The cheapest and fastest buses from Columbia, MO to San Francisco, CA
Cheapest price
$884
Average price
$910
Fastest journey
2 d 19 h 20 m
Average duration
2 d 19 h 20 m
Buses per day
2
Distance
2614 km
The best way to find a cheap bus ticket from Columbia, MO to San Francisco, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Columbia, MO to San Francisco, CA will cost around $910 if you buy it on the day, but the cheapest tickets can be found for only $884.
It's difficult to get from Columbia, MO to San Francisco, CA without transferring at least 2 times.




Compare prices and tickets Columbia, MO to San Francisco, CA by bus
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Journey information
Overview: Bus from Columbia, MO to San Francisco, CA
Buses from Columbia, MO to San Francisco, CA run on average 6 times per day, taking around 67h 20m. Cheap bus tickets for this journey start at $889 (€713) if you book in advance.
The earliest bus runs at 06:30, the last at 23:25. The fastest bus covers the 1624 miles (2614 km) distance in 67h 20m.
Distance 1624 miles (2614 km) |
Average bus duration 67h 20m |
Cheapest ticket price $889 (€713) |
Buses per day 6 |
Fastest bus 67h 20m |
First bus 06:30 |
Last bus 23:25 |
Bus providers: Greyhound from Columbia, MO to San Francisco, CAYou can travel by bus between Columbia, MO to San Francisco, CA with Greyhound for as low as $889 (€713). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from Columbia, MO to San Francisco, CA
Find answers to the most common questions about traveling from Columbia, MO to San Francisco, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Francisco, CA, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Golden Gate Bridge, an iconic suspension bridge offering panoramic views of the San Francisco Bay
- Alcatraz Island, a historic site featuring the infamous former prison and informative audio tours
- Fisherman's Wharf, a bustling waterfront area known for seafood, shops, and sea lions
- Golden Gate Park, a large urban park with gardens, museums, and recreational activities
- Chinatown, the oldest and one of the largest Chinatowns in North America, offering vibrant culture and cuisine.
- Ride a cable car through the steep streets of San Francisco for a classic city experience
- Explore the vibrant murals and street art in the Mission District
- Visit the Exploratorium, an interactive science museum perfect for all ages
- Take a scenic walk along the Embarcadero, offering views of the Bay Bridge and access to the Ferry Building Marketplace
- Enjoy a wine tasting tour in nearby Napa Valley, a short drive from the city.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
To find the cheapest bus tickets for your trip from Columbia, MO to San Francisco, CA, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Columbia, MO to San Francisco, CA
Most popular bus connections from Columbia, MO
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