- Must visit
Vatican Museums
World-famous museum complex with the Sistine Chapel, Raphael Rooms, and major classical and Renaissance collections. Timed entry is strongly recommended due to very high demand.
Cheapest price
$48
Average price
$70
Fastest journey
7 h 30 m
Average duration
7 h 46 m
Buses per day
15
Distance
477 km
The best way to find a cheap bus ticket from Brindisi to Rome is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Brindisi to Rome will cost around $70 if you buy it on the day, but the cheapest tickets can be found for only $48.
Of the 15 buses that leave Brindisi for Rome on Fri, Jun 19, 8 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, Jun 19 the direct buses cover the 477 km distance in an average of 7 h 46 m but if you time it right, some buses will get you there in just 7 h 30 m .
On Fri, Jun 19 the slowest buses will take 7 h 55 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus
Regionale 19972+
BUS LP702+
Regionale 21036
1104
1110
107
FlixBus
1120
FlixBus
328 · 334
1108Omio recommends booking the bus as it is the most popular option from Brindisi to Rome among Omio's users. If you are prioritising price take the bus with prices starting from $12. For those with little time consider booking a flight which can get you there in 3h 6m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of $12, and a flight costs an average of $23.
Distance: 296 miles (477 km)
Most popular Bus | Train | Flight |
|---|---|---|
$34 Average price Cheapest | $76 Average price | $125 Average price |
7h 13m Average total duration 6h 43m Onboard + 30m Additional time* | 6h 53m Average total duration 6h 23m Onboard + 30m Additional time* | 6h 6m Average total duration Fastest 3h 6m Onboard + 3h 0m Additional time* |
0.5 - 1.2kg CO2 emissions | 0.1 - 0.4kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Brindisi to Rome:
A bus is $42 (€34) less than a train for this route with tickets for a train from Brindisi to Rome costing on average $76 (€62).
A bus is $91 (€74) less than a flight for this route with tickets for a flight from Brindisi to Rome costing on average $125 (€102).
Other travel options to Rome take longer:
Train takes on average 6h 23m.
Bus takes on average 6h 43m.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Itabus | Departure Time 05:30AM | Arrival Time 01:15PM | Duration 7h45 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $60 |
Operator Marino Autolinee | Departure Time 05:35AM | Arrival Time 01:40PM | Duration 8h05 | Departure days Mon, Tue, Wed, Sat, Sun | Cheapest price $65 |
Operator FlixBus | Departure Time 06:00AM | Arrival Time 02:00PM | Duration 8h00 | Departure days Tue, Wed | Cheapest price $79 |
Operator BlaBlaCar | Departure Time 06:50AM | Arrival Time 12:40PM | Duration 5h50 | Departure days Mon | Cheapest price $50 |
Operator FlixBus | Departure Time 07:20AM | Arrival Time 05:15PM | Duration 9h55 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $57 |
Operator Trenitalia | Departure Time 07:54AM | Arrival Time 09:12PM | Duration 13h18 | Departure days Tue, Wed, Fri, Sat | Cheapest price $53 |
Operator BlaBlaCar | Departure Time 08:00AM | Arrival Time 04:50PM | Duration 8h50 | Departure days Sun | Cheapest price $50 |
Operator BlaBlaCar | Departure Time 08:30AM | Arrival Time 03:20PM | Duration 6h50 | Departure days Tue | Cheapest price $48 |
Operator Itabus | Departure Time 09:05AM | Arrival Time 05:45PM | Duration 8h40 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $66 |
Operator Trenitalia | Departure Time 09:21AM | Arrival Time 08:34PM | Duration 11h13 | Departure days Tue, Wed, Fri, Sat | Cheapest price $74 |
Operator FlixBus | Departure Time 09:55AM | Arrival Time 07:10PM | Duration 9h15 | Departure days Mon, Tue, Wed, Sat | Cheapest price $36 |
Operator BlaBlaCar | Departure Time 10:40AM | Arrival Time 04:20PM | Duration 5h40 | Departure days Mon | Cheapest price $61 |
Operator BlaBlaCar | Departure Time 11:00AM | Arrival Time 04:50PM | Duration 5h50 | Departure days Tue | Cheapest price $55 |
Operator FlixBus | Departure Time 11:05AM | Arrival Time 06:35PM | Duration 7h30 | Departure days Tue, Wed | Cheapest price $36 |
Operator BlaBlaCar | Departure Time 11:10AM | Arrival Time 06:10PM | Duration 7h00 | Departure days Mon | Cheapest price $38 |
Operator Itabus | Departure Time 12:05PM | Arrival Time 08:35PM | Duration 8h30 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $54 |
Operator BlaBlaCar | Departure Time 12:30PM | Arrival Time 07:20PM | Duration 6h50 | Departure days Mon | Cheapest price $53 |
Operator FlixBus | Departure Time 12:40PM | Arrival Time 11:00PM | Duration 10h20 | Departure days Mon, Tue, Wed, Fri | Cheapest price $36 |
Operator Marino Autolinee | Departure Time 01:40PM | Arrival Time 09:30PM | Duration 7h50 | Departure days Fri | Cheapest price $71 |
Operator Itabus | Departure Time 02:40PM | Arrival Time 10:45PM | Duration 8h05 | Departure days Everyday | Cheapest price $54 |
Operator BlaBlaCar | Departure Time 02:50PM | Arrival Time 08:20PM | Duration 5h30 | Departure days Wed | Cheapest price $46 |
Operator BlaBlaCar | Departure Time 03:20PM | Arrival Time 09:00PM | Duration 5h40 | Departure days Mon | Cheapest price $43 |
Operator BlaBlaCar | Departure Time 04:00PM | Arrival Time 10:40PM | Duration 6h40 | Departure days Tue | Cheapest price $48 |
Operator FlixBus | Departure Time 04:20PM | Arrival Time 01:15AM | Duration 8h55 | Departure days Sat, Sun | Cheapest price $55 |
Operator BlaBlaCar | Departure Time 04:30PM | Arrival Time 11:40PM | Duration 7h10 | Departure days Sun | Cheapest price $46 |
Operator BlaBlaCar | Departure Time 04:50PM | Arrival Time 11:40PM | Duration 6h50 | Departure days Sun | Cheapest price $44 |
Operator BlaBlaCar | Departure Time 05:30PM | Arrival Time 12:10AM | Duration 6h40 | Departure days Sun | Cheapest price $47 |
Operator FlixBus | Departure Time 06:15PM | Arrival Time 06:40AM | Duration 12h25 | Departure days Thu | Cheapest price $56 |
Operator Marino Autolinee | Departure Time 08:50PM | Arrival Time 05:30AM | Duration 8h40 | Departure days Everyday | Cheapest price $54 |
Operator FlixBus | Departure Time 09:30PM | Arrival Time 05:20AM | Duration 7h50 | Departure days Tue, Wed, Fri, Sat, Sun | Cheapest price $23 |
Operator Itabus | Departure Time 10:50PM | Arrival Time 06:45AM | Duration 7h55 | Departure days Everyday | Cheapest price $54 |
Operator FlixBus | Departure Time 11:30PM | Arrival Time 07:00AM | Duration 7h30 | Departure days Tue, Wed, Fri, Sat | Cheapest price $57 |
The table below shows live departures for Brindisi to Rome buses for tomorrow, Friday, June 19. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
1120 | 5:30 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 7h45 | 1:15 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus · FlixBus | 7:20 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 9h55 | 5:15 PM Roma, Autostazione (Metro Anagnina) | 1 transfer | |
FlixBus · FlixBus | 7:20 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 10h20 | 5:40 PM Roma, Autostazione Tiburtina | 1 transfer | |
Regionale 19972+ BUS LP702+ Regionale 21036 | 7:54 AM Brindisi station | 13h18 | 9:12 PM Rome Termini | 2 transfers | |
1122 | 9:05 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 8h40 | 5:45 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
Intercity 612+ BUS LP702+ Intercity 702 | 9:21 AM Brindisi station | 11h13 | 8:34 PM Rome Termini | 2 transfers | |
1104 | 12:05 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 8h30 | 8:35 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus · FlixBus | 12:40 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 10h20 | 11:00 PM Roma, Autostazione Tiburtina | 1 transfer | |
328 · 334 | 1:40 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 7h50 | 9:30 PM Roma, Autostazione Tiburtina | 1 transfer | |
1110 | 2:40 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 8h05 | 10:45 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
107 | 8:50 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 8h40 | 5:30 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
107 · 132 | 8:50 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 9h15 | 6:05 AM Ciampino, Aeroporto Internazionale di Roma–Ciampino "G. B. Pastine" | 1 transfer | |
FlixBus | 9:30 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 7h50 | 5:20 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
1108 | 10:50 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 7h55 | 6:45 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 11:30 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 7h30 | 7:00 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Brindisi to Rome run on average 16 times per day, taking around 6h 43m. Cheap bus tickets for this journey start at $12 (€10) if you book in advance.
There are 10 buses per day. The earliest bus runs at 00:25, the last at 23:56. The fastest bus covers the 296 miles (477 km) distance in 7h 25m.
Distance 296 miles (477 km) |
Average bus duration 6h 43m |
Cheapest ticket price $12 (€10) |
Buses per day 16 |
Direct buses 10 |
Fastest bus 7h 25m |
First bus 12:25 AM |
Last bus 11:56 PM |
Cheapest Month Apr |
Cheapest Day Sat |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Fri |
Least Busy Day Thu |
Best time to book 70 days |
Discover the best of Rome — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Rome trip today.
World-famous museum complex with the Sistine Chapel, Raphael Rooms, and major classical and Renaissance collections. Timed entry is strongly recommended due to very high demand.
One of Rome’s finest art museums, known for Bernini sculptures and paintings by Caravaggio and Raphael. Advance reservation is typically required because entry is strictly timed.
The city’s historic civic museums on Capitoline Hill, featuring Roman bronzes, imperial sculpture, and art with views over the Forum.
Elegant Baroque square built on an ancient stadium, lined with fountains, palaces, and lively street life. A classic area for strolling and people-watching.
Atmospheric neighborhood of narrow lanes, ivy-covered buildings, and busy evening streets. Popular with visitors but still one of Rome’s most characteristic areas.
Famous monumental staircase linking Piazza di Spagna and Trinità dei Monti. A highly photographed landmark and social-media favorite.
A classic Roman pasta with pecorino Romano and black pepper. It is one of the city’s most iconic dishes and a benchmark of Roman cooking.
Traditional Roman pasta made with guanciale, egg yolk, pecorino Romano, and black pepper. It is famous for its rich sauce without cream.
A beloved pasta sauce of tomato, guanciale, and pecorino Romano, closely tied to Rome’s culinary identity and served with bucatini or rigatoni.
Rome’s most famous fine-dining restaurant, offering elegant tasting menus, panoramic views, and one of the city’s most prestigious dining experiences.
A historic trattoria near the Pantheon, famous for traditional Roman dishes such as gricia, amatriciana, and seasonal specialties.
A celebrated central Rome venue known for classic Roman pasta, exceptional cured meats, and a refined but lively atmosphere.
Rome is moderate by Western Europe standards: sights are affordable, but central hotels and tourist-area dining cost more.
Service is usually included or modest. Tipping is not required, but rounding up or leaving EUR 1-2 at cafes and 5-10% at restaurants for good service is appreciated.
Official public transport app
Rome, Via Marsala / Viale Enrico De Nicola -> Roma Termini
Brindisi is a port city in Italy near the Adriatic Sea. It has a population of only 87,000 and is considered a small to medium-sized city. The town has a bus station that will take you to the various bus stations in Rome. Although there are buses available in Brindisi that will take you to Rome, you will find that only Frecciargento and FlixBus are the only bus companies. There is only one bus per day with Frecciargento and two with FlixBus. Furthermore, there are no buses with Frecciargento on Sundays. There are about 23 buses, on average, per week from Brindisi to Rome. Of those available, there are about two in the morning and one in the afternoon or night, depending on the day. From Brindisi, you will have the option of a direct bus with no transfers, or one with two transfers, however you will not be able to transfer only once. The most common stops will be Stazione di Taranto and Naples Centrale.
The only bus companies from Brindisi to Rome are FlixBus and Frecciargento. Of these two companies, you are offered a choice between zero transfers or two transfers. The bus with zero transfers is by FlixBus and will run you about 7h 30min. The bus with two transfers by Frecciargento will run you about 9h 30min with two transfers. You will arrive at Stazione di Taranto in 1h after departure and Naples Centrale six hours after departure. The distance from Brindisi to Rome is 296 miles (476 km).
On a daily basis, you will not find that many buses as Brindisi is a smallish town. There are only three during the week including Saturdays, and only two on Saturdays. That means on a weekly basis, you will have about 23 buses. Of the options you have, the bus you take will decide how many stops you have, the length of the travel, and the cost of the travel, as well. The earliest bus from Brindisi is 9:25 a.m. and the latest at 11:30 p.m. It would be prudent to book your ticket well it advance, especially in the summer, when traveling to Rome is very popular.
Departure bus station: Brindisi is a small town,so you will not find many departure bus stations. You must travel to these stations from the location you are located, and be prepared, as some may be a good distance away. With FlixBus, you will leave Brindisi from Via Guiseppe Maria Galanti. To get to Via Guiseppe Maria Galanti using a public bus, you can take Bus 4. Via Guiseppe Maria Galanti is a 2min walk from Via Sant’Angelo (Chiesa). It would be prudent to arrive at the station about 30min in advance in case of any unforeseen circumstances that may arrive. At the bus station, you will have facilities such as public restrooms, food stalls, and Wi-Fi to use.
Arrival bus station: You will be arriving in Rome at the Roma, Autostazione Tiburtina with FlixBus and Rome Termini with Frecciarento. The bus station you arrive it will naturally be based on the bus you decide to take in the beginning. When you reach the arriving bus station, you will have public restrooms, refreshments, and Wi-Fi.
The companies that travel from Brindisi to Rome are only two. There is FlixBus and Frecciarento, also known, as Trenitalia. The bus company you choose will decide the changes you have, the price, the indirect or direct nature, and the time it takes. Frecciarento is a bus company that serves all of Italy. It is also a large train company, as well. Only FlixBus offers direct and Trenitalia offers an option with two transfers.
Out of the two options available to you, FlixBus only offers direct routes. It offers two buses per day, one in the morning and one at night, and 14 per week including Sundays. FlixBus is a little bit costlier than the other option and can be up to 15% to 30% more expensive. The schedule for FlixBus is the same each day, with one bus leaving at 9:25 a.m. and another at 11:30 p.m. This includes Sundays, as well. During the holidays, there will naturally be fewer buses offered because of the slow down. It is important to book your bus early and save a spot because of the high demand. With FlixBus, you will not have additional stops and the journey will be about 7h 30min long. The ticket for this bus can be refunded up to 30 days before departure, and if you would like to refund the ticket after, there will be a small fee. Apart from a refund, tickets can be exchanged for a coupon that is valid for 12 months.
Trenitalia is the other option that you may take other than FlixBus. This option is only offered once per day at 11:00 a.m. in the morning. The bus which is offered at 11:00 a.m. is less expensive than FlixBus. During the holidays, the offering of this bus comes to a halt, and there will not be any available options so it is important to consider this and time your journey in advance. Trenitalia will take 9h 30min including the transfers and your only option in terms of bus station is Brindis Regionale.
FlixBus and Trenitalia offer numerous services onboard their buses. Not only is there luggage storage when onboarding, but there is also Wi-Fi, pet allowances, and bike allowances. Luggage will be stored in the compartment outside the bus underneath the sitting area before entering the bus. Wi-Fi is free for all passengers but you may need to sign into the Trenitalia or FlixBus network before accessing. Pets are allowed to a certain size and must be kept in their crates during the length of the trip. You may also want to reserve a spot in advance for your pet. If you have a disability, then please tell FlixBus or Trenitalia in advance and an employee will assist you in anything that you may need. There is also disability seating in the front of the bus for passengers with limited mobility.
Find answers to the most common questions about traveling from Brindisi to Rome by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.

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