- Must visit
Vatican Museums
One of the world’s greatest museum complexes, known for classical sculpture, Renaissance masterpieces, and the Sistine Chapel. Advance booking is strongly recommended due to very high demand.
Cheapest price
$179
Average price
$238
Fastest journey
1 d 1 h 10 m
Average duration
1 d 3 h 18 m
Buses per day
12
Distance
1174 km
The best way to find a cheap bus ticket from Brussels to Rome is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Brussels to Rome will cost around $238 if you buy it on the day, but the cheapest tickets can be found for only $179.
It's difficult to get from Brussels to Rome without transferring at least once.
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus · FlixBus
50338 · 4787
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus · FlixBus
50338 · 4787
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus · FlixBusOmio recommends booking the flight as it is the most popular option from Brussels to Rome among Omio's users. If you are prioritising price take the bus with prices starting from $99. For those with little time consider booking a flight which can get you there in 2h 58m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.4 - 1.1kg. The ticket price range depends on the travel mode: a bus costs an average of $99, and a train costs an average of $535.
Distance: 729 miles (1174 km)
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
$150 Average price Cheapest | $172 Average price | $535 Average price | $422 Average price (fuel + tolls) |
26h 59m Average total duration 26h 29m Onboard + 30m Additional time* | 5h 58m Average total duration Fastest 2h 58m Onboard + 3h 0m Additional time* | 18h 33m Average total duration 18h 3m Onboard + 30m Additional time* | 15h 33m Average total duration (door-to-door) |
1.2 - 2.9kg CO2 emissions | 3.5 - 7.0kg CO2 emissions | 0.4 - 1.1kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Brussels to Rome:
A bus is $23 (€19) less than a flight for this route with tickets for a flight from Brussels to Rome costing on average $172 (€142).
A bus is $385 (€317) less than a train for this route with tickets for a train from Brussels to Rome costing on average $535 (€441).
Other travel options to Rome take longer:
Train takes on average 18h 3m.
Bus takes on average 26h 29m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 03:35AM | Arrival Time 07:40AM | Duration 28h05 | Departure days Sat | Cheapest price $246 |
Operator FlixBus | Departure Time 03:45AM | Arrival Time 07:40AM | Duration 27h55 | Departure days Mon, Tue, Thu | Cheapest price $182 |
Operator FlixBus | Departure Time 04:15AM | Arrival Time 12:15PM | Duration 32h00 | Departure days Tue, Thu, Sat, Sun | Cheapest price $155 |
Operator FlixBus | Departure Time 10:05AM | Arrival Time 04:05PM | Duration 30h00 | Departure days Tue, Thu, Sat | Cheapest price $193 |
Operator FlixBus | Departure Time 11:05AM | Arrival Time 04:05PM | Duration 29h00 | Departure days Tue, Wed, Thu | Cheapest price $206 |
Operator FlixBus | Departure Time 11:40AM | Arrival Time 04:05PM | Duration 28h25 | Departure days Fri, Sat, Sun | Cheapest price $199 |
Operator FlixBus | Departure Time 03:10PM | Arrival Time 06:45PM | Duration 27h35 | Departure days Tue, Wed, Thu, Fri, Sat, Sun | Cheapest price $163 |
Operator FlixBus | Departure Time 03:40PM | Arrival Time 11:00PM | Duration 31h20 | Departure days Everyday | Cheapest price $124 |
Operator FlixBus | Departure Time 03:55PM | Arrival Time 11:00PM | Duration 31h05 | Departure days Wed, Fri, Sun | Cheapest price $141 |
Operator FlixBus | Departure Time 04:15PM | Arrival Time 09:10PM | Duration 28h55 | Departure days Tue, Wed, Thu | Cheapest price $146 |
Operator FlixBus | Departure Time 04:40PM | Arrival Time 08:20PM | Duration 27h40 | Departure days Mon, Fri, Sat, Sun | Cheapest price $175 |
Operator FlixBus | Departure Time 05:40PM | Arrival Time 11:40PM | Duration 30h00 | Departure days Wed | Cheapest price $227 |
Operator RegioJet a.s. | Departure Time 06:30PM | Arrival Time 02:45PM | Duration 44h15 | Departure days Sun | Cheapest price $188 |
Operator FlixBus | Departure Time 06:40PM | Arrival Time 11:25PM | Duration 28h45 | Departure days Tue, Fri | Cheapest price $151 |
Operator BlaBlaCar Bus | Departure Time 07:05PM | Arrival Time 08:15PM | Duration 25h10 | Departure days Mon, Tue, Thu, Fri, Sun | Cheapest price $187 |
Operator FlixBus | Departure Time 08:15PM | Arrival Time 11:25PM | Duration 27h10 | Departure days Mon, Thu, Sat, Sun | Cheapest price $163 |
Operator FlixBus | Departure Time 10:30PM | Arrival Time 06:05AM | Duration 31h35 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price $120 |
The table below shows live departures for Brussels to Rome buses for today, Wednesday, July 1. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus · FlixBus | 5:40 PM Brussels, Brussels South (Gare du Midi) | 30h00 | 11:40 PM Roma, Autostazione Tiburtina | 2 transfers | |
| Thursday, July 2 | |||||
FlixBus · FlixBus | 3:45 AM Brussels, Brussels South (Gare du Midi) | 27h55 | 7:40 AM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus · FlixBus | 4:15 AM Brussels, Brussels South (Gare du Midi) | 32h00 | 12:15 PM Roma, Autostazione (Metro Anagnina) | 2 transfers | |
FlixBus · FlixBus | 10:05 AM Brussels, Gare Du Midi | 30h00 | 4:05 PM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus · FlixBus | 10:05 AM Brussels, Gare Du Midi | 31h45 | 5:50 PM Roma, Autostazione (Metro Anagnina) | 2 transfers | |
FlixBus · FlixBus | 11:05 AM Brussels, Brussels South (Gare du Midi) | 29h00 | 4:05 PM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus · FlixBus | 11:05 AM Brussels, Brussels South (Gare du Midi) | 30h45 | 5:50 PM Roma, Autostazione (Metro Anagnina) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 3:10 PM Brussels, Brussels South (Gare du Midi) | 27h35 | 6:45 PM Roma, Autostazione Tiburtina | 2 transfers | |
FlixBus · FlixBus · FlixBus | 3:40 PM Brussels, Avenue des Magnolias (King Baudouin) | 31h20 | 11:00 PM Roma, Autostazione Tiburtina | 2 transfers | |
FlixBus · FlixBus · FlixBus | 3:40 PM Brussels, Brussels South (Gare du Midi) | 28h40 | 8:20 PM Roma, Autostazione Tiburtina | 2 transfers | |
FlixBus · FlixBus · FlixBus | 4:15 PM Brussels, Brussels South (Gare du Midi) | 28h55 | 9:10 PM Roma, Autostazione Tiburtina | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Brussels to Rome run on average 12 times per day, taking around 26h 29m. Cheap bus tickets for this journey start at $99 (€82) but you can travel from only $31 (€26) by flight.
The earliest bus runs at 00:10, the last at 23:50. The fastest bus covers the 729 miles (1174 km) distance in 25h 10m.
Distance 729 miles (1174 km) |
Average bus duration 26h 29m |
Cheapest ticket price $99 (€82) |
Buses per day 12 |
Fastest bus 25h 10m |
First bus 12:10 AM |
Last bus 11:50 PM |
Cheapest Month Sep |
Cheapest Day Mon |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Mon |
Least Busy Day Wed |
Best time to book 35 days |
Discover the best of Rome — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Rome trip today.
One of the world’s greatest museum complexes, known for classical sculpture, Renaissance masterpieces, and the Sistine Chapel. Advance booking is strongly recommended due to very high demand.
A celebrated villa museum with major works by Bernini, Caravaggio, and Canova, set inside Villa Borghese gardens. Timed-entry tickets are required and usually need advance reservation.
The city’s historic civic museums on Capitoline Hill, featuring Roman bronzes, sculpture, paintings, and superb views over the Forum area.
A grand Baroque square lined with fountains, churches, and elegant facades. It remains one of Rome’s classic walking and people-watching spots.
A famous monumental staircase linking Piazza di Spagna with Trinità dei Monti, popular for photos, shopping nearby, and city atmosphere.
A characterful district of narrow lanes, ivy-covered facades, and lively evening atmosphere, widely loved for wandering and street photography.
A classic Roman pasta with Pecorino Romano and black pepper. It is one of the city’s most iconic dishes for its simplicity and bold flavor.
Traditional Roman pasta made with guanciale, egg yolk, Pecorino Romano, and black pepper. It is a defining dish of Rome and should not contain cream.
Pasta with tomato, guanciale, Pecorino Romano, and chili. Though linked with Amatrice, it is a staple on Roman menus and deeply rooted in local cooking.
A historic trattoria near the Pantheon, respected for traditional Roman dishes such as carbonara, amatriciana, and seasonal specialties in an intimate atmosphere.
A celebrated central Rome dining room and delicatessen known for classic Roman pasta, cured meats, and an exceptional wine list in a lively upscale setting.
A famous Trastevere trattoria known for authentic Roman comfort food, including cacio e pepe, meatballs, and artichokes, with a classic casual feel.
Moderate for Western Europe: food and coffee can be reasonable, but hotels and major tourist areas cost more.
Service is often included or modest. Locals may round up or leave EUR 1-2 for coffee, 5-10% for good restaurant service; tips are appreciated, not required.
Official public transport app
Rome, Via Marsala / Viale Enrico De Nicola -> Roma Termini
Find answers to the most common questions about traveling from Brussels to Rome by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.

Most Brussels to Rome buses use the Brussels, Brussels South (Gare du Midi) to Roma, Autostazione Tiburtina station pair, with some services arriving at Roma, Autostazione (Metro Anagnina). Use this guide to compare Brussels and Rome bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Brussels, Brussels South (Gare du Midi) is 2 km from Brussels city centre. Public transport options include:
Brussels, Brussels South (Gare du Midi) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Midi (in the station), Belgian Bites (in the station), Fritland Express (0.5 km).
Free Wi-Fi. ATMs are located near the main entrance and throughout the station.
Ticket office support is available at Brussels, Brussels South (Gare du Midi).
Available at Brussels, Brussels South (Gare du Midi): Parking, Taxis, WC.
Accessibility facilities are available at Brussels, Brussels South (Gare du Midi): Elevators, ramps.
Here are some other resources that might have the information you need