The cheapest and fastest buses from Düsseldorf to Lyon
Cheapest price
$60
Average price
$81
Fastest journey
15 h
Average duration
15 h 41 m
Buses per day
11
Distance
625 km
The best way to find a cheap bus ticket from Düsseldorf to Lyon is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Düsseldorf to Lyon will cost around $81 if you buy it on the day, but the cheapest tickets can be found for only $60.
It's difficult to get from Düsseldorf to Lyon without transferring at least once.
50429 · 50617
FlixBus · FlixBus
50449 · 94765
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
50429 · 50617Travel Information
Compare train, bus, and flight for Düsseldorf to Lyon
Omio recommends booking the bus as it is the most popular option from Düsseldorf to Lyon among Omio's users. If you are prioritising price take the bus with prices starting from $39. For those with little time consider booking a flight which can get you there in 2h 20m. The ticket price range depends on the travel mode: a bus costs an average of $39, and a flight costs an average of $92.
Distance: 388 miles (625 km)
Compare bus with
Most popular Bus | Train | Flight |
|---|---|---|
$68 Average price Cheapest | $239 Average price | $255 Average price |
12h 43m Average total duration 12h 13m Onboard + 30m Additional time* | 6h 57m Average total duration 6h 27m Onboard + 30m Additional time* | 5h 20m Average total duration Fastest 2h 20m Onboard + 3h 0m Additional time* |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Düsseldorf to Lyon Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 03:45AM | Arrival Time 08:35PM | Duration 16h50 | Departure days Mon, Wed, Sat, Sun | Cheapest price $63 |
Operator FlixBus | Departure Time 06:35AM | Arrival Time 11:50PM | Duration 17h15 | Departure days Tue, Wed | Cheapest price $63 |
Operator BlaBlaCar | Departure Time 07:00AM | Arrival Time 03:30PM | Duration 8h30 | Departure days Sun | Cheapest price $47 |
Operator FlixBus | Departure Time 07:15AM | Arrival Time 11:15PM | Duration 16h00 | Departure days Mon, Sat, Sun | Cheapest price $64 |
Operator FlixBus | Departure Time 07:55AM | Arrival Time 02:00AM | Duration 18h05 | Departure days Mon, Tue, Wed, Sat, Sun | Cheapest price $64 |
Operator FlixBus | Departure Time 08:31AM | Arrival Time 04:45AM | Duration 20h14 | Departure days Mon, Sun | Cheapest price $65 |
Operator BlaBlaCar | Departure Time 09:00AM | Arrival Time 06:00PM | Duration 9h00 | Departure days Wed | Cheapest price $62 |
Operator FlixBus | Departure Time 09:27AM | Arrival Time 04:45AM | Duration 19h18 | Departure days Sat | Cheapest price $97 |
Operator FlixBus | Departure Time 10:20AM | Arrival Time 04:35AM | Duration 18h15 | Departure days Mon, Sat, Sun | Cheapest price $65 |
Operator BlaBlaCar Bus | Departure Time 10:40AM | Arrival Time 03:30AM | Duration 16h50 | Departure days Mon, Tue, Wed, Sat, Sun | Cheapest price $49 |
Operator FlixBus | Departure Time 11:26AM | Arrival Time 05:20AM | Duration 17h54 | Departure days Sun | Cheapest price $168 |
Operator FlixBus | Departure Time 01:45PM | Arrival Time 04:45AM | Duration 15h00 | Departure days Mon, Tue, Wed, Sat, Sun | Cheapest price $62 |
Operator FlixBus | Departure Time 02:25PM | Arrival Time 08:15AM | Duration 17h50 | Departure days Sat, Sun | Cheapest price $82 |
Operator FlixBus | Departure Time 04:21PM | Arrival Time 10:30AM | Duration 18h09 | Departure days Sun | Cheapest price $119 |
Operator FlixBus | Departure Time 05:40PM | Arrival Time 10:30AM | Duration 16h50 | Departure days Mon, Sat, Sun | Cheapest price $65 |
Operator BlaBlaCar | Departure Time 06:50PM | Arrival Time 03:00AM | Duration 8h10 | Departure days Fri | Cheapest price $79 |
Operator FlixBus | Departure Time 09:15PM | Arrival Time 12:50PM | Duration 15h35 | Departure days Fri, Sat | Cheapest price $74 |
Operator BlaBlaCar Bus | Departure Time 09:45PM | Arrival Time 02:40PM | Duration 16h55 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $49 |
Live departures
Düsseldorf to Lyon bus times
The table below shows live departures for Düsseldorf to Lyon buses for today, Friday, February 27. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 8:15 PM Düsseldorf, ZOB am Hbf | 15h35 | 11:50 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan) | 1 transfer | |
50449 · 94765 | 8:45 PM Düsseldorf, ZOB am Hbf | 16h55 | 1:40 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan) | 1 transfer | |
| Saturday, February 28 | |||||
FlixBus · FlixBus | 2:45 AM Düsseldorf, ZOB am Hbf | 16h50 | 7:35 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan) | 1 transfer | |
FlixBus · FlixBus | 6:15 AM Düsseldorf, ZOB am Hbf | 16h00 | 10:15 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan) | 1 transfer | |
FlixBus · FlixBus | 6:55 AM Düsseldorf, ZOB am Hbf | 17h15 | 12:10 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan) | 1 transfer | |
FlixTrain+ FlixBus · FlixBus | 8:27 AM Düsseldorf Hbf | 19h18 | 3:45 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan) | 2 transfers | |
FlixBus · FlixBus | 9:20 AM Düsseldorf, ZOB am Hbf | 15h00 | 12:20 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan) | 1 transfer | |
50429 · 50617 | 9:40 AM Düsseldorf, ZOB am Hbf | 16h50 | 2:30 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan) | 1 transfer | |
FlixBus · FlixBus | 12:45 PM Düsseldorf, ZOB am Hbf | 15h00 | 3:45 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan) | 1 transfer | |
FlixBus · FlixBus | 1:25 PM Düsseldorf, ZOB am Hbf | 17h50 | 7:15 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan) | 1 transfer | |
FlixBus · FlixBus | 4:40 PM Düsseldorf, ZOB am Hbf | 16h50 | 9:30 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Düsseldorf to Lyon by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Feb 27
Feb 28
Mar 01
Mar 02
Mar 03
Mar 04
Mar 05
Mar 06
Mar 07
Mar 08
Mar 09
Mar 10
Mar 11
Mar 12
Mar 13
Mar 14
Mar 15
Mar 16
Mar 17
Mar 18
Mar 19
Why should you book Düsseldorf to Lyon buses with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of BlaBlaCar Bus to find the best option for your trip from Düsseldorf to Lyon.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Düsseldorf to Lyon.
Why book with Omio over Wanderu, Trainline or Checkmybus?
- Compare with other providers: On Omio, you can also compare tickets for the likes of BlaBlaCar Bus to find the best option for your trip from Düsseldorf to Lyon.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Düsseldorf to Lyon.
Journey information
Overview: Bus from Düsseldorf to Lyon
Buses from Düsseldorf to Lyon run on average 6 times per day, taking around 12h 13m. Cheap bus tickets for this journey start at $39 (€31) if you book in advance.
There are 1 buses per day. The earliest bus runs at 00:05, the last at 23:55. The fastest bus covers the 388 miles (625 km) distance in 10h 45m.
Distance 388 miles (625 km) |
Average bus duration 12h 13m |
Cheapest ticket price $39 (€31) |
Buses per day 6 |
Direct buses 1 |
Fastest bus 10h 45m |
First bus 00:05 |
Last bus 23:55 |
Bus providers: FlixBus, BlaBlaCar Bus, BlaBlaCar from Düsseldorf to LyonYou can travel by bus between Düsseldorf to Lyon with FlixBus, BlaBlaCar Bus, BlaBlaCar for as low as $39 (€31). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
BlaBlaCar Bus
BlaBlaCar
FAQs: Bus from Düsseldorf to Lyon
Find answers to the most common questions about traveling from Düsseldorf to Lyon by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Lyon, this guide helps you travel smarter and with confidence.

- BlaBlaCar Bus
- Assistance
- Priority boarding
- Accessible seating options.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Basilica of Notre-Dame de Fourvière, a stunning 19th-century basilica offering panoramic views of the city
- Vieux Lyon, a UNESCO World Heritage site known for its Renaissance architecture and narrow cobblestone streets
- Parc de la Tête d'Or, a large urban park featuring a zoo, botanical garden, and lake
- Musée des Confluences, a modern science and anthropology museum with innovative exhibits
- Place Bellecour, one of Europe's largest open squares, ideal for shopping and dining.
- Les Halles de Lyon Paul Bocuse, a renowned indoor market offering gourmet food and local specialties
- Take a river cruise on the Rhône and Saône for a unique view of the city
- Explore the traboules, secret passageways in Vieux Lyon
- Attend a performance at the Opéra de Lyon, known for its diverse program
- Visit the Institut Lumière, dedicated to the history of cinema.
- BlaBlaCar Bus
- You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- BlaBlaCar Bus
- One carry-on bag up to 7kg and one checked bag up to 20kg.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- BlaBlaCar Bus
- Additional luggage can be purchased for a fee.
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Düsseldorf to Lyon
- 05:00-23:00
- Free Wi-Fi
- Cafeteria im ZOB (in the station)
- Brauerei Schumacher (0.5 km)
- Pizzeria Trattoria Romantica (0.7 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 725, 738, 752, 754, 834 Metro: U75, U78, U79 Train: S1, S6, S11
- 06:00-23:00
- Free Wi-Fi
- Café de la Gare (in the station)
- Le Bistrot de Lyon (0.5 km)
- Brasserie Georges (0.6 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: C19, C20, 31, 46, 49, 55, 60, S1 Metro: A Tram: T1, T2
Most popular bus connections from Düsseldorf
More options for your journey from Düsseldorf to Lyon
Here are some other resources that might have the information you need



