- Must visit
Royal Museums of Fine Arts of Belgium
Premier fine arts complex with Old Masters, Magritte, and modern collections, essential for understanding Belgian and European art.
2,000+ travel companies
2,000+ travel companies
Scan to get our free app
Use our app to get live travel updates and book mobile tickets for trains, buses, flights, and ferries.
App Store
4.942K ratings
Google Play
4.6136K reviews
The cheapest and fastest buses from Brindisi to Brussels
Showing times and prices for Aug 05
Cheapest price
€124
Average price
€159
Fastest journey
1 d 8 h 50 m
Average duration
1 d 12 h 52 m
Buses per day
6
Distance
1546 km
Cheap tickets
The best way to find a cheap bus ticket from Brindisi to Brussels is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Brindisi to Brussels will cost around €159 if you buy it on the day, but the cheapest tickets can be found for only €124.
Fast buses
It's difficult to get from Brindisi to Brussels without transferring at least 2 times.
FlixBus · FlixBus · FlixBus6:00 AM33h45Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)3:45 PMBrussels, Brussels South (Gare du Midi)€1241One-way2 transfers- FlixBus · FlixBus · FlixBus · FlixBus6:15 PM32h50Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)3:05 AMBrussels, Brussels South (Gare du Midi)€1461One-way3 transfers
- FlixBus · FlixBus · FlixBus · FlixBus6:00 AM40h10Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)10:10 PMBrussels, Avenue des Magnolias (King Baudouin)€1481One-way3 transfers
- FlixBus · FlixBus · FlixBus · FlixBus5:55 PM42h30Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)12:25 PMBrussels, Avenue des Magnolias (King Baudouin)€1581One-way3 transfers
- FlixBus · FlixBus · FlixBus · FlixBus11:30 PM40h20Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)3:50 PMBrussels, Gare Du Midi€1881One-way3 transfers
- FlixBus · FlixBus · FlixBus · FlixBus6:15 PM32h50Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)3:05 AMBrussels, Brussels South (Gare du Midi)€1461One-way3 transfers
- FlixBus · FlixBus · FlixBus6:00 AM33h45Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)3:45 PMBrussels, Brussels South (Gare du Midi)€1241One-way2 transfers
- FlixBus · FlixBus · FlixBus11:30 PM37h15Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)12:45 PMBrussels, Brussels South (Gare du Midi)€1901One-way2 transfers
- FlixBus · FlixBus · FlixBus · FlixBus6:00 AM40h10Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)10:10 PMBrussels, Avenue des Magnolias (King Baudouin)€1481One-way3 transfers
- FlixBus · FlixBus · FlixBus · FlixBus11:30 PM40h20Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)3:50 PMBrussels, Gare Du Midi€1881One-way3 transfers
Journey information
Overview: Bus from Brindisi to Brussels
Italy
Belgium
Buses from Brindisi to Brussels run on average 6 times per day, taking around 31h 45m. Cheap bus tickets for this journey start at €67 but you can travel from only €20 by flight.
The earliest bus runs at 00:45, the last at 23:30. The fastest bus covers the 960 miles (1546 km) distance in 32h 50m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from €20
Distance 960 miles (1546 km) |
Average bus duration 31h 45m |
Cheapest ticket price €67 |
Buses per day 6 |
Fastest bus 32h 50m |
First bus 12:45 AM |
Last bus 11:30 PM |
Cheapest Month Feb |
Cheapest Day Tue |
High Season Oct - Dec |
Low Season Apr - Jun |
Busiest Day Mon |
Least Busy Day Mon |
Best time to book 21 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from €20
Brindisi to Brussels Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 05:05AM | Arrival Time 04:55PM | Duration 35h50 | Departure days Thu, Fri, Sun | Cheapest price €71 |
Operator FlixBus | Departure Time 05:15AM | Arrival Time 04:55PM | Duration 35h40 | Departure days Thu, Fri, Sun | Cheapest price €67 |
Operator FlixBus | Departure Time 06:00AM | Arrival Time 03:45PM | Duration 33h45 | Departure days Mon, Tue, Wed, Sat | Cheapest price €122 |
Operator FlixBus | Departure Time 10:40AM | Arrival Time 01:05AM | Duration 38h25 | Departure days Thu | Cheapest price €155 |
Operator FlixBus | Departure Time 04:15PM | Arrival Time 05:20AM | Duration 37h05 | Departure days Fri | Cheapest price €124 |
Operator FlixBus | Departure Time 05:05PM | Arrival Time 09:00AM | Duration 39h55 | Departure days Thu | Cheapest price €154 |
Operator FlixBus | Departure Time 05:55PM | Arrival Time 12:25PM | Duration 42h30 | Departure days Mon, Tue, Wed, Sat | Cheapest price €158 |
Operator FlixBus | Departure Time 06:15PM | Arrival Time 03:05AM | Duration 32h50 | Departure days Mon, Tue, Wed, Sat | Cheapest price €137 |
Operator FlixBus | Departure Time 09:30PM | Arrival Time 01:35PM | Duration 40h05 | Departure days Fri, Sun | Cheapest price €121 |
Operator FlixBus | Departure Time 11:30PM | Arrival Time 03:50PM | Duration 40h20 | Departure days Mon, Tue, Wed, Sat | Cheapest price €160 |
Live departures
Brindisi to Brussels bus times
The table below shows live departures for Brindisi to Brussels buses for today, Tuesday, August 4. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| FlixBus · FlixBus · FlixBus | 6:00 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 35h55 | 5:55 PM Brussels, Brussels South (Gare du Midi) | 2 transfers | |
| FlixBus · FlixBus · FlixBus · FlixBus | 5:55 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 42h30 | 12:25 PM Brussels, Avenue des Magnolias (King Baudouin) | 3 transfers | |
| FlixBus · FlixBus · FlixBus · FlixBus | 6:15 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 32h50 | 3:05 AM Brussels, Brussels South (Gare du Midi) | 3 transfers | |
| FlixBus · FlixBus · FlixBus · FlixBus | 6:15 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 39h45 | 10:00 AM Brussels, Gare Du Midi | 3 transfers | |
| FlixBus · FlixBus · FlixBus | 11:30 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 37h15 | 12:45 PM Brussels, Brussels South (Gare du Midi) | 2 transfers | |
| FlixBus · FlixBus · FlixBus · FlixBus | 11:30 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 40h20 | 3:50 PM Brussels, Gare Du Midi | 3 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Why should you book Brindisi to Brussels buses with Omio?
FlixBus operates all buses services from Brindisi to Brussels.
Omio is an official ticket reseller for all your travel options from Brindisi to Brussels.
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Brindisi to Brussels.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Brindisi to Brussels.
Bus providers: FlixBus from Brindisi to BrusselsYou can travel by bus between Brindisi to Brussels with FlixBus for as low as €20. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
32h 50m
Cheapest Price
€67
FlixBus frequency
6 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Complete guide to Brussels
Things to do in Brussels
Discover the best of Brussels — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Brussels trip today.
- Must visit
Magritte Museum
Dedicated to surrealist René Magritte, this popular museum presents major works and context for one of Belgium’s most celebrated artists.
- Must visit
Comics Art Museum
Leading comic art museum in a Horta-designed building, highlighting Tintin, the Smurfs, and Belgium’s influential comics culture.
- Must visit
Grand Place
Grand square at Brussels’ heart, lined with ornate guildhalls and lively events, perfect for first-time visitors and evening atmosphere.
- Must visit
Parc du Cinquantenaire
Large urban park with the triumphal arch, museums, and wide lawns, excellent for walking, picnics, and classic city photographs.
- Must visit
Mont des Arts
Popular hilltop viewpoint and garden terrace with one of the best panoramas over central Brussels, especially at sunset.
Moules-Frites
Mussels steamed with white wine, celery and onion, often served with fries. A Brussels brasserie classic, especially popular in mussel season.
- Vegetarian
- Gluten-free
Frites
Double-fried potato fries, traditionally served in paper cones with sauces. They are a point of national pride and central to everyday Belgian street food.
Carbonnade Flamande
A rich beef and onion stew braised with Belgian dark beer. It is a beloved comfort dish found in traditional Brussels restaurants.
Bozar Restaurant
Two-Michelin-star restaurant by chef Karen Torosyan, celebrated for pâté en croûte and inventive fine dining in an intimate setting.
Brasserie La Paix
Elegant Belle Époque brasserie serving refined Belgian classics, seafood and game in a grand old-world dining room.
Maison Dandoy
Famous casual stop for Brussels waffles with many toppings. Popular, fast-moving and central for a classic sweet local treat.
Euro (€)
Moderate for Western Europe: hotels can be pricey, but dining and transit are manageable for most tourists.
Average meal costs
- Budget
- €8-15 for fast food or casual takeaway.
- Mid-range
- €20-35 per person for a standard restaurant meal.
- Fine dining
- €70+ per person for upscale restaurants.
- Coffee
- €3-5 for cappuccino or latte.
Tipping culture
Service is usually included. Round up or leave 5-10% for great restaurant service; round up taxi fares; small change is fine in cafes.
STIB-MIVB
Get the appOfficial public transport app
Prices
- Single ticket
- €2.50
- Day pass
- €8.40
To the city center
Brussels South (Gare du Midi) -> Brussels Central Station, Brussels
- Distance
- 2 km
- Travel time
- 5 min
- Contactless bank card payment is available on STIB-MIVB trams, buses, and metro gates. Buy the cheapest fare for occasional travel this way.
- Brussels South is also called Gare du Midi or Zuidstation. Validate paper tickets before boarding or at metro gates.
FAQs: Bus from Brindisi to Brussels
Find answers to the most common questions about traveling from Brindisi to Brussels by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Brindisi to Brussels can start from as little as €67 when you book in advance. The average bus ticket price for Brindisi to Brussels is €109 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Brindisi to Brussels is 32h 50m to travel the 960 miles (1546 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Brindisi to Brussels leaves at 12:45 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Brindisi to Brussels leaves at 11:30 PM.
There are 6 buses a day from Brindisi to Brussels which require at least one change with FlixBus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Brindisi to Brussels, you can count on FlixBus for the best way to get you to Brussels. You can also check all possible bus companies who offer a service between Brindisi and Brussels and compare the amenities they offer before buying a bus ticket.
When departing from Brindisi , you have various bus station options to start your journey from including Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) . When arriving in Brussels , you can end your journey in bus stations like Brussels, Brussels South (Gare du Midi), Brussels, Avenue des Magnolias (King Baudouin), Brussels, Gare Du Midi, Schaerbeek, Bd Roi Albert II (Bruxelles Gare Du Nord), Bruxelles, Gare du Nord .Passengers board the bus most frequently from Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale), which is located around away from the city centre, and they get off the bus at Brussels, Brussels South (Gare du Midi), located 2 away from the city centre.
It's helpful to compare your options as there are 3 ways to travel between Brindisi and Brussels including taking a train, bus, and flight.
Yes, the following accessibility options are available when taking the bus from Brindisi to Brussels:
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Brindisi to Brussels for bus company FlixBus.
Whether you can cancel your bus ticket from Brindisi to Brussels depends on the bus companies:
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Brindisi to Brussels.
Yes, the following luggage options are included when booking a bus ticket from Brindisi to Brussels:
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Brindisi to Brussels:
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Brindisi to Brussels. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from Brindisi to Brussels with the following bus company: FlixBus
Yes, there are USB plugs on board the bus from Brindisi to Brussels with the following bus company: FlixBus.
Yes, there is Wifi on board the bus from Brindisi to Brussels with the following bus company: FlixBus.
Belgium uses the euro (EUR) as its currency. Travelers generally find card payments widely accepted in cities, restaurants, and shops, though carrying some cash is advisable for small purchases or in rural areas.
In Brussels, travelers should be cautious of pickpocketing, especially in crowded areas like Grand Place, public transport, and popular tourist sites. Common scams include distraction techniques and fake petitions. It's advisable to stay vigilant, avoid displaying expensive items, and use official taxi services to ensure safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Brindisi to Brussels
Most Brindisi to Brussels buses use the Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) to Brussels, Brussels South (Gare du Midi) station pair, with some services arriving at Brussel, Avenue des Magnolias (Koning Boudewijn). Use this guide to compare Brindisi and Brussels bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Brindisi
Arrival bus stations in Brussels
Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)Brindisi Falcone Professional Institute, Via Giuseppe Maria Galanti 8, 72100
Which Brussels station do buses from Brindisi arrive at?
Buses from Brindisi to Brussels most often arrive at Brussels, Brussels South (Gare du Midi). Some services arrive at Brussel, Avenue des Magnolias (Koning Boudewijn), so check your ticket before travel to confirm your Brussels arrival station.
Brussels, Brussels South (Gare du Midi)Avenue Fonsny 47, 1060 Brussels, Belgium
City-centre transport
Getting to Brussels, Brussels South (Gare du Midi) from Brussels city centre
Brussels, Brussels South (Gare du Midi) is 2 km from Brussels city centre. Public transport options include:
TrainEuroCity · 4m · €1 · every ~2 min
Ice · 14m · €1
Bus48 · 16m · €3 · every ~9 min
Bus · 20m
FlixBus N1153 · 29m · €1
Subway2, 6 · 18m · €3 · every ~38 min
Brussels, Brussels South (Gare du Midi) bus station facilities and services
Brussels, Brussels South (Gare du Midi) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food and drink
Food options include: Cafeteria Midi (in the station), Belgian Bites (in the station), Fritland Express (0.5 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located near the main entrance and throughout the station.
Tickets and information
Ticket office support is available at Brussels, Brussels South (Gare du Midi).
Parking, taxis and toilets
Available at Brussels, Brussels South (Gare du Midi): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Brussels, Brussels South (Gare du Midi): Elevators, ramps.
Brussel, Avenue des Magnolias (Koning Boudewijn)
City-centre transport
Getting to Brussel, Avenue des Magnolias (Koning Boudewijn) from Brussels city centre
Bus811 · 22m · €1
N18 · 24m · €3
R40, R50, R41, R60 · 33m · €3 · every ~18 min
Tram93 · 40m · €3 · every ~14 min
Subway6 · 13m · €3 · every ~20 min
6 · 22m · €5 · every ~18 min
6 · 31m · €3 · every ~18 min
Brussels, Gare Du Midi
City-centre transport
Getting to Brussels, Gare Du Midi from Brussels city centre
TrainEuroCity · 4m · €1 · every ~2 min
Ice · 14m · €1
Bus48 · 16m · €3 · every ~9 min
Bus · 20m
FlixBus N1153 · 29m · €1
Subway2, 6 · 18m · €3 · every ~38 min
Most popular bus connections from Brindisi
More options for your journey from Brindisi to Brussels
Here are some other resources that might have the information you need
Most popular buses to and from Brussels and Brindisi
Most popular bus connections to Brussels
The Omio App Makes Travel Planning Easy
We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.
