- Must visit
Cleveland Museum of Art
A world-class art museum known for its diverse collection spanning ancient to contemporary works. It is one of Cleveland’s signature cultural attractions and a top priority for most visitors.
Cheapest
+
St. Louis, S 15th St (Civic center)
Cleveland, Chester Ave At the Greyhound Station (South Side)
$1101•One-way
2nd cheapest, Fastest
+St. Louis, S 15th St (Civic center)
Cleveland, Chester Ave At the Greyhound Station (South Side)
$1321•One-way
The cheapest and fastest busesfrom St. Louis, MO to Cleveland, OHShowing times and prices for Jul 10
Cheapest price
$110
Average price
$121
Fastest journey
19h 45m
Average duration
21h 18m
Buses per day
2
Distance
657 km
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St. Louis, MO to Cleveland, OH bus with Greyhound
Travel Information
Compare train, bus, and flight for St. Louis, MO to Cleveland, OH
Omio recommends booking the flight as it is the most popular option from St. Louis, MO to Cleveland, OH among Omio's users. If you are prioritising price take the bus with prices starting from $88. For those with little time consider booking a flight which can get you there in 6h 5m. The ticket price range depends on the travel mode: a bus costs an average of $88, and a train costs an average of $97.
Distance: 490 miles (790 km)
Compare bus with
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
$145 Average price Cheapest | $266 Average price | $289 Average price | $112 Average price (fuel + tolls) |
18h 29m Average total duration 17h 59m Onboard + 30m Additional time* | 9h 5m Average total duration Fastest 6h 5m Onboard + 3h 0m Additional time* | 18h 2m Average total duration 17h 32m Onboard + 30m Additional time* | 8h 24m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
The cheapest way to travel from St. Louis, MO to Cleveland, OH is a bus with an average price of $145 (€119).
This is compared to other travel options from St. Louis, MO to Cleveland, OH:
A bus is $121 (€99) less than a flight for this route with tickets for a flight from St. Louis, MO to Cleveland, OH costing on average $266 (€218).
A bus is $144 (€118) less than a train for this route with tickets for a train from St. Louis, MO to Cleveland, OH costing on average $289 (€237).
The fastest way to travel from St. Louis, MO to Cleveland, OH is by flight with an average journey time of 6h 5m.
Other travel options to Cleveland, OH take longer:
Train takes on average 17h 32m.
Bus takes on average 17h 59m.
It's helpful to compare your options as there are 3 ways to travel between St. Louis, MO and Cleveland, OH including taking a train, bus, and flight.
We recommend using the bus as it is the most popular way to get from St. Louis, MO to Cleveland, OH among Omio's users.
Take the bus. On this route, it's both cheaper and quicker than driving.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
St. Louis, MO to Cleveland, OH Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 02:00AM | Arrival Time 08:15PM | Duration 17h15 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $80 |
Operator Greyhound | Departure Time 08:45AM | Arrival Time 04:20AM | Duration 18h35 | Departure days Everyday | Cheapest price $79 |
Operator Greyhound | Departure Time 01:55PM | Arrival Time 10:25AM | Duration 19h30 | Departure days Everyday | Cheapest price $82 |
Operator Greyhound | Departure Time 04:00PM | Arrival Time 03:50PM | Duration 22h50 | Departure days Everyday | Cheapest price $82 |
Operator FlixBus | Departure Time 11:30PM | Arrival Time 08:15PM | Duration 19h45 | Departure days Mon, Wed, Fri, Sat, Sun | Cheapest price $82 |
Live departures
St. Louis, MO to Cleveland, OH bus times
The table below shows live departures for St. Louis, MO to Cleveland, OH buses for today, Friday, July 10. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
 FlixBus+ · | 4:00 PM St. Louis, S 15th St (Civic center) | 22h50 | 3:50 PM Cleveland, Chester Ave At the Greyhound Station (South Side) | 2 transfers | |
| FlixBus++FlixBus | 11:30 PM St. Louis, S 15th St (Civic center) | 19h45 | 8:15 PM Cleveland, Chester Ave At the Greyhound Station (South Side) | 2 transfers | |
| Saturday, July 11 | |||||
| · +FlixBus | 2:00 AM St. Louis, S 15th St (Civic center) | 17h15 | 8:15 PM Cleveland, Chester Ave At the Greyhound Station (South Side) | 2 transfers | |
| · | 8:45 AM St. Louis, S 15th St (Civic center) | 18h35 | 4:20 AM Cleveland, Chester Ave At the Greyhound Station (South Side) | 1 transfer | |
| · · | 1:55 PM St. Louis, S 15th St (Civic center) | 19h30 | 10:25 AM Cleveland, Chester Ave At the Greyhound Station (South Side) | 2 transfers | |
Find all the dates and times for this journey
Compare prices and tickets St. Louis, MO to Cleveland, OH by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book St. Louis, MO to Cleveland, OH buses with Omio?
Greyhound operates all buses services from St. Louis, MO to Cleveland, OH.
Omio is an official ticket reseller for all your travel options from St. Louis, MO to Cleveland, OH.
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from St. Louis, MO to Cleveland, OH.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from St. Louis, MO to Cleveland, OH.
Journey information
Overview: Bus from St. Louis, MO to Cleveland, OH
USAUSA
Buses from St. Louis, MO to Cleveland, OH run on average 5 times per day, taking around 17h 59m. Cheap bus tickets for this journey start at $88 (€73) if you book in advance.
The earliest bus runs at 02:00, the last at 23:30. The fastest bus covers the 490 miles (790 km) distance in 15h 30m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 490 miles (790 km) |
Average bus duration 17h 59m |
Cheapest ticket price $88 (€73) |
Buses per day 5 |
Fastest bus 15h 30m |
First bus 2:00 AM |
Last bus 11:30 PM |
Cheapest Month Jul |
Cheapest Day Wed |
High Season Jan - Mar |
Low Season Jul - Sep |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: Greyhound from St. Louis, MO to Cleveland, OHYou can travel by bus between St. Louis, MO to Cleveland, OH with Greyhound for as low as $88 (€73). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
15h 30m
Cheapest Price
$96 (€79)
Greyhound frequency
1 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Complete guide to Cleveland
Things to do in Cleveland
Discover the best of Cleveland — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Cleveland trip today.
- Must visit
Rock & Roll Hall of Fame
An iconic museum on the lakefront celebrating the history and impact of rock music through major artifacts, exhibitions, and interactive displays. It is one of the city’s most famous attractions.
- Recommended
Great Lakes Science Center
A hands-on science museum with family-friendly exhibits, technology displays, and a NASA Glenn Visitor Center area. It is especially popular with families and curious learners.
- Must visit
Public Square
The symbolic center of downtown Cleveland, surrounded by major buildings and public monuments. It is a natural starting point for walking and sightseeing.
- Must visit
University Circle
Cleveland’s premier cultural district, home to major museums, gardens, and historic institutions. It is one of the city’s best areas for a full day of exploration.
- Must visit
Ohio City
A lively historic neighborhood known for preserved architecture, independent businesses, and strong local character. It remains one of the city’s most popular walkable areas.
Polish Boy
Cleveland’s signature sandwich: a kielbasa sausage topped with fries, barbecue sauce, and coleslaw on a bun. It reflects the city’s Eastern European and soul food influences.
- Vegetarian
Pierogi
Dumplings filled with potato, cheese, sauerkraut, or meat, strongly tied to Cleveland’s large Polish and Central European communities. A local comfort food found at festivals and neighborhood diners.
Lake Erie Perch
Lightly breaded or pan-fried yellow perch from Lake Erie, a regional favorite often served as a sandwich or plated fish fry. It is one of Northeast Ohio’s classic seafood dishes.
Pier W
A long-established fine dining seafood restaurant with Lake Erie views. Known for polished service, fresh fish, and a classic special-occasion atmosphere.
Slyman's Restaurant Cleveland
An iconic Cleveland deli best known for towering corned beef sandwiches. Casual, busy, and classic, it is one of the city’s most famous lunch spots.
Rowley Inn
A respected Tremont tavern serving comfort food and local favorites, including a popular Polish Boy. Relaxed neighborhood setting with historic Cleveland charm.
United States Dollar
Generally moderate for U.S. city travel. Hotels vary by season, while casual dining and local transport are reasonably priced.
Average meal costs
- Budget
- USD 10-18 for fast food or a simple lunch.
- Mid-range
- USD 20-40 per person at a mid-range restaurant.
- Fine dining
- USD 60+ per person at upscale restaurants.
- Coffee
- USD 3-6 for a coffee drink.
Tipping culture
Tip 18-20% in restaurants before tax. Tip USD 1-2 per drink at bars, round up or tip 10-15% for taxis, and tip hotel staff and delivery drivers.
FAQs: Bus from St. Louis, MO to Cleveland, OH
Find answers to the most common questions about traveling from St. Louis, MO to Cleveland, OH by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Cleveland, OH, this guide helps you travel smarter and with confidence.
Cheap bus tickets from St. Louis, MO to Cleveland, OH can start from as little as $88 (€73) when you book in advance. The average bus ticket price for St. Louis, MO to Cleveland, OH is $145 (€119) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from St. Louis, MO to Cleveland, OH is 15h 30m to travel the 490 miles (790 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from St. Louis, MO to Cleveland, OH leaves at 2:00 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from St. Louis, MO to Cleveland, OH leaves at 11:30 PM.
There are 5 buses a day from St. Louis, MO to Cleveland, OH which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from St. Louis, MO to Cleveland, OH, you can count on Greyhound for the best way to get you to Cleveland, OH. You can also check all possible bus companies who offer a service between St. Louis, MO and Cleveland, OH and compare the amenities they offer before buying a bus ticket.
A trip to Cleveland, OH from St. Louis, MO is worth doing but not as a day trip with a journey time of 15h 30m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from St. Louis, MO to Cleveland, OH is July.
It's helpful to compare your options as there are 3 ways to travel between St. Louis, MO and Cleveland, OH including taking a train, bus, and flight.
Yes, there are bathrooms on board the bus from St. Louis, MO to Cleveland, OH for bus company Greyhound.
Yes, the following accessibility options are available when taking the bus from St. Louis, MO to Cleveland, OH:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Whether you can cancel your bus ticket from St. Louis, MO to Cleveland, OH depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from St. Louis, MO to Cleveland, OH.
Yes, the following luggage options are included when booking a bus ticket from St. Louis, MO to Cleveland, OH:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from St. Louis, MO to Cleveland, OH:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from St. Louis, MO to Cleveland, OH.
You can reserve your seat on the bus from St. Louis, MO to Cleveland, OH with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from St. Louis, MO to Cleveland, OH with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from St. Louis, MO to Cleveland, OH with the following bus company: Greyhound.
Since neither St. Louis, MO nor Cleveland, OH are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the train as it is the most popular way to get from St. Louis, MO to Cleveland, OH among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Cleveland, OH, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like downtown and popular attractions. Avoid poorly lit or isolated neighborhoods at night. Common scams include fake ticket sellers near sports venues and overcharging by unlicensed taxi or rideshare drivers. Staying alert and using official transportation options enhances safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from St. Louis, MO to Cleveland, OH
Most St. Louis, MO to Cleveland, OH buses use the St. Louis, S 15th St (Civic center) to Cleveland, Chester Ave At the Greyhound Station (South Side) station pair. Use this guide to compare St. Louis, MO and Cleveland, OH bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in St. Louis
Arrival bus stations in Cleveland
St. Louis, S 15th St (Civic center)
City-centre transport
Getting to St. Louis, S 15th St (Civic center) from St. Louis city centre
TrainMlb, Mlr · 4m · $4 · every ~14 min
Bus19, 32, 40 · 8m · $1 · every ~9 min
Cleveland, Chester Ave At the Greyhound Station (South Side)
City-centre transport
Getting to Cleveland, Chester Ave At the Greyhound Station (South Side) from Cleveland city centre
BusHl · 15m · $4 · every ~10 min
Hl · 16m · $4 · every ~10 min
Most popular bus connections from St. Louis, MO
More options for your journey from St. Louis, MO to Cleveland, OH
Here are some other resources that might have the information you need
Most popular buses to and from Cleveland, OH and St. Louis, MO
Most popular bus connections to Cleveland, OH
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