- Must visit
National Civil Rights Museum
World-class civil rights museum at the Lorraine Motel. Essential for understanding the movement, Dr. King, and the American struggle for justice.
The best way to find a cheap bus ticket from Columbia, MO to Memphis, TN is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Columbia, MO to Memphis, TN will cost around $104 if you buy it on the day, but the cheapest tickets can be found for only $92.
It's difficult to get from Columbia, MO to Memphis, TN without transferring at least 2 times.

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Buses from Columbia, MO to Memphis, TN run on average 4 times per day, taking around 7h 53m. Cheap bus tickets for this journey start at $51 if you book in advance.
The earliest bus runs at 04:05, the last at 22:45. The fastest bus covers the 291 miles (469 km) distance in 7h 0m.
Plan this route
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Columbia, MO to Memphis, TN.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 01:05AM | Arrival Time 11:30AM | Duration 10h25 | Departure days Fri | Cheapest price $96 |
Operator FlixBus | Departure Time 08:30AM | Arrival Time 08:45PM | Duration 12h15 | Departure days Sun | Cheapest price $58 |
Operator Greyhound USA | Departure Time 08:30AM | Arrival Time 06:04AM | Duration 21h34 | Departure days Mon, Tue, Wed | Cheapest price $92 |
Operator FlixBus | Departure Time 10:40AM | Arrival Time 08:45PM | Duration 10h05 | Departure days Sun | Cheapest price $58 |
Operator Greyhound USA | Departure Time 08:05PM | Arrival Time 07:55AM | Duration 11h50 | Departure days Mon, Tue, Wed, Fri, Sun | Cheapest price $57 |
Operator Greyhound | Departure Time 08:35PM | Arrival Time 06:30AM | Duration 9h55 | Departure days Sun | Cheapest price $57 |
The table below shows live departures for Columbia, MO to Memphis, TN buses for today, Monday, November 2. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 8:05 PM Columbia, MO | 11h50 | 7:55 AM Memphis, TN | 2 transfers | |
| Tuesday, November 3 | |||||
![]() | 8:30 AM Columbia, MO | 21h34 | 6:04 AM Memphis, TN | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Buses from Columbia, MO to Memphis, TN with Greyhound and FlixBus. Overnight buses available on this route with Greyhound and FlixBus. Use the details below to compare onboard facilities.
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Memphis, TN — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Memphis, TN trip today.
World-class civil rights museum at the Lorraine Motel. Essential for understanding the movement, Dr. King, and the American struggle for justice.
Major museum of Memphis music history inside a former recording studio. A must for soul, blues, and rock fans exploring the city's sound.
Interactive museum on Stax Records and Southern soul legends. Worth visiting for Otis Redding, Isaac Hayes, and immersive music storytelling.
Memphis's legendary entertainment street, famous for live music, neon, and history. A classic walk for atmosphere, nightlife, and cultural identity.
Mississippi riverfront park with broad lawns, monuments, and skyline views. Ideal for an easy walk and classic river scenery.
Large urban park with old-growth forest, trails, playgrounds, and zoo access. Excellent for nature, families, and a break from downtown.
Memphis-style pork ribs are slow-smoked over hardwood, usually served dry-rubbed or lightly sauced. They are the city’s most iconic barbecue tradition.
Pulled pork shoulder is smoked until tender, chopped or shredded, and often topped with slaw. It is a staple of Memphis barbecue joints.
Barbecue spaghetti mixes smoked pork, tomato-based sauce, and spaghetti. This quirky Memphis specialty reflects the city’s barbecue creativity.
Beloved traditional barbecue spot famous for pulled pork sandwiches, ribs, and barbecue spaghetti. Casual and deeply tied to Memphis food culture.
Historic fine dining destination serving refined Southern cuisine and an acclaimed brunch. Elegant setting inside a former mansion in Midtown.
Long-running Memphis institution for fried chicken and Southern sides. Bustling, family-friendly atmosphere with a strong local following.
Moderate for U.S. city breaks: hotels and dining are generally below New York or Miami, while car, rideshare, and attraction costs can add up.
Tip 18-20% in restaurants, more for great service. Taxis usually 10-15%. Cafes often have tip jars or card prompts; small tips are appreciated.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Memphis, TN.
Find answers to the most common questions about traveling from Columbia, MO to Memphis, TN by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Memphis, TN, this guide helps you travel smarter and with confidence.

Most Columbia, MO to Memphis, TN buses use the Columbia, Highway 40 W (Midway Truck Plaza) to Memphis, Airways Transit Center station pair. Use this guide to compare Columbia, MO and Memphis, TN bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Columbia, Highway 40 W (Midway Truck Plaza) is 8 km from Columbia city centre. Public transport options include:
Columbia, Highway 40 W (Midway Truck Plaza) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Several fast food options available within the plaza.
Wi-Fi available inside the truck plaza building. ATMs are aTM machines are available inside the truck plaza.
Ticket office support is available at Columbia, Highway 40 W (Midway Truck Plaza).
Available at Columbia, Highway 40 W (Midway Truck Plaza): Parking, Taxis, WC.
Accessibility facilities are available at Columbia, Highway 40 W (Midway Truck Plaza): Wheelchair accessible facilities available.
Columbia, Wabash Bus Station has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Columbia, Wabash Bus Station. ATMs are available at Columbia, Wabash Bus Station.
Ticket office support is available at Columbia, Wabash Bus Station.
Available at Columbia, Wabash Bus Station: Parking, Taxis, WC.
Accessibility facilities are available at Columbia, Wabash Bus Station: Station is accessible for wheelchair users.
Memphis, Airways Transit Center is 11 km from Memphis city centre. Public transport options include:
Memphis, Airways Transit Center has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Multiple restaurants and food services available.
Free Wi-Fi available throughout the station. ATMs are aTMs available inside the station building.
Ticket office support is available at Memphis, Airways Transit Center.
Available at Memphis, Airways Transit Center: Parking, Taxis, WC.
Accessibility facilities are available at Memphis, Airways Transit Center: Wheelchair accessible with assistance available.
Check bus stations information for Columbia, MO and Memphis, TN, including where buses depart and arrive on this route.