The cheapest and fastest buses from Columbia, MO to New Orleans, LA
Cheapest price
$427
Average price
$427
Fastest journey
20 h 55 m
Average duration
20 h 55 m
Buses per day
1
Distance
1022 km
The best way to find a cheap bus ticket from Columbia, MO to New Orleans, LA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Columbia, MO to New Orleans, LA will cost around $427 if you buy it on the day, but the cheapest tickets can be found for only $427.
It's difficult to get from Columbia, MO to New Orleans, LA without transferring at least 2 times.


Live departures
Columbia, MO to New Orleans, LA bus times
The table below shows live departures for Columbia, MO to New Orleans, LA buses for today, Thursday, November 6. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 8:05 PM Columbia, MO | 20h55 | 5:00 PM New Orleans, LA | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Columbia, MO to New Orleans, LA by bus
Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Nov 13
Journey information
Overview: Bus from Columbia, MO to New Orleans, LA
Distance 635 miles (1022 km) |
Average bus duration 17h 30m |
Cheapest ticket price $430 (€352) |
Buses per day 4 |
Fastest bus 20h 55m |
First bus 06:10 |
Last bus 23:35 |
Key Takeaways
Train Ticket Prices
- Budget Options: Train tickets from Columbia, MO to New Orleans, LA start from as low as $430 (€352) if booked well in advance.
- Standard Fares: Typically, trains cost $430 (€352) depending on the train type and class.
Bus providers: Greyhound from Columbia, MO to New Orleans, LAYou can travel by bus between Columbia, MO to New Orleans, LA with Greyhound for as low as $430 (€352). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from Columbia, MO to New Orleans, LA
Find answers to the most common questions about traveling from Columbia, MO to New Orleans, LA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at New Orleans, LA, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- French Quarter, a historic district known for its vibrant nightlife, colorful buildings, and rich cultural heritage
- Jackson Square, a historic park in the heart of the French Quarter surrounded by iconic landmarks and street performers
- St. Louis Cathedral, a stunning example of French Gothic architecture and the oldest continuously active Roman Catholic cathedral in the United States
- Garden District, a picturesque neighborhood famous for its well-preserved antebellum mansions and lush gardens
- National WWII Museum, an extensive museum offering immersive exhibits and artifacts detailing the American experience in World War II.
- Preservation Hall, enjoy traditional New Orleans jazz performances in an intimate and historic setting
- Audubon Park, relax in this beautiful urban park featuring walking paths, a zoo, and a golf course
- Frenchmen Street, experience the vibrant music scene with live performances in numerous bars and clubs
- Steamboat Natchez, take a scenic cruise along the Mississippi River on an authentic paddlewheel steamboat
- City Park, explore this expansive park with botanical gardens, an art museum, and outdoor activities.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
To find the cheapest bus tickets for your trip from Columbia, MO to New Orleans, LA, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Columbia, MO to New Orleans, LA
Most popular bus connections from Columbia, MO
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