- Must visit
Royal Museums of Fine Arts of Belgium
Premier fine arts complex with Old Masters, Magritte, and modern collections, essential for understanding Belgian and European art.
Cheapest price on Sep 19
$88
Average ticket price on Sep 19
$126
Fastest journey on Sep 19
1 d 11 h 40 m
Average journey duration on Sep 19
1 d 12 h 28 m
Buses on Sep 19
4
Distance
1546 km
The best way to find a cheap bus ticket from Brindisi to Brussels is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Brindisi to Brussels will cost around $126 if you buy it on the day, but the cheapest tickets can be found for only $88.
On Sat, Sep 19, we found 4 buses from Brindisi to Brussels, including 4 direct services.
On Sat, Sep 19 the direct buses cover the 1546 km distance in an average of 1 d 12 h 28 m but if you time it right, some buses will get you there in just 1 d 11 h 40 m .
On Sat, Sep 19 the slowest buses will take 1 d 13 h 15 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.








Omio recommends booking the flight as it is the most popular option from Brindisi to Brussels among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $223 For those with little time, consider booking a flight, which has an average total journey time of 5h 40m. Average ticket prices depend on the travel mode: a bus costs an average of $223, while a flight costs an average of $422.
Distance: 960 miles (1546 km)
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
$223 Average price Cheapest | $422 Average price | $545 Average price (fuel + tolls) | |
33h 28m Average total duration 32h 58m Onboard + 30m Additional time* | 5h 40m Average total duration Fastest 3h 40m Onboard + 2h 0m Additional time* | 19h 12m Average total duration (door-to-door) | |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Brindisi to Brussels:
A bus is $199 less than a flight for this route with tickets for a flight from Brindisi to Brussels costing on average $422.
Other travel options to Brussels take longer:
Bus takes on average 32h 58m.
Tickets start at around $223 compared to roughly $545 in fuel and tolls — a saving of about $322. The journey takes 32h 58m versus 19h 12m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 05:05AM | Arrival Time 04:55PM | Duration 35h50 | Departure days Sat | Cheapest price $128 |
Operator FlixBus | Departure Time 05:15AM | Arrival Time 04:55PM | Duration 35h40 | Departure days Sat | Cheapest price $88 |
Operator FlixBus | Departure Time 06:00AM | Arrival Time 05:55PM | Duration 35h55 | Departure days Mon, Wed, Thu, Fri, Sun | Cheapest price $113 |
Operator FlixBus | Departure Time 12:40PM | Arrival Time 03:05AM | Duration 38h25 | Departure days Thu | Cheapest price $108 |
Operator FlixBus | Departure Time 04:15PM | Arrival Time 05:20AM | Duration 37h05 | Departure days Sat | Cheapest price $155 |
Operator FlixBus | Departure Time 05:05PM | Arrival Time 06:20AM | Duration 37h15 | Departure days Sat | Cheapest price $132 |
Operator FlixBus | Departure Time 05:55PM | Arrival Time 12:25PM | Duration 42h30 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price $92 |
Operator FlixBus | Departure Time 06:15PM | Arrival Time 07:20AM | Duration 37h05 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price $95 |
Operator FlixBus | Departure Time 11:30PM | Arrival Time 12:45PM | Duration 37h15 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price $90 |
The table below shows live departures for Brindisi to Brussels buses for today, Friday, September 18. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus · FlixBus · FlixBus | 5:55 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 42h30 | 12:25 PM Brussels, Avenue des Magnolias (King Baudouin) | 3 transfers | |
FlixBus · FlixBus · FlixBus · FlixBus | 6:15 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 32h50 | 3:05 AM Brussels, Brussels South (Gare du Midi) | 3 transfers | |
FlixBus · FlixBus · FlixBus · FlixBus | 11:30 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 40h20 | 3:50 PM Brussels, Gare Du Midi | 3 transfers | |
FlixBus · FlixBus · FlixBus | 11:30 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 37h15 | 12:45 PM Brussels, Brussels South (Gare du Midi) | 2 transfers | |
| Saturday, September 19 | |||||
![]() | 5:05 AM Brindisi | 35h50 | 4:55 PM Brussels | 0 transfersDirect | |
![]() | 5:15 AM Brindisi | 35h40 | 4:55 PM Brussels | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Brindisi to Brussels run on average 6 times per day, taking around 32h 58m. Cheap bus tickets for this journey start at $102 but you can travel from only $21 by flight.
The earliest bus runs at 00:45, the last at 23:30. The fastest bus covers the 960 miles (1546 km) distance in 29h 15m.
Distance 960 miles (1546 km) |
Average bus duration 32h 58m |
Cheapest ticket price $102 |
Buses per day 6 |
Fastest bus 29h 15m |
First bus 12:45 AM |
Last bus 11:30 PM |
Cheapest Month Feb |
Cheapest Day Tue |
High Season Oct - Dec |
Low Season Apr - Jun |
Busiest Day Mon |
Least Busy Day Sat |
Best time to book 21 days |
Discover the best of Brussels — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Brussels trip today.
Premier fine arts complex with Old Masters, Magritte, and modern collections, essential for understanding Belgian and European art.
Dedicated to surrealist René Magritte, this popular museum presents major works and context for one of Belgium’s most celebrated artists.
Leading comic art museum in a Horta-designed building, highlighting Tintin, the Smurfs, and Belgium’s influential comics culture.
Grand square at Brussels’ heart, lined with ornate guildhalls and lively events, perfect for first-time visitors and evening atmosphere.
Large urban park with the triumphal arch, museums, and wide lawns, excellent for walking, picnics, and classic city photographs.
Popular hilltop viewpoint and garden terrace with one of the best panoramas over central Brussels, especially at sunset.
Mussels steamed with white wine, celery and onion, often served with fries. A Brussels brasserie classic, especially popular in mussel season.
Double-fried potato fries, traditionally served in paper cones with sauces. They are a point of national pride and central to everyday Belgian street food.
A rich beef and onion stew braised with Belgian dark beer. It is a beloved comfort dish found in traditional Brussels restaurants.
Two-Michelin-star restaurant by chef Karen Torosyan, celebrated for pâté en croûte and inventive fine dining in an intimate setting.
Elegant Belle Époque brasserie serving refined Belgian classics, seafood and game in a grand old-world dining room.
Famous casual stop for Brussels waffles with many toppings. Popular, fast-moving and central for a classic sweet local treat.
Moderate for Western Europe: hotels can be pricey, but dining and transit are manageable for most tourists.
Service is usually included. Round up or leave 5-10% for great restaurant service; round up taxi fares; small change is fine in cafes.
Official public transport app
Brussels South (Gare du Midi) -> Brussels Central Station, Brussels
Find answers to the most common questions about traveling from Brindisi to Brussels by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.

Most Brindisi to Brussels buses use the Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) to Brussels, Brussels South (Gare du Midi) station pair, with some services arriving at Brussel, Avenue des Magnolias (Koning Boudewijn). Use this guide to compare Brindisi and Brussels bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Brussels, Brussels South (Gare du Midi) is 2 km from Brussels city centre. Public transport options include:
Brussels, Brussels South (Gare du Midi) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Midi (in the station), Belgian Bites (in the station), Fritland Express (0.5 km).
Free Wi-Fi. ATMs are located near the main entrance and throughout the station.
Ticket office support is available at Brussels, Brussels South (Gare du Midi).
Available at Brussels, Brussels South (Gare du Midi): Parking, Taxis, WC.
Accessibility facilities are available at Brussels, Brussels South (Gare du Midi): Elevators, ramps.
Brussel, Avenue des Magnolias (Koning Boudewijn) is 5 km from Brussels city centre. Public transport options include:
Brussel, Avenue des Magnolias (Koning Boudewijn) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Brussel, Avenue des Magnolias (Koning Boudewijn). ATMs are available at Brussel, Avenue des Magnolias (Koning Boudewijn).
Ticket office support is available at Brussel, Avenue des Magnolias (Koning Boudewijn).
Available at Brussel, Avenue des Magnolias (Koning Boudewijn): Parking, Taxis, WC.
Accessibility facilities are available at Brussel, Avenue des Magnolias (Koning Boudewijn): Accessible for people with reduced mobility.
Brussels, Gare Du Midi is 1 km from Brussels city centre. Public transport options include:
Brussels, Gare Du Midi has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Various dining options are nearby.
Wi-Fi is available at Brussels, Gare Du Midi. ATMs are available at Brussels, Gare Du Midi.
Ticket office support is available at Brussels, Gare Du Midi.
Available at Brussels, Gare Du Midi: Parking, Taxis, WC.
Accessibility facilities are available at Brussels, Gare Du Midi: Station is accessible for individuals with disabilities.
Here are some other resources that might have the information you need