- Must visit
Antonino Salinas Regional Archaeological Museum
Palermo’s top museum displays Sicilian archaeology, including the famous Punic Stone and Selinunte finds, in a former convent complex.
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The cheapest and fastest buses from Brindisi to Palermo
Showing times, prices and bookable tickets for Sep 17
Cheapest price on Sep 17
$124
Average ticket price on Sep 17
$124
Fastest journey on Sep 17
1 d 2 h 35 m
Average journey duration on Sep 17
1 d 2 h 35 m
Buses on Sep 17
1
Distance
482 km
Cheap tickets
The best way to find a cheap bus ticket from Brindisi to Palermo is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Brindisi to Palermo will cost around $124 if you buy it on the day, but the cheapest tickets can be found for only $124.
Fast buses
It's difficult to get from Brindisi to Palermo without transferring at least once.
FlixBus · FlixBus12:40 PM26h35Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)3:15 PMPalermo, Via Tommaso Fazello (Terminal Bus)$1241One-way1 transfer
- FlixBus · FlixBus12:40 PM26h35Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)3:15 PMPalermo, Via Tommaso Fazello (Terminal Bus)$1241One-way1 transfer
Travel Information
Compare bus, train, and flight for Brindisi to Palermo
Omio recommends booking the flight as it is the most popular option from Brindisi to Palermo among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $107 For those with little time, consider booking a flight, which has an average total journey time of 4h 45m. Average ticket prices depend on the travel mode: a bus costs an average of $107, while a flight costs an average of $270.
Distance: 299 miles (482 km)
Compare bus with
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
$107 Average price Cheapest | $270 Average price | $142 Average price | $101 Average price (fuel + tolls) |
13h 53m Average total duration 13h 23m Onboard + 30m Additional time* | 4h 45m Average total duration Fastest 2h 45m Onboard + 2h 0m Additional time* | 16h 55m Average total duration 16h 25m Onboard + 30m Additional time* | 7h 56m Average total duration (door-to-door) |
Most popular bus company |  Most popular airline |  Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Brindisi to Palermo is a bus with an average price of $107.
This is compared to other travel options from Brindisi to Palermo:
A bus is $35 less than a train for this route with tickets for a train from Brindisi to Palermo costing on average $142.
A bus is $163 less than a flight for this route with tickets for a flight from Brindisi to Palermo costing on average $270.
The fastest way to travel from Brindisi to Palermo is by flight with an average journey time of 2h 45m.
Other travel options to Palermo take longer:
Bus takes on average 13h 23m.
Train takes on average 16h 25m.
It's helpful to compare your options as there are 3 ways to travel between Brindisi and Palermo including taking a bus, train, and flight.
We recommend using the flight as it is the most popular way to get from Brindisi to Palermo among Omio's users.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.
Tickets start at around $107 compared to roughly $101 in fuel and tolls — a saving of about $-5.87. The journey takes 13h 23m versus 7h 56m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Brindisi to Palermo Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:40PM | Arrival Time 03:15PM | Duration 26h35 | Departure days Everyday | Cheapest price $59 |
Live departures
Brindisi to Palermo bus times
The table below shows live departures for Brindisi to Palermo buses for tomorrow, Thursday, September 17. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| FlixBus · FlixBus | 12:40 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 26h35 | 3:15 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Brindisi to Palermo by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Brindisi to Palermo buses with Omio?
FlixBus operates all buses services from Brindisi to Palermo.
Omio is an official ticket reseller for all your travel options from Brindisi to Palermo.
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Brindisi to Palermo.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Brindisi to Palermo.
Journey information
Overview: Bus from Brindisi to Palermo
ItalyItaly
Buses from Brindisi to Palermo run on average 2 times per day, taking around 13h 23m. Cheap bus tickets for this journey start at $51 but you can travel from only $35 by flight.
There are 1 buses per day. The earliest bus runs at 04:21, the last at 23:50. The fastest bus covers the 299 miles (482 km) distance in 11h 30m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $35
Distance 299 miles (482 km) |
Average bus duration 13h 23m |
Cheapest ticket price $51 |
Buses per day 2 |
Direct buses 1 |
Fastest bus 11h 30m |
First bus 4:21 AM |
Last bus 11:50 PM |
Cheapest Month Sep |
Cheapest Day Tue |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Sat |
Least Busy Day Mon |
Best time to book 21 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $35
Bus providers: FlixBus from Brindisi to PalermoYou can travel by bus between Brindisi to Palermo with FlixBus for as low as $35. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
11h 30m
Cheapest FlixBus Price
$51
FlixBus frequency
2 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Complete guide to Palermo
Things to do in Palermo
Discover the best of Palermo — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Palermo trip today.
- Recommended
Palazzo Mirto
Historic rooms and vivid majolica floors showcase aristocratic Palermo. Visit for decorative arts, period interiors and city history.
- Recommended
Steri Museum
Housed in the grand Steri Palace, this museum presents the Sicilian Inquisition’s story through cells, graffiti and historical documents.
- Must visit
Via Vittorio Emanuele
Palermo’s elegant main boulevard links major monuments, shops and theaters. Ideal for first walks and observing the city’s layered architecture.
- Must visit
Via Maqueda
This historic street cuts across the old center and hosts markets, churches and daily life. A lively route for exploring local Palermo.
- Recommended
Albergheria
A bustling old quarter famous for layered street life, churches and market culture. Best explored on foot for atmosphere and urban history.
Arancina
Crisp fried rice ball stuffed with ragù, peas and caciocavallo. A Sicilian street food icon widely loved in Palermo.
Pane con la Milza
Soft sesame-topped bun filled with spleen and lung, often with caciocavallo or ricotta. A classic Palermo street food with deep local roots.
Pasta con le Sarde
Pasta with sardines, wild fennel, pine nuts and raisins. Its sweet-savory flavor reflects Palermo's Arab-Norman culinary heritage.
I Pupi
Refined Michelin-starred restaurant known for creative Sicilian tasting menus in an elegant, intimate setting.
Osteria Ballarò
Historic seafood restaurant near the port, praised for fresh catch, raw dishes and classic Palermo fish recipes.
Nni Franco U Vastiddaru
Legendary no-frills street-food stop celebrated for pane con la milza and authentic local sandwiches loved by residents.
Euro (€)
Moderate for Italy. Street food and local meals are affordable, while hotels in peak season cost more. Public transport is cheap, keeping overall tourist costs reasonable.
Average meal costs
- Budget
- €8-12 for street food or a simple meal.
- Mid-range
- €20-35 per person for a restaurant meal.
- Fine dining
- €60+ per person for upscale dining.
- Coffee
- €1.50-3 for coffee or cappuccino.
Tipping culture
Service is often included or modest. Round up or leave 5-10% for great restaurant service. Taxis are usually rounded up. Small change is fine in cafes.
FAQs: Bus from Brindisi to Palermo
Find answers to the most common questions about traveling from Brindisi to Palermo by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Palermo, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Brindisi to Palermo can start from as little as $51 when you book in advance. The average bus ticket price for Brindisi to Palermo is $107 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Brindisi to Palermo is 11h 30m to travel the 299 miles (482 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Brindisi to Palermo leaves at 4:21 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Brindisi to Palermo leaves at 11:50 PM.
Yes, there are 1 direct buses a day from Brindisi to Palermo with FlixBus, BlaBlaCar. Schedules can vary on holidays or weekends with fewer direct buses.
When taking a bus from Brindisi to Palermo, you can count on FlixBus, BlaBlaCar for the best way to get you to Palermo. You can also check all possible bus companies who offer a service between Brindisi and Palermo and compare the amenities they offer before buying a bus ticket.
Passengers board the bus most frequently from Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale), which is located around away from the city centre, and they get off the bus at Palermo, Via Tommaso Fazello (Terminal Bus), located 1 away from the city centre.
A trip to Palermo from Brindisi is worth doing but not as a day trip with a journey time of 11h 30m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Brindisi to Palermo is September.
It's helpful to compare your options as there are 3 ways to travel between Brindisi and Palermo including taking a bus, train, and flight.
Yes, the following accessibility options are available when taking the bus from Brindisi to Palermo:
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Brindisi to Palermo for bus company FlixBus.
Some of the most interesting sights to explore in Palermo are:
- Palermo Cathedral, a stunning architectural blend of Norman, Moorish, and Baroque styles
- Teatro Massimo, Italy's largest opera house known for its grand performances and impressive acoustics
- Palazzo dei Normanni, a historic palace featuring the exquisite Palatine Chapel with its Byzantine mosaics
- Quattro Canti, a Baroque square at the intersection of Palermo's two main streets, known for its symmetrical fountains and statues
- Orto Botanico di Palermo, a lush botanical garden showcasing diverse plant species.
The best things to do in Palermo include:
- Capuchin Catacombs, an eerie yet fascinating underground cemetery with mummified remains
- Ballarò Market, a bustling street market offering a taste of local Sicilian produce and culture
- Explore the vibrant street art in the Vucciria district
- Take a cooking class to learn how to make traditional Sicilian dishes
- Enjoy a leisurely stroll along the picturesque Foro Italico promenade.
Whether you can cancel your bus ticket from Brindisi to Palermo depends on the bus companies:
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Brindisi to Palermo.
Yes, the following luggage options are included when booking a bus ticket from Brindisi to Palermo:
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Brindisi to Palermo:
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Brindisi to Palermo. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from Brindisi to Palermo with the following bus company: FlixBus
Yes, there are USB plugs on board the bus from Brindisi to Palermo with the following bus company: FlixBus.
Yes, there is Wifi on board the bus from Brindisi to Palermo with the following bus company: FlixBus.
Since both Brindisi and Palermo are in the Schengen Area, a passport is not required for European Union (EU) or Schengen-associated country citizens. A national ID card is sufficient.
We recommend using the flight as it is the most popular way to get from Brindisi to Palermo among Omio's users.
Italy uses the euro (EUR) as its currency. Travelers generally find it convenient to use cards for most payments, especially in cities and larger establishments, but carrying some cash is advisable for small shops, markets, and rural areas where card acceptance may be limited.
In Palermo, travelers should be cautious of petty theft, especially pickpocketing in crowded areas like markets and public transport. Scams include overcharging by taxi drivers and vendors, as well as unofficial guides offering overpriced tours. It's advisable to use authorized services and stay vigilant in busy tourist spots.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Brindisi to Palermo
Most Brindisi to Palermo buses use the Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) to Palermo, Via Tommaso Fazello (Terminal Bus) station pair. Use this guide to compare Brindisi and Palermo bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Brindisi
Arrival bus stations in Palermo
Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)Brindisi Falcone Professional Institute, Via Giuseppe Maria Galanti 8, 72100
Most popular bus connections from Brindisi
More options for your journey from Brindisi to Palermo
Here are some other resources that might have the information you need
Most popular buses to and from Palermo and Brindisi
Most popular bus connections to Palermo
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