The cheapest and fastest trains from Karlsruhe to Mainz
Cheapest price
$35
Average price
$55
Fastest journey
1 h 41 m
Average duration
1 h 45 m
Trains per day
16
Distance
109 km
The best way to find a cheap train ticket from Karlsruhe to Mainz is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Karlsruhe to Mainz will cost around $55 if you buy it on the day, but the cheapest tickets can be found for only $35.
Of the 16 trains that leave Karlsruhe for Mainz on Sat, Mar 28, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Mar 28 the direct trains cover the 109 km distance in an average of 1 h 45 m but if you time it right, some trains will get you there in just 1 h 41 m .
On Sat, Mar 28 the slowest trains will take 1 h 48 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
ICE 378 · S605:59AM2h09Karlsruhe Hbf08:08AMMainz Hbf$351One-way1 transfer
S9 · S507:12AM2h26Karlsruhe Hbf09:38AMMainz Hbf$391One-way1 transfer
S11+
S9 · S507:03AM2h29Karlsruhe Albtalbf09:32AMMainz Römisches Theater station$531One-way2 transfers
E+
S9 · S509:05AM2h27Karlsruhe Albtalbf11:32AMMainz Römisches Theater station$531One-way2 transfers
S9 · S507:12AM2h26Karlsruhe Hbf09:38AMMainz Hbf$531One-way1 transfer
448408:06AM1h41Karlsruhe Hbf09:47AMMainz Hbf$531One-way0 transfers
ICE 204 · 475206:59AM1h44Karlsruhe Hbf08:43AMMainz Hbf$561One-way1 transfer
204+
475206:59AM1h44Karlsruhe Hbf08:43AMMainz Hbf$561One-way1 transfer
202+
475608:59AM1h47Karlsruhe Hbf10:46AMMainz Hbf$561One-way1 transfer
8 · 1012 · S808:37AM1h48Karlsruhe Hbf10:25AMMainz Hbf$661One-way2 transfers
Travel Information
Compare train and bus for Karlsruhe to Mainz
Omio recommends booking the train as it is the most popular option from Karlsruhe to Mainz among Omio's users. If you are prioritising price take the bus with prices starting from $8. For those with little time consider booking a train which can get you there in 1h 20m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.0 - 0.1kg. The ticket price range depends on the travel mode: a bus costs an average of $8, and a train costs an average of $13.
Distance: 67 miles (109 km)
Compare train with
Most popular Train | Bus |
|---|---|
$31 Average price | $17 Average price Cheapest |
1h 50m Average total duration Fastest 1h 20m Onboard + 30m Additional time* | 2h 35m Average total duration 2h 5m Onboard + 30m Additional time* |
0.0 - 0.1kg CO2 emissions Lowest | 0.1 - 0.3kg CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Karlsruhe to Mainz train times
The table below shows live departures for Karlsruhe to Mainz trains for today, Friday, March 27. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
IC 60402 · ICE 698 · S8 | Delayed 12:24 AM 12:24 AMKarlsruhe Hbf | 4h01 | 4:25 AM Mainz Hbf | 2 transfers | |
| Saturday, March 28 | |||||
ICE 378 · ICE 616 · 29508 | On time 4:59 AM Karlsruhe Hbf | 1h50 | 6:49 AM Mainz Hbf | 2 transfers | |
ICE 378 · S6 | On time 4:59 AM Karlsruhe Hbf | 2h09 | 7:08 AM Mainz Hbf | 1 transfer | |
76+ 1014 · S8 | 5:37 AM Karlsruhe Hbf | 1h52 | 7:29 AM Mainz Hbf | 2 transfers | |
ECE 76 · ICE 1014 · S8 | On time 5:37 AM Karlsruhe Hbf | 1h52 | 7:29 AM Mainz Hbf | 2 transfers | |
ICE 204 · 4752 | On time 5:59 AM Karlsruhe Hbf | 1h44 | 7:43 AM Mainz Hbf | 1 transfer | |
204+ 4752 | 5:59 AM Karlsruhe Hbf | 1h44 | 7:43 AM Mainz Hbf | 1 transfer | |
S11+ S9 · S5 | 6:03 AM Karlsruhe Albtalbf | 2h29 | 8:32 AM Mainz Römisches Theater station | 2 transfers | |
S9 · S5 | 6:12 AM Karlsruhe Hbf | 2h26 | 8:38 AM Mainz Hbf | 1 transfer | |
S9 · S5 | 6:12 AM Karlsruhe Hbf | 2h26 | 8:38 AM Mainz Hbf | 1 transfer | |
S51+ 4484 · S6 | 6:56 AM Karlsruhe Albtalbf | 2h06 | 9:02 AM Mainz Römisches Theater station | 2 transfers | |
4484 | 7:06 AM Karlsruhe Hbf | 1h41 | 8:47 AM Mainz Hbf | 0 transfersDirect | |
8+ S5 | 7:37 AM Karlsruhe Hbf | 1h59 | 9:36 AM Mainz Hbf | 1 transfer | |
8 · 1012 · S8 | 7:37 AM Karlsruhe Hbf | 1h48 | 9:25 AM Mainz Hbf | 2 transfers | |
202+ 4756 | 7:59 AM Karlsruhe Hbf | 1h47 | 9:46 AM Mainz Hbf | 1 transfer | |
E+ S9 · S5 | 8:05 AM Karlsruhe Albtalbf | 2h27 | 10:32 AM Mainz Römisches Theater station | 2 transfers | |
S9 · S5 | 8:12 AM Karlsruhe Hbf | 2h26 | 10:38 AM Mainz Hbf | 1 transfer | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Karlsruhe to Mainz by train or bus
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 28
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Apr 01
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Apr 03
Why should you book Karlsruhe to Mainz trains with Omio?
Why book with Omio vs Deutsche Bahn?
- Compare with other providers: On Omio, you can not only buy tickets for Deutsche Bahn, but also compare tickets for the likes of Süwex or ÖBB | Nightjet to find the best option for your trip from Karlsruhe to Mainz.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Deutsche Bahn with all available travel options, which are train and bus to ensure you get the best deal for traveling from Karlsruhe to Mainz.
Why book with Omio over Trainline or Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including train and bus to find the ideal travel option from Karlsruhe to Mainz.
Journey information
Overview: Train from Karlsruhe to Mainz
Trains from Karlsruhe to Mainz run on average 9 times per day, taking around 1h 20m. Cheap train tickets for this journey start at $13 (€11) but you can travel from only $8 (€6) by bus.
There are 2 trains per day. The earliest train runs at 00:02, the last at 23:49. The fastest train covers the 67 miles (109 km) distance in 1h 14m.
Distance 67 miles (109 km) |
Average train duration 1h 20m |
Cheapest ticket price $13 (€11) |
Trains per day 9 |
Direct trains 2 |
Fastest train 1h 14m |
First train 00:02 |
Last train 23:49 |
Train companies: Deutsche Bahn, Süwex, ÖBB | Nightjet from Karlsruhe to Mainz trainsDeutsche Bahn, Süwex, ÖBB | Nightjet trains will get you between Karlsruhe and Mainz from $8 (€6). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Deutsche Bahn
A Bordrestaurant (restaurant car) where you can sit and eat.
A Bordbistro (bistro bar) with snacks, hot meals, and drinks to-go.
At-seat service in 1st class: staff will take your order and serve food/drinks directly to your seat.
Regional trains (RE / RB / S-Bahn):
No onboard catering.
You’re welcome to bring your own food and drinks.
Not included by default.
You can add a seat reservation when booking (recommended for busy routes).
Costs around €4.90 per seat (or €5.90 if booked separately later).
First Class:
Yes, always included in the ticket price.
Allowed for free if they can fit in a transport box (max. size: hand luggage).
Must stay in the box for the entire journey.
Large dogs:
Require a separate (paid) ticket — typically half the price of a regular second-class ticket.
Must be leashed and wear a muzzle while on the train.
Cannot sit on seats.
Assistance dogs:
Travel free of charge.
Do not need a muzzle or leash if medically not required.
Allowed to accompany the passenger at all times.
ÖBB | Nightjet
Süwex
FAQs: Trains from Karlsruhe to Mainz
Find answers to the most common questions about traveling from Karlsruhe to Mainz by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Mainz, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Karlsruhe to Mainz
- Monday: 06:30 - 21:00
- Tuesday: 06:30 - 21:00
- Wednesday: 06:30 - 21:00
- Thursday: 06:30 - 21:00
- Friday: 06:30 - 21:00
- Saturday: 08:00 - 19:00
- Sunday: 09:00 - 20:00
- Vinarte
- Am Tiergarten
- Panorama
- Alter Brauhof
- Hotel Barbarossa
- Hotel Avisa
- Am Tiergarten
- Aparthotel Aijana
- Monday: 08:00 13:30 - 12:30 18:00
- Tuesday: 08:00 13:30 - 12:30 18:00
- Wednesday: 08:00 13:30 - 12:30 18:00
- Thursday: 08:00 13:30 - 12:30 18:00
- Friday: 08:00 13:30 - 12:30 18:00
- Saturday: 09:00 - 13:00
- Hubraum
- Vogel Hausbräu Durlach
- Asia Gourmet
- Borsalino
- Hotel Große Linde
- Zum Erwin
- Der Blaue Reiter
- Adler
- Denkfabrik
- Cafeteria
- Asia Imbiss
- Auerhahn
- Monday: 06:00 - 21:15
- Tuesday: 06:00 - 21:15
- Wednesday: 06:00 - 21:15
- Thursday: 06:00 - 21:15
- Friday: 06:00 - 21:15
- Saturday: 07:00 - 19:00
- Sunday: 08:00 - 20:00
- Mangal
- Asia Wok
- Bistrorante Midi
- McDonald's
- Advena Europa Hotel
- GuestHouse Mainz
- Terminus
- Hotel Moguntia
- McDonald's
- Cafe Extrablatt
- Hans im Glück
- The Big Easy
- Hyatt Regency Mainz
- Favorite Parkhotel
- Ibis Hotel Mainz City
- Hof Ehrenfels
- Zum Laubenheimer Ried - Da Giovanni
- Mainzer Hof
- Pizza Roma
- Bäckerei Werner
- Goldene Ente
Most popular train connections from Karlsruhe
More options for your journey from Karlsruhe to Mainz
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