Travel Information
Compare train and bus for Karlsruhe to Lyon
Omio recommends booking the train as it is the most popular option from Karlsruhe to Lyon among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $39 For those with little time, consider booking a train, which has an average total journey time of 5h 32m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.1 - 0.4kg. Average ticket prices depend on the travel mode: a bus costs an average of $39, while a train costs an average of $129.
Distance: 278 miles (449 km)
Compare train with
Most popular Train | Bus | Driving |
|---|---|---|
$129 Average price | $39 Average price Cheapest | $152 Average price (fuel + tolls) |
5h 32m Average total duration Fastest 5h 2m Onboard + 30m Additional time* | 8h 38m Average total duration 8h 8m Onboard + 30m Additional time* | 5h 54m Average total duration (door-to-door) |
0.1 - 0.4kg CO2 emissions Lowest | 0.4 - 1.1kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Karlsruhe to Lyon:
A bus is $89 (€72) less than a train for this route with tickets for a train from Karlsruhe to Lyon costing on average $129 (€104).
Other travel options to Lyon take longer:
Bus takes on average 8h 38m.
The journey is about 52m faster (5h 2m by train vs 5h 54m by car) and roughly $24 (€19) cheaper once you factor in fuel and tolls ($129 (€104) vs $152 (€124)). You'll also arrive in the city centre rather than hunting for parking, and you can work, read, or watch the landscape go by instead of concentrating on the road.
Driving is still worth considering if you want to stop along the way or need a car once you arrive.
Travel optionsfrom Karlsruhe to Lyon
How to get from Karlsruhe to Lyon by train, bus or flight.
Our recommendation
The best way to travel from Karlsruhe to Lyon is by taking a bus because it’s the best combination of price and speed.
FlixBus11:55 PM8h20Karlsruhe Hbf8:15 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$381One-way0 transfers
Cheapest
FlixBus11:55 PM8h20Karlsruhe Hbf8:15 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$381One-way0 transfers
Fastest
95803:12 PM4h46Karlsruhe Hbf7:58 PMLyon Part Dieu$1131One-way0 transfers
Other options
5537+
959012:08 PM5h51Karlsruhe Hbf5:59 PMLyon Part Dieu$1051One-way1 transfer
9877+
95688:06 AM4h53Karlsruhe Hbf12:59 PMLyon Part Dieu$1501One-way1 transfer
9572+
66333:32 PM7h38Karlsruhe Hbf11:10 PMLyon Part Dieu$1641One-way1 transfer
FlixBus4:05 AM8h45Karlsruhe Hbf12:50 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$381One-way0 transfers
FlixBus3:20 PM7h55Karlsruhe Hbf11:15 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$391One-way0 transfers
FlixBus10:25 AM10h25Karlsruhe Hbf8:50 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$441One-way0 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Sep 03
Sep 04
Sep 05
Sep 06
Sep 07
Sep 08
Sep 09
Sep 10
Sep 11
Sep 12
Sep 13
Sep 14
Sep 15
Sep 16
More than 1,000 travel companies trust us to sell their tickets all in one place.
FAQs: Travel from Karlsruhe to Lyon
Travel to Lyon easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Karlsruhe to Lyon.

This is compared to other travel options from Karlsruhe to Lyon:
A bus is $89 (€72) less than a train for this route with tickets for a train from Karlsruhe to Lyon costing on average $129 (€104).
Other travel options to Lyon take longer:
Bus takes on average 8h 38m.
- Around 7 buses per day.
- Around 6 trains per day.
However, we recommend checking specific travel dates for your route between Karlsruhe and Lyon as scheduled services by train and bus can vary by season or day of the week.
- Trains mostly depart from Karlsruhe Hbf and arrive in Lyon Part Dieu.
- Buses mostly depart from Karlsruhe Hbf and arrive in Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland).
- Travel with FlixBus, BlaBlaCar Bus, BlaBlaCar, Alsa to go to Lyon by bus.
- Travel with TGV, SNCF | TGV INOUI, SNCF | Intercités, SNCF TER | Operated by SNCF Voyageurs 1187, Deutsche Bahn Intercity (DB IC) to go to Lyon by train.
- 6 direct buses per day with FlixBus, BlaBlaCar Bus, BlaBlaCar, Alsa.
- 1 direct trains per day with SNCF | TGV INOUI.
Travelling from Karlsruhe to Lyon: related information
Here are some other resources that might have the information you need
