St. Louis, MO to Charlotte, NC bus with Greyhound

Sun, Mar 22
+ Add return
Greyhound
FlixBus
Alsa
Costa Verde
BlaBlaCar Bus
2,000+ travel companies
Greyhound
FlixBus
Alsa
Costa Verde
BlaBlaCar Bus
2,000+ travel companies
QR-Code
Scan to get our free app
Use our app to get live travel updates and book mobile tickets for trains, buses, flights, and ferries.
App Store
rate4.9
42K ratings
Google Play
rate4.6
136K reviews

The cheapest and fastest buses from St. Louis, MO to Charlotte, NC

Showing times and prices for Mar 24

Cheapest price

$140

Average price

$172

Fastest journey

18 h 30 m

Average duration

20 h 15 m

Buses per day

3

Distance

913 km

Cheap tickets

The best way to find a cheap bus ticket from St. Louis, MO to Charlotte, NC is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from St. Louis, MO to Charlotte, NC will cost around $172 if you buy it on the day, but the cheapest tickets can be found for only $140.

Fast buses

Of the 3 buses that leave St. Louis, MO for Charlotte, NC on Tue, Mar 24, 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.

On Tue, Mar 24 the direct buses cover the 913 km distance in an average of 20 h 15 m but if you time it right, some buses will get you there in just 18 h 30 m .

On Tue, Mar 24 the slowest buses will take 21 h 50 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

FlixBus
05:30AM20h25
St. Louis, MO
01:55AMCharlotte, NC
$1401One-way
0 transfers
Greyhound
07:00AM21h50
St. Louis, MO
04:50AMCharlotte, NC
$1761One-way
0 transfers
Greyhound
10:00PM18h30
St. Louis, MO
04:30PMCharlotte, NC
$2001One-way
0 transfers

Travel Information

Compare train, bus, and flight for St. Louis, MO to Charlotte, NC

Omio recommends booking the bus as it is the most popular option from St. Louis, MO to Charlotte, NC among Omio's users. If you are prioritising price take the bus with prices starting from $118. For those with little time consider booking a flight which can get you there in 3h 53m. The ticket price range depends on the travel mode: a bus costs an average of $118, and a train costs an average of $312.

Distance: 567 miles (913 km)

Compare bus with

Most popular
Bus
Train
Flight

$187

Average price

Cheapest

$916

Average price

$363

Average price

26h 4m

Average total duration

25h 34m

Onboard

+

30m

Additional time*

32h 22m

Average total duration

31h 52m

Onboard

+

30m

Additional time*

6h 53m

Average total duration

Fastest

3h 53m

Onboard

+

3h 0m

Additional time*

Direct Options

Direct Options

Direct Options

St. Louis, MO to Charlotte, NC Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
Greyhound
Departure Time
01:00AM
Arrival Time
11:50PM
Duration
21h50
Departure days
Sun
Cheapest price
$276
Operator
Greyhound
Departure Time
02:00AM
Arrival Time
05:00AM
Duration
26h00
Departure days
Sun
Cheapest price
$430
Operator
Greyhound
Departure Time
01:45PM
Arrival Time
08:40AM
Duration
17h55
Departure days
Sun
Cheapest price
$265
Operator
Greyhound
Departure Time
04:00PM
Arrival Time
11:30AM
Duration
18h30
Departure days
Sun
Cheapest price
$252

Live departures

St. Louis, MO to Charlotte, NC bus times

The table below shows live departures for St. Louis, MO to Charlotte, NC buses for today, Sunday, March 22. You can also manually refresh the results below to see updated bus journeys.

Last updated at 6:07 AM
ProviderDepartsDurationArrivesTransfers
Tickets
greyhoundundefined · undefined · undefined7:00 AM St. Louis, S 15th St (Civic center)
26h00
9:00 AM Charlotte, W 4th St (Greyhound Bus Station)2 transfers
greyhoundundefined · undefined · undefined6:45 PM St. Louis, S 15th St (Civic center)
17h55
12:40 PM Charlotte, W 4th St (Greyhound Bus Station)2 transfers
meinfernbus_flixbusFlixBus+greyhound+meinfernbus_flixbusFlixBus9:00 PM St. Louis, S 15th St (Civic center)
18h30
3:30 PM Charlotte, W 4th St (Greyhound Bus Station)2 transfers
meinfernbus_flixbusFlixBus+greyhoundundefined · undefined+meinfernbus_flixbusFlixBus9:00 PM St. Louis, S 15th St (Civic center)
25h00
10:00 PM Charlotte, Freedom Drive (Planet Fitness), NC3 transfers
Monday, March 23
meinfernbus_flixbus5:30 AM St. Louis, MO
20h25
1:55 AM Charlotte, NC0 transfersDirect

Find all the dates and times for this journey

Compare prices and tickets St. Louis, MO to Charlotte, NC by train, bus, or flight

Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Mon
Mar 23
Tue
Mar 24
Wed
Mar 25
Thu
Mar 26
Fri
Mar 27
Sat
Mar 28
Sun
Mar 29

Why should you book St. Louis, MO to Charlotte, NC buses with Omio?

Greyhound operates all buses services from St. Louis, MO to Charlotte, NC.
Omio is an official ticket reseller for all your travel options from St. Louis, MO to Charlotte, NC.

Why book with Omio vs Greyhound?

  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from St. Louis, MO to Charlotte, NC.

Why book with Omio over Wanderu?

  • Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from St. Louis, MO to Charlotte, NC.

Journey information

Overview: Bus from St. Louis, MO to Charlotte, NC

USAUSA
USAUSA
Icon of bus

Buses from St. Louis, MO to Charlotte, NC run on average 7 times per day, taking around 25h 34m. Cheap bus tickets for this journey start at $118 (€96) if you book in advance.

The earliest bus runs at 00:55, the last at 23:40. The fastest bus covers the 567 miles (913 km) distance in 17h 30m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
567 miles (913 km)
Average bus duration
25h 34m
Cheapest ticket price
$118 (€96)
Buses per day
7
Fastest bus
17h 30m
First bus
00:55
Last bus
23:40
Cheapest month
Jul
Cheapest day
Sat
High season
Oct - Dec
Low season
Jan - Mar
Best day to book ahead
21 days
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: Greyhound from St. Louis, MO to Charlotte, NCYou can travel by bus between St. Louis, MO to Charlotte, NC with Greyhound for as low as $118 (€96). When you search for schedules and tickets, Omio will show you the best journey

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
17h 55m
Cheapest Price
$147 (€119)
Greyhound frequency
5 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.

FAQs: Bus from St. Louis, MO to Charlotte, NC

Find answers to the most common questions about traveling from St. Louis, MO to Charlotte, NC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Charlotte, NC, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from St. Louis, MO to Charlotte, NC can start from as little as $118 (€96) when you book in advance. The average bus ticket price for St. Louis, MO to Charlotte, NC is $187 (€152) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from St. Louis, MO to Charlotte, NC is 17h 30m to travel the 567 miles (913 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from St. Louis, MO to Charlotte, NC leaves at 12:55 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from St. Louis, MO to Charlotte, NC leaves at 11:40 PM.
There are 7 buses a day from St. Louis, MO to Charlotte, NC which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from St. Louis, MO to Charlotte, NC, you can count on Greyhound for the best way to get you to Charlotte, NC. You can also check all possible bus companies who offer a service between St. Louis, MO and Charlotte, NC and compare the amenities they offer before buying a bus ticket.
A trip to Charlotte, NC from St. Louis, MO is worth doing but not as a day trip with a journey time of 17h 30m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from St. Louis, MO to Charlotte, NC is July.
It's helpful to compare your options as there are 3 ways to travel between St. Louis, MO and Charlotte, NC including taking a train, bus, and flight.
Yes, the following accessibility options are available when taking the bus from St. Louis, MO to Charlotte, NC:
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from St. Louis, MO to Charlotte, NC for bus company Greyhound.
Some of the most interesting sights to explore in Charlotte, NC are:
  • NASCAR Hall of Fame, an interactive museum dedicated to the history and heritage of NASCAR with exhibits and simulators
  • Discovery Place Science, a hands-on science and technology museum featuring interactive exhibits and an IMAX theater
  • Freedom Park, a 98-acre park offering walking trails, sports fields, and a picturesque lake
  • Mint Museum Uptown, an art museum showcasing American, contemporary, and European art collections
  • Levine Museum of the New South, focusing on post-Civil War Southern history and culture.
The best things to do in Charlotte, NC include:
  • Carowinds, a large amusement park featuring roller coasters and a water park
  • U.S. National Whitewater Center, offering outdoor activities like whitewater rafting, kayaking, and rock climbing
  • NoDa, Charlotte's historic arts and entertainment district with galleries, music venues, and unique dining experiences
  • Charlotte Motor Speedway, hosting NASCAR races and other motorsport events
  • Billy Graham Library, a museum and library dedicated to the life and legacy of the famous evangelist.
Whether you can cancel your bus ticket from St. Louis, MO to Charlotte, NC depends on the bus companies:
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from St. Louis, MO to Charlotte, NC.
Yes, the following luggage options are included when booking a bus ticket from St. Louis, MO to Charlotte, NC:
  • Greyhound
    • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from St. Louis, MO to Charlotte, NC:
  • Greyhound
    • $15 per additional bag.
Unfortunately, pets are not allowed on the bus from St. Louis, MO to Charlotte, NC.
You can reserve your seat on the bus from St. Louis, MO to Charlotte, NC with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from St. Louis, MO to Charlotte, NC with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from St. Louis, MO to Charlotte, NC with the following bus company: Greyhound.

popular bus stations

Popular bus stations from St. Louis, MO to Charlotte, NC

St. Louis
Charlotte
The major bus station for departures in St. Louis is St. Louis, S 15th St (Civic center). Find all the information you need to know about services, amenities and connections at St. Louis, S 15th St (Civic center) for your trip from St. Louis to Charlotte.
St. Louis, S 15th St (Civic center)
information
HomeBusesBuses in USABus tickets to Charlotte, NCSt. Louis, MO to Charlotte, NC bus

The Omio App Makes Travel Planning Easy

We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.

ios-badge
android-badge
Hand With Phone