Travel Information
Compare train and bus for Karlsruhe to Lyon
Omio recommends booking the train as it is the most popular option from Karlsruhe to Lyon among Omio's users. If you are prioritising price take the bus with prices starting from $26. For those with little time consider booking a train which can get you there in 4h 43m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of $26, and a train costs an average of $64.
Distance: 278 miles (449 km)
Compare train with
Most popular Train | Bus |
|---|---|
$138 Average price | $43 Average price Cheapest |
5h 13m Average total duration Fastest 4h 43m Onboard + 30m Additional time* | 8h 8m Average total duration 7h 38m Onboard + 30m Additional time* |
0.1 - 0.4kg CO2 emissions Lowest | 0.4 - 1.1kg CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom Karlsruhe to Lyon
How to get from Karlsruhe to Lyon by train, bus or flight.
Our recommendation
The best way to travel from Karlsruhe to Lyon is by taking a bus because it’s the best combination of price and speed.
FlixBusCheapest
51510Fastest
9580Other options
ICE 9568+
9877
ICE 9568+
5537
ICE 9568+
12177
FlixBus
FlixBus
ICE 376 · ICE 614+
LH1076
ICE 204+
LH1076
ICE 202+
LH1078Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Karlsruhe to Lyon
Travel to Lyon easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Karlsruhe to Lyon.

This is compared to other travel options from Karlsruhe to Lyon:
A bus is $38 (€30) less than a train for this route with tickets for a train from Karlsruhe to Lyon costing on average $64 (€51).
Other travel options to Lyon take longer:
Bus takes on average 7h 55m.
- Around 7 buses per day.
- Around 6 trains per day.
However, we recommend checking specific travel dates for your route between Karlsruhe and Lyon as scheduled services by train and bus can vary by season or day of the week.
- Trains mostly depart from Karlsruhe Hbf and arrive in Lyon Part Dieu.
- Buses mostly depart from Karlsruhe Hbf and arrive in Lyon, Perrache Bus Station.
- Travel with FlixBus, BlaBlaCar Bus, BlaBlaCar to go to Lyon by bus.
- Travel with TGV, TGV INOUI, SNCF TER, Deutsche Bahn to go to Lyon by train.
- 6 direct buses per day with FlixBus, BlaBlaCar Bus, BlaBlaCar.
- 1 direct trains per day with Deutsche Bahn.
Travelling from Karlsruhe to Lyon: related information
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