- Must visit
Palazzo Abatellis - Regional Gallery of Sicily
Major art museum in a Gothic-Catalan palace, known for Sicilian medieval and Renaissance masterpieces including works by Antonello da Messina.
Cheapest price
$97
Average price
$97
Fastest journey
19 h 55 m
Average duration
19 h 55 m
Buses per day
1
Distance
482 km
The best way to find a cheap bus ticket from Brindisi to Palermo is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Brindisi to Palermo will cost around $97 if you buy it on the day, but the cheapest tickets can be found for only $97.
It's difficult to get from Brindisi to Palermo without transferring at least once.
FlixBus · FlixBus
FlixBus · FlixBusOmio recommends booking the flight as it is the most popular option from Brindisi to Palermo among Omio's users. If you are prioritising price take the train with prices starting from $32. For those with little time consider booking a flight which can get you there in 1h 33m. The ticket price range depends on the travel mode: a train costs an average of $32, and a flight costs an average of $129.
Distance: 299 miles (482 km)
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
$103 Average price | $172 Average price | $72 Average price Cheapest | $100 Average price (fuel + tolls) |
11h 50m Average total duration 11h 20m Onboard + 30m Additional time* | 4h 33m Average total duration Fastest 1h 33m Onboard + 3h 0m Additional time* | 15h 32m Average total duration 15h 2m Onboard + 30m Additional time* | 7h 56m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Brindisi to Palermo:
A train is $31 (€25) less than a bus for this route with tickets for a bus from Brindisi to Palermo costing on average $103 (€84).
A train is $100 (€81) less than a flight for this route with tickets for a flight from Brindisi to Palermo costing on average $172 (€140).
Other travel options to Palermo take longer:
Bus takes on average 11h 20m.
Train takes on average 15h 2m.
You'll arrive about -4h -24m sooner (11h 20m by bus vs 7h 56m by car) and save roughly $-2.85 (€-2.33) compared to fuel and tolls ($103 (€84) vs $100 (€82)). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by FlixBus, BlaBlaCar.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 10:40AM | Arrival Time 01:15PM | Duration 26h35 | Departure days Mon | Cheapest price $106 |
Operator FlixBus | Departure Time 11:40AM | Arrival Time 12:55PM | Duration 25h15 | Departure days Mon | Cheapest price $130 |
Operator FlixBus | Departure Time 12:40PM | Arrival Time 03:15PM | Duration 26h35 | Departure days Tue, Wed, Sat, Sun | Cheapest price $101 |
Operator FlixBus | Departure Time 11:30PM | Arrival Time 07:25PM | Duration 19h55 | Departure days Wed, Thu, Fri, Sat, Sun | Cheapest price $71 |
The table below shows live departures for Brindisi to Palermo buses for today, Thursday, June 18. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 11:30 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 19h55 | 7:25 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Brindisi to Palermo run on average 1 times per day, taking around 11h 20m. Cheap bus tickets for this journey start at $49 (€40) but you can travel from only $32 (€26) by train.
The earliest bus runs at 04:21, the last at 23:50. The fastest bus covers the 299 miles (482 km) distance in 25h 15m.
Distance 299 miles (482 km) |
Average bus duration 11h 20m |
Cheapest ticket price $49 (€40) |
Buses per day 1 |
Fastest bus 25h 15m |
First bus 4:21 AM |
Last bus 11:50 PM |
Cheapest Month Jul |
Cheapest Day Tue |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Sun |
Least Busy Day Tue |
Best time to book 5 days |
Discover the best of Palermo — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Palermo trip today.
Major art museum in a Gothic-Catalan palace, known for Sicilian medieval and Renaissance masterpieces including works by Antonello da Messina.
One of Sicily's most important archaeological museums, with Punic, Greek and Roman collections and notable sculpture fragments.
Historic noble residence preserved with original furnishings, offering a vivid look at aristocratic life in Palermo.
Energetic historic district centered on Palermo's most famous street market, full of everyday local life and vivid street scenes.
Striking central square framed by historic buildings and the famous fountain, a key stop in the old town.
One of Palermo's main historic streets, largely pedestrianized and lined with landmarks, shops and lively urban scenes.
Fried rice balls stuffed with ragù, mozzarella, or butter and ham. Palermo is famous for its round arancine and strong street-food tradition.
A classic Palermo street sandwich made with veal spleen and lung, often topped with caciocavallo or ricotta. It is one of the city's most iconic local bites.
Chickpea fritters, usually served in a sesame bread roll. They are a beloved Palermo snack and a staple of the city's historic friggitorie.
Well-regarded restaurant near the historic center serving refined Sicilian cuisine with local ingredients in an elegant but relaxed atmosphere.
Popular central spot for approachable Sicilian cooking, including pasta and regional classics, with a casual and lively atmosphere.
Established seafood-focused trattoria appreciated for traditional Palermo and Sicilian dishes in a classic local dining room.
Moderate by Italian standards: street food is cheap, while central hotels and tourist restaurants cost more.
Service is often included or minimal. Rounding up or leaving EUR 1-2 at cafes is common; about 5-10% for very good restaurant service. Taxis are usually rounded up.
Find answers to the most common questions about traveling from Brindisi to Palermo by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Palermo, this guide helps you travel smarter and with confidence.

Most Brindisi to Palermo buses use the Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) to Palermo, Via Tommaso Fazello (Terminal Bus) station pair. Use this guide to compare Brindisi and Palermo bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need