- Must visit
Saint Louis Art Museum
Vast art museum in Forest Park with global collections from antiquity to modern works and strong free general admission.
Cheapest price on Aug 30
$66
Average ticket price on Aug 30
$80
Fastest journey on Aug 30
9 h 15 m
Average journey duration on Aug 30
12 h 11 m
Buses on Aug 30
4
Distance
495 km
The best way to find a cheap bus ticket from Cincinnati, OH to St. Louis, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Cincinnati, OH to St. Louis, MO will cost around $80 if you buy it on the day, but the cheapest tickets can be found for only $66.
It's difficult to get from Cincinnati, OH to St. Louis, MO without transferring at least once.
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· · Omio recommends booking the bus as it is the most popular option from Cincinnati, OH to St. Louis, MO among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $64 For those with little time, consider booking a bus, which has an average total journey time of 7h 8m. Average ticket prices depend on the travel mode: a bus costs an average of $64, while a train costs an average of $187.
Distance: 307 miles (495 km)
Most popular Bus | Train | Driving |
|---|---|---|
$64 Average price Cheapest | $187 Average price | $72 Average price (fuel + tolls) |
7h 8m Average total duration Fastest 6h 38m Onboard + 30m Additional time* | 21h 16m Average total duration 20h 46m Onboard + 30m Additional time* | 5h 6m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Cincinnati, OH to St. Louis, MO:
A bus is $123 (€100) less than a train for this route with tickets for a train from Cincinnati, OH to St. Louis, MO costing on average $187 (€151).
Other travel options to St. Louis, MO take longer:
Train takes on average 20h 46m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:55AM | Arrival Time 03:10PM | Duration 15h15 | Departure days Everyday | Cheapest price $57 |
Operator Greyhound | Departure Time 10:05AM | Arrival Time 11:15PM | Duration 14h10 | Departure days Everyday | Cheapest price $57 |
Operator Greyhound | Departure Time 02:10PM | Arrival Time 11:15PM | Duration 10h05 | Departure days Everyday | Cheapest price $59 |
Operator Greyhound | Departure Time 03:00PM | Arrival Time 11:15PM | Duration 9h15 | Departure days Everyday | Cheapest price $59 |
The table below shows live departures for Cincinnati, OH to St. Louis, MO buses for tomorrow, Sunday, August 30. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
· · | 12:55 AM Cincinnati, Greyhound Bus Station, OH | 15h15 | 3:10 PM St. Louis, S 15th St (Civic center) | 2 transfers | |
· · | 10:05 AM Cincinnati, Greyhound Bus Station, OH | 14h10 | 11:15 PM St. Louis, S 15th St (Civic center) | 2 transfers | |
FlixBus+![]() | 2:10 PM Cincinnati, Gilbert Ave (Greyhound Bus Station), OH | 10h05 | 11:15 PM St. Louis, S 15th St (Civic center) | 1 transfer | |
FlixBus+![]() | 3:00 PM Cincinnati, Short Vine St (University of Cincinnati), OH | 9h15 | 11:15 PM St. Louis, S 15th St (Civic center) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Cincinnati, OH to St. Louis, MO run on average 4 times per day, taking around 6h 38m. Cheap bus tickets for this journey start at $49 (€40) if you book in advance.
The earliest bus runs at 00:55, the last at 23:45. The fastest bus covers the 307 miles (495 km) distance in 9h 15m.
Distance 307 miles (495 km) |
Average bus duration 6h 38m |
Cheapest ticket price $49 (€40) |
Buses per day 4 |
Fastest bus 9h 15m |
First bus 12:55 AM |
Last bus 11:45 PM |
Cheapest Month Feb |
Cheapest Day Thu |
High Season Jul - Sep |
Low Season Oct - Dec |
Best time to book 14 days |
Discover the best of St. Louis, MO — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect St. Louis, MO trip today.
Vast art museum in Forest Park with global collections from antiquity to modern works and strong free general admission.
Leading history museum covering St. Louis, Missouri, and national stories through rotating exhibitions in Forest Park.
Interactive science museum with hands-on exhibits, planetarium, and family-friendly displays near Forest Park.
Lively downtown riverfront district with trails, views of the Arch, public art, and access to major historic sites.
Large urban park with trails, lakes, zoo access, and major museums, ideal for walking between top attractions.
Beloved neighborhood park with formal lily ponds, pavilions, and one of the city's most photographed landscapes.
A thin, cracker-like crust pizza cut into squares and topped with Provel cheese, a St. Louis original loved for its distinct texture and tangy flavor.
Crisp, breaded ravioli said to be born on The Hill, usually served with marinara. It is a signature St. Louis Italian-American appetizer.
Sticky butter cake with a dense base and gooey sweet top. A longtime St. Louis bakery favorite often enjoyed for breakfast or dessert.
Refined contemporary restaurant with tasting menus and strong national acclaim. Elegant fine dining focused on seasonal Midwestern ingredients.
Beloved frozen custard stand serving concretes and sundaes since 1929. Casual, nostalgic, and one of the city's iconic dessert stops.
Popular smokehouse known for St. Louis barbecue, especially ribs, brisket, and pork steak, in a polished but relaxed atmosphere.
Moderate for U.S. city breaks: hotels and dining are reasonable, transit is limited, and attractions often cost less than in larger U.S. tourist cities.
Tip 18-20% at restaurants, $1-2 per drink at bars, and 10-15% for taxis. Cafes often have tip jars or screen prompts.
Find answers to the most common questions about traveling from Cincinnati, OH to St. Louis, MO by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.

Most Cincinnati, OH to St. Louis, MO buses use the Cincinnati, Greyhound Bus Station to St. Louis, S 15th St (Civic center) station pair. Use this guide to compare Cincinnati, OH and St. Louis, MO bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Cincinnati, Greyhound Bus Station is 12 km from Cincinnati city centre. Public transport options include:
Cincinnati, Greyhound Bus Station has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Free Wi-Fi available in the waiting area. ATMs are aTM machines available inside the station.
Ticket office support is available at Cincinnati, Greyhound Bus Station.
Available at Cincinnati, Greyhound Bus Station: Parking, Taxis, WC.
Accessibility facilities are available at Cincinnati, Greyhound Bus Station: Wheelchair accessible entrances and seating available.
Cincinnati, Short Vine St (University of Cincinnati) is 3 km from Cincinnati city centre. Public transport options include:
Cincinnati, Short Vine St (University of Cincinnati) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Restaurants available along Short Vine St.
Wi-Fi is available at Cincinnati, Short Vine St (University of Cincinnati). ATMs are aTMs available in nearby banks.
Ticket office support is available at Cincinnati, Short Vine St (University of Cincinnati).
Available at Cincinnati, Short Vine St (University of Cincinnati): Parking, Taxis, WC.
Accessibility facilities are available at Cincinnati, Short Vine St (University of Cincinnati): Accessible pathways available.
Cincinnati, Gilbert Ave (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Cincinnati, Gilbert Ave (Greyhound Bus Station). ATMs are available at Cincinnati, Gilbert Ave (Greyhound Bus Station).
Ticket office support is available at Cincinnati, Gilbert Ave (Greyhound Bus Station).
Available at Cincinnati, Gilbert Ave (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Cincinnati, Gilbert Ave (Greyhound Bus Station): Wheelchair accessible facility.
St. Louis, S 15th St (Civic center) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at St. Louis, S 15th St (Civic center). ATMs are available at St. Louis, S 15th St (Civic center).
Ticket office support is available at St. Louis, S 15th St (Civic center).
Available at St. Louis, S 15th St (Civic center): Parking, Taxis, WC.
Accessibility facilities are available at St. Louis, S 15th St (Civic center): Wheelchair accessible routes available.
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