- Must visit
Vatican Museums
World-famous papal museums with the Sistine Chapel, Raphael Rooms, and major classical collections.
Cheapest price on Sep 18
€15
Average ticket price on Sep 18
€30
Fastest journey on Sep 18
7 h 25 m
Average journey duration on Sep 18
7 h 46 m
Buses on Sep 18
15
Distance
477 km
The best way to find a cheap bus ticket from Brindisi to Rome is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Brindisi to Rome will cost around €30 if you buy it on the day, but the cheapest tickets can be found for only €15.
On Fri, Sep 18, we found 15 buses from Brindisi to Rome, including 11 direct services.
On Fri, Sep 18 the direct buses cover the 477 km distance in an average of 7 h 46 m but if you time it right, some buses will get you there in just 7 h 25 m .
On Fri, Sep 18 the slowest buses will take 8 h and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
1110
1104
FlixBus
1122
1120
FlixBus
1120
FlixBus
328 · 334
FlixBus · FlixBusOmio recommends booking the bus as it is the most popular option from Brindisi to Rome among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €38 For those with little time, consider booking a flight, which has an average total journey time of 4h 21m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.1 - 0.4kg. Average ticket prices depend on the travel mode: a bus costs an average of €38, while a flight costs an average of €299.
Distance: 296 miles (477 km)
Most popular Bus | Train | Flight |
|---|---|---|
€38 Average price Cheapest | €59 Average price | €299 Average price |
8h 39m Average total duration 8h 9m Onboard + 30m Additional time* | 8h 0m Average total duration 7h 30m Onboard + 30m Additional time* | 4h 21m Average total duration Fastest 2h 21m Onboard + 2h 0m Additional time* |
0.5 - 1.2kg CO2 emissions | 0.1 - 0.4kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Brindisi to Rome:
A bus is €21 less than a train for this route with tickets for a train from Brindisi to Rome costing on average €59.
A bus is €261 less than a flight for this route with tickets for a flight from Brindisi to Rome costing on average €299.
Other travel options to Rome take longer:
Train takes on average 7h 30m.
Bus takes on average 8h 9m.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Itabus | Departure Time 05:30AM | Arrival Time 01:15PM | Duration 7h45 | Departure days Everyday | Cheapest price €14 |
Operator Marino Autolinee | Departure Time 05:35AM | Arrival Time 01:40PM | Duration 8h05 | Departure days Everyday | Cheapest price €22 |
Operator FlixBus | Departure Time 06:00AM | Arrival Time 02:00PM | Duration 8h00 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price €37 |
Operator FlixBus | Departure Time 06:15AM | Arrival Time 03:55PM | Duration 9h40 | Departure days Sat, Sun | Cheapest price €38 |
Operator BlaBlaCar | Departure Time 07:00AM | Arrival Time 01:10PM | Duration 6h10 | Departure days Mon | Cheapest price €37 |
Operator FlixBus | Departure Time 07:20AM | Arrival Time 05:15PM | Duration 9h55 | Departure days Everyday | Cheapest price €18 |
Operator BlaBlaCar | Departure Time 08:00AM | Arrival Time 01:20PM | Duration 5h20 | Departure days Sun | Cheapest price €37 |
Operator BlaBlaCar | Departure Time 08:30AM | Arrival Time 03:10PM | Duration 6h40 | Departure days Tue | Cheapest price €50 |
Operator Itabus | Departure Time 09:05AM | Arrival Time 05:45PM | Duration 8h40 | Departure days Everyday | Cheapest price €15 |
Operator BlaBlaCar | Departure Time 09:20AM | Arrival Time 04:10PM | Duration 6h50 | Departure days Tue | Cheapest price €35 |
Operator FlixBus | Departure Time 09:55AM | Arrival Time 05:20PM | Duration 7h25 | Departure days Everyday | Cheapest price €23 |
Operator BlaBlaCar | Departure Time 10:00AM | Arrival Time 05:00PM | Duration 7h00 | Departure days Thu, Sat | Cheapest price €46 |
Operator BlaBlaCar | Departure Time 10:30AM | Arrival Time 04:00PM | Duration 5h30 | Departure days Tue | Cheapest price €35 |
Operator FlixBus | Departure Time 10:35AM | Arrival Time 07:00PM | Duration 8h25 | Departure days Everyday | Cheapest price €20 |
Operator BlaBlaCar | Departure Time 11:40AM | Arrival Time 05:20PM | Duration 5h40 | Departure days Sun | Cheapest price €36 |
Operator Itabus | Departure Time 12:05PM | Arrival Time 08:25PM | Duration 8h20 | Departure days Everyday | Cheapest price €14 |
Operator FlixBus | Departure Time 12:40PM | Arrival Time 08:45PM | Duration 8h05 | Departure days Everyday | Cheapest price €21 |
Operator BlaBlaCar | Departure Time 01:10PM | Arrival Time 06:50PM | Duration 5h40 | Departure days Tue | Cheapest price €37 |
Operator Marino Autolinee | Departure Time 01:40PM | Arrival Time 09:30PM | Duration 7h50 | Departure days Fri, Sun | Cheapest price €50 |
Operator BlaBlaCar | Departure Time 02:10PM | Arrival Time 07:50PM | Duration 5h40 | Departure days Sun | Cheapest price €37 |
Operator BlaBlaCar | Departure Time 02:30PM | Arrival Time 10:20PM | Duration 7h50 | Departure days Thu | Cheapest price €53 |
Operator Itabus | Departure Time 02:40PM | Arrival Time 10:45PM | Duration 8h05 | Departure days Thu, Fri, Sat, Sun | Cheapest price €15 |
Operator BlaBlaCar | Departure Time 03:30PM | Arrival Time 10:00PM | Duration 6h30 | Departure days Fri | Cheapest price €27 |
Operator FlixBus | Departure Time 04:20PM | Arrival Time 01:15AM | Duration 8h55 | Departure days Sat, Sun | Cheapest price €36 |
Operator BlaBlaCar | Departure Time 05:00PM | Arrival Time 11:40PM | Duration 6h40 | Departure days Sun | Cheapest price €41 |
Operator BlaBlaCar | Departure Time 06:20PM | Arrival Time 12:00AM | Duration 5h40 | Departure days Mon | Cheapest price €45 |
Operator Marino Autolinee | Departure Time 08:50PM | Arrival Time 06:05AM | Duration 9h15 | Departure days Everyday | Cheapest price €26 |
Operator FlixBus | Departure Time 09:30PM | Arrival Time 05:20AM | Duration 7h50 | Departure days Everyday | Cheapest price €20 |
Operator BlaBlaCar | Departure Time 09:40PM | Arrival Time 04:10AM | Duration 6h30 | Departure days Sun | Cheapest price €36 |
Operator Itabus | Departure Time 10:50PM | Arrival Time 06:55AM | Duration 8h05 | Departure days Everyday | Cheapest price €15 |
Operator FlixBus | Departure Time 11:30PM | Arrival Time 07:00AM | Duration 7h30 | Departure days Mon, Tue, Wed, Thu, Sat, Sun | Cheapest price €22 |
The table below shows live departures for Brindisi to Rome buses for today, Thursday, September 17. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus | 9:55 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 7h25 | 5:20 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 10:35 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 8h25 | 7:00 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
1104 | 12:05 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 8h20 | 8:25 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 12:40 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 8h05 | 8:45 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
1110 | 2:40 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 8h05 | 10:45 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
107 | 8:50 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 8h40 | 5:30 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 9:30 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 7h50 | 5:20 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
1108 | 10:50 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 8h05 | 6:55 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 11:30 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 7h30 | 7:00 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
| Friday, September 18 | |||||
1120 | 5:30 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 7h45 | 1:15 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
206 | 5:35 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 8h05 | 1:40 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus · FlixBus | 6:00 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 8h00 | 2:00 PM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus | 7:20 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 9h55 | 5:15 PM Roma, Autostazione (Metro Anagnina) | 1 transfer | |
1122 | 9:05 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 8h40 | 5:45 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Brindisi to Rome run on average 13 times per day, taking around 8h 9m. Cheap bus tickets for this journey start at €9 if you book in advance.
There are 11 buses per day. The earliest bus runs at 00:25, the last at 23:56. The fastest bus covers the 296 miles (477 km) distance in 6h 35m.
Distance 296 miles (477 km) |
Average bus duration 8h 9m |
Cheapest ticket price €9 |
Buses per day 13 |
Direct buses 11 |
Fastest bus 6h 35m |
First bus 12:25 AM |
Last bus 11:56 PM |
Cheapest Month Apr |
Cheapest Day Sat |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Fri |
Least Busy Day Thu |
Best time to book 7 days |
Discover the best of Rome — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Rome trip today.
World-famous papal museums with the Sistine Chapel, Raphael Rooms, and major classical collections.
Outstanding ancient sculpture and mosaic museum housed in the Palazzo dei Conservatori and Palazzo Nuovo.
Celebrated villa museum with Bernini sculptures, Caravaggio paintings, and refined garden setting.
Elegant Baroque square with Bernini's fountains, lively atmosphere, and superb people-watching.
Historic square and gathering place at the Spanish Steps, ideal for classic city views and strolls.
Charming cobbled neighborhood filled with ivy-clad lanes, churches, nightlife, and local character.
Classic Roman pasta with guanciale, egg yolk, Pecorino Romano, and black pepper. A city icon known for rich flavor without cream.
Roman pasta with guanciale, tomato, and Pecorino Romano. A traditional Lazio staple tied to shepherd cooking and bold savory flavor.
Pasta with guanciale, Pecorino Romano, and black pepper. Considered one of Rome's oldest pasta dishes and prized for its simplicity.
Three-Michelin-star dining by Niko Romito at Bulgari Hotel Roma, offering refined Italian tasting menus in an elegant setting.
Historic trattoria in Testaccio known for classic Roman pasta and quinto quarto dishes in a lively, traditional setting.
Popular casual spot famed for Roman-style pizzas and fried starters. Bustling atmosphere and a long-standing local reputation.
Moderate for Europe: stays in central Rome are pricey, but transit is cheap and meals range from affordable pizza to costly tourist-area dining.
Service may be included via coperto or servizio. Round up or leave 5-10% at restaurants if service is good; round up in taxis; small change is fine at cafés.
Official public transport app
Via Marsala, Rome -> Piazza Barberini, Rome
Brindisi is a port city in Italy near the Adriatic Sea. It has a population of only 87,000 and is considered a small to medium-sized city. The town has a bus station that will take you to the various bus stations in Rome. Although there are buses available in Brindisi that will take you to Rome, you will find that only Frecciargento and FlixBus are the only bus companies. There is only one bus per day with Frecciargento and two with FlixBus. Furthermore, there are no buses with Frecciargento on Sundays. There are about 23 buses, on average, per week from Brindisi to Rome. Of those available, there are about two in the morning and one in the afternoon or night, depending on the day. From Brindisi, you will have the option of a direct bus with no transfers, or one with two transfers, however you will not be able to transfer only once. The most common stops will be Stazione di Taranto and Naples Centrale.
The only bus companies from Brindisi to Rome are FlixBus and Frecciargento. Of these two companies, you are offered a choice between zero transfers or two transfers. The bus with zero transfers is by FlixBus and will run you about 7h 30min. The bus with two transfers by Frecciargento will run you about 9h 30min with two transfers. You will arrive at Stazione di Taranto in 1h after departure and Naples Centrale six hours after departure. The distance from Brindisi to Rome is 296 miles (476 km).
On a daily basis, you will not find that many buses as Brindisi is a smallish town. There are only three during the week including Saturdays, and only two on Saturdays. That means on a weekly basis, you will have about 23 buses. Of the options you have, the bus you take will decide how many stops you have, the length of the travel, and the cost of the travel, as well. The earliest bus from Brindisi is 9:25 a.m. and the latest at 11:30 p.m. It would be prudent to book your ticket well it advance, especially in the summer, when traveling to Rome is very popular.
Departure bus station: Brindisi is a small town,so you will not find many departure bus stations. You must travel to these stations from the location you are located, and be prepared, as some may be a good distance away. With FlixBus, you will leave Brindisi from Via Guiseppe Maria Galanti. To get to Via Guiseppe Maria Galanti using a public bus, you can take Bus 4. Via Guiseppe Maria Galanti is a 2min walk from Via Sant’Angelo (Chiesa). It would be prudent to arrive at the station about 30min in advance in case of any unforeseen circumstances that may arrive. At the bus station, you will have facilities such as public restrooms, food stalls, and Wi-Fi to use.
Arrival bus station: You will be arriving in Rome at the Roma, Autostazione Tiburtina with FlixBus and Rome Termini with Frecciarento. The bus station you arrive it will naturally be based on the bus you decide to take in the beginning. When you reach the arriving bus station, you will have public restrooms, refreshments, and Wi-Fi.
The companies that travel from Brindisi to Rome are only two. There is FlixBus and Frecciarento, also known, as Trenitalia. The bus company you choose will decide the changes you have, the price, the indirect or direct nature, and the time it takes. Frecciarento is a bus company that serves all of Italy. It is also a large train company, as well. Only FlixBus offers direct and Trenitalia offers an option with two transfers.
Out of the two options available to you, FlixBus only offers direct routes. It offers two buses per day, one in the morning and one at night, and 14 per week including Sundays. FlixBus is a little bit costlier than the other option and can be up to 15% to 30% more expensive. The schedule for FlixBus is the same each day, with one bus leaving at 9:25 a.m. and another at 11:30 p.m. This includes Sundays, as well. During the holidays, there will naturally be fewer buses offered because of the slow down. It is important to book your bus early and save a spot because of the high demand. With FlixBus, you will not have additional stops and the journey will be about 7h 30min long. The ticket for this bus can be refunded up to 30 days before departure, and if you would like to refund the ticket after, there will be a small fee. Apart from a refund, tickets can be exchanged for a coupon that is valid for 12 months.
Trenitalia is the other option that you may take other than FlixBus. This option is only offered once per day at 11:00 a.m. in the morning. The bus which is offered at 11:00 a.m. is less expensive than FlixBus. During the holidays, the offering of this bus comes to a halt, and there will not be any available options so it is important to consider this and time your journey in advance. Trenitalia will take 9h 30min including the transfers and your only option in terms of bus station is Brindis Regionale.
FlixBus and Trenitalia offer numerous services onboard their buses. Not only is there luggage storage when onboarding, but there is also Wi-Fi, pet allowances, and bike allowances. Luggage will be stored in the compartment outside the bus underneath the sitting area before entering the bus. Wi-Fi is free for all passengers but you may need to sign into the Trenitalia or FlixBus network before accessing. Pets are allowed to a certain size and must be kept in their crates during the length of the trip. You may also want to reserve a spot in advance for your pet. If you have a disability, then please tell FlixBus or Trenitalia in advance and an employee will assist you in anything that you may need. There is also disability seating in the front of the bus for passengers with limited mobility.
Find answers to the most common questions about traveling from Brindisi to Rome by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.

Most Brindisi to Rome buses use the Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) to Roma, Autostazione Tiburtina station pair, with some services arriving at Roma, Autostazione (Metro Anagnina). Use this guide to compare Brindisi and Rome bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Brindisi has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Cafes and small eateries nearby.
Wi-Fi is available at Brindisi. ATMs are available at Brindisi.
Ticket office support is available at Brindisi.
Available at Brindisi: Parking, Taxis, WC.
Accessibility facilities are available at Brindisi: Wheelchair ramps available.
Roma, Autostazione Tiburtina is 4 km from Rome city centre. Public transport options include:
Roma, Autostazione Tiburtina has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Cafes and vending machines available.
Wi-Fi is available at Roma, Autostazione Tiburtina. ATMs are aTM available near ticket office.
Ticket office support is available at Roma, Autostazione Tiburtina.
Available at Roma, Autostazione Tiburtina: Parking, Taxis, WC.
Accessibility facilities are available at Roma, Autostazione Tiburtina: Wheelchair accessible entrances and facilities.
Here are some other resources that might have the information you need