is worth doing but not as a day trip with a journey time of 9h 50m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Columbia, MO to Indianapolis, IN is October.
It's helpful to compare your options as there are 2 ways to travel between Columbia, MO and Indianapolis, IN including taking a bus and flight.
Yes, the following accessibility options are available when taking the bus from Columbia, MO to Indianapolis, IN:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Columbia, MO to Indianapolis, IN for bus company Greyhound.
Some of the most interesting sights to explore in Indianapolis, IN are:
- Indianapolis Motor Speedway, a historic racing circuit known for hosting the Indianapolis 500
- The Children's Museum of Indianapolis, the world's largest children's museum featuring interactive exhibits
- Indianapolis Zoo, a popular attraction with diverse animal exhibits and a botanical garden
- Indiana State Museum, showcasing the state's history, art, and science through various exhibits
- White River State Park, a sprawling urban park offering trails, gardens, and cultural attractions.
The best things to do in Indianapolis, IN include:
- Indianapolis Museum of Art at Newfields, a vast art museum with extensive collections and beautiful gardens
- Attend a race at the Indianapolis Motor Speedway, home of the iconic Indy 500
- Explore the interactive exhibits and educational programs at The Children's Museum of Indianapolis
- Visit the dolphin pavilion and animal habitats at the Indianapolis Zoo
- Enjoy a walk along the canal and cultural attractions at White River State Park.
Whether you can cancel your bus ticket from Columbia, MO to Indianapolis, IN depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Columbia, MO to Indianapolis, IN.
Yes, the following luggage options are included when booking a bus ticket from Columbia, MO to Indianapolis, IN:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Columbia, MO to Indianapolis, IN:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Columbia, MO to Indianapolis, IN.
You can reserve your seat on the bus from Columbia, MO to Indianapolis, IN with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Columbia, MO to Indianapolis, IN with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Columbia, MO to Indianapolis, IN with the following bus company: Greyhound.
Since neither Columbia, MO nor Indianapolis, IN are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the bus as it is the most popular way to get from Columbia, MO to Indianapolis, IN among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Indianapolis, travelers should be cautious of pickpocketing and vehicle break-ins, especially in busy areas like downtown and near major event venues. Common scams include overcharging by unofficial taxi or rideshare drivers and distraction tactics used to steal belongings. It's advised to use authorized transportation services, avoid poorly lit or unfamiliar areas at night, and keep valuables secure.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Columbia, MO to Indianapolis, IN
Most Columbia, MO to Indianapolis, IN buses use the Columbia, Highway 40 W (Midway Truck Plaza) to Indianapolis, Illinois St (Greyhound Bus Station) station pair, with some services arriving at Indianapolis, E Washington St / N Delaware St (City/County Building). Use this guide to compare Columbia, MO and Indianapolis, IN bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Columbia
Arrival bus stations in Indianapolis
Columbia, Highway 40 W (Midway Truck Plaza)
City-centre transport
Getting to Columbia, Highway 40 W (Midway Truck Plaza) from Columbia city centre
TrainMissouri River Runner, Lincoln Service Missouri River Runner · 4h 1m · $226
BusGreyhound US0175s · 2h 45m · $25
Columbia, Wabash Bus Station
Indianapolis, Illinois St (Greyhound Bus Station)
Indianapolis, E Washington St / N Delaware St (City/County Building)
Most popular bus connections from Columbia, MO
More options for your journey from Columbia, MO to Indianapolis, IN
Here are some other resources that might have the information you need
Most popular buses to and from Indianapolis, IN and Columbia, MO
Most popular bus connections to Indianapolis, IN
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