- Must visit
San Francisco Museum of Modern Art
Major contemporary art museum with an outstanding modern and contemporary collection, large-scale installations, and strong photography holdings.
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The cheapest and fastest buses from Columbia, MO to San Francisco, CA
Showing times and prices for Jun 21
Cheapest price
$540
Average price
$540
Fastest journey
1 d 21 h 45 m
Average duration
1 d 21 h 45 m
Buses per day
1
Distance
2614 km
Cheap tickets
The best way to find a cheap bus ticket from Columbia, MO to San Francisco, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Columbia, MO to San Francisco, CA will cost around $540 if you buy it on the day, but the cheapest tickets can be found for only $540.
Fast buses
It's difficult to get from Columbia, MO to San Francisco, CA without transferring at least 3 times.
2:40 PM45h45Columbia, MO12:25 PMSan Francisco, CA$5401One-way3 transfers
- 2:40 PM45h45Columbia, MO12:25 PMSan Francisco, CA$5401One-way3 transfers
Travel Information
Compare bus and flight for Columbia, MO to San Francisco, CA
Omio recommends booking the flight as it is the most popular option from Columbia, MO to San Francisco, CA among Omio's users. If you are prioritising price take the bus with prices starting from $266. For those with little time consider booking a flight which can get you there in 8h 18m. The ticket price range depends on the travel mode: a bus costs an average of $266, and a flight costs an average of $417.
Distance: 1624 miles (2614 km)
Compare bus with
| Bus | Most popular Flight | Driving |
|---|---|---|
$266 Average price Cheapest | $417 Average price | $389 Average price (fuel + tolls) |
48h 15m Average total duration 47h 45m Onboard + 30m Additional time* | 11h 18m Average total duration Fastest 8h 18m Onboard + 3h 0m Additional time* | 28h 17m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Columbia, MO to San Francisco, CA is a bus with an average price of $266 (€217).
This is compared to other travel options from Columbia, MO to San Francisco, CA:
A bus is $151 (€123) less than a flight for this route with tickets for a flight from Columbia, MO to San Francisco, CA costing on average $417 (€341).
The fastest way to travel from Columbia, MO to San Francisco, CA is by flight with an average journey time of 8h 18m.
Other travel options to San Francisco, CA take longer:
Bus takes on average 47h 45m.
It's helpful to compare your options as there are 2 ways to travel between Columbia, MO and San Francisco, CA including taking a bus and flight.
We recommend using the bus as it is the most popular way to get from Columbia, MO to San Francisco, CA among Omio's users.
Take the bus. On this route, it's both cheaper and quicker than driving.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Columbia, MO to San Francisco, CA Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound USA | Departure Time 02:40PM | Arrival Time 12:25PM | Duration 45h45 | Departure days Mon, Tue, Wed, Sun | Cheapest price $540 |
Operator Greyhound | Departure Time 07:40PM | Arrival Time 07:25PM | Duration 47h45 | Departure days Thu | Cheapest price $266 |
Compare prices and tickets Columbia, MO to San Francisco, CA by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Columbia, MO to San Francisco, CA buses with Omio?
Greyhound operates all buses services from Columbia, MO to San Francisco, CA.
Omio is an official ticket reseller for all your travel options from Columbia, MO to San Francisco, CA.
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Columbia, MO to San Francisco, CA.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Columbia, MO to San Francisco, CA.
Journey information
Overview: Bus from Columbia, MO to San Francisco, CA
USAUSA
Buses from Columbia, MO to San Francisco, CA run on average 6 times per day, taking around 47h 45m. Cheap bus tickets for this journey start at $266 (€217) if you book in advance.
The earliest bus runs at 07:46, the last at 23:25. The fastest bus covers the 1624 miles (2614 km) distance in 47h 45m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 1624 miles (2614 km) |
Average bus duration 47h 45m |
Cheapest ticket price $266 (€217) |
Buses per day 6 |
Fastest bus 47h 45m |
First bus 7:46 AM |
Last bus 11:25 PM |
Cheapest Month Mar |
Cheapest Day Thu |
High Season Jan - Mar |
Low Season Jan - Mar |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: Greyhound from Columbia, MO to San Francisco, CAYou can travel by bus between Columbia, MO to San Francisco, CA with Greyhound for as low as $266 (€217). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
47h 45m
Cheapest Price
$266 (€217)
Greyhound frequency
6 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Complete guide to San Francisco
Things to do in San Francisco
Discover the best of San Francisco — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect San Francisco trip today.
- Must visit
Exploratorium
Interactive science and art museum on the Embarcadero, especially popular for hands-on exhibits and bayfront setting.
- Recommended
de Young Museum
Fine arts museum in Golden Gate Park known for American art, textiles, rotating exhibitions, and its panoramic observation tower.
- Must visit
Lombard Street
The famously crooked block lined with flowers and city views, one of San Francisco's most photographed streets.
- Must visit
Golden Gate Park
Massive urban park with gardens, lakes, museums, and broad walking space that rewards both short visits and full-day exploration.
- Must visit
Twin Peaks
High viewpoint with sweeping panoramic views over the city and bay, especially popular at sunset and on clear mornings.
- Gluten-free
Cioppino
A tomato-based seafood stew created by Italian fishermen in San Francisco, usually filled with crab, clams, mussels, shrimp, and fish. It is one of the city’s signature dishes.
- Vegetarian
- Vegan
Sourdough Bread
San Francisco sourdough is famous for its tangy flavor and chewy crust, shaped by the city’s historic baking culture and local wild yeast tradition.
Mission-Style Burrito
A large burrito associated with the Mission District, typically packed with rice, beans, meat, salsa, and extras. It is a defining San Francisco street food.
Sotto Mare
North Beach favorite specializing in cioppino and classic seafood in a lively, casual setting.
La Taqueria
Iconic Mission District taqueria celebrated for Mission-style burritos and tacos with a no-frills local vibe.
The Buena Vista
Classic waterfront cafe famous for Irish Coffee, hearty breakfasts, and historic cable-car-adjacent charm.
United States Dollar
One of the priciest U.S. cities. Hotels, dining, parking, and taxes add up quickly, though transit and casual food can help control costs.
Average meal costs
- Budget
- USD 12-20 for fast casual or food trucks.
- Mid-range
- USD 25-45 per person at a standard restaurant.
- Fine dining
- USD 90+ per person before drinks and tax.
- Coffee
- USD 4-7 for drip coffee or a latte.
Tipping culture
Restaurants: 18-22% is standard before or after tax depending on the screen shown. Bars: USD 1-2 per drink. Taxis/rideshare: 10-15% or round up. Hotel staff: USD 2-5 for porters, a few USD nightly for housekeeping.
FAQs: Bus from Columbia, MO to San Francisco, CA
Find answers to the most common questions about traveling from Columbia, MO to San Francisco, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Francisco, CA, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Columbia, MO to San Francisco, CA can start from as little as $266 (€217) when you book in advance. The average bus ticket price for Columbia, MO to San Francisco, CA is $266 (€217) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Columbia, MO to San Francisco, CA is 47h 45m to travel the 1624 miles (2614 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Columbia, MO to San Francisco, CA leaves at 7:46 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Columbia, MO to San Francisco, CA leaves at 11:25 PM.
There are 6 buses a day from Columbia, MO to San Francisco, CA which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Columbia, MO to San Francisco, CA, you can count on Greyhound for the best way to get you to San Francisco, CA. You can also check all possible bus companies who offer a service between Columbia, MO and San Francisco, CA and compare the amenities they offer before buying a bus ticket.
A trip to San Francisco, CA from Columbia, MO is worth doing but not as a day trip with a journey time of 47h 45m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Columbia, MO to San Francisco, CA is March.
It's helpful to compare your options as there are 2 ways to travel between Columbia, MO and San Francisco, CA including taking a bus and flight.
Yes, there are bathrooms on board the bus from Columbia, MO to San Francisco, CA for bus company Greyhound.
Yes, the following accessibility options are available when taking the bus from Columbia, MO to San Francisco, CA:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Some of the most interesting sights to explore in San Francisco, CA are:
- Golden Gate Bridge, an iconic suspension bridge offering panoramic views of the San Francisco Bay
- Alcatraz Island, a historic site featuring the infamous former prison and informative audio tours
- Fisherman's Wharf, a bustling waterfront area known for seafood, shops, and sea lions
- Golden Gate Park, a large urban park with gardens, museums, and recreational activities
- Chinatown, the oldest and one of the largest Chinatowns in North America, offering vibrant culture and cuisine.
The best things to do in San Francisco, CA include:
- Ride a cable car through the steep streets of San Francisco for a classic city experience
- Explore the vibrant murals and street art in the Mission District
- Visit the Exploratorium, an interactive science museum perfect for all ages
- Take a scenic walk along the Embarcadero, offering views of the Bay Bridge and access to the Ferry Building Marketplace
- Enjoy a wine tasting tour in nearby Napa Valley, a short drive from the city.
Whether you can cancel your bus ticket from Columbia, MO to San Francisco, CA depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Columbia, MO to San Francisco, CA.
Yes, the following luggage options are included when booking a bus ticket from Columbia, MO to San Francisco, CA:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Columbia, MO to San Francisco, CA:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Columbia, MO to San Francisco, CA.
You can reserve your seat on the bus from Columbia, MO to San Francisco, CA with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Columbia, MO to San Francisco, CA with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Columbia, MO to San Francisco, CA with the following bus company: Greyhound.
Since neither Columbia, MO nor San Francisco, CA are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the bus as it is the most popular way to get from Columbia, MO to San Francisco, CA among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In San Francisco, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like Fisherman's Wharf and Union Square. Common scams include distraction techniques used by groups to steal wallets and fake charity solicitations. It's advisable to avoid poorly lit or isolated areas at night and be wary of unofficial taxi services to ensure safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Columbia, MO to San Francisco, CA
Most Columbia, MO to San Francisco, CA buses use the Columbia, Highway 40 W (Midway Truck Plaza) to San Francisco, Transit Center Bay 29 station pair, with some services arriving at San Francisco, Townsend Street / 5th Street. Use this guide to compare Columbia, MO and San Francisco, CA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Columbia
Arrival bus stations in San Francisco
Columbia, Highway 40 W (Midway Truck Plaza)
City-centre transport
Getting to Columbia, Highway 40 W (Midway Truck Plaza) from Columbia city centre
TrainMissouri River Runner, Lincoln Service Missouri River Runner · 4h 1m · $225
BusGreyhound US0175s · 2h 45m · $24
Columbia, Wabash Bus Station
San Francisco, Transit Center Bay 29
City-centre transport
Getting to San Francisco, Transit Center Bay 29 from San Francisco city centre
Bus397 · 8m · $2
14, 14R · 13m · $2 · every ~30 min
101, 120 · 14m · $6 · every ~9 min
7 · 21m · $2 · every ~10 min
SubwayYellow-N, Green-N, Red-N, Blue-N · 10m · $2 · every ~27 min
San Francisco, Townsend Street / 5th StreetSan Francisco Bus Station,401 Townsend St,94107
City-centre transport
Getting to San Francisco, Townsend Street / 5th Street from San Francisco city centre
BusEast, West · 20m · every ~4 min
Nbus, Nowl · 24m · $2 · every ~2 min
TramN · 23m · $2 · every ~11 min
Most popular bus connections from Columbia, MO
More options for your journey from Columbia, MO to San Francisco, CA
Here are some other resources that might have the information you need
Most popular buses to and from San Francisco, CA and Columbia, MO
Most popular bus connections to San Francisco, CA
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