Travel Information
Compare train and bus for Lyon to Karlsruhe
Omio recommends booking the train as it is the most popular option from Lyon to Karlsruhe among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $53 For those with little time, consider booking a train, which has an average total journey time of 5h 7m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.1 - 0.4kg. Average ticket prices depend on the travel mode: a bus costs an average of $53, while a train costs an average of $94.
Distance: 278 miles (449 km)
Compare train with
Most popular Train | Bus | Driving |
|---|---|---|
$94 Average price | $53 Average price Cheapest | $149 Average price (fuel + tolls) |
5h 7m Average total duration Fastest 4h 37m Onboard + 30m Additional time* | 9h 24m Average total duration 8h 54m Onboard + 30m Additional time* | 5h 53m Average total duration (door-to-door) |
0.1 - 0.4kg CO2 emissions Lowest | 0.4 - 1.1kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Compare ways to travel from Lyon to Karlsruhe
Compare the available ways to get from Lyon to Karlsruhe, with the key details around price, speed, convenience, and direct service.
This is compared to other travel options from Lyon to Karlsruhe:
A bus is $42 (€35) less than a train for this route with tickets for a train from Lyon to Karlsruhe costing on average $94 (€79).
Other travel options to Karlsruhe take longer:
Bus takes on average 9h 24m.
The journey is about 1h 16m faster (4h 37m by train vs 5h 53m by car) and roughly $56 (€47) cheaper once you factor in fuel and tolls ($94 (€79) vs $149 (€125)). You'll also arrive in the city centre rather than hunting for parking, and you can work, read, or watch the landscape go by instead of concentrating on the road.
Driving is still worth considering if you want to stop along the way or need a car once you arrive.
Travel optionsfrom Lyon to Karlsruhe
How to get from Lyon to Karlsruhe by train, bus or flight.
Our recommendation
The best way to travel from Lyon to Karlsruhe is by taking a bus because it’s the best combination of price and speed.
FlixBus5:20 AM7h55Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)1:15 PMKarlsruhe Hbf$531One-way0 transfers
Cheapest
FlixBus5:20 AM7h55Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)1:15 PMKarlsruhe Hbf$531One-way0 transfers
Fastest
LH1083+
ICE 1037:05 AM3h54Lyon Saint Exupery Airport10:59 AMKarlsruhe Hbf$4771One-way1 transfer
Other options
STR 3+
TGV 958310:01 AM5h12Lyon Part Dieu3:13 PMEuropaplatz/Post Galerie (Karlstraße)$1461One-way1 transfer
12176+
956311:38 AM6h14Lyon Part Dieu5:52 PMKarlsruhe Hbf$1581One-way1 transfer
12176 · 957711:38 AM6h47Lyon Part Dieu6:25 PMKarlsruhe Hbf$1651One-way1 transfer
FlixBus3:10 AM7h55Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)11:05 AMKarlsruhe Hbf$611One-way0 transfers
FlixBus5:05 PM8h45Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)1:50 AMKarlsruhe Hbf$641One-way0 transfers
FlixBus11:00 PM9h10Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)8:10 AMKarlsruhe Hbf$641One-way0 transfers
KL1426 · KL1817+
ICE 1076:30 AM8h29Lyon Saint Exupery Airport2:59 PMKarlsruhe Hbf$3881One-way2 transfers
KL1426 · KL1819+
ICE 1096:30 AM10h29Lyon Saint Exupery Airport4:59 PMKarlsruhe Hbf$3881One-way2 transfers
KL1426 · KL1817+
ICE 1096:30 AM10h29Lyon Saint Exupery Airport4:59 PMKarlsruhe Hbf$3881One-way2 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Lyon to Karlsruhe
Travel to Karlsruhe easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Lyon to Karlsruhe.

This is compared to other travel options from Lyon to Karlsruhe:
A bus is $42 (€35) less than a train for this route with tickets for a train from Lyon to Karlsruhe costing on average $94 (€79).
Other travel options to Karlsruhe take longer:
Bus takes on average 9h 24m.
- Around 13 trains per day.
- Around 7 buses per day.
However, we recommend checking specific travel dates for your route between Lyon and Karlsruhe as scheduled services by train and bus can vary by season or day of the week.
- Trains mostly depart from Lyon Part Dieu and arrive in Karlsruhe Hbf.
- Buses mostly depart from Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) and arrive in Karlsruhe Hbf.
- Travel with FlixBus, BlaBlaCar Bus, Alsa to go to Karlsruhe by bus.
- Travel with TGV, SNCF | TGV INOUI, SNCF | Intercités de nuit to go to Karlsruhe by train.
- 6 direct buses per day with FlixBus, BlaBlaCar Bus, Alsa.
- 2 direct trains per day with TGV, SNCF | TGV INOUI.
Travelling from Lyon to Karlsruhe: related information
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