- Must visit
Pinacoteca di Brera
Milan’s premier fine-art gallery, known for masterpieces by Raphael, Caravaggio, and Mantegna in the historic Brera district.




Cheapest price
$130
Average price
$175
Fastest journey
12h 50m
Average duration
15h 33m
Buses per day
4
Distance
692 km
Omio recommends booking the flight as it is the most popular option from Brussels to Milan among Omio's users. If you are prioritising price take the bus with prices starting from $36. For those with little time consider booking a flight which can get you there in 3h 19m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.7 - 1.7kg. The ticket price range depends on the travel mode: a bus costs an average of $36, and a train costs an average of $222.
Distance: 433 miles (698 km)
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
$86 Average price Cheapest | $170 Average price | $222 Average price | $263 Average price (fuel + tolls) |
10h 2m Average total duration 9h 32m Onboard + 30m Additional time* | 6h 19m Average total duration Fastest 3h 19m Onboard + 3h 0m Additional time* | 8h 41m Average total duration 8h 11m Onboard + 30m Additional time* | 9h 40m Average total duration (door-to-door) |
0.7 - 1.7kg CO2 emissions Lowest | 2.1 - 4.2kg CO2 emissions | - CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Brussels to Milan:
A bus is $84 (€69) less than a flight for this route with tickets for a flight from Brussels to Milan costing on average $170 (€140).
A bus is $135 (€111) less than a train for this route with tickets for a train from Brussels to Milan costing on average $222 (€182).
Other travel options to Milan take longer:
Train takes on average 8h 11m.
Bus takes on average 9h 32m.
You'll arrive about 8m sooner (9h 32m by bus vs 9h 40m by car) and save roughly $177 (€145) compared to fuel and tolls ($86 (€71) vs $263 (€216)). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by BlaBlaCar Bus, FlixBus, Infobus.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 01:30AM | Arrival Time 07:05PM | Duration 17h35 | Departure days Sat, Sun | Cheapest price $184 |
Operator BlaBlaCar Bus | Departure Time 12:05PM | Arrival Time 05:45AM | Duration 17h40 | Departure days Mon, Thu, Sat, Sun | Cheapest price $90 |
Operator BlaBlaCar Bus | Departure Time 02:20PM | Arrival Time 08:00AM | Duration 17h40 | Departure days Mon, Tue, Wed, Thu, Sat, Sun | Cheapest price $127 |
Operator FlixBus | Departure Time 03:10PM | Arrival Time 07:40AM | Duration 16h30 | Departure days Tue, Wed, Thu, Sat, Sun | Cheapest price $134 |
Operator FlixBus | Departure Time 03:40PM | Arrival Time 09:35AM | Duration 17h55 | Departure days Sat | Cheapest price $190 |
Operator FlixBus | Departure Time 04:40PM | Arrival Time 10:40AM | Duration 18h00 | Departure days Mon, Wed, Thu, Sat, Sun | Cheapest price $166 |
Operator BlaBlaCar Bus | Departure Time 07:05PM | Arrival Time 12:30PM | Duration 17h25 | Departure days Everyday | Cheapest price $95 |
Operator FlixBus | Departure Time 08:15PM | Arrival Time 02:25PM | Duration 18h10 | Departure days Fri | Cheapest price $247 |
Operator BlaBlaCar Bus | Departure Time 08:40PM | Arrival Time 09:30AM | Duration 12h50 | Departure days Everyday | Cheapest price $97 |
Operator FlixBus | Departure Time 10:30PM | Arrival Time 04:05PM | Duration 17h35 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $117 |
Operator BlaBlaCar Bus | Departure Time 11:35PM | Arrival Time 01:10PM | Duration 13h35 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $97 |
The table below shows live departures for Brussels to Milan buses for today, Friday, July 10. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 8:15 PM Brussels, Brussels South (Gare du Midi) | 18h10 | 2:25 PM Milano, Autostazione Lampugnano | 1 transfer | |
4740 | 8:40 PM Brussels, Brussels South (Gare du Midi) | 12h50 | 9:30 AM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus · FlixBus | 10:30 PM Brussels, Brussels South (Gare du Midi) | 17h35 | 4:05 PM Milano, Autostazione Lampugnano | 1 transfer | |
4744 | 11:35 PM Brussels, Brussels South (Gare du Midi) | 13h35 | 1:10 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
| Saturday, July 11 | |||||
FlixBus · FlixBus | 1:30 AM Brussels, Brussels South (Gare du Midi) | 17h35 | 7:05 PM Milano, Autostazione Lampugnano | 1 transfer | |
50310 · 57201 | 12:05 PM Brussels, Brussels South (Gare du Midi) | 17h40 | 5:45 AM Milano, Autostazione Lampugnano | 1 transfer | |
50332 · 4781 | 2:20 PM Brussels, Brussels South (Gare du Midi) | 17h40 | 8:00 AM Milano, Autostazione Lampugnano | 1 transfer | |
FlixBus · FlixBus | 3:10 PM Brussels, Brussels South (Gare du Midi) | 16h30 | 7:40 AM Milano, Autostazione Lampugnano | 1 transfer | |
FlixBus · FlixBus · FlixBus | 3:40 PM Brussels, Brussels South (Gare du Midi) | 17h55 | 9:35 AM Milano, Autostazione Lampugnano | 2 transfers | |
FlixBus · FlixBus | 4:40 PM Brussels, Brussels South (Gare du Midi) | 18h00 | 10:40 AM Milano, Autostazione Lampugnano | 1 transfer | |
50338 · 5709 | 7:05 PM Brussels, Brussels South (Gare du Midi) | 17h25 | 12:30 PM Milano, Autostazione Lampugnano | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Brussels to Milan run on average 8 times per day, taking around 9h 32m. Cheap bus tickets for this journey start at $36 (€30) but you can travel from only $24 (€20) by flight.
There are 2 buses per day. The earliest bus runs at 00:15, the last at 23:55. The fastest bus covers the 433 miles (698 km) distance in 12h 50m.
Distance 433 miles (698 km) |
Average bus duration 9h 32m |
Cheapest ticket price $36 (€30) |
Buses per day 8 |
Direct buses 2 |
Fastest bus 12h 50m |
First bus 12:15 AM |
Last bus 11:55 PM |
Cheapest Month Sep |
Cheapest Day Sat |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Sun |
Least Busy Day Sat |
Best time to book 63 days |
Discover the best of Milan — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Milan trip today.
Milan’s premier fine-art gallery, known for masterpieces by Raphael, Caravaggio, and Mantegna in the historic Brera district.
A leading museum of 20th-century Italian art facing Piazza del Duomo, with strong Futurist and modern collections.
A major design-forward museum for world cultures and blockbuster temporary exhibitions in the Tortona area.
Milan’s canal district, loved for waterside walks, lively atmosphere, and photogenic bridges and alleys.
A charming central neighborhood with elegant streets, galleries, boutiques, and a classic Milan atmosphere.
Milan’s main square and symbolic heart, framed by the cathedral, museums, and major historic buildings.
Creamy saffron risotto, one of Milan’s signature dishes, prized for its rich color and elegant flavor.
Braised veal shank, often served with risotto alla Milanese, a classic celebratory dish from Milanese cuisine.
Breaded veal cutlet fried until golden, a famous Milan specialty often compared with schnitzel but traditionally thicker.
Legendary casual stop near the Duomo, famous for panzerotti and a beloved institution for quick, affordable bites.
Well-known modern Milanese restaurant near Porta Nuova, celebrated for refined local classics in a stylish setting.
Historic trattoria serving traditional Milanese and Lombard dishes in an old-fashioned, atmospheric dining room.
Prices are high by Italian standards, especially for hotels and central dining, though transit and casual food stay manageable.
Tipping is modest. Service may be included. Round up or leave EUR 1-2 for coffee, 5-10% at restaurants for good service, and round up taxi fares.
Official public transport app
Orio al Serio Milan Bergamo Airport Bus Station, Bergamo -> Milano Centrale, Milan
Find answers to the most common questions about traveling from Brussels to Milan by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Milan, this guide helps you travel smarter and with confidence.

Most Brussels to Milan buses use the Brussels, Brussels South (Gare du Midi) to Milano, Autostazione Lampugnano station pair, with some services arriving at Milano, Aeroporto di Milano Linate. Use this guide to compare Brussels and Milan bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Brussels, Brussels South (Gare du Midi) is 2 km from Brussels city centre. Public transport options include:
Brussels, Brussels South (Gare du Midi) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Midi (in the station), Belgian Bites (in the station), Fritland Express (0.5 km).
Free Wi-Fi. ATMs are located near the main entrance and throughout the station.
Ticket office support is available at Brussels, Brussels South (Gare du Midi).
Available at Brussels, Brussels South (Gare du Midi): Parking, Taxis, WC.
Accessibility facilities are available at Brussels, Brussels South (Gare du Midi): Elevators, ramps.
Brussels-Noord is 1 km from Brussels city centre. Public transport options include:
Brussels-Noord has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Noord (in the station), Quick Brussels Noord (in the station), Le Pain Quotidien (0.5 km).
Free Wi-Fi. ATMs are located near the main entrance and in the waiting area.
Ticket office support is available at Brussels-Noord.
Available at Brussels-Noord: Parking, Taxis, WC.
Accessibility facilities are available at Brussels-Noord: Elevators, ramps.
Milano, Autostazione Lampugnano is 5 km from Milan city centre. Public transport options include:
Milano, Autostazione Lampugnano has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Lampugnano (in the station), Trattoria Milano (0.5 km), Pizza Express (0.7 km).
Free Wi-Fi. ATMs are located near the main entrance.
Ticket office support is available at Milano, Autostazione Lampugnano.
Available at Milano, Autostazione Lampugnano: Parking, Taxis, WC.
Accessibility facilities are available at Milano, Autostazione Lampugnano: Elevators, ramps.
Milano, San Donato - Settore B (Viale Giuseppe Impastato) is 6 km from Milan city centre. Public transport options include:
Milano, San Donato - Settore B (Viale Giuseppe Impastato) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Italiana (in the station), Fast Food Express (in the station), Trattoria Milano (0.5 km).
Free Wi-Fi. ATMs are located near the main entrance for cash withdrawals.
Ticket office support is available at Milano, San Donato - Settore B (Viale Giuseppe Impastato).
Available at Milano, San Donato - Settore B (Viale Giuseppe Impastato): Parking, Taxis, WC.
Accessibility facilities are available at Milano, San Donato - Settore B (Viale Giuseppe Impastato): Elevators, ramps.
Here are some other resources that might have the information you need