Columbia, MO to Indianapolis, IN bus with Greyhound

Sat, Sep 19
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The cheapest and fastest buses from Columbia, MO to Indianapolis, IN

Showing times, prices and bookable tickets for Sep 19

Cheapest price on Sep 19

Kč1727

Average ticket price on Sep 19

Kč1727

Fastest journey on Sep 19

9 h 50 m

Average journey duration on Sep 19

9 h 50 m

Buses on Sep 19

1

Distance

539 km

Cheap tickets

The best way to find a cheap bus ticket from Columbia, MO to Indianapolis, IN is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Columbia, MO to Indianapolis, IN will cost around Kč1727 if you buy it on the day, but the cheapest tickets can be found for only Kč1727.

Fast buses

On Sat, Sep 19, we found 1 buses from Columbia, MO to Indianapolis, IN, including 1 direct services.

On Sat, Sep 19 the direct buses cover the 539 km distance in an average of 9 h 50 m but if you time it right, some buses will get you there in just 9 h 50 m .

On Sat, Sep 19 the slowest buses will take 9 h 50 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

  • Greyhound
    1:30 PM9h50
    Columbia, MO
    11:20 PMIndianapolis, IN
    17271One-way
    0 transfers

Travel Information

Compare bus for Columbia, MO to Indianapolis, IN

Omio recommends booking the bus as it is the most popular option from Columbia, MO to Indianapolis, IN among Omio's users. If you are prioritising price, take the bus, with an average ticket price of Kč1357 For those with little time, consider booking a bus, which has an average total journey time of 9h 34m. Average ticket prices depend on the travel mode: a bus costs an average of Kč1357, while a bus costs an average of Kč1357.

Distance: 334 miles (539 km)

Compare bus with

Most popular
Bus
Driving

Kč1357

Average price

Cheapest

Kč1570

Average price

(fuel + tolls)

9h 34m

Average total duration

Fastest

9h 4m

Onboard

+

30m

Additional time*

5h 24m

Average total duration

(door-to-door)

Greyhound

Most popular bus company

Your own car or car rental

Direct Options

Direct Options

The cheapest way to travel from Columbia, MO to Indianapolis, IN is a bus with an average price of Kč1357.
The fastest way to travel from Columbia, MO to Indianapolis, IN is by bus with an average journey time of 9h 4m.
Yes, you can take a bus between Columbia, MO and Indianapolis, IN.
We recommend using the bus as it is the most popular way to get from Columbia, MO to Indianapolis, IN among Omio's users.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.

Tickets start at around Kč1357 compared to roughly Kč1570 in fuel and tolls — a saving of about Kč213. The journey takes 9h 4m versus 5h 24m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.

Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.

Columbia, MO to Indianapolis, IN Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
Greyhound
Departure Time
01:05AM
Arrival Time
11:25AM
Duration
10h20
Departure days
Thu
Cheapest price
2167
Operator
Greyhound
Departure Time
08:30AM
Arrival Time
07:30PM
Duration
10h00
Departure days
Mon, Tue, Thu, Fri, Sun
Cheapest price
1022
Operator
Greyhound
Departure Time
10:40AM
Arrival Time
07:30PM
Duration
7h50
Departure days
Mon, Fri, Sun
Cheapest price
1022
Operator
Greyhound
Departure Time
01:30PM
Arrival Time
11:20PM
Duration
9h50
Departure days
Sat
Cheapest price
1727
Operator
Greyhound
Departure Time
08:05PM
Arrival Time
07:25AM
Duration
10h20
Departure days
Mon, Tue, Thu, Fri, Sun
Cheapest price
1022
Operator
FlixBus
Departure Time
08:05PM
Arrival Time
11:50AM
Duration
14h45
Departure days
Mon, Fri, Sun
Cheapest price
1048
Operator
Greyhound
Departure Time
08:35PM
Arrival Time
07:25AM
Duration
9h50
Departure days
Mon, Fri, Sun
Cheapest price
1035
Operator
FlixBus
Departure Time
08:35PM
Arrival Time
11:50AM
Duration
14h15
Departure days
Mon, Fri, Sun
Cheapest price
1035

Live departures

Columbia, MO to Indianapolis, IN bus times

The table below shows live departures for Columbia, MO to Indianapolis, IN buses for today, Friday, September 18. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
Greyhound · 8:30 AM Columbia, Wabash Bus Station, MO
10h00
7:30 PM Indianapolis, Illinois St (Greyhound Bus Station)1 transfer
Greyhound · 10:40 AM Columbia, Highway 40 W (Midway Truck Plaza), MO
7h50
7:30 PM Indianapolis, Illinois St (Greyhound Bus Station)1 transfer
Greyhound · 8:05 PM Columbia, Wabash Bus Station, MO
10h20
7:25 AM Indianapolis, Illinois St (Greyhound Bus Station)1 transfer
Greyhound+FlixBusFlixBus · FlixBus8:05 PM Columbia, Wabash Bus Station, MO
14h45
11:50 AM Indianapolis, E Washington St / N Delaware St (City/County Building), IN2 transfers
Greyhound+FlixBusFlixBus · FlixBus8:35 PM Columbia, Highway 40 W (Midway Truck Plaza), MO
14h15
11:50 AM Indianapolis, E Washington St / N Delaware St (City/County Building), IN2 transfers
Greyhound · 8:35 PM Columbia, Highway 40 W (Midway Truck Plaza), MO
9h50
7:25 AM Indianapolis, Illinois St (Greyhound Bus Station)1 transfer

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Columbia, MO to Indianapolis, IN by bus

Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Sat
Sep 19
Sun
Sep 20
Mon
Sep 21
Tue
Sep 22
Wed
Sep 23
Thu
Sep 24
Fri
Sep 25

Why should you book Columbia, MO to Indianapolis, IN buses with Omio?

Greyhound operates all buses services from Columbia, MO to Indianapolis, IN.
Omio is an official ticket reseller for all your travel options from Columbia, MO to Indianapolis, IN.

Why book with Omio vs Greyhound?

  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.

Journey information

Overview: Bus from Columbia, MO to Indianapolis, IN

USAUSA
USAUSA
Icon of bus

Buses from Columbia, MO to Indianapolis, IN run on average 6 times per day, taking around 9h 4m. Cheap bus tickets for this journey start at Kč1100 if you book in advance.

The earliest bus runs at 03:30, the last at 20:35. The fastest bus covers the 334 miles (539 km) distance in 6h 40m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
334 miles (539 km)
Average bus duration
9h 4m
Cheapest ticket price
Kč1100
Buses per day
6
Fastest bus
6h 40m
First bus
3:30 AM
Last bus
8:35 PM
Cheapest Month
Aug
Cheapest Day
Thu
High Season
Jul - Sep
Low Season
Oct - Dec
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: Greyhound, FlixBus from Columbia, MO to Indianapolis, INYou can travel by bus between Columbia, MO to Indianapolis, IN with Greyhound, FlixBus for as low as Kč1100. When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
12h 15m
Cheapest FlixBus Price
Kč1100
FlixBus frequency
2 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
6h 40m
Cheapest Greyhound Price
Kč1113
Greyhound frequency
4 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.

Complete guide to Indianapolis, IN

Things to do in Indianapolis, IN

Discover the best of Indianapolis, IN — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Indianapolis, IN trip today.

  • Must visit

The Children's Museum of Indianapolis

World-class children's museum with science, history, dinosaurs, sports, and immersive exhibits. One of Indianapolis's signature attractions for all ages.

  • Must visit

Indianapolis Museum of Art at Newfields

Leading art museum set on the Newfields campus, with major collections from Europe, Asia, Africa, and America plus temporary exhibitions.

  • Recommended

Benjamin Harrison Presidential Site

Museum and restored home of the 23rd U.S. president. Guided visits reveal politics, domestic life, and architecture from the late 1800s.

United States Dollar ($)

Moderate for a U.S. city: hotels and dining are mid-range, while transit is limited so many visitors use rideshare or rental cars.

Average meal costs

Budget
$10-$18 for fast food or a casual meal.
Mid-range
$20-$40 per person for a restaurant meal.
Fine dining
$60+ per person for upscale dining.
Coffee
$3-$6 for coffee or a cappuccino.

Tipping culture

Tip 18-20% at restaurants, $1-$2 per drink at bars, and 10-15% for taxis. Small cafe tips are appreciated but optional.

FAQs: Bus from Columbia, MO to Indianapolis, IN

Find answers to the most common questions about traveling from Columbia, MO to Indianapolis, IN by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Indianapolis, IN, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Columbia, MO to Indianapolis, IN can start from as little as Kč1100 when you book in advance. The average bus ticket price for Columbia, MO to Indianapolis, IN is Kč1357 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Columbia, MO to Indianapolis, IN is 6h 40m to travel the 334 miles (539 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Columbia, MO to Indianapolis, IN leaves at 3:30 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Columbia, MO to Indianapolis, IN leaves at 8:35 PM.
There are 6 buses a day from Columbia, MO to Indianapolis, IN which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Columbia, MO to Indianapolis, IN, you can count on Greyhound for the best way to get you to Indianapolis, IN. You can also check all possible bus companies who offer a service between Columbia, MO and Indianapolis, IN and compare the amenities they offer before buying a bus ticket.
When departing from Columbia, MO , you have various bus station options to start your journey from including Columbia, Highway 40 W (Midway Truck Plaza), MO, Columbia, Wabash Bus Station, MO . When arriving in Indianapolis, IN , you can end your journey in bus stations like Indianapolis, Illinois St (Greyhound Bus Station) .Passengers board the bus most frequently from Columbia, Highway 40 W (Midway Truck Plaza), MO, which is located around 4 miles (8 km) away from the city centre, and they get off the bus at Indianapolis, Illinois St (Greyhound Bus Station), located 0 away from the city centre.
A trip to Indianapolis, IN from Columbia, MO is worth doing but not as a day trip with a journey time of 6h 40m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Columbia, MO to Indianapolis, IN is August.
Yes, you can take a bus between Columbia, MO and Indianapolis, IN.
Yes, the following accessibility options are available when taking the bus from Columbia, MO to Indianapolis, IN:
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Columbia, MO to Indianapolis, IN for bus company Greyhound.
Some of the most interesting sights to explore in Indianapolis, IN are:
  • Indianapolis Motor Speedway, a historic racing circuit known for hosting the Indianapolis 500
  • The Children's Museum of Indianapolis, the world's largest children's museum featuring interactive exhibits
  • Indianapolis Zoo, a popular attraction with diverse animal exhibits and a botanical garden
  • Indiana State Museum, showcasing the state's history, art, and science through various exhibits
  • White River State Park, a sprawling urban park offering trails, gardens, and cultural attractions.
The best things to do in Indianapolis, IN include:
  • Indianapolis Museum of Art at Newfields, a vast art museum with extensive collections and beautiful gardens
  • Attend a race at the Indianapolis Motor Speedway, home of the iconic Indy 500
  • Explore the interactive exhibits and educational programs at The Children's Museum of Indianapolis
  • Visit the dolphin pavilion and animal habitats at the Indianapolis Zoo
  • Enjoy a walk along the canal and cultural attractions at White River State Park.
Whether you can cancel your bus ticket from Columbia, MO to Indianapolis, IN depends on the bus companies:
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Columbia, MO to Indianapolis, IN.
Yes, the following luggage options are included when booking a bus ticket from Columbia, MO to Indianapolis, IN:
  • Greyhound
    • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Columbia, MO to Indianapolis, IN:
  • Greyhound
    • $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Columbia, MO to Indianapolis, IN.
You can reserve your seat on the bus from Columbia, MO to Indianapolis, IN with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Columbia, MO to Indianapolis, IN with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Columbia, MO to Indianapolis, IN with the following bus company: Greyhound.
Since neither Columbia, MO nor Indianapolis, IN are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the bus as it is the most popular way to get from Columbia, MO to Indianapolis, IN among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Indianapolis, travelers should be cautious of pickpocketing and vehicle break-ins, especially in busy areas like downtown and near major event venues. Common scams include overcharging by unofficial taxi or rideshare drivers and distraction tactics used to steal belongings. It's advised to use authorized transportation services, avoid poorly lit or unfamiliar areas at night, and keep valuables secure.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from Columbia, MO to Indianapolis, IN

Most Columbia, MO to Indianapolis, IN buses use the Columbia, Wabash Bus Station to Indianapolis, Illinois St (Greyhound Bus Station) station pair. Use this guide to compare Columbia, MO and Indianapolis, IN bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.

Departure bus stations in Columbia
Arrival bus stations in Indianapolis

Which Columbia, MO station do buses to Indianapolis, IN leave from?

Buses from Columbia, MO to Indianapolis, IN leave from Columbia, Highway 40 W (Midway Truck Plaza). The station is 5 miles (9 km) from Columbia, MO city centre at US-40, United States.
Columbia, Highway 40 W (Midway Truck Plaza)US-40, United StatesWifiParkingDiningATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to Columbia, Highway 40 W (Midway Truck Plaza) from Columbia city centre

Columbia, Highway 40 W (Midway Truck Plaza) is 8 km from Columbia city centre. Public transport options include:

TrainMissouri River Runner, Lincoln Service Missouri River Runner · 4h 1m · Kč4765
BusGreyhound US0175s · 2h 45m · Kč518

Columbia, Highway 40 W (Midway Truck Plaza) bus station facilities and services

Columbia, Highway 40 W (Midway Truck Plaza) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Food and drink

Food options include: Several fast food options available within the plaza.

Wi-Fi and ATMs

Wi-Fi available inside the truck plaza building. ATMs are aTM machines are available inside the truck plaza.

Tickets and information

Ticket office support is available at Columbia, Highway 40 W (Midway Truck Plaza).

Parking, taxis and toilets

Available at Columbia, Highway 40 W (Midway Truck Plaza): Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at Columbia, Highway 40 W (Midway Truck Plaza): Wheelchair accessible facilities available.

Columbia, Wabash Bus Station126 N 10th St, Columbia, MO 65201, USAWifiParkingATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to Columbia, Wabash Bus Station from Columbia city centre

TRUE

Columbia, Wabash Bus Station bus station facilities and services

Columbia, Wabash Bus Station has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Wi-Fi and ATMs

Wi-Fi is available at Columbia, Wabash Bus Station. ATMs are available at Columbia, Wabash Bus Station.

Tickets and information

Ticket office support is available at Columbia, Wabash Bus Station.

Parking, taxis and toilets

Available at Columbia, Wabash Bus Station: Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at Columbia, Wabash Bus Station: Station is accessible for wheelchair users.

More options for your journey from Columbia, MO to Indianapolis, IN

Here are some other resources that might have the information you need

HomeBusesBuses in USABus tickets to Indianapolis, INColumbia, MO to Indianapolis, IN bus

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