The cheapest and fastest buses from Syracuse, NY to Indianapolis, IN
Cheapest price
$89
Average price
$102
Fastest journey
22 h 30 m
Average duration
22 h 45 m
Buses per day
2
Distance
910 km
The best way to find a cheap bus ticket from Syracuse, NY to Indianapolis, IN is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Syracuse, NY to Indianapolis, IN will cost around $102 if you buy it on the day, but the cheapest tickets can be found for only $89.
Of the 2 buses that leave Syracuse, NY for Indianapolis, IN on Tue, Feb 17, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Tue, Feb 17 the direct buses cover the 910 km distance in an average of 22 h 45 m but if you time it right, some buses will get you there in just 22 h 30 m .
On Tue, Feb 17 the slowest buses will take 23 h and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Travel Information
Compare bus and flight for Syracuse, NY to Indianapolis, IN
Omio recommends booking the flight as it is the most popular option from Syracuse, NY to Indianapolis, IN among Omio's users. If you are prioritising price take the train with prices starting from €164. For those with little time consider booking a flight which can get you there in 5h 34m. The ticket price range depends on the travel mode: a train costs an average of €164, and a flight costs an average of €230.
Distance: 565 miles (910 km)
Compare bus with
| Bus | Most popular Flight | Train |
|---|---|---|
€170 Average price | €310 Average price | €164 Average price Cheapest |
22h 50m Average total duration 22h 20m Onboard + 30m Additional time* | 8h 34m Average total duration Fastest 5h 34m Onboard + 3h 0m Additional time* | 18h 31m Average total duration 18h 1m Onboard + 30m Additional time* |
Direct Options | Direct Options | Direct Options |
Syracuse, NY to Indianapolis, IN Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 01:15AM | Arrival Time 04:10AM | Duration 26h55 | Departure days Thu | Cheapest price $166 |
Operator FlixBus | Departure Time 04:30AM | Arrival Time 03:00AM | Duration 22h30 | Departure days Thu | Cheapest price $166 |
Operator Greyhound | Departure Time 09:00PM | Arrival Time 06:40PM | Duration 21h40 | Departure days Thu | Cheapest price $156 |
Live departures
Syracuse, NY to Indianapolis, IN bus times
The table below shows live departures for Syracuse, NY to Indianapolis, IN buses for today, Monday, February 16. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 9:35 PM Syracuse, NY | 23h00 | 8:35 PM Indianapolis, IN | 0 transfersDirect | |
| Tuesday, February 17 | |||||
![]() | 8:30 AM Syracuse, NY | 22h30 | 7:00 AM Indianapolis, IN | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Syracuse, NY to Indianapolis, IN by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Feb 17
Feb 18
Feb 19
Feb 20
Feb 21
Feb 22
Feb 23
Why should you book Syracuse, NY to Indianapolis, IN buses with Omio?
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of to find the best option for your trip from Syracuse, NY to Indianapolis, IN.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Syracuse, NY to Indianapolis, IN.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Syracuse, NY to Indianapolis, IN.
Journey information
Overview: Bus from Syracuse, NY to Indianapolis, IN
Buses from Syracuse, NY to Indianapolis, IN run on average 4 times per day, taking around 22h 20m. Cheap bus tickets for this journey start at $157 (€125) if you book in advance.
The earliest bus runs at 00:15, the last at 23:55. The fastest bus covers the 565 miles (910 km) distance in 21h 40m.
Distance 565 miles (910 km) |
Average bus duration 22h 20m |
Cheapest ticket price $157 (€125) |
Buses per day 4 |
Fastest bus 21h 40m |
First bus 00:15 |
Last bus 23:55 |
Bus providers: Greyhound from Syracuse, NY to Indianapolis, INYou can travel by bus between Syracuse, NY to Indianapolis, IN with Greyhound for as low as $157 (€125). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from Syracuse, NY to Indianapolis, IN
Find answers to the most common questions about traveling from Syracuse, NY to Indianapolis, IN by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Indianapolis, IN, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Indianapolis Motor Speedway, a historic racing circuit known for hosting the Indianapolis 500
- The Children's Museum of Indianapolis, the world's largest children's museum featuring interactive exhibits
- Indianapolis Zoo, a popular attraction with diverse animal exhibits and a botanical garden
- Indiana State Museum, showcasing the state's history, art, and science through various exhibits
- White River State Park, a sprawling urban park offering trails, gardens, and cultural attractions.
- Indianapolis Museum of Art at Newfields, a vast art museum with extensive collections and beautiful gardens
- Attend a race at the Indianapolis Motor Speedway, home of the iconic Indy 500
- Explore the interactive exhibits and educational programs at The Children's Museum of Indianapolis
- Visit the dolphin pavilion and animal habitats at the Indianapolis Zoo
- Enjoy a walk along the canal and cultural attractions at White River State Park.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Syracuse, NY to Indianapolis, IN
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