- Must visit
Birmingham Museum of Art
Major regional museum with strong American, Asian, African, and contemporary collections plus an excellent sculpture garden.
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The cheapest and fastest buses from St. Louis, MO to Birmingham, AL
Showing times, prices and bookable tickets for Sep 19
Cheapest price on Sep 19
CHF55
Average ticket price on Sep 19
CHF56
Fastest journey on Sep 19
9 h 55 m
Average journey duration on Sep 19
11 h 40 m
Buses on Sep 19
3
Distance
645 km
Cheap tickets
The best way to find a cheap bus ticket from St. Louis, MO to Birmingham, AL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from St. Louis, MO to Birmingham, AL will cost around CHF56 if you buy it on the day, but the cheapest tickets can be found for only CHF55.
Fast buses
It's difficult to get from St. Louis, MO to Birmingham, AL without transferring at least once.
· 1:00 AM12h25St. Louis, S 15th St (Civic center)1:25 PMBirmingham Jefferson County Transit AuthorityCHF551One-way1 transfer
FlixBus+4:00 PM9h55St. Louis, S 15th St (Civic center)1:55 AMBirmingham Jefferson County Transit AuthorityCHF561One-way1 transfer- FlixBus+11:45 PM12h40St. Louis, S 15th St (Civic center)12:25 PMBirmingham Jefferson County Transit AuthorityCHF561One-way1 transfer
- FlixBus+4:00 PM9h55St. Louis, S 15th St (Civic center)1:55 AMBirmingham Jefferson County Transit AuthorityCHF561One-way1 transfer
- · 1:00 AM12h25St. Louis, S 15th St (Civic center)1:25 PMBirmingham Jefferson County Transit AuthorityCHF551One-way1 transfer
- FlixBus+11:45 PM12h40St. Louis, S 15th St (Civic center)12:25 PMBirmingham Jefferson County Transit AuthorityCHF561One-way1 transfer
Travel Information
Compare bus, train, and flight for St. Louis, MO to Birmingham, AL
Omio recommends booking the flight as it is the most popular option from St. Louis, MO to Birmingham, AL among Omio's users. If you are prioritising price, take the bus, with an average ticket price of CHF75 For those with little time, consider booking a flight, which has an average total journey time of 5h 56m. Average ticket prices depend on the travel mode: a bus costs an average of CHF75, while a train costs an average of CHF1186.
Distance: 400 miles (645 km)
Compare bus with
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
CHF75 Average price Cheapest | CHF415 Average price | CHF1186 Average price | CHF82 Average price (fuel + tolls) |
9h 56m Average total duration 9h 26m Onboard + 30m Additional time* | 5h 56m Average total duration Fastest 3h 56m Onboard + 2h 0m Additional time* | 43h 42m Average total duration 43h 12m Onboard + 30m Additional time* | 7h 25m Average total duration (door-to-door) |
Most popular bus company |  Most popular airline |  Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
The cheapest way to travel from St. Louis, MO to Birmingham, AL is a bus with an average price of CHF75.
This is compared to other travel options from St. Louis, MO to Birmingham, AL:
A bus is CHF340 less than a flight for this route with tickets for a flight from St. Louis, MO to Birmingham, AL costing on average CHF415.
A bus is CHF1111 less than a train for this route with tickets for a train from St. Louis, MO to Birmingham, AL costing on average CHF1186.
The fastest way to travel from St. Louis, MO to Birmingham, AL is by flight with an average journey time of 3h 56m.
Other travel options to Birmingham, AL take longer:
Bus takes on average 9h 26m.
Train takes on average 43h 12m.
It's helpful to compare your options as there are 3 ways to travel between St. Louis, MO and Birmingham, AL including taking a bus, train, and flight.
We recommend using the flight as it is the most popular way to get from St. Louis, MO to Birmingham, AL among Omio's users.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.
Tickets start at around CHF75 compared to roughly CHF82 in fuel and tolls — a saving of about CHF6. The journey takes 9h 26m versus 7h 25m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
St. Louis, MO to Birmingham, AL Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 01:00AM | Arrival Time 01:25PM | Duration 12h25 | Departure days Everyday | Cheapest price CHF45 |
Operator FlixBus | Departure Time 04:00PM | Arrival Time 01:55AM | Duration 9h55 | Departure days Everyday | Cheapest price CHF46 |
Operator FlixBus | Departure Time 11:45PM | Arrival Time 12:25PM | Duration 12h40 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price CHF47 |
Live departures
St. Louis, MO to Birmingham, AL bus times
The table below shows live departures for St. Louis, MO to Birmingham, AL buses for today, Friday, September 18. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| · | 1:00 AM St. Louis, S 15th St (Civic center) | 12h25 | 1:25 PM Birmingham Jefferson County Transit Authority | 1 transfer | |
| FlixBus+ | 4:00 PM St. Louis, S 15th St (Civic center) | 9h55 | 1:55 AM Birmingham Jefferson County Transit Authority | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets St. Louis, MO to Birmingham, AL by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book St. Louis, MO to Birmingham, AL buses with Omio?
Greyhound as well as FlixBus offer buses services from St. Louis, MO to Birmingham, AL.
Omio is an official ticket reseller for all your travel options from St. Louis, MO to Birmingham, AL.
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of FlixBus to find the best option for your trip from St. Louis, MO to Birmingham, AL.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from St. Louis, MO to Birmingham, AL.
Why book with Omio over Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus to find the best option for your trip from St. Louis, MO to Birmingham, AL.
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from St. Louis, MO to Birmingham, AL.
Journey information
Overview: Bus from St. Louis, MO to Birmingham, AL
USAUSA
Buses from St. Louis, MO to Birmingham, AL run on average 3 times per day, taking around 9h 26m. Cheap bus tickets for this journey start at CHF51 if you book in advance.
The earliest bus runs at 01:00, the last at 23:35. The fastest bus covers the 400 miles (645 km) distance in 9h 0m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 400 miles (645 km) |
Average bus duration 9h 26m |
Cheapest ticket price CHF51 |
Buses per day 3 |
Fastest bus 9h 0m |
First bus 1:00 AM |
Last bus 11:35 PM |
Cheapest Month Aug |
Cheapest Day Sat |
High Season Jul - Sep |
Low Season Jan - Mar |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: FlixBus, Greyhound from St. Louis, MO to Birmingham, ALYou can travel by bus between St. Louis, MO to Birmingham, AL with FlixBus, Greyhound for as low as CHF51. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
9h 0m
Cheapest FlixBus Price
CHF51
FlixBus frequency
2 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
9h 55m
Cheapest Greyhound Price
CHF51
Greyhound frequency
1 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Complete guide to Birmingham, AL
Things to do in Birmingham, AL
Discover the best of Birmingham, AL — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Birmingham, AL trip today.
- Must visit
Birmingham Civil Rights Institute
Powerful civil rights museum with immersive exhibits that explain Birmingham’s central role in the struggle for equality.
- Recommended
McWane Science Center
Hands-on museum blending science, technology, and regional history, popular with families and curious adults alike.
- Must visit
Railroad Park
Large urban green space with lawns, trails, and a prized skyline view from the hilltop near Vulcan.
- Recommended
Lakeview District
Lively downtown entertainment district with bars, murals, music venues, and easy access to theaters and sports.
- Recommended
Avondale
Trendy neighborhood of shops, coffee spots, nightlife, and colorful streets that showcase Birmingham’s creative energy.
- Gluten-free
Alabama White Sauce Barbecue Chicken
Alabama white sauce barbecue chicken is smoked chicken dressed with a tangy mayo-based sauce, a North Alabama staple that defines the region’s barbecue identity.
- Gluten-free
Pulled Pork Barbecue
Pulled pork barbecue is slow-smoked and served chopped or shredded, often with sauce and sides. It is a classic Birmingham and Alabama comfort food.
- Vegetarian
Fried Green Tomatoes
Fried green tomatoes are unripe tomatoes sliced, breaded, and fried. They are a beloved Southern starter tied closely to Alabama home cooking.
Highlands Bar and Grill
Refined Southern fine dining destination known for elegant tasting menus, local ingredients, and polished service in an upscale atmosphere.
Niki's West
Long-running meat-and-three favorite serving fried chicken, vegetables, and pies in a classic cafeteria-style Southern setting.
Helen
Acclaimed modern restaurant with wood-fired cooking, seasonal Southern dishes, and a stylish but relaxed neighborhood atmosphere.
United States dollar ($)
Moderate for U.S. city travel. Hotels are often cheaper than major metros, while dining and rideshares are typical; transit use is limited for most visitors.
Average meal costs
- Budget
- $10-15 for fast food or a casual meal.
- Mid-range
- $20-35 per person for a restaurant meal.
- Fine dining
- $60+ per person for upscale dining.
- Coffee
- $3-5 for coffee or a cappuccino.
Tipping culture
Tip 18-20% at restaurants, more for excellent service. Taxis usually get 10-15%. For cafes, round up or leave $1-2 on larger orders.
FAQs: Bus from St. Louis, MO to Birmingham, AL
Find answers to the most common questions about traveling from St. Louis, MO to Birmingham, AL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Birmingham, AL, this guide helps you travel smarter and with confidence.
Cheap bus tickets from St. Louis, MO to Birmingham, AL can start from as little as CHF51 when you book in advance. The average bus ticket price for St. Louis, MO to Birmingham, AL is CHF75 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from St. Louis, MO to Birmingham, AL is 9h 0m to travel the 400 miles (645 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from St. Louis, MO to Birmingham, AL leaves at 1:00 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from St. Louis, MO to Birmingham, AL leaves at 11:35 PM.
There are 3 buses a day from St. Louis, MO to Birmingham, AL which require at least one change with Greyhound, FlixBus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from St. Louis, MO to Birmingham, AL, you can count on Greyhound, FlixBus for the best way to get you to Birmingham, AL. You can also check all possible bus companies who offer a service between St. Louis, MO and Birmingham, AL and compare the amenities they offer before buying a bus ticket.
Passengers board the bus most frequently from St. Louis, S 15th St (Civic center), which is located around away from the city centre, and they get off the bus at Birmingham Jefferson County Transit Authority, located 1 away from the city centre.
A trip to Birmingham, AL from St. Louis, MO is worth doing but not as a day trip with a journey time of 9h 0m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from St. Louis, MO to Birmingham, AL is August.
It's helpful to compare your options as there are 3 ways to travel between St. Louis, MO and Birmingham, AL including taking a bus, train, and flight.
Yes, there are bathrooms on board the bus from St. Louis, MO to Birmingham, AL for bus company Greyhound, FlixBus.
Yes, the following accessibility options are available when taking the bus from St. Louis, MO to Birmingham, AL:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Whether you can cancel your bus ticket from St. Louis, MO to Birmingham, AL depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company Greyhound, FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from St. Louis, MO to Birmingham, AL.
Yes, the following luggage options are included when booking a bus ticket from St. Louis, MO to Birmingham, AL:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from St. Louis, MO to Birmingham, AL:
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from St. Louis, MO to Birmingham, AL. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from St. Louis, MO to Birmingham, AL with the following bus company: Greyhound, FlixBus
Yes, there are USB plugs on board the bus from St. Louis, MO to Birmingham, AL with the following bus company: Greyhound, FlixBus.
Yes, there is Wifi on board the bus from St. Louis, MO to Birmingham, AL with the following bus company: Greyhound, FlixBus.
Since neither St. Louis, MO nor Birmingham, AL are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the train as it is the most popular way to get from St. Louis, MO to Birmingham, AL among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Birmingham, AL, travelers should be cautious of pickpocketing and vehicle break-ins, especially in crowded areas and parking lots. Avoid poorly lit or unfamiliar neighborhoods after dark. Common scams include overcharging by unofficial taxi or ride-share drivers and distraction techniques used to steal wallets or phones. Staying alert and using reputable transportation services helps ensure safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from St. Louis, MO to Birmingham, AL
Most St. Louis, MO to Birmingham, AL buses use the St. Louis, S 15th St (Civic center) to Birmingham Jefferson County Transit Authority station pair. Use this guide to compare St. Louis, MO and Birmingham, AL bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in St. Louis
Arrival bus stations in Birmingham
Which St. Louis, MO station do buses to Birmingham, AL leave from?
Buses from St. Louis, MO to Birmingham, AL leave from St. Louis, S 15th St (Civic center). The station is 0 miles (1 km) from St. Louis, MO city centre at S 15th St, St. Louis, MO, USA.
St. Louis, S 15th St (Civic center)S 15th St, St. Louis, MO, USA
City-centre transport
Getting to St. Louis, S 15th St (Civic center) from St. Louis city centre
TrainMlb, Mlr · 4m · CHF3 · every ~14 min
Bus19, 32, 40 · 8m · CHF1 · every ~9 min
St. Louis, S 15th St (Civic center) bus station facilities and services
St. Louis, S 15th St (Civic center) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at St. Louis, S 15th St (Civic center). ATMs are available at St. Louis, S 15th St (Civic center).
Tickets and information
Ticket office support is available at St. Louis, S 15th St (Civic center).
Parking, taxis and toilets
Available at St. Louis, S 15th St (Civic center): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at St. Louis, S 15th St (Civic center): Wheelchair accessible routes available.
Which Birmingham, AL station do buses from St. Louis, MO arrive at?
Buses from St. Louis, MO to Birmingham, AL arrive at Birmingham Jefferson County Transit Authority. Birmingham Jefferson County Transit Authority is 0 miles (1 km) from Birmingham, AL city centre.
Birmingham Jefferson County Transit Authority1801 Morris Ave, Birmingham, AL 35203, USA
City-centre transport
Getting to Birmingham Jefferson County Transit Authority from Birmingham city centre
Birmingham Jefferson County Transit Authority is 1 km from Birmingham city centre. Public transport options include:
Bus22, 23 · 7m · CHF1 · every ~2 min
Birmingham Jefferson County Transit Authority bus station facilities and services
Birmingham Jefferson County Transit Authority has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Birmingham Jefferson County Transit Authority. ATMs are available at Birmingham Jefferson County Transit Authority.
Tickets and information
Ticket office support is available at Birmingham Jefferson County Transit Authority.
Parking, taxis and toilets
Available at Birmingham Jefferson County Transit Authority: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Birmingham Jefferson County Transit Authority: Facility is accessible to individuals with disabilities.
Most popular bus connections from St. Louis, MO
More options for your journey from St. Louis, MO to Birmingham, AL
Here are some other resources that might have the information you need
Most popular buses to and from Birmingham, AL and St. Louis, MO
Most popular bus connections to Birmingham, AL
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