- Must visit
Pinacoteca di Brera
One of Italy’s top art museums, featuring masterpieces by Mantegna, Bellini, Raphael, Caravaggio, and Piero della Francesca.
Cheapest price on Sep 18
$43
Average ticket price on Sep 18
$84
Fastest journey on Sep 18
12 h 40 m
Average journey duration on Sep 18
13 h 1 m
Buses on Sep 18
28
Distance
890 km
The best way to find a cheap bus ticket from Brindisi to Milan is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Brindisi to Milan will cost around $84 if you buy it on the day, but the cheapest tickets can be found for only $43.
On Fri, Sep 18, we found 28 buses from Brindisi to Milan, including 8 direct services.
On Fri, Sep 18 the direct buses cover the 890 km distance in an average of 13 h 1 m but if you time it right, some buses will get you there in just 12 h 40 m .
On Fri, Sep 18 the slowest buses will take 13 h 15 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
1104 · 2494
1110 · 2422
1120 · 2400
1110 · 2418
1104 · 3506
042
107 · 101
206 · 200
FlixBus
042Omio recommends booking the flight as it is the most popular option from Brindisi to Milan among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $77 For those with little time, consider booking a flight, which has an average total journey time of 4h 55m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.3 - 0.8kg. Average ticket prices depend on the travel mode: a bus costs an average of $77, while a flight costs an average of $266.
Distance: 553 miles (890 km)
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
$77 Average price Cheapest | $266 Average price | $115 Average price | $287 Average price (fuel + tolls) |
15h 37m Average total duration 15h 7m Onboard + 30m Additional time* | 4h 55m Average total duration Fastest 2h 55m Onboard + 2h 0m Additional time* | 10h 15m Average total duration 9h 45m Onboard + 30m Additional time* | 10h 57m Average total duration (door-to-door) |
0.9 - 2.2kg CO2 emissions | - CO2 emissions | 0.3 - 0.8kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Brindisi to Milan:
A bus is $38 less than a train for this route with tickets for a train from Brindisi to Milan costing on average $115.
A bus is $189 less than a flight for this route with tickets for a flight from Brindisi to Milan costing on average $266.
Other travel options to Milan take longer:
Train takes on average 9h 45m.
Bus takes on average 15h 7m.
Tickets start at around $77 compared to roughly $287 in fuel and tolls — a saving of about $210. The journey takes 15h 7m versus 10h 57m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by Marino Autolinee, FlixBus, Itabus, BlaBlaCar.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Itabus | Departure Time 05:30AM | Arrival Time 11:05PM | Duration 17h35 | Departure days Fri, Sat, Sun | Cheapest price $50 |
Operator Marino Autolinee | Departure Time 05:35AM | Arrival Time 06:40PM | Duration 13h05 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $51 |
Operator FlixBus | Departure Time 06:00AM | Arrival Time 08:50PM | Duration 14h50 | Departure days Mon, Wed, Fri, Sat, Sun | Cheapest price $83 |
Operator BlaBlaCar | Departure Time 07:30AM | Arrival Time 06:10PM | Duration 10h40 | Departure days Tue | Cheapest price $99 |
Operator BlaBlaCar | Departure Time 09:30AM | Arrival Time 08:10PM | Duration 10h40 | Departure days Tue | Cheapest price $93 |
Operator FlixBus | Departure Time 09:55AM | Arrival Time 04:00AM | Duration 18h05 | Departure days Fri | Cheapest price $117 |
Operator FlixBus | Departure Time 10:35AM | Arrival Time 04:00AM | Duration 17h25 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $57 |
Operator BlaBlaCar | Departure Time 12:00PM | Arrival Time 12:30AM | Duration 12h30 | Departure days Sun | Cheapest price $92 |
Operator Itabus | Departure Time 12:05PM | Arrival Time 08:50AM | Duration 20h45 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $27 |
Operator FlixBus | Departure Time 12:40PM | Arrival Time 05:55AM | Duration 17h15 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $40 |
Operator Itabus | Departure Time 02:40PM | Arrival Time 07:40AM | Duration 17h00 | Departure days Fri, Sat, Sun | Cheapest price $35 |
Operator FlixBus | Departure Time 04:20PM | Arrival Time 11:55AM | Duration 19h35 | Departure days Sat, Sun | Cheapest price $74 |
Operator Itabus | Departure Time 04:55PM | Arrival Time 07:35AM | Duration 14h40 | Departure days Fri, Sat, Sun | Cheapest price $49 |
Operator Marino Autolinee | Departure Time 05:45PM | Arrival Time 07:00AM | Duration 13h15 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $39 |
Operator FlixBus | Departure Time 05:55PM | Arrival Time 07:30AM | Duration 13h35 | Departure days Everyday | Cheapest price $35 |
Operator FlixBus | Departure Time 06:15PM | Arrival Time 07:30AM | Duration 13h15 | Departure days Everyday | Cheapest price $83 |
Operator Marino Autolinee | Departure Time 08:50PM | Arrival Time 09:40AM | Duration 12h50 | Departure days Everyday | Cheapest price $39 |
Operator FlixBus | Departure Time 09:30PM | Arrival Time 03:20PM | Duration 17h50 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $49 |
Operator Itabus | Departure Time 10:50PM | Arrival Time 04:40PM | Duration 17h50 | Departure days Everyday | Cheapest price $31 |
Operator FlixBus | Departure Time 11:30PM | Arrival Time 05:10PM | Duration 17h40 | Departure days Mon, Tue, Wed, Thu, Sat, Sun | Cheapest price $58 |
The table below shows live departures for Brindisi to Milan buses for today, Thursday, September 17. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
107 · 101 | 8:50 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 13h30 | 10:20 AM Milano, Autostazione Lampugnano | 1 transfer | |
107 · 101 | 8:50 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 12h50 | 9:40 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 1 transfer | |
FlixBus · FlixBus | 9:30 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 17h50 | 3:20 PM Milano, Autostazione Lampugnano | 1 transfer | |
FlixBus · FlixBus | 9:30 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 17h05 | 2:35 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 1 transfer | |
1108 · 2126 | 10:50 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 17h50 | 4:40 PM Milano, Autostazione Lampugnano | 1 transfer | |
FlixBus · FlixBus | 11:30 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 19h00 | 6:30 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 1 transfer | |
FlixBus · FlixBus | 11:30 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 17h40 | 5:10 PM Milano, Autostazione Lampugnano | 1 transfer | |
| Friday, September 18 | |||||
1120 · 2400 | 5:30 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 17h35 | 11:05 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 1 transfer | |
206 · 200 | 5:35 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 13h05 | 6:40 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 1 transfer | |
206 · 200 | 5:35 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 13h50 | 7:25 PM Milano, Autostazione Lampugnano | 1 transfer | |
FlixBus | 6:00 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 14h50 | 8:50 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus | 6:00 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 14h00 | 8:00 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 0 transfersDirect | |
FlixBus · FlixBus | 9:55 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 18h05 | 4:00 AM Milano, Autostazione Lampugnano | 1 transfer | |
FlixBus · FlixBus | 10:35 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 18h40 | 5:15 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 1 transfer | |
FlixBus · FlixBus · FlixBus | 10:35 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 25h20 | 11:55 AM Milano, Milan Linate Airport | 2 transfers | |
1104 · 3506 | 12:05 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 20h45 | 8:50 AM Milano, Autostazione Lampugnano | 1 transfer | |
1104 · 3898 | 12:05 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 18h05 | 6:10 AM Milano, Autostazione Lampugnano | 1 transfer | |
1104 · 2494 | 12:05 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 18h50 | 6:55 AM Milano, Autostazione Lampugnano | 1 transfer | |
FlixBus · FlixBus | 12:40 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 17h25 | 6:05 AM Milano, Autostazione Lampugnano | 1 transfer | |
FlixBus · FlixBus | 12:40 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 18h40 | 7:20 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 1 transfer | |
1110 · 2422 | 2:40 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 17h00 | 7:40 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 1 transfer | |
1110 · 2418 | 2:40 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 17h30 | 8:10 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 1 transfer | |
2214 | 4:55 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 15h25 | 8:20 AM Milano, Autostazione Lampugnano | 0 transfersDirect | |
2214 | 4:55 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 14h40 | 7:35 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 0 transfersDirect | |
042 | 5:45 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 12h40 | 6:25 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 0 transfersDirect | |
042 | 5:45 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 13h15 | 7:00 AM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus · FlixBus | 5:55 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 14h20 | 8:15 AM Milano, Autostazione Lampugnano | 1 transfer | |
FlixBus · FlixBus | 5:55 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 13h35 | 7:30 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 1 transfer | |
FlixBus | 6:15 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 14h00 | 8:15 AM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus | 6:15 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 13h15 | 7:30 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 0 transfersDirect | |
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Brindisi to Milan run on average 28 times per day, taking around 15h 7m. Cheap bus tickets for this journey start at $2 if you book in advance.
There are 7 buses per day. The earliest bus runs at 00:10, the last at 23:55. The fastest bus covers the 553 miles (890 km) distance in 12h 10m.
Distance 553 miles (890 km) |
Average bus duration 15h 7m |
Cheapest ticket price $2 |
Buses per day 28 |
Direct buses 7 |
Fastest bus 12h 10m |
First bus 12:10 AM |
Last bus 11:55 PM |
Cheapest Month Jul |
Cheapest Day Sat |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Sat |
Least Busy Day Fri |
Best time to book 21 days |
Discover the best of Milan — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Milan trip today.
One of Italy’s top art museums, featuring masterpieces by Mantegna, Bellini, Raphael, Caravaggio, and Piero della Francesca.
This contemporary art museum near Porta Romana presents rotating exhibitions in a striking former industrial distillery complex.
Italy’s leading science museum is set in a former monastery and features Leonardo galleries, trains, aircraft, and a submarine.
Milan’s central square frames the cathedral and major civic buildings, making it the city’s essential meeting point and photo stop.
This artistic district offers charming lanes, Brera atmosphere, boutiques, and easy access to galleries and evening strolls.
A large landscaped park behind the castle, perfect for walks, skyline views, and reaching landmarks like the Arch of Peace.
Saffron risotto cooked with butter, stock and cheese. It is Milan's signature dish, linked to the city's love of rich northern Italian rice cookery.
Breaded veal cutlet fried in butter until golden. A classic Milanese main, prized for its simple preparation and long-standing local tradition.
Slow-braised veal shanks with vegetables, wine and broth, often finished with gremolata. A hearty Lombard specialty commonly paired with risotto.
Three-Michelin-star fine dining by Enrico Bartolini in MUDEC. Expect refined Italian tasting menus in a polished contemporary setting.
Historic Milanese restaurant near the Duomo, famous for risotto and cotoletta. Traditional, elegant rooms and a strong local culinary identity.
Long-running local favorite for classic Milanese cuisine, especially risotto and ossobuco. Warm, old-school atmosphere in the Brera area.
Moderate for Western Europe. Hotels and central dining can be pricey, but transit is affordable and budget meals, aperitivo deals, and local cafes help keep daily costs reasonable.
Tipping is modest. Service may be included. Round up or leave €1-2 at cafes, 5-10% for good restaurant service, and round up taxi fares.
Official public transport app
Orio al Serio, Milan Bergamo Airport (Bus station) -> Milano Centrale, Milan
Find answers to the most common questions about traveling from Brindisi to Milan by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Milan, this guide helps you travel smarter and with confidence.

Most Brindisi to Milan buses use the Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) to Milano, Autostazione Lampugnano station pair, with some services arriving at Milano, San Donato - Settore B (Viale Giuseppe Impastato). Use this guide to compare Brindisi and Milan bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Milano, Autostazione Lampugnano is 5 km from Milan city centre. Public transport options include:
Milano, Autostazione Lampugnano has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Lampugnano (in the station), Trattoria Milano (0.5 km), Pizza Express (0.7 km).
Free Wi-Fi. ATMs are located near the main entrance.
Ticket office support is available at Milano, Autostazione Lampugnano.
Available at Milano, Autostazione Lampugnano: Parking, Taxis, WC.
Accessibility facilities are available at Milano, Autostazione Lampugnano: Elevators, ramps.
Milano, San Donato - Settore B (Viale Giuseppe Impastato) is 6 km from Milan city centre. Public transport options include:
Milano, San Donato - Settore B (Viale Giuseppe Impastato) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Italiana (in the station), Fast Food Express (in the station), Trattoria Milano (0.5 km).
Free Wi-Fi. ATMs are located near the main entrance for cash withdrawals.
Ticket office support is available at Milano, San Donato - Settore B (Viale Giuseppe Impastato).
Available at Milano, San Donato - Settore B (Viale Giuseppe Impastato): Parking, Taxis, WC.
Accessibility facilities are available at Milano, San Donato - Settore B (Viale Giuseppe Impastato): Elevators, ramps.
Here are some other resources that might have the information you need