Travel Information
Compare bus and flight for Syracuse, NY to Indianapolis, IN
Omio recommends booking the flight as it is the most popular option from Syracuse, NY to Indianapolis, IN among Omio's users. If you are prioritising price take the bus with prices starting from €69. For those with little time consider booking a flight which can get you there in 3h 54m. The ticket price range depends on the travel mode: a bus costs an average of €69, and a flight costs an average of €160.
Distance: 565 miles (910 km)
Compare flight with
Most popular Flight | Bus |
|---|---|
€228 Average price | €104 Average price Cheapest |
6h 54m Average total duration Fastest 3h 54m Onboard + 3h 0m Additional time* | 22h 50m Average total duration 22h 20m Onboard + 30m Additional time* |
![]() Most popular airline | ![]() Most popular bus company |
Direct Options | Direct Options |
Live departures
Syracuse, NY to Indianapolis, IN train times
The table below shows live departures for Syracuse, NY to Indianapolis, IN trains for tomorrow, Thursday, February 5. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
449 Lake Shore Limited · 50 Cardinal | 3:05 AM Syracuse Station, Syracuse, NY | 25h44 | 4:49 AM Indianapolis Station, Indianapolis, IN | 1 transfer | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Syracuse, NY to Indianapolis, IN by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Feb 05
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Journey information
Overview: Train from Syracuse, NY to Indianapolis, IN
Take a train from Syracuse, NY to Indianapolis, IN and enjoy the approximately 565 miles (910 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
The earliest train runs at 06:00, the last at 22:05.
Distance 565 miles (910 km) |
Trains per day 1 |
First train 06:00 |
Last train 22:05 |
FAQs: Trains from Syracuse, NY to Indianapolis, IN
Find answers to the most common questions about traveling from Syracuse, NY to Indianapolis, IN by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Indianapolis, IN, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Syracuse, NY to Indianapolis, IN
- 6:00 AM - 10:00 PM Monday - Sunday
- Parking is available at the station.
- Dinosaur Bar-B-Que
- The Mission Restaurant
- Outside the main entrance.
- $1
- Embassy Suites by Hilton Syracuse
- Comfort Inn & Suites Airport
- Best Western Syracuse Downtown Hotel and Suites
- Located in the main hall
- Enterprise
- Located in the main hall
- Free
- Hall 1: main entrance, ticket office, and waiting area
- Hall 2: platforms for Amtrak and bus services
- Bus: Centro Bus Service
- Taxi: Available outside the station
- 6:00 AM - 11:00 PM Monday - Sunday
- Free
- Parking is available a few blocks away from the station.
- Harry & Izzy's
- St. Elmo Steak House
- Outside the main entrance.
- Ramps.
- Free for passengers
- Crowne Plaza Indianapolis-Dwtn-Union-Stn
- Omni Severin Hotel
- The Westin Indianapolis
- Located in the main hall
- Free
- Hall 1: main entrance, platform for Amtrak's Cardinal line
- Bus: IndyGo routes available nearby
More options for your journey from Syracuse, NY to Indianapolis, IN
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