Syracuse, NY SYR to Indianapolis, IN IND flight with Republic Airlines

Thu, Feb 05
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Journey information

Overview: Syracuse, NY to Indianapolis, IN flight

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Flights from Syracuse, NY to Indianapolis, IN depart on average 42 times per day, taking around 5h 34m. Cheap flight tickets for this journey start at $289 (€230) but you can travel from only $157 (€125) by bus.

The earliest flight runs at 05:05, the last at 21:31. The fastest flight covers the 565 miles (910 km) distance in 4h 11m. May is the cheapest month to fly.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $157 (€125)
Distance
565 miles (910 km)
Average flight duration
5h 34m
Cheapest ticket price
$289 (€230)
Flights per day
42
Fastest flight
4h 11m
Cheapest month to travel
May
First flight
05:05
Last flight
21:31
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $157 (€125)

The cheapest and fastest flights from Syracuse, NY to Indianapolis, IN

Showing times and prices for Feb 06

Cheapest price

$295

Average price

$295

Fastest journey

4 h 2 m

Average duration

4 h 2 m

Flights per day

1

Distance

910 km

Cheap tickets

The best way to find a cheap flight ticket from Syracuse, NY to Indianapolis, IN is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Syracuse, NY to Indianapolis, IN will cost around $295 if you buy it on the day, but the cheapest tickets can be found for only $295.

Fast flights

Of the 1 flights that leave Syracuse, NY for Indianapolis, IN onFri, Feb 06, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.

On Fri, Feb 06 the direct flights cover the 910 km distance in an average of 4 h 2 m but if you time it right, some flights will get you there in just 4 h 2 m .

On Fri, Feb 06 the longest flights will take 4 h 2 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

United
02:30PM4h02
Syracuse, NY
06:32PMIndianapolis, IN
$2951One-way
0 transfers

Travel Information

Compare bus and flight for Syracuse, NY to Indianapolis, IN

Omio recommends booking the bus as it is the most popular option from Syracuse, NY to Indianapolis, IN among Omio's users. If you are prioritising price take the train with prices starting from €164. For those with little time consider booking a flight which can get you there in 5h 34m. The ticket price range depends on the travel mode: a train costs an average of €164, and a flight costs an average of €230.

Distance: 565 miles (910 km)

Compare flight with

Flight
Most popular
Bus
Train

€310

Average price

€170

Average price

€164

Average price

Cheapest

8h 34m

Average total duration

Fastest

5h 34m

Onboard

+

3h 0m

Additional time*

22h 50m

Average total duration

22h 20m

Onboard

+

30m

Additional time*

18h 31m

Average total duration

18h 1m

Onboard

+

30m

Additional time*

Direct Options

Direct Options

Direct Options

Compare prices and tickets Syracuse, NY to Indianapolis, IN by bus or flight

Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Fri
Feb 06
Sat
Feb 07
Sun
Feb 08
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Feb 09
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Feb 11
Thu
Feb 12

Airlines: Republic Airlines from Syracuse, NY to Indianapolis, INFind the best flights between Syracuse, NY to Indianapolis, IN with Omio's travel partners Republic Airlines from $157 (€125). We can find you the best deals, schedules and tickets when comparing and booking the best trip.

Republic Airlines

About
Republic Airways is a major regional airline in the United States, operating as a subsidiary of Republic Airways Holdings. It provides scheduled passenger service for American Airlines (as American Eagle), Delta Air Lines (as Delta Connection), and United Airlines (as United Express) using a fleet of Embraer 170 and 175 regional jets. Headquartered in Indianapolis, Indiana, Republic Airways operates over 900 daily flights to more than 80 cities across the U.S. and Canada. The company is known for its large fleet of Embraer E-Jets and its state-of-the-art training facilities. In April 2025, Republic Airways Holdings announced its acquisition of Mesa Air Group, which is expected to create the second-largest regional carrier in the U.S.
Luggage & cancellation policy
Average Duration
6h 3m
Cheapest Price
$497 (€396)
Republic Airlines frequency
6 a day
Luggage included
One carry-on bag (24 x 16 x 10) and one personal item
Additional luggage
Checked bags for a fee
Cancellation Policy
Tickets are non-refundable but may be cancelled for future flight credit minus applicable fees
Pregnant on board
Passengers can fly up to the end of their 36th week for single pregnancies and the end of their 32nd week for multiple pregnancies
Unaccompagned minor
Unaccompanied minor service is available for children ages 5-14. Must be booked directly with Republic Airlines
Amenities on board the airplane
USB plugs
Accessibility
Republic Airlines offers assistance for passengers with reduced mobility, including wheelchair services and priority boarding. Passengers are advised to request these services in advance to ensure availability and proper arrangements.

FAQs: Syracuse, NY to Indianapolis, IN Flight

Find answers to the most common questions about traveling from Syracuse, NY to Indianapolis, IN by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Indianapolis, IN, this guide helps you travel smarter and with confidence.

FAQs
Cheap plane tickets from Syracuse, NY to Indianapolis, IN can start from as little as $289 (€230) when you book in advance. The average flight ticket price for Syracuse, NY to Indianapolis, IN is $390 (€310) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by plane from Syracuse, NY to Indianapolis, IN is 4h 11m to travel the 565 miles (910 km) long route. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest flight from Syracuse, NY to Indianapolis, IN leaves at 5:05 AM. Plan your trip with the Journey Planner from Omio.
The latest flight from Syracuse, NY to Indianapolis, IN leaves at 9:31 PM.
There are 42 flights a day from Syracuse, NY to Indianapolis, IN which require at least one change with Republic Airlines. Schedules can vary on holidays or weekends with fewer flights.
When taking a flight from Syracuse, NY to Indianapolis, IN, you can count on Republic Airlines for the best way to get you to Indianapolis, IN. You can also check all possible airlines who offer a service between Syracuse, NY and Indianapolis, IN and compare the amenities they offer before buying a plane ticket.
Flights from Syracuse, NY to Indianapolis, IN generally leave from Syracuse Hancock International Airport and arrive in Indianapolis International Airport.Syracuse Hancock International Airport is 1 miles (2 km) away from Syracuse, NY city centre and Indianapolis International Airport is 4 miles (8 km) from Indianapolis, IN city centre.
The cheapest month for a flight from Syracuse, NY to Indianapolis, IN is May.
It's helpful to compare your options as there are 2 ways to travel between Syracuse, NY and Indianapolis, IN including taking a bus and flight.
Since neither Syracuse, NY nor Indianapolis, IN are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
There is no time difference between Syracuse, NY and Indianapolis, IN.
The best events to attend in Indianapolis, IN include:
  • Indy 500, the iconic automobile race held annually on Memorial Day weekend, attracting racing fans from around the world
  • Indiana State Fair, a beloved summer tradition featuring agricultural exhibits, live entertainment, and delicious local food
  • Gen Con, one of the largest tabletop gaming conventions in North America, offering a vibrant atmosphere for gamers and enthusiasts alike.
The best holidays to experience in Indianapolis, IN include:
  • Independence Day, vibrant fireworks and festive parades celebrating American heritage
  • Labor Day, pleasant weather perfect for outdoor activities and local events
  • Thanksgiving, a time for family gatherings with a cozy atmosphere and fewer crowds.
The best season to visit Indianapolis, IN is Spring or Fall. The best weather to explore Indianapolis, IN is during April-May or September-October.
For domestic flights we recommend to arrive 1.5 to 2 hours before departure. Please check the website of your departure airport if in doubt. Some airports may offer booking time slots for security checks or offer additional information on when to get there based on time of day.
Most airlines permit carry-on bags that fit within specific dimensions (e.g., 22 x 14 x 9 inches or 56 x 36 x 23 cm), including handles and wheels. Bags must fit in the overhead bin or under the seat in front of you.
Many airlines impose weight limits, commonly ranging between 7 kg (15 lbs) and 12 kg (26 lbs). Typically, passengers are allowed one carry-on bag and one personal item (for example a purse, laptop bag, or backpack). Personal items must fit under the seat in front of you. Budget Airlines (like Ryanair or Wizz Air) have stricter size and weight limits, often requiring fees for larger carry-ons. Full-Service Airlines have more lenient policies, sometimes including more spacious dimensions or higher weight limits depending on your ticket class.
The list of items prohibited on an airplane varies by country and airline, but in general, the following items are not allowed in carry-on or checked baggage: Weapons and self-defence items, sharp objects, flammable materials, explosives, toxic substances, or liquids over 100ml (except for medications and baby essentials). In checked baggage, firearms (without authorization), explosives, large lithium batteries, and hazardous chemicals are prohibited. Electronic cigarettes must be in carry-on bags, while alcohol and dry ice have restrictions. Always check with your airline for specific regulations.

popular airports

Popular airports from Syracuse, NY to Indianapolis, IN

Syracuse
Indianapolis
The major airport for departures in Syracuse is Syracuse Hancock International Airport. Find all the information you need to know about services, amenities and connections at Syracuse Hancock International Airport for your trip from Syracuse to Indianapolis.
Amenities at airport
WifiWifi
ShoppingShopping
ParkingParking
DiningDining
ATMATM
TaxisTaxis
AccessibilityAccessibility
WCWC
LoungeLounge
Lost and Found OfficeLost and Found Office
Car RentalCar Rental
information
ticketOfficeHours
Distance to city center
2 km
carConnection
Car connection
I-81, exit 27
Wifi
Wifi
  • Free Wi-Fi available throughout the airport.
Shopping
Shopping
  • Shops include Hudson News and other convenience stores in the terminal.
Parking
Parking
  • Parking available, approximately 1.9€ ($2) per hour.
Dining
Dining
  • Restaurants are available, including Dunkin' Donuts and Johnny Rockets in the terminal.
Taxis
Taxis
  • Available outside the terminal.
Accessibility
Accessibility
  • Elevators, ramps
WC
WC
  • Available throughout the airport.
Lounge
Lounge
  • Lounge access available for eligible passengers, including the Military Courtesy Room.
Lost and Found Office
Lost and Found Office
  • Lost and Found located in the main terminal near baggage claim.
Car Rental
Car Rental
  • Car rental services are available on-site with companies like Hertz and Avis.
Public transit options for Syracuse Hancock International Airport
  • Centro Bus Route 51, SYR Airport Stop, 8 km

Most popular flights from Syracuse, NY

More options for your journey from Syracuse, NY to Indianapolis, IN

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Most popular flights to and from Indianapolis, IN and Syracuse, NY

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