Travel Information
Compare bus, flight, and train for Syracuse, NY to Indianapolis, IN
Omio recommends booking the train as it is the most popular option from Syracuse, NY to Indianapolis, IN among Omio's users. If you are prioritising price take the train with prices starting from $178. For those with little time consider booking a flight which can get you there in 5h 27m. The ticket price range depends on the travel mode: a train costs an average of $178, and a flight costs an average of $283.
Distance: 565 miles (910 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
$209 Average price | $190 Average price Cheapest | $378 Average price |
22h 50m Average total duration 22h 20m Onboard + 30m Additional time* | 18h 31m Average total duration 18h 1m Onboard + 30m Additional time* | 8h 27m Average total duration Fastest 5h 27m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Syracuse, NY to Indianapolis, IN Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 03:55AM | Arrival Time 04:10AM | Duration 24h15 | Departure days Thu | Cheapest price $166 |
Operator FlixBus | Departure Time 04:30AM | Arrival Time 03:00AM | Duration 22h30 | Departure days Thu | Cheapest price $176 |
Operator Greyhound | Departure Time 09:25AM | Arrival Time 09:30AM | Duration 24h05 | Departure days Thu | Cheapest price $170 |
Operator Greyhound | Departure Time 09:00PM | Arrival Time 03:00AM | Duration 30h00 | Departure days Thu | Cheapest price $179 |
Live departures
Syracuse, NY to Indianapolis, IN bus times
The table below shows live departures for Syracuse, NY to Indianapolis, IN buses for tomorrow, Thursday, April 2. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
undefined · undefined · undefined+ FlixBus | 1:00 AM Syracuse, Walsh Cir (Syracuse Bus Station), NY | 30h00 | 7:00 AM Indianapolis, E Washington St / N Delaware St (City/County Building), IN | 3 transfers | |
undefined · undefined | 1:00 AM Syracuse, Walsh Cir (Syracuse Bus Station), NY | 21h40 | 10:40 PM Indianapolis, Illinois St (Greyhound Bus Station) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Syracuse, NY to Indianapolis, IN by bus, flight, or train
Compare bus, flight, and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Syracuse, NY to Indianapolis, IN buses with Omio?
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, flight and train to ensure you get the best deal for traveling from Syracuse, NY to Indianapolis, IN.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus, flight and train to find the ideal travel option from Syracuse, NY to Indianapolis, IN.
Journey information
Overview: Bus from Syracuse, NY to Indianapolis, IN
Buses from Syracuse, NY to Indianapolis, IN run on average 4 times per day, taking around 22h 20m. Cheap bus tickets for this journey start at $149 (€121) if you book in advance.
The earliest bus runs at 00:15, the last at 23:55. The fastest bus covers the 565 miles (910 km) distance in 21h 40m.
Distance 565 miles (910 km) |
Average bus duration 22h 20m |
Cheapest ticket price $149 (€121) |
Buses per day 4 |
Fastest bus 21h 40m |
First bus 12:15 AM |
Last bus 11:55 PM |
Bus providers: Greyhound from Syracuse, NY to Indianapolis, INYou can travel by bus between Syracuse, NY to Indianapolis, IN with Greyhound for as low as $149 (€121). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from Syracuse, NY to Indianapolis, IN
Find answers to the most common questions about traveling from Syracuse, NY to Indianapolis, IN by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Indianapolis, IN, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Indianapolis Motor Speedway, a historic racing circuit known for hosting the Indianapolis 500
- The Children's Museum of Indianapolis, the world's largest children's museum featuring interactive exhibits
- Indianapolis Zoo, a popular attraction with diverse animal exhibits and a botanical garden
- Indiana State Museum, showcasing the state's history, art, and science through various exhibits
- White River State Park, a sprawling urban park offering trails, gardens, and cultural attractions.
- Indianapolis Museum of Art at Newfields, a vast art museum with extensive collections and beautiful gardens
- Attend a race at the Indianapolis Motor Speedway, home of the iconic Indy 500
- Explore the interactive exhibits and educational programs at The Children's Museum of Indianapolis
- Visit the dolphin pavilion and animal habitats at the Indianapolis Zoo
- Enjoy a walk along the canal and cultural attractions at White River State Park.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Syracuse, NY to Indianapolis, IN
More options for your journey from Syracuse, NY to Indianapolis, IN
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