Travel Information
Compare bus for Columbia, MO to San Diego, CA
Omio recommends booking the bus as it is the most popular option from Columbia, MO to San Diego, CA among Omio's users. If you are prioritising price take the bus with prices starting from $583. For those with little time consider booking a bus which can get you there in 50h 10m. The ticket price range depends on the travel mode: a bus costs an average of $583, and a bus costs an average of $583.
Distance: 1450 miles (2334 km)
Compare bus with
Most popular Bus | Driving |
|---|---|
$583 Average price Cheapest | $343 Average price (fuel + tolls) |
50h 40m Average total duration Fastest 50h 10m Onboard + 30m Additional time* | 25h 29m Average total duration (door-to-door) |
Direct Options | Direct Options |
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Columbia, MO to San Diego, CA Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound USA | Departure Time 08:05PM | Arrival Time 10:15PM | Duration 50h10 | Departure days Mon, Tue, Wed, Sun | Cheapest price $583 |
Live departures
Columbia, MO to San Diego, CA bus times
The table below shows live departures for Columbia, MO to San Diego, CA buses for today, Wednesday, May 27. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 8:05 PM Columbia, MO | 50h10 | 10:15 PM San Diego, CA | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Columbia, MO to San Diego, CA by bus
Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Jun 03
Why should you book Columbia, MO to San Diego, CA buses with Omio?
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
Journey information
Overview: Bus from Columbia, MO to San Diego, CA
Buses from Columbia, MO to San Diego, CA run on average 14 times per day, taking around 50h 10m. Cheap bus tickets for this journey start at $583 (€470) if you book in advance.
The earliest bus runs at 06:45, the last at 20:35. The fastest bus covers the 1450 miles (2334 km) distance in 50h 10m.
Distance 1450 miles (2334 km) |
Average bus duration 50h 10m |
Cheapest ticket price $583 (€470) |
Buses per day 14 |
Fastest bus 50h 10m |
First bus 6:45 AM |
Last bus 8:35 PM |
High Season Apr - Jun |
Low Season Apr - Jun |
Bus providers: Greyhound from Columbia, MO to San Diego, CAYou can travel by bus between Columbia, MO to San Diego, CA with Greyhound for as low as $583 (€470). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from Columbia, MO to San Diego, CA
Find answers to the most common questions about traveling from Columbia, MO to San Diego, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Diego, CA, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Balboa Park, a sprawling urban park with museums, gardens, and the San Diego Zoo
- USS Midway Museum, a historic naval aircraft carrier museum offering interactive exhibits and tours
- La Jolla Cove, a picturesque coastal area known for its stunning views and marine life
- Gaslamp Quarter, a lively historic district with Victorian architecture, dining, and entertainment options
- Coronado Beach, a beautiful sandy beach known for its gentle waves and iconic hotel.
- Explore the vibrant art scene at the Museum of Contemporary Art San Diego
- enjoy a harbor cruise for stunning views of the skyline and naval ships
- hike the scenic trails at Torrey Pines State Natural Reserve
- visit the Birch Aquarium to learn about marine life and ocean conservation
- experience the thrill of a whale watching tour off the coast.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Columbia, MO to San Diego, CA
Most popular bus connections from Columbia, MO
More options for your journey from Columbia, MO to San Diego, CA
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