Travel Information
Compare train and bus for Karlsruhe to Lyon
Omio recommends booking the train as it is the most popular option from Karlsruhe to Lyon among Omio's users. If you are prioritising price take the bus with prices starting from $25. For those with little time consider booking a train which can get you there in 5h 2m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of $25, and a train costs an average of $73.
Distance: 278 miles (449 km)
Compare train with
Most popular Train | Bus | Driving |
|---|---|---|
$139 Average price | $38 Average price Cheapest | $152 Average price (fuel + tolls) |
5h 32m Average total duration Fastest 5h 2m Onboard + 30m Additional time* | 8h 8m Average total duration 7h 38m Onboard + 30m Additional time* | 5h 54m Average total duration (door-to-door) |
0.1 - 0.4kg CO2 emissions Lowest | 0.4 - 1.1kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Karlsruhe to Lyon:
A bus is $100 (€81) less than a train for this route with tickets for a train from Karlsruhe to Lyon costing on average $139 (€112).
Other travel options to Lyon take longer:
Bus takes on average 7h 38m.
Travel optionsfrom Karlsruhe to Lyon
How to get from Karlsruhe to Lyon by train, bus or flight.
Our recommendation
The best way to travel from Karlsruhe to Lyon is by taking a bus because it’s the best combination of price and speed.
FlixBus3:20 PM7h55Karlsruhe Hbf11:15 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$531One-way0 transfers
Cheapest
FlixBus3:20 PM7h55Karlsruhe Hbf11:15 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$531One-way0 transfers
Fastest
9576 · 66179:53 AM6h03Karlsruhe Hbf3:56 PMLyon Part Dieu$5221One-way1 transfer
Other options
4709+
12177+
874086:07 AM11h52Karlsruhe Hbf5:59 PMLyon Part Dieu$1341One-way2 transfers
4709+
5537+
874086:07 AM11h52Karlsruhe Hbf5:59 PMLyon Part Dieu$1341One-way2 transfers
ICE 277+
12177+
8742410:06 AM7h53Karlsruhe Hbf5:59 PMLyon Part Dieu$1441One-way2 transfers
FlixBus4:05 AM8h45Karlsruhe Hbf12:50 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$531One-way0 transfers
FlixBus11:55 PM8h20Karlsruhe Hbf8:15 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$541One-way0 transfers
515109:05 PM8h05Karlsruhe, Hinterm Hauptbahnhof (Südeingang)5:10 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$741One-way0 transfers
TGV 9561+
ICE 126+
AF7370+
AF12199:54 AM11h31Karlsruhe Hbf9:25 PMLyon Saint Exupery Airport$3051One-way3 transfers
ICE 204+
AF7370+
AF16196:59 AM14h26Karlsruhe Hbf9:25 PMLyon Saint Exupery Airport$3201One-way2 transfers
ICE 202+
AF7370+
AF12198:59 AM12h26Karlsruhe Hbf9:25 PMLyon Saint Exupery Airport$3281One-way2 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Karlsruhe to Lyon
Travel to Lyon easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Karlsruhe to Lyon.

This is compared to other travel options from Karlsruhe to Lyon:
A bus is $100 (€81) less than a train for this route with tickets for a train from Karlsruhe to Lyon costing on average $139 (€112).
Other travel options to Lyon take longer:
Bus takes on average 7h 38m.
- Around 7 buses per day.
- Around 6 trains per day.
However, we recommend checking specific travel dates for your route between Karlsruhe and Lyon as scheduled services by train and bus can vary by season or day of the week.
- Trains mostly depart from Karlsruhe Hbf and arrive in Lyon Part Dieu.
- Buses mostly depart from Karlsruhe Hbf and arrive in Lyon, Perrache Bus Station.
- Travel with TGV, SNCF | TGV INOUI, SNCF | Intercités, SNCF TER | Operated by SNCF Voyageurs 1187, Deutsche Bahn Intercity (DB IC) to go to Lyon by train.
- Travel with FlixBus, BlaBlaCar Bus, BlaBlaCar to go to Lyon by bus.
- 1 direct trains per day with TGV, SNCF | TGV INOUI.
- 6 direct buses per day with FlixBus, BlaBlaCar Bus, BlaBlaCar.
Travelling from Karlsruhe to Lyon: related information
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