- Must visit
Musée des Beaux-Arts de Lyon
Major fine arts museum in a former abbey, with strong collections from antiquity to modern art. A core cultural stop in Lyon.
Cheapest price
$90
Average price
$109
Fastest journey
10 h 45 m
Average duration
14 h 59 m
Buses per day
5
Distance
625 km
The best way to find a cheap bus ticket from Düsseldorf to Lyon is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Düsseldorf to Lyon will cost around $109 if you buy it on the day, but the cheapest tickets can be found for only $90.
Of the 5 buses that leave Düsseldorf for Lyon on Wed, Jul 15, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, Jul 15 the direct buses cover the 625 km distance in an average of 14 h 59 m but if you time it right, some buses will get you there in just 10 h 45 m .
On Wed, Jul 15 the slowest buses will take 17 h 25 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus
FlixBus · FlixBus
50429 · 83133
50449 · 94765
FlixBus · FlixBus
FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
50449 · 94765
50429 · 83133Omio recommends booking the bus as it is the most popular option from Düsseldorf to Lyon among Omio's users. If you are prioritising price take the bus with prices starting from $45. For those with little time consider booking a flight which can get you there in 2h 21m. The ticket price range depends on the travel mode: a bus costs an average of $45, and a flight costs an average of $79.
Distance: 388 miles (625 km)
Most popular Bus | Train | Flight | Driving |
|---|---|---|---|
$69 Average price Cheapest | $260 Average price | $293 Average price | $188 Average price (fuel + tolls) |
12h 40m Average total duration 12h 10m Onboard + 30m Additional time* | 6h 51m Average total duration 6h 21m Onboard + 30m Additional time* | 5h 21m Average total duration Fastest 2h 21m Onboard + 3h 0m Additional time* | 8h 29m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Düsseldorf to Lyon:
A bus is $190 (€157) less than a train for this route with tickets for a train from Düsseldorf to Lyon costing on average $260 (€214).
A bus is $224 (€185) less than a flight for this route with tickets for a flight from Düsseldorf to Lyon costing on average $293 (€242).
Other travel options to Lyon take longer:
Train takes on average 6h 21m.
Bus takes on average 12h 10m.
Tickets start at around $69 (€57) compared to roughly $188 (€155) in fuel and tolls — a saving of about $119 (€98). The journey takes 12h 10m versus 8h 29m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by FlixBus, BlaBlaCar.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator BlaBlaCar | Departure Time 07:00AM | Arrival Time 02:40PM | Duration 7h40 | Departure days Mon, Wed | Cheapest price $49 |
Operator BlaBlaCar Bus | Departure Time 08:15AM | Arrival Time 12:20AM | Duration 16h05 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $61 |
Operator FlixBus | Departure Time 10:35AM | Arrival Time 01:45AM | Duration 15h10 | Departure days Wed, Thu, Fri, Sat, Sun | Cheapest price $90 |
Operator BlaBlaCar Bus | Departure Time 10:40AM | Arrival Time 04:05AM | Duration 17h25 | Departure days Everyday | Cheapest price $85 |
Operator FlixBus | Departure Time 01:00PM | Arrival Time 04:35AM | Duration 15h35 | Departure days Sat, Sun | Cheapest price $99 |
Operator BlaBlaCar | Departure Time 02:10PM | Arrival Time 10:20PM | Duration 8h10 | Departure days Wed | Cheapest price $69 |
Operator FlixBus | Departure Time 02:25PM | Arrival Time 05:05AM | Duration 14h40 | Departure days Everyday | Cheapest price $90 |
Operator FlixBus | Departure Time 05:25PM | Arrival Time 08:15AM | Duration 14h50 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $89 |
Operator BlaBlaCar Bus | Departure Time 09:45PM | Arrival Time 02:40PM | Duration 16h55 | Departure days Everyday | Cheapest price $75 |
Operator FlixBus | Departure Time 11:00PM | Arrival Time 09:45AM | Duration 10h45 | Departure days Everyday | Cheapest price $79 |
The table below shows live departures for Düsseldorf to Lyon buses for today, Tuesday, July 14. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
50429 · 5807 | 10:40 AM Düsseldorf, ZOB am Hbf | 17h50 | 4:30 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus · FlixBus | 2:25 PM Düsseldorf, ZOB am Hbf | 14h40 | 5:05 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus · FlixBus | 5:25 PM Düsseldorf, ZOB am Hbf | 14h50 | 8:15 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
50449 · 5131 | 9:45 PM Düsseldorf, ZOB am Hbf | 21h05 | 6:50 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus | 11:00 PM Düsseldorf, ZOB am Hbf | 10h45 | 9:45 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect |
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Düsseldorf to Lyon run on average 6 times per day, taking around 12h 10m. Cheap bus tickets for this journey start at $45 (€37) if you book in advance.
There are 1 buses per day. The earliest bus runs at 00:05, the last at 23:55. The fastest bus covers the 388 miles (625 km) distance in 10h 45m.
Distance 388 miles (625 km) |
Average bus duration 12h 10m |
Cheapest ticket price $45 (€37) |
Buses per day 6 |
Direct buses 1 |
Fastest bus 10h 45m |
First bus 12:05 AM |
Last bus 11:55 PM |
Cheapest Month Sep |
Cheapest Day Mon |
High Season Oct - Dec |
Low Season Apr - Jun |
Busiest Day Tue |
Least Busy Day Sat |
Best time to book 84 days |
Discover the best of Lyon — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Lyon trip today.
Major fine arts museum in a former abbey, with strong collections from antiquity to modern art. A core cultural stop in Lyon.
Museum of cinema miniatures and film props in Vieux Lyon. Popular for detailed sets, special-effects history, and family-friendly exhibits.
Excellent free natural history and ethnography museum with fossils, animals, and global cultures. A strong local favorite, especially for families.
Renaissance quarter with cobbled lanes, traboules, courtyards, and major monuments. Essential for atmosphere, history, and walking exploration.
Central peninsula between the Rhône and Saône, packed with elegant streets, squares, shopping, and many of Lyon’s classic city views.
Historic silk-workers’ hill district with stairways, murals, markets, and hidden passageways. Great for local character and city panoramas.
Pike dumplings in a rich crayfish sauce. A Lyon classic from traditional bouchons, prized for its delicate fish texture and luxurious sauce.
Crisp salad of frisée, bacon lardons, croutons, and a poached egg. A staple Lyonnaise bistro dish that reflects the city's hearty cooking style.
Slow-cooked onions with vinegar, often served warm or chilled. This old Lyonnais side dish is traditional in bouchons and pairs well with charcuterie.
Refined dining by Paul Bocuse, known for polished French cuisine and iconic Lyon dishes in an elegant, historic dining room.
Well-known traditional bouchon in Vieux Lyon, praised for generous Lyonnais specialties and a lively old-city atmosphere.
Historic bouchon near Place Bellecour serving quenelles, salade lyonnaise, and classic regional fare in a warm traditional setting.
Moderate for Western Europe: hotels and dining are mid-priced, while public transport is good value for visitors.
Service is usually included. Round up or leave 5-10% for great restaurant service. Round up taxi fares; small change is fine in cafes.
Find answers to the most common questions about traveling from Düsseldorf to Lyon by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Lyon, this guide helps you travel smarter and with confidence.

Most Düsseldorf to Lyon buses use the Düsseldorf, ZOB am Hbf to Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan) station pair, with some services arriving at Lyon, Gare Routière de Perrache. Use this guide to compare Düsseldorf and Lyon bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Düsseldorf, ZOB am Hbf is 1 km from Düsseldorf city centre. Public transport options include:
Düsseldorf, ZOB am Hbf has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria im ZOB (in the station), Brauerei Schumacher (0.5 km), Pizzeria Trattoria Romantica (0.7 km).
Free Wi-Fi. ATMs are located near the main entrance and throughout the station.
Ticket office support is available at Düsseldorf, ZOB am Hbf.
Available at Düsseldorf, ZOB am Hbf: Parking, Taxis, WC.
Accessibility facilities are available at Düsseldorf, ZOB am Hbf: Elevators, ramps.
Lyon, Gare Routière de Perrache is 1 km from Lyon city centre. Public transport options include:
Lyon, Gare Routière de Perrache has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Café de la Gare (in the station), Le Bistrot de Lyon (0.5 km), Brasserie Georges (0.6 km).
Free Wi-Fi. ATMs are located near the main entrance.
Ticket office support is available at Lyon, Gare Routière de Perrache.
Available at Lyon, Gare Routière de Perrache: Parking, Taxis, WC.
Accessibility facilities are available at Lyon, Gare Routière de Perrache: Elevators, ramps.
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