- Must visit
The Children's Museum of Indianapolis
The world's largest children's museum, known for large-scale interactive exhibits spanning science, culture, dinosaurs, and space. A top family attraction in the city.
2,000+ travel companies
2,000+ travel companies
Scan to get our free app
Use our app to get live travel updates and book mobile tickets for trains, buses, flights, and ferries.
App Store
4.942K ratings
Google Play
4.6136K reviews
Travel Information
Compare bus, train, and flight for Syracuse, NY to Indianapolis, IN
Omio recommends booking the train as it is the most popular option from Syracuse, NY to Indianapolis, IN among Omio's users. If you are prioritising price take the bus with prices starting from $121. For those with little time consider booking a flight which can get you there in 6h 4m. The ticket price range depends on the travel mode: a bus costs an average of $121, and a flight costs an average of $341.
Distance: 565 miles (910 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
$176 Average price Cheapest | $249 Average price | $425 Average price |
22h 50m Average total duration 22h 20m Onboard + 30m Additional time* | 18h 30m Average total duration 18h 0m Onboard + 30m Additional time* | 9h 4m Average total duration Fastest 6h 4m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Syracuse, NY to Indianapolis, IN is a bus with an average price of $176 (€142).
This is compared to other travel options from Syracuse, NY to Indianapolis, IN:
A bus is $73 (€59) less than a train for this route with tickets for a train from Syracuse, NY to Indianapolis, IN costing on average $249 (€201).
A bus is $249 (€202) less than a flight for this route with tickets for a flight from Syracuse, NY to Indianapolis, IN costing on average $425 (€344).
The fastest way to travel from Syracuse, NY to Indianapolis, IN is by flight with an average journey time of 6h 4m.
Other travel options to Indianapolis, IN take longer:
Train takes on average 18h 0m.
Bus takes on average 22h 20m.
It's helpful to compare your options as there are 3 ways to travel between Syracuse, NY and Indianapolis, IN including taking a bus, train, and flight.
We recommend using the train as it is the most popular way to get from Syracuse, NY to Indianapolis, IN among Omio's users.
Syracuse, NY to Indianapolis, IN Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 01:00AM | Arrival Time 07:00AM | Duration 30h00 | Departure days Wed, Sat | Cheapest price $128 |
Operator Greyhound | Departure Time 02:00AM | Arrival Time 11:40PM | Duration 21h40 | Departure days Fri | Cheapest price $150 |
Operator Greyhound | Departure Time 02:30AM | Arrival Time 04:10AM | Duration 25h40 | Departure days Mon | Cheapest price $122 |
Operator FlixBus | Departure Time 04:30AM | Arrival Time 03:00AM | Duration 22h30 | Departure days Mon | Cheapest price $120 |
Operator Greyhound | Departure Time 06:30AM | Arrival Time 08:10AM | Duration 25h40 | Departure days Thu | Cheapest price $123 |
Operator Greyhound | Departure Time 08:00AM | Arrival Time 09:10AM | Duration 25h10 | Departure days Wed | Cheapest price $261 |
Operator FlixBus | Departure Time 08:30AM | Arrival Time 07:00AM | Duration 22h30 | Departure days Wed, Thu | Cheapest price $146 |
Operator Greyhound | Departure Time 08:35AM | Arrival Time 09:20AM | Duration 24h45 | Departure days Mon | Cheapest price $128 |
Operator Greyhound | Departure Time 12:30PM | Arrival Time 01:30PM | Duration 25h00 | Departure days Fri | Cheapest price $165 |
Operator Greyhound | Departure Time 01:25PM | Arrival Time 01:30PM | Duration 24h05 | Departure days Wed | Cheapest price $121 |
Operator Greyhound | Departure Time 07:35PM | Arrival Time 04:35PM | Duration 21h00 | Departure days Mon | Cheapest price $120 |
Compare prices and tickets Syracuse, NY to Indianapolis, IN by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Sun
May 24
May 24
Mon
May 25
May 25
Tue
May 26
May 26
Wed
May 27
May 27
Thu
May 28
May 28
Fri
May 29
May 29
Sat
May 30
May 30
Why should you book Syracuse, NY to Indianapolis, IN buses with Omio?
Greyhound operates all buses services from Syracuse, NY to Indianapolis, IN.
Omio is an official ticket reseller for all your travel options from Syracuse, NY to Indianapolis, IN.
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Syracuse, NY to Indianapolis, IN.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Syracuse, NY to Indianapolis, IN.
Journey information
Overview: Bus from Syracuse, NY to Indianapolis, IN
USAUSA
Buses from Syracuse, NY to Indianapolis, IN run on average 4 times per day, taking around 22h 20m. Cheap bus tickets for this journey start at $121 (€98) if you book in advance.
The earliest bus runs at 00:15, the last at 23:30. The fastest bus covers the 565 miles (910 km) distance in 21h 40m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 565 miles (910 km) |
Average bus duration 22h 20m |
Cheapest ticket price $121 (€98) |
Buses per day 4 |
Fastest bus 21h 40m |
First bus 12:15 AM |
Last bus 11:30 PM |
Cheapest Month Sep |
Cheapest Day Mon |
High Season Jul - Sep |
Low Season Oct - Dec |
Best time to book 21 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: Greyhound from Syracuse, NY to Indianapolis, INYou can travel by bus between Syracuse, NY to Indianapolis, IN with Greyhound for as low as $121 (€98). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
21h 40m
Cheapest Price
$121 (€98)
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Complete guide to Indianapolis
Things to do in Indianapolis
Discover the best of Indianapolis — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Indianapolis trip today.
- Must visit
Newfields: Indianapolis Museum of Art
A major art museum with broad collections, rotating exhibitions, and landscaped grounds. One of Indianapolis's most important cultural institutions.
- Recommended
Eiteljorg Museum
Celebrated museum of Native American and Western art, with strong permanent collections and thoughtful interpretation. Distinctive and highly regarded downtown stop.
- Must visit
Monument Circle
Indianapolis's signature central circle and public gathering place, surrounded by historic buildings and anchored by the Soldiers and Sailors Monument.
- Must visit
Massachusetts Avenue
Popular cultural corridor lined with theaters, public art, nightlife, and independent shops. One of the city's trendiest walking areas.
- Must visit
Canal Walk
Scenic downtown promenade along the Central Canal, popular for walking, photos, and skyline views. Widely featured in visitor guides and social media.
Pork Tenderloin Sandwich
A Hoosier classic: a breaded and fried pork cutlet served on a bun, often comically larger than the bread. It is one of Central Indiana’s most iconic comfort foods.
- Vegetarian
Sugar Cream Pie
Indiana’s unofficial state pie, made with a rich custard-like filling of cream, sugar, and vanilla, often with a caramelized top. It is a long-standing regional dessert tradition.
- Gluten-free
St. Elmo Shrimp Cocktail
Indianapolis is famous for this fiery shrimp cocktail served with an exceptionally hot horseradish sauce, popularized by the historic St. Elmo Steak House.
Bluebeard
Well-regarded modern American restaurant in Fletcher Place with a creative seasonal menu, strong local following, and stylish yet relaxed setting.
St. Elmo Steak House
Historic downtown steakhouse best known for its shrimp cocktail, steaks, and classic old-school atmosphere. One of Indianapolis’s most famous dining institutions.
Harry & Izzy's
Established upscale-casual spot related to St. Elmo, known for steaks, seafood, and the famous shrimp cocktail in a polished but approachable atmosphere.
United States Dollar
Generally moderate by U.S. standards. Hotels vary by events, while casual dining, coffee, and local transport are fairly affordable.
Average meal costs
- Budget
- USD 10-15 for fast food or a simple lunch.
- Mid-range
- USD 20-40 per person at a casual sit-down restaurant.
- Fine dining
- USD 60+ per person at upscale restaurants.
- Coffee
- USD 3-6 for drip coffee or a latte.
Tipping culture
Tip 18-20% at restaurants, 15-20% for taxis and rideshares, USD 1-2 per bag for hotel staff, and USD 1-2 per drink at bars. Tipping is expected for table service.
FAQs: Bus from Syracuse, NY to Indianapolis, IN
Find answers to the most common questions about traveling from Syracuse, NY to Indianapolis, IN by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Indianapolis, IN, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Syracuse, NY to Indianapolis, IN can start from as little as $121 (€98) when you book in advance. The average bus ticket price for Syracuse, NY to Indianapolis, IN is $176 (€142) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Syracuse, NY to Indianapolis, IN is 21h 40m to travel the 565 miles (910 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Syracuse, NY to Indianapolis, IN leaves at 12:15 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Syracuse, NY to Indianapolis, IN leaves at 11:30 PM.
There are 4 buses a day from Syracuse, NY to Indianapolis, IN which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Syracuse, NY to Indianapolis, IN, you can count on Greyhound for the best way to get you to Indianapolis, IN. You can also check all possible bus companies who offer a service between Syracuse, NY and Indianapolis, IN and compare the amenities they offer before buying a bus ticket.
A trip to Indianapolis, IN from Syracuse, NY is worth doing but not as a day trip with a journey time of 21h 40m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Syracuse, NY to Indianapolis, IN is September.
It's helpful to compare your options as there are 3 ways to travel between Syracuse, NY and Indianapolis, IN including taking a bus, train, and flight.
Yes, the following accessibility options are available when taking the bus from Syracuse, NY to Indianapolis, IN:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Syracuse, NY to Indianapolis, IN for bus company Greyhound.
Some of the most interesting sights to explore in Indianapolis, IN are:
- Indianapolis Motor Speedway, a historic racing circuit known for hosting the Indianapolis 500
- The Children's Museum of Indianapolis, the world's largest children's museum featuring interactive exhibits
- Indianapolis Zoo, a popular attraction with diverse animal exhibits and a botanical garden
- Indiana State Museum, showcasing the state's history, art, and science through various exhibits
- White River State Park, a sprawling urban park offering trails, gardens, and cultural attractions.
The best things to do in Indianapolis, IN include:
- Indianapolis Museum of Art at Newfields, a vast art museum with extensive collections and beautiful gardens
- Attend a race at the Indianapolis Motor Speedway, home of the iconic Indy 500
- Explore the interactive exhibits and educational programs at The Children's Museum of Indianapolis
- Visit the dolphin pavilion and animal habitats at the Indianapolis Zoo
- Enjoy a walk along the canal and cultural attractions at White River State Park.
Whether you can cancel your bus ticket from Syracuse, NY to Indianapolis, IN depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Syracuse, NY to Indianapolis, IN.
Yes, the following luggage options are included when booking a bus ticket from Syracuse, NY to Indianapolis, IN:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Syracuse, NY to Indianapolis, IN:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Syracuse, NY to Indianapolis, IN.
You can reserve your seat on the bus from Syracuse, NY to Indianapolis, IN with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Syracuse, NY to Indianapolis, IN with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Syracuse, NY to Indianapolis, IN with the following bus company: Greyhound.
Since neither Syracuse, NY nor Indianapolis, IN are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the train as it is the most popular way to get from Syracuse, NY to Indianapolis, IN among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Indianapolis, travelers should be cautious of pickpocketing and vehicle break-ins, especially in busy areas like downtown and near major event venues. Common scams include overcharging by unofficial taxi or rideshare drivers and distraction tactics used to steal belongings. It's advised to use authorized transportation services, avoid poorly lit or unfamiliar areas at night, and keep valuables secure.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Syracuse, NY to Indianapolis, IN
Syracuse
Indianapolis
The major bus station for departures in Syracuse is Syracuse, Walsh Cir (Syracuse Bus Station). Find all the information you need to know about services, amenities and connections at Syracuse, Walsh Cir (Syracuse Bus Station) for your trip from Syracuse to Indianapolis.
Syracuse, Walsh Cir (Syracuse Bus Station)
information
The major bus station for arrivals in Indianapolis is Indianapolis, Illinois St (Greyhound Bus Station). Find all the information you need to know about services, amenities and connections at Indianapolis, Illinois St (Greyhound Bus Station) for your trip to Indianapolis from Syracuse.
Indianapolis, Illinois St (Greyhound Bus Station)
information
Indianapolis, E Washington St / N Delaware St (City/County Building)
information
More options for your journey from Syracuse, NY to Indianapolis, IN
Here are some other resources that might have the information you need
Most popular buses to and from Indianapolis, IN and Syracuse, NY
Most popular bus connections to Indianapolis, IN
The Omio App Makes Travel Planning Easy
We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.
