The cheapest and fastest buses from Brindisi to Milan
Cheapest price
$60
Average price
$149
Fastest journey
12 h 40 m
Average duration
13 h 2 m
Buses per day
36
Distance
890 km
The best way to find a cheap bus ticket from Brindisi to Milan is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Brindisi to Milan will cost around $149 if you buy it on the day, but the cheapest tickets can be found for only $60.
Of the 36 buses that leave Brindisi for Milan on Sun, Dec 21, 8 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Dec 21 the direct buses cover the 890 km distance in an average of 13 h 2 m but if you time it right, some buses will get you there in just 12 h 40 m .
On Sun, Dec 21 the slowest buses will take 13 h 20 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
1110 · 2206
2204
2204
1120 · 2490
1120 · 2490
042
107 · 101
206 · 200
042
FlixBusBrindisi - MilanCompare Marino Autolinee, Itabus, FlixBus



Travel Information
Compare train, bus, and flight for Brindisi to Milan
Omio recommends booking the flight as it is the most popular option from Brindisi to Milan among Omio's users. If you are prioritising price take the bus with prices starting from €30. For those with little time consider booking a flight which can get you there in 1h 44m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.3 - 0.8kg. The ticket price range depends on the travel mode: a bus costs an average of €30, and a flight costs an average of €31.
Distance: 553 miles (890 km)
Compare bus with
| Bus | Most popular Flight | Train |
|---|---|---|
€67 Average price Cheapest | €152 Average price | €84 Average price |
13h 20m Average total duration 12h 50m Onboard + 30m Additional time* | 4h 44m Average total duration Fastest 1h 44m Onboard + 3h 0m Additional time* | 10h 39m Average total duration 10h 9m Onboard + 30m Additional time* |
0.9 - 2.2kg CO2 emissions | - CO2 emissions | 0.3 - 0.8kg CO2 emissions Lowest |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Brindisi to Milan Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Itabus | Departure Time 05:30AM | Arrival Time 12:35AM | Duration 19h05 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price $46 |
Operator Marino Autolinee | Departure Time 05:35AM | Arrival Time 07:25PM | Duration 13h50 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price $95 |
Operator FlixBus | Departure Time 06:15AM | Arrival Time 07:55PM | Duration 13h40 | Departure days Everyday | Cheapest price $64 |
Operator FlixBus | Departure Time 09:55AM | Arrival Time 04:00AM | Duration 18h05 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $64 |
Operator BlaBlaCar | Departure Time 10:00AM | Arrival Time 09:00PM | Duration 11h00 | Departure days Fri | Cheapest price $83 |
Operator FlixBus | Departure Time 10:35AM | Arrival Time 05:15AM | Duration 18h40 | Departure days Mon, Wed, Sat, Sun | Cheapest price $64 |
Operator Itabus | Departure Time 12:30PM | Arrival Time 07:35AM | Duration 19h05 | Departure days Mon, Tue, Wed, Thu, Sat, Sun | Cheapest price $45 |
Operator FlixBus | Departure Time 12:40PM | Arrival Time 07:20AM | Duration 18h40 | Departure days Mon, Tue, Wed, Sat, Sun | Cheapest price $55 |
Operator Itabus | Departure Time 03:25PM | Arrival Time 06:10AM | Duration 14h45 | Departure days Fri, Sun | Cheapest price $60 |
Operator BlaBlaCar | Departure Time 04:00PM | Arrival Time 01:20AM | Duration 9h20 | Departure days Fri | Cheapest price $107 |
Operator FlixBus | Departure Time 04:35PM | Arrival Time 08:50AM | Duration 16h15 | Departure days Wed | Cheapest price $55 |
Operator Marino Autolinee | Departure Time 05:45PM | Arrival Time 06:25AM | Duration 12h40 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $50 |
Operator Itabus | Departure Time 05:50PM | Arrival Time 07:30AM | Duration 13h40 | Departure days Everyday | Cheapest price $34 |
Operator FlixBus | Departure Time 05:55PM | Arrival Time 08:50AM | Duration 14h55 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price $64 |
Operator FlixBus | Departure Time 06:05PM | Arrival Time 07:25AM | Duration 13h20 | Departure days Mon, Fri, Sat, Sun | Cheapest price $106 |
Operator FlixBus | Departure Time 06:25PM | Arrival Time 08:50AM | Duration 14h25 | Departure days Wed, Thu, Fri, Sat, Sun | Cheapest price $54 |
Operator Marino Autolinee | Departure Time 08:50PM | Arrival Time 10:20AM | Duration 13h30 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price $102 |
Operator Itabus | Departure Time 09:05PM | Arrival Time 04:45PM | Duration 19h40 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $41 |
Operator FlixBus | Departure Time 09:30PM | Arrival Time 03:20PM | Duration 17h50 | Departure days Fri, Sat | Cheapest price $102 |
Operator Itabus | Departure Time 10:50PM | Arrival Time 04:45PM | Duration 17h55 | Departure days Everyday | Cheapest price $49 |
Operator FlixBus | Departure Time 11:30PM | Arrival Time 06:30PM | Duration 19h00 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $60 |
Live departures
Brindisi to Milan bus times
The table below shows live departures for Brindisi to Milan buses for today, Saturday, December 20. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
1120 · 2490 | 4:30 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 19h05 | 11:35 PM Milano, Autostazione Lampugnano | 1 transfer | |
1120 · 2490 | 4:30 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 18h19 | 10:49 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 1 transfer | |
206 · 200 | 4:35 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 13h50 | 6:25 PM Milano, Autostazione Lampugnano | 1 transfer | |
206 · 200 | 4:35 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 13h05 | 5:40 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 1 transfer | |
FlixBus | 5:15 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 13h40 | 6:55 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 0 transfersDirect | |
FlixBus | 5:15 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 14h30 | 7:45 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus · FlixBus | 8:55 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 18h05 | 3:00 AM Milano, Autostazione Lampugnano | 1 transfer | |
FlixBus · FlixBus | 9:35 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 18h40 | 4:15 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 1 transfer | |
1104 · 2422 | 11:30 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 19h05 | 6:35 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 1 transfer | |
1104 · 2494 | 11:30 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 18h25 | 5:55 AM Milano, Autostazione Lampugnano | 1 transfer | |
1104 · 3898 | 11:30 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 17h40 | 5:10 AM Milano, Autostazione Lampugnano | 1 transfer | |
FlixBus · FlixBus · FlixBus | 11:40 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 23h15 | 10:55 AM Milano, Milan Linate Airport | 2 transfers | |
FlixBus · FlixBus | 11:40 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 18h40 | 6:20 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 1 transfer | |
FlixBus · FlixBus | 11:40 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 17h25 | 5:05 AM Milano, Autostazione Lampugnano | 1 transfer | |
042 | 4:45 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 12h40 | 5:25 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 0 transfersDirect | |
042 | 4:45 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 13h15 | 6:00 AM Milano, Autostazione Lampugnano | 0 transfersDirect | |
2204 | 4:50 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 13h40 | 6:30 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 0 transfersDirect | |
2204 | 4:50 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 14h25 | 7:15 AM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus · FlixBus | 4:55 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 14h55 | 7:50 AM Milano, Autostazione Lampugnano | 1 transfer | |
FlixBus | 5:05 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 13h20 | 6:25 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 0 transfersDirect | |
FlixBus | 5:05 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 14h05 | 7:10 AM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus · FlixBus | 5:25 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 14h25 | 7:50 AM Milano, Autostazione Lampugnano | 1 transfer | |
107 · 101 | 7:50 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 13h30 | 9:20 AM Milano, Autostazione Lampugnano | 1 transfer | |
107 · 101 | 7:50 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 12h50 | 8:40 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 1 transfer | |
1226 · 3492 | 8:05 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 17h40 | 1:45 PM Milano, Autostazione Lampugnano | 1 transfer | |
1226 · 2126 | 8:05 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 18h55 | 3:00 PM Milano, Autostazione Lampugnano | 1 transfer | |
1226 · 3802 | 8:05 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 19h40 | 3:45 PM Milano, Autostazione Lampugnano | 1 transfer | |
FlixBus · FlixBus | 8:30 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 17h05 | 1:35 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 1 transfer | |
FlixBus · FlixBus | 8:30 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 17h50 | 2:20 PM Milano, Autostazione Lampugnano | 1 transfer | |
1108 · 3802 | 9:50 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 17h55 | 3:45 PM Milano, Autostazione Lampugnano | 1 transfer | |
1108 · 2126 | 9:50 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 17h10 | 3:00 PM Milano, Autostazione Lampugnano | 1 transfer | |
FlixBus · FlixBus | 10:30 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 17h40 | 4:10 PM Milano, Autostazione Lampugnano | 1 transfer | |
FlixBus · FlixBus | 10:30 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 19h00 | 5:30 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 1 transfer | |
FlixBus · FlixBus · FlixBus | 10:30 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 21h25 | 7:55 PM Milano, Milan Linate Airport | 2 transfers | |
| Sunday, December 21 | |||||
![]() | 3:30 AM Brindisi | 17h50 | 9:20 PM Milan | 0 transfersDirect | |
Find all the dates and times for this journey
Compare prices and tickets Brindisi to Milan by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Dec 20
Dec 21
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Dec 26
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Dec 28
Dec 29
Dec 30
Dec 31
Jan 01
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Jan 09
Journey information
Overview: Bus from Brindisi to Milan
Buses from Brindisi to Milan run on average 21 times per day, taking around 12h 50m. Cheap bus tickets for this journey start at $37 (€30) if you book in advance.
There are 5 buses per day. The earliest bus runs at 00:10, the last at 23:55. The fastest bus covers the 553 miles (890 km) distance in 12h 25m.
Distance 553 miles (890 km) |
Average bus duration 12h 50m |
Cheapest ticket price $37 (€30) |
Buses per day 21 |
Direct buses 5 |
Fastest bus 12h 25m |
First bus 00:10 |
Last bus 23:55 |
Bus providers: Marino Autolinee, Itabus, FlixBus, BlaBlaCar from Brindisi to MilanYou can travel by bus between Brindisi to Milan with Marino Autolinee, Itabus, FlixBus, BlaBlaCar for as low as $37 (€30). When you search for schedules and tickets, Omio will show you the best journey
Marino Autolinee
Itabus
FlixBus
BlaBlaCar
FAQs: Bus from Brindisi to Milan
Find answers to the most common questions about traveling from Brindisi to Milan by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Milan, this guide helps you travel smarter and with confidence.

Passengers board the bus most frequently from Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale), which is located around 0.6 miles (1 km) away from the city centre, and they get off the bus at Milano, Autostazione Lampugnano, located 4.7 miles (7.5 km) away from the city centre.
- Marino Autolinee
- Assistance
- Priority seating
- Accessible restrooms.
- Itabus
- Assistance
- Dedicated seating areas
- Accessible restrooms.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Duomo di Milano, an iconic Gothic cathedral known for its intricate facade and panoramic rooftop views
- Galleria Vittorio Emanuele II, a historic shopping arcade featuring luxury brands and elegant architecture
- Castello Sforzesco, a Renaissance fortress housing museums and art collections
- Santa Maria delle Grazie, a church famous for housing Leonardo da Vinci's The Last Supper
- Teatro alla Scala, a world-renowned opera house celebrated for its exceptional acoustics and performances.
- Visit the Duomo di Milano, an iconic Gothic cathedral with stunning architecture and panoramic rooftop views
- Explore The Last Supper, Leonardo da Vinci's renowned mural located in the Convent of Santa Maria delle Grazie
- Stroll through Galleria Vittorio Emanuele II, a historic shopping arcade with luxury boutiques and elegant cafes
- Discover Sforza Castle, a grand fortress housing several museums and art collections
- Relax in Sempione Park, a large green space perfect for leisurely walks and picnics near the city center.
- Marino Autolinee
- You can cancel your ticket up to 24 hours before departure for a full refund. Cancellations within 24 hours incur a 50% fee.
- Itabus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
To find the cheapest bus tickets for your trip from Brindisi to Milan, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- Marino Autolinee
- One carry-on bag up to 10kg (55x40x20 cm) and one checked bag up to 20kg (80x50x30 cm).
- Itabus
- One carry-on bag up to 10kg and one checked bag up to 20kg.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Marino Autolinee
- 10€ per additional bag up to 20 kg.
- Itabus
- 5€ per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
- Marino Autolinee
- Small pets allowed in carriers
- Larger pets must be leashed and muzzled.
- Itabus
- Small pets allowed in carriers
- Larger pets must be leashed and muzzled.
- FlixBus
- Small pets in carriers allowed
- Guide dogs travel for free.
popular bus stations
Popular bus stations from Brindisi to Milan
- 06:00-23:00
- Free Wi-Fi
- Cafeteria Lampugnano (in the station)
- Trattoria Milano (0.5 km)
- Pizza Express (0.7 km).
- Available outside the station.
- Elevators, ramps
- Available in the station.
- Metro: M1 Bus: 68, 78, 80
- 06:00-22:00
- Free Wi-Fi
- Cafeteria Italiana (in the station)
- Fast Food Express (in the station)
- Trattoria Milano (0.5 km).
- Available outside the station.
- Elevators, ramps
- Available in the station.
- Bus: 121, 132 Metro: M3
Most popular bus connections from Brindisi
More options for your journey from Brindisi to Milan
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