Travel Information
Compare train and bus for Lyon to Karlsruhe
Omio recommends booking the train as it is the most popular option from Lyon to Karlsruhe among Omio's users. If you are prioritising price take the bus with prices starting from $25. For those with little time consider booking a train which can get you there in 5h 2m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of $25, and a train costs an average of $64.
Distance: 278 miles (449 km)
Compare train with
Most popular Train | Bus | Driving |
|---|---|---|
$130 Average price | $37 Average price Cheapest | $152 Average price (fuel + tolls) |
5h 32m Average total duration Fastest 5h 2m Onboard + 30m Additional time* | 8h 29m Average total duration 7h 59m Onboard + 30m Additional time* | 5h 53m Average total duration (door-to-door) |
0.1 - 0.4kg CO2 emissions Lowest | 0.4 - 1.1kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Lyon to Karlsruhe:
A bus is $93 (€75) less than a train for this route with tickets for a train from Lyon to Karlsruhe costing on average $130 (€106).
Other travel options to Karlsruhe take longer:
Bus takes on average 7h 59m.
Travel optionsfrom Lyon to Karlsruhe
How to get from Lyon to Karlsruhe by train, bus or flight.
Our recommendation
The best way to travel from Lyon to Karlsruhe is by taking a bus because it’s the best combination of price and speed.
515113:20 AM8h15Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)11:35 AMKarlsruhe, Hinterm Hauptbahnhof (Südeingang)$251One-way0 transfers
Cheapest
515113:20 AM8h15Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)11:35 AMKarlsruhe, Hinterm Hauptbahnhof (Südeingang)$251One-way0 transfers
Fastest
LH1083+
ICE 1036:55 AM4h04Lyon Saint Exupery Airport10:59 AMKarlsruhe Hbf$3291One-way1 transfer
Other options
TGV 958310:01 AM4h49Lyon Part Dieu2:50 PMKarlsruhe Hbf$921One-way0 transfers
12176+
956311:38 AM6h14Lyon Part Dieu5:52 PMKarlsruhe Hbf$1171One-way1 transfer
9898+
95738:32 AM4h52Lyon Part Dieu1:24 PMKarlsruhe Hbf$1471One-way1 transfer
FlixBus5:05 PM8h45Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)1:50 AMKarlsruhe Hbf$321One-way0 transfers
FlixBus10:00 PM8h20Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)6:20 AMKarlsruhe Hbf$331One-way0 transfers
FlixBus5:20 AM7h55Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)1:15 PMKarlsruhe Hbf$341One-way0 transfers
EN8911+
ICE 20310:30 AM10h29Lyon Saint Exupery Airport8:59 PMKarlsruhe Hbf$2701One-way1 transfer
KL1426+
ICE 203+
KL18196:30 AM14h29Lyon Saint Exupery Airport8:59 PMKarlsruhe Hbf$2731One-way2 transfers
EN8911+
ICE 10710:30 AM4h29Lyon Saint Exupery Airport2:59 PMKarlsruhe Hbf$2741One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
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FAQs: Travel from Lyon to Karlsruhe
Travel to Karlsruhe easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Lyon to Karlsruhe.

This is compared to other travel options from Lyon to Karlsruhe:
A bus is $93 (€75) less than a train for this route with tickets for a train from Lyon to Karlsruhe costing on average $130 (€106).
Other travel options to Karlsruhe take longer:
Bus takes on average 7h 59m.
- Around 8 buses per day.
- Around 7 trains per day.
However, we recommend checking specific travel dates for your route between Lyon and Karlsruhe as scheduled services by train and bus can vary by season or day of the week.
- Trains mostly depart from Lyon Part Dieu and arrive in Karlsruhe Hbf.
- Buses mostly depart from Lyon, Perrache Bus Station and arrive in Karlsruhe Hbf.
- Travel with FlixBus, BlaBlaCar Bus, BlaBlaCar, Alsa to go to Karlsruhe by bus.
- Travel with TGV, SNCF | TGV INOUI, SNCF | Intercités to go to Karlsruhe by train.
- 6 direct buses per day with FlixBus, BlaBlaCar Bus, BlaBlaCar, Alsa.
- 2 direct trains per day with TGV, SNCF | TGV INOUI.
Travelling from Lyon to Karlsruhe: related information
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