- Must visit
Columbia Museum Of Art
The city’s leading art museum, known for European, American, Asian, and contemporary works, plus rotating exhibitions and public programs in the downtown arts district.
2,000+ travel companies
2,000+ travel companies
Scan to get our free app
Use our app to get live travel updates and book mobile tickets for trains, buses, flights, and ferries.
App Store
4.942K ratings
Google Play
4.6136K reviews
The cheapest and fastest buses from Indianapolis, IN to Columbia, MO
Showing times and prices for Jun 21
Cheapest price
$66
Average price
$66
Fastest journey
10 h 30 m
Average duration
10 h 30 m
Buses per day
1
Distance
539 km
Cheap tickets
The best way to find a cheap bus ticket from Indianapolis, IN to Columbia, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Indianapolis, IN to Columbia, MO will cost around $66 if you buy it on the day, but the cheapest tickets can be found for only $66.
Fast buses
Of the 1 buses that leave Indianapolis, IN for Columbia, MO on Sun, Jun 21, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Jun 21 the direct buses cover the 539 km distance in an average of 10 h 30 m but if you time it right, some buses will get you there in just 10 h 30 m .
On Sun, Jun 21 the slowest buses will take 10 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
10:00 AM10h30Indianapolis, IN8:30 PMColumbia, MO$661One-way0 transfers
- 10:00 AM10h30Indianapolis, IN8:30 PMColumbia, MO$661One-way0 transfers
Travel Information
Compare bus and flight for Indianapolis, IN to Columbia, MO
Omio recommends booking the flight as it is the most popular option from Indianapolis, IN to Columbia, MO among Omio's users. If you are prioritising price take the bus with prices starting from $50. For those with little time consider booking a flight which can get you there in 6h 26m. The ticket price range depends on the travel mode: a bus costs an average of $50, and a flight costs an average of $283.
Distance: 334 miles (539 km)
Compare bus with
| Bus | Most popular Flight | Driving |
|---|---|---|
$63 Average price Cheapest | $363 Average price | $73 Average price (fuel + tolls) |
12h 58m Average total duration 12h 28m Onboard + 30m Additional time* | 9h 26m Average total duration Fastest 6h 26m Onboard + 3h 0m Additional time* | 5h 26m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Indianapolis, IN to Columbia, MO is a bus with an average price of $63 (€52).
This is compared to other travel options from Indianapolis, IN to Columbia, MO:
A bus is $300 (€245) less than a flight for this route with tickets for a flight from Indianapolis, IN to Columbia, MO costing on average $363 (€297).
The fastest way to travel from Indianapolis, IN to Columbia, MO is by flight with an average journey time of 6h 26m.
Other travel options to Columbia, MO take longer:
Bus takes on average 12h 28m.
It's helpful to compare your options as there are 2 ways to travel between Indianapolis, IN and Columbia, MO including taking a bus and flight.
We recommend using the bus as it is the most popular way to get from Indianapolis, IN to Columbia, MO among Omio's users.
Take the bus. On this route, it's both cheaper and quicker than driving.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Indianapolis, IN to Columbia, MO Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 01:05AM | Arrival Time 04:30PM | Duration 15h25 | Departure days Sat | Cheapest price $75 |
Operator Greyhound USA | Departure Time 05:00AM | Arrival Time 02:30PM | Duration 9h30 | Departure days Wed, Thu, Sat | Cheapest price $109 |
Operator Greyhound | Departure Time 09:00AM | Arrival Time 07:30PM | Duration 10h30 | Departure days Mon | Cheapest price $50 |
Operator Greyhound | Departure Time 10:00AM | Arrival Time 08:30PM | Duration 10h30 | Departure days Fri, Sun | Cheapest price $64 |
Operator Greyhound USA | Departure Time 08:05PM | Arrival Time 10:40AM | Duration 14h35 | Departure days Tue, Wed, Thu, Sat | Cheapest price $109 |
Live departures
Indianapolis, IN to Columbia, MO bus times
The table below shows live departures for Indianapolis, IN to Columbia, MO buses for today, Saturday, June 20. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 8:05 PM Indianapolis, IN | 14h35 | 10:40 AM Columbia, MO | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Indianapolis, IN to Columbia, MO by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Sun
Jun 21
Jun 21
Mon
Jun 22
Jun 22
Tue
Jun 23
Jun 23
Wed
Jun 24
Jun 24
Thu
Jun 25
Jun 25
Fri
Jun 26
Jun 26
Sat
Jun 27
Jun 27
Why should you book Indianapolis, IN to Columbia, MO buses with Omio?
Greyhound operates all buses services from Indianapolis, IN to Columbia, MO.
Omio is an official ticket reseller for all your travel options from Indianapolis, IN to Columbia, MO.
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Indianapolis, IN to Columbia, MO.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Indianapolis, IN to Columbia, MO.
Journey information
Overview: Bus from Indianapolis, IN to Columbia, MO
USAUSA
Buses from Indianapolis, IN to Columbia, MO run on average 5 times per day, taking around 12h 28m. Cheap bus tickets for this journey start at $50 (€41) if you book in advance.
The earliest bus runs at 03:30, the last at 20:35. The fastest bus covers the 334 miles (539 km) distance in 10h 30m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 334 miles (539 km) |
Average bus duration 12h 28m |
Cheapest ticket price $50 (€41) |
Buses per day 5 |
Fastest bus 10h 30m |
First bus 3:30 AM |
Last bus 8:35 PM |
Cheapest Month Jan |
Cheapest Day Wed |
High Season Oct - Dec |
Low Season Jul - Sep |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: Greyhound from Indianapolis, IN to Columbia, MOYou can travel by bus between Indianapolis, IN to Columbia, MO with Greyhound for as low as $50 (€41). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
10h 30m
Cheapest Price
$50 (€41)
Greyhound frequency
4 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Complete guide to Columbia
Things to do in Columbia
Discover the best of Columbia — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Columbia trip today.
- Must visit
South Carolina State Museum
South Carolina’s largest museum, covering art, history, natural history, science, and technology in a large converted mill on the Congaree riverfront.
- Recommended
McKissick Museum
A university museum focusing on Southern culture, folk traditions, and regional history through compact but thoughtful exhibitions on the University of South Carolina campus.
- Must visit
Main Street District
Columbia’s most active downtown corridor, lined with shops, public art, event spaces, and restored buildings. A top area for walking and urban atmosphere.
- Must visit
Riverfront Park
A scenic riverside park with paved walking paths, canal views, industrial heritage features, and some of the city’s most photogenic outdoor scenery.
- Must visit
University Of South Carolina Horseshoe
The historic heart of the university campus, featuring mature trees, brick paths, and some of Columbia’s most graceful academic architecture.
- Gluten-free
South Carolina Barbecue
Slow-smoked pork, often chopped or pulled, traditionally served with the state’s distinctive mustard-based barbecue sauce known as Carolina Gold.
- Gluten-free
Shrimp And Grits
A Lowcountry classic of sautéed shrimp served over creamy grits, reflecting coastal South Carolina cooking and regional seafood traditions.
- Gluten-free
Chicken Bog
A traditional South Carolina one-pot dish of rice, chicken, sausage, and spices, especially associated with central and coastal parts of the state.
Halls Chophouse Columbia
An upscale steakhouse popular for prime steaks, seafood, and Southern hospitality in an elegant dining room.
Motor Supply Company Bistro
A long-running downtown restaurant known for seasonal New American cuisine, polished service, and a lively but refined atmosphere.
Mr. Friendly's New Southern Cafe
An established neighborhood restaurant serving creative Southern fare with a relaxed, intimate atmosphere.
United States Dollar
Costs are moderate by U.S. standards. Casual dining is affordable, while hotels and upscale dining vary by area and season.
Average meal costs
- Budget
- USD 10-15 for fast food or a simple lunch.
- Mid-range
- USD 18-35 per person at a casual restaurant.
- Fine dining
- USD 50+ per person before drinks and tip.
- Coffee
- USD 3-6 for drip coffee or a latte.
Tipping culture
Tip 18-20% at sit-down restaurants before tax. Bars: USD 1-2 per drink. Taxis/rideshares: 10-15% or round up. Hotel housekeeping: USD 2-5 per night. No tip needed for fast food.
FAQs: Bus from Indianapolis, IN to Columbia, MO
Find answers to the most common questions about traveling from Indianapolis, IN to Columbia, MO by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Columbia, MO, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Indianapolis, IN to Columbia, MO can start from as little as $50 (€41) when you book in advance. The average bus ticket price for Indianapolis, IN to Columbia, MO is $63 (€52) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Indianapolis, IN to Columbia, MO is 10h 30m to travel the 334 miles (539 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Indianapolis, IN to Columbia, MO leaves at 3:30 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Indianapolis, IN to Columbia, MO leaves at 8:35 PM.
There are 5 buses a day from Indianapolis, IN to Columbia, MO which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Indianapolis, IN to Columbia, MO, you can count on Greyhound for the best way to get you to Columbia, MO. You can also check all possible bus companies who offer a service between Indianapolis, IN and Columbia, MO and compare the amenities they offer before buying a bus ticket.
A trip to Columbia, MO from Indianapolis, IN is worth doing but not as a day trip with a journey time of 10h 30m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Indianapolis, IN to Columbia, MO is January.
It's helpful to compare your options as there are 2 ways to travel between Indianapolis, IN and Columbia, MO including taking a bus and flight.
Yes, there are bathrooms on board the bus from Indianapolis, IN to Columbia, MO for bus company Greyhound.
Yes, the following accessibility options are available when taking the bus from Indianapolis, IN to Columbia, MO:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Whether you can cancel your bus ticket from Indianapolis, IN to Columbia, MO depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Indianapolis, IN to Columbia, MO.
Yes, the following luggage options are included when booking a bus ticket from Indianapolis, IN to Columbia, MO:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Indianapolis, IN to Columbia, MO:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Indianapolis, IN to Columbia, MO.
You can reserve your seat on the bus from Indianapolis, IN to Columbia, MO with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Indianapolis, IN to Columbia, MO with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Indianapolis, IN to Columbia, MO with the following bus company: Greyhound.
Since neither Indianapolis, IN nor Columbia, MO are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the bus as it is the most popular way to get from Indianapolis, IN to Columbia, MO among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Columbia, MO, travelers should be cautious of petty theft and vehicle break-ins, especially in busy areas and parking lots. Common scams include overcharging by unofficial taxi or ride-share services and fake ticket sellers near popular events. Staying aware of surroundings and using authorized transportation options helps ensure safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Indianapolis, IN to Columbia, MO
Indianapolis
Columbia
The major bus station for departures in Indianapolis is Indianapolis, Illinois St (Greyhound Bus Station). Find all the information you need to know about services, amenities and connections at Indianapolis, Illinois St (Greyhound Bus Station) for your trip from Indianapolis to Columbia.
Indianapolis, Illinois St (Greyhound Bus Station)
information
Indianapolis, E Washington St / N Delaware St (City/County Building)
information
The major bus station for arrivals in Columbia is Columbia, Highway 40 W (Midway Truck Plaza). Find all the information you need to know about services, amenities and connections at Columbia, Highway 40 W (Midway Truck Plaza) for your trip to Columbia from Indianapolis.
Columbia, Highway 40 W (Midway Truck Plaza)
information
Columbia, Wabash Bus Station
information
Most popular bus connections from Indianapolis, IN
More options for your journey from Indianapolis, IN to Columbia, MO
Here are some other resources that might have the information you need
Most popular buses to and from Columbia, MO and Indianapolis, IN
Most popular bus connections to Columbia, MO
The Omio App Makes Travel Planning Easy
We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.
