- Must visit
Mint Museum Uptown
Major Uptown museum for European, American, and contemporary art. Its collection and architecture make it Charlotte's top fine-arts stop.
2,000+ travel companies
2,000+ travel companies
Scan to get our free app
Use our app to get live travel updates and book mobile tickets for trains, buses, flights, and ferries.
App Store
4.942K ratings
Google Play
4.6136K reviews
The cheapest and fastest buses from St. Louis, MO to Charlotte, NC
Showing times and prices for Aug 06
Cheapest price
$92
Average price
$95
Fastest journey
17 h 35 m
Average duration
18 h 54 m
Buses per day
5
Distance
913 km
Cheap tickets
The best way to find a cheap bus ticket from St. Louis, MO to Charlotte, NC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from St. Louis, MO to Charlotte, NC will cost around $95 if you buy it on the day, but the cheapest tickets can be found for only $92.
Fast buses
It's difficult to get from St. Louis, MO to Charlotte, NC without transferring at least once.
FlixBus+
+FlixBus4:00 PM18h30St. Louis, S 15th St (Civic center)11:30 AMCharlotte, W 4th St (Greyhound Bus Station)$921One-way2 transfers- · · 1:45 PM17h55St. Louis, S 15th St (Civic center)8:40 AMCharlotte, W 4th St (Greyhound Bus Station)$931One-way2 transfers
- · +FlixBus1:00 AM21h25St. Louis, S 15th St (Civic center)11:25 PMCharlotte, W 4th St (Greyhound Bus Station)$931One-way2 transfers
- FlixBus · FlixBus11:45 PM17h35St. Louis, S 15th St (Civic center)6:20 PMCharlotte, W 4th St (Greyhound Bus Station)$931One-way1 transfer
- · 9:00 AM19h05St. Louis, S 15th St (Civic center)5:05 AMCharlotte, W 4th St (Greyhound Bus Station)$1031One-way1 transfer
- FlixBus · FlixBus11:45 PM17h35St. Louis, S 15th St (Civic center)6:20 PMCharlotte, W 4th St (Greyhound Bus Station)$931One-way1 transfer
- · · 1:45 PM17h55St. Louis, S 15th St (Civic center)8:40 AMCharlotte, W 4th St (Greyhound Bus Station)$931One-way2 transfers
- FlixBus++FlixBus4:00 PM18h30St. Louis, S 15th St (Civic center)11:30 AMCharlotte, W 4th St (Greyhound Bus Station)$921One-way2 transfers
- · 9:00 AM19h05St. Louis, S 15th St (Civic center)5:05 AMCharlotte, W 4th St (Greyhound Bus Station)$1031One-way1 transfer
- · +FlixBus1:00 AM21h25St. Louis, S 15th St (Civic center)11:25 PMCharlotte, W 4th St (Greyhound Bus Station)$931One-way2 transfers
Journey information
Overview: Bus from St. Louis, MO to Charlotte, NC
USAUSA
Buses from St. Louis, MO to Charlotte, NC run on average 6 times per day, taking around 25h 34m. Cheap bus tickets for this journey start at $97 if you book in advance.
The earliest bus runs at 00:55, the last at 23:40. The fastest bus covers the 567 miles (913 km) distance in 17h 30m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 567 miles (913 km) |
Average bus duration 25h 34m |
Cheapest ticket price $97 |
Buses per day 6 |
Fastest bus 17h 30m |
First bus 12:55 AM |
Last bus 11:40 PM |
Cheapest Month Jul |
Cheapest Day Fri |
High Season Jan - Mar |
Low Season Jul - Sep |
Best time to book 21 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
St. Louis, MO to Charlotte, NC Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 01:00AM | Arrival Time 11:25PM | Duration 21h25 | Departure days Everyday | Cheapest price $93 |
Operator Greyhound | Departure Time 09:00AM | Arrival Time 05:05AM | Duration 19h05 | Departure days Everyday | Cheapest price $96 |
Operator Greyhound | Departure Time 01:45PM | Arrival Time 08:40AM | Duration 17h55 | Departure days Everyday | Cheapest price $93 |
Operator Greyhound | Departure Time 04:00PM | Arrival Time 11:30AM | Duration 18h30 | Departure days Everyday | Cheapest price $92 |
Operator FlixBus | Departure Time 11:45PM | Arrival Time 06:20PM | Duration 17h35 | Departure days Everyday | Cheapest price $93 |
Live departures
St. Louis, MO to Charlotte, NC bus times
The table below shows live departures for St. Louis, MO to Charlotte, NC buses for today, Wednesday, August 5. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| · | 9:00 AM St. Louis, S 15th St (Civic center) | 19h05 | 5:05 AM Charlotte, W 4th St (Greyhound Bus Station) | 1 transfer | |
| · · | 1:45 PM St. Louis, S 15th St (Civic center) | 17h55 | 8:40 AM Charlotte, W 4th St (Greyhound Bus Station) | 2 transfers | |
| FlixBus++FlixBus | 4:00 PM St. Louis, S 15th St (Civic center) | 18h30 | 11:30 AM Charlotte, W 4th St (Greyhound Bus Station) | 2 transfers | |
| FlixBus · FlixBus | 11:45 PM St. Louis, S 15th St (Civic center) | 17h35 | 6:20 PM Charlotte, W 4th St (Greyhound Bus Station) | 1 transfer | |
| Thursday, August 6 | |||||
| · +FlixBus | 1:00 AM St. Louis, S 15th St (Civic center) | 21h25 | 11:25 PM Charlotte, W 4th St (Greyhound Bus Station) | 2 transfers | |
Find all the dates and times for this journey
Why should you book St. Louis, MO to Charlotte, NC buses with Omio?
Greyhound as well as FlixBus offer buses services from St. Louis, MO to Charlotte, NC.
Omio is an official ticket reseller for all your travel options from St. Louis, MO to Charlotte, NC.
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of FlixBus to find the best option for your trip from St. Louis, MO to Charlotte, NC.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from St. Louis, MO to Charlotte, NC.
Why book with Omio over Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus to find the best option for your trip from St. Louis, MO to Charlotte, NC.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from St. Louis, MO to Charlotte, NC.
Bus providers: Greyhound, FlixBus from St. Louis, MO to Charlotte, NCYou can travel by bus between St. Louis, MO to Charlotte, NC with Greyhound, FlixBus for as low as $97. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
17h 30m
Cheapest Price
$97
FlixBus frequency
1 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
18h 30m
Cheapest Price
$108
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Complete guide to Charlotte, NC
Things to do in Charlotte, NC
Discover the best of Charlotte, NC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Charlotte, NC trip today.
- Must visit
Harvey B. Gantt Center for African-American Arts + Culture
Leading center for African American arts and culture, featuring exhibitions, performances, and powerful stories from Charlotte and beyond.
- Must visit
Discovery Place Science
Regional science museum with hands-on exhibits, live demonstrations, and an IMAX Dome. Great for families and curious adults alike.
- Must visit
Uptown Charlotte
Charlotte's central business district mixes museums, plazas, public art, and skyline views. Essential for first-time visitors exploring the city core.
- Must visit
NoDa
Creative historic district packed with murals, music venues, design shops, and converted mills. Ideal for art, walking, and local culture.
- Must visit
South End
Trendy neighborhood known for rail-trail walking, street art, breweries, and restored industrial spaces. One of Charlotte's liveliest areas.
- Gluten-free
Carolina Pulled Pork Barbecue
Slow-smoked chopped or pulled pork with a tangy vinegar sauce, a Carolina barbecue staple widely loved across Charlotte.
- Gluten-free
Mustard-Sauce Barbecue Pork
Smoky pit-cooked pork shoulder finished with mustard-based sauce, reflecting South Carolina influence common in Charlotte.
Fried Catfish
Deep-fried catfish, often served with hush puppies and slaw. It is a classic Southern comfort dish popular in the Charlotte region.
Midwood Smokehouse
Historic barbecue spot famed for Carolina chopped pork, red slaw, and old-school Southern atmosphere.
Haberdish
Lively Southern dining room serving fried chicken, biscuits, shrimp and grits, and regional cocktails in South End.
The Asbury
Refined Southern restaurant in Uptown known for shrimp and grits, local ingredients, and an elegant modern setting.
United States Dollar ($)
Moderate for a major U.S. city. Hotels and dining are mid-priced, transit is affordable, and attractions often cost less than in larger hubs like New York or San Francisco.
Average meal costs
- Budget
- $10-15 for fast food or casual takeaway.
- Mid-range
- $20-40 per person for a restaurant meal.
- Fine dining
- $75+ per person for upscale restaurants.
- Coffee
- $4-6 for a cappuccino or latte.
Tipping culture
Tip 18-20% at restaurants, 15-20% for taxis, and $1-2 per drink or coffee in cafes if service is provided.
FAQs: Bus from St. Louis, MO to Charlotte, NC
Find answers to the most common questions about traveling from St. Louis, MO to Charlotte, NC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Charlotte, NC, this guide helps you travel smarter and with confidence.
Cheap bus tickets from St. Louis, MO to Charlotte, NC can start from as little as $97 when you book in advance. The average bus ticket price for St. Louis, MO to Charlotte, NC is $188 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from St. Louis, MO to Charlotte, NC is 17h 30m to travel the 567 miles (913 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from St. Louis, MO to Charlotte, NC leaves at 12:55 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from St. Louis, MO to Charlotte, NC leaves at 11:40 PM.
There are 6 buses a day from St. Louis, MO to Charlotte, NC which require at least one change with Greyhound, FlixBus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from St. Louis, MO to Charlotte, NC, you can count on Greyhound, FlixBus for the best way to get you to Charlotte, NC. You can also check all possible bus companies who offer a service between St. Louis, MO and Charlotte, NC and compare the amenities they offer before buying a bus ticket.
When departing from St. Louis, MO , you have various bus station options to start your journey from including St. Louis, S 15th St (Civic center) . When arriving in Charlotte, NC , you can end your journey in bus stations like Charlotte, W 4th St (Greyhound Bus Station), Charlotte, Freedom Drive (Planet Fitness), NC .Passengers board the bus most frequently from St. Louis, S 15th St (Civic center), which is located around away from the city centre, and they get off the bus at Charlotte, W 4th St (Greyhound Bus Station), located 0 away from the city centre.
It's helpful to compare your options as there are 3 ways to travel between St. Louis, MO and Charlotte, NC including taking a train, bus, and flight.
Yes, the following accessibility options are available when taking the bus from St. Louis, MO to Charlotte, NC:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from St. Louis, MO to Charlotte, NC for bus company Greyhound, FlixBus.
Whether you can cancel your bus ticket from St. Louis, MO to Charlotte, NC depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company Greyhound, FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from St. Louis, MO to Charlotte, NC.
Yes, the following luggage options are included when booking a bus ticket from St. Louis, MO to Charlotte, NC:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from St. Louis, MO to Charlotte, NC:
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from St. Louis, MO to Charlotte, NC. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from St. Louis, MO to Charlotte, NC with the following bus company: Greyhound, FlixBus
Yes, there are USB plugs on board the bus from St. Louis, MO to Charlotte, NC with the following bus company: Greyhound, FlixBus.
Yes, there is Wifi on board the bus from St. Louis, MO to Charlotte, NC with the following bus company: Greyhound, FlixBus.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Charlotte, NC, travelers should be cautious of pickpocketing and vehicle break-ins, especially in crowded areas and parking lots. Common scams include overcharging by unofficial taxi or rideshare drivers and fake ticket sellers near popular attractions. It's advisable to use licensed transportation services and keep valuables secure to avoid these risks.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from St. Louis, MO to Charlotte, NC
Most St. Louis, MO to Charlotte, NC buses use the St. Louis, S 15th St (Civic center) to Charlotte, W 4th St (Greyhound Bus Station) station pair, with some services arriving at Charlotte, Freedom Drive (Planet Fitness). Use this guide to compare St. Louis, MO and Charlotte, NC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in St. Louis
Arrival bus stations in Charlotte
Which St. Louis, MO station do buses to Charlotte, NC leave from?
Buses from St. Louis, MO to Charlotte, NC leave from St. Louis, S 15th St (Civic center). The station is 0 miles (1 km) from St. Louis, MO city centre at S 15th St, St. Louis, MO, USA.
St. Louis, S 15th St (Civic center)S 15th St, St. Louis, MO, USA
City-centre transport
Getting to St. Louis, S 15th St (Civic center) from St. Louis city centre
TrainMlb, Mlr · 4m · $4 · every ~14 min
Bus19, 32, 40 · 8m · $1 · every ~9 min
St. Louis, S 15th St (Civic center) bus station facilities and services
St. Louis, S 15th St (Civic center) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at St. Louis, S 15th St (Civic center). ATMs are available at St. Louis, S 15th St (Civic center).
Tickets and information
Ticket office support is available at St. Louis, S 15th St (Civic center).
Parking, taxis and toilets
Available at St. Louis, S 15th St (Civic center): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at St. Louis, S 15th St (Civic center): Wheelchair accessible routes available.
Which Charlotte, NC station do buses from St. Louis, MO arrive at?
Buses from St. Louis, MO to Charlotte, NC most often arrive at Charlotte, W 4th St (Greyhound Bus Station). Some services arrive at Charlotte, Freedom Drive (Planet Fitness), so check your ticket before travel to confirm your Charlotte, NC arrival station.
Charlotte, W 4th St (Greyhound Bus Station)Charlotte, NC, USA
City-centre transport
Getting to Charlotte, W 4th St (Greyhound Bus Station) from Charlotte city centre
Tram510 · 8m · $4 · every ~5 min
Charlotte, W 4th St (Greyhound Bus Station) bus station facilities and services
Charlotte, W 4th St (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Charlotte, W 4th St (Greyhound Bus Station). ATMs are available at Charlotte, W 4th St (Greyhound Bus Station).
Tickets and information
Ticket office support is available at Charlotte, W 4th St (Greyhound Bus Station).
Parking, taxis and toilets
Available at Charlotte, W 4th St (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Charlotte, W 4th St (Greyhound Bus Station): The station is wheelchair accessible.
Charlotte, Freedom Drive (Planet Fitness)3301 Freedom Dr Ste 600, Charlotte, NC 28208, USA
City-centre transport
Getting to Charlotte, Freedom Drive (Planet Fitness) from Charlotte city centre
Charlotte, Freedom Drive (Planet Fitness) is 5 km from Charlotte city centre. Public transport options include:
Bus8 · 15m · $2 · every ~4 min
34, 8 · 19m · $2 · every ~8 min
Charlotte, Freedom Drive (Planet Fitness) bus station facilities and services
Charlotte, Freedom Drive (Planet Fitness) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Charlotte, Freedom Drive (Planet Fitness). ATMs are available at Charlotte, Freedom Drive (Planet Fitness).
Tickets and information
Ticket office support is available at Charlotte, Freedom Drive (Planet Fitness).
Parking, taxis and toilets
Available at Charlotte, Freedom Drive (Planet Fitness): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Charlotte, Freedom Drive (Planet Fitness): No designated facilities.
Most popular bus connections from St. Louis, MO
More options for your journey from St. Louis, MO to Charlotte, NC
Here are some other resources that might have the information you need
Most popular buses to and from Charlotte, NC and St. Louis, MO
Most popular bus connections to Charlotte, NC
The Omio App Makes Travel Planning Easy
We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.
