- Must visit
Arizona-Sonora Desert Museum
A renowned desert museum combining zoo, botanical garden, art, and natural history exhibits focused on the Sonoran Desert. It is one of Tucson’s signature attractions and highly regarded for immersive
Cheapest price
$293
Average price
$293
Fastest journey
1 d 10 h 20 m
Average duration
1 d 10 h 20 m
Buses per day
1
Distance
2003 km
The best way to find a cheap bus ticket from St. Louis, MO to Tucson, AZ is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from St. Louis, MO to Tucson, AZ will cost around $293 if you buy it on the day, but the cheapest tickets can be found for only $293.
Of the 1 buses that leave St. Louis, MO for Tucson, AZ on Sat, Jul 11, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Jul 11 the direct buses cover the 2003 km distance in an average of 1 d 10 h 20 m but if you time it right, some buses will get you there in just 1 d 10 h 20 m .
On Sat, Jul 11 the slowest buses will take 1 d 10 h 20 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Omio recommends booking the bus as it is the most popular option from St. Louis, MO to Tucson, AZ among Omio's users. If you are prioritising price take the bus with prices starting from $142. For those with little time consider booking a flight which can get you there in 4h 22m. The ticket price range depends on the travel mode: a bus costs an average of $142, and a flight costs an average of $263.
Distance: 1244 miles (2003 km)
Most popular Bus | Train | Flight | Driving |
|---|---|---|---|
$270 Average price Cheapest | $371 Average price | $481 Average price | $286 Average price (fuel + tolls) |
33h 34m Average total duration 33h 4m Onboard + 30m Additional time* | 47h 27m Average total duration 46h 57m Onboard + 30m Additional time* | 7h 22m Average total duration Fastest 4h 22m Onboard + 3h 0m Additional time* | 21h 15m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from St. Louis, MO to Tucson, AZ:
A bus is $102 (€84) less than a train for this route with tickets for a train from St. Louis, MO to Tucson, AZ costing on average $371 (€305).
A bus is $211 (€174) less than a flight for this route with tickets for a flight from St. Louis, MO to Tucson, AZ costing on average $481 (€395).
Other travel options to Tucson, AZ take longer:
Bus takes on average 33h 4m.
Train takes on average 46h 57m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 06:30AM | Arrival Time 06:30PM | Duration 36h00 | Departure days Thu | Cheapest price $343 |
Operator Greyhound | Departure Time 07:20AM | Arrival Time 05:40PM | Duration 34h20 | Departure days Sat | Cheapest price $293 |
Operator Greyhound USA | Departure Time 08:40AM | Arrival Time 07:10PM | Duration 34h30 | Departure days Sun | Cheapest price $426 |
Operator Greyhound | Departure Time 02:10PM | Arrival Time 12:35AM | Duration 34h25 | Departure days Tue, Wed | Cheapest price $200 |
Operator Greyhound | Departure Time 03:10PM | Arrival Time 04:20AM | Duration 61h10 | Departure days Tue | Cheapest price $342 |
Operator Greyhound | Departure Time 09:30PM | Arrival Time 01:50PM | Duration 40h20 | Departure days Mon | Cheapest price $278 |
The table below shows live departures for St. Louis, MO to Tucson, AZ buses for tomorrow, Saturday, July 11. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 7:20 AM St. Louis, MO | 34h20 | 5:40 PM Tucson, AZ | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from St. Louis, MO to Tucson, AZ run on average 7 times per day, taking around 33h 4m. Cheap bus tickets for this journey start at $142 (€117) if you book in advance.
The earliest bus runs at 01:35, the last at 21:25. The fastest bus covers the 1244 miles (2003 km) distance in 34h 20m.
Distance 1244 miles (2003 km) |
Average bus duration 33h 4m |
Cheapest ticket price $142 (€117) |
Buses per day 7 |
Fastest bus 34h 20m |
First bus 1:35 AM |
Last bus 9:25 PM |
Cheapest Month Dec |
Cheapest Day Fri |
High Season Oct - Dec |
Low Season Jul - Sep |
Discover the best of Tucson — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Tucson trip today.
A renowned desert museum combining zoo, botanical garden, art, and natural history exhibits focused on the Sonoran Desert. It is one of Tucson’s signature attractions and highly regarded for immersive
A major downtown art museum with American, Latin American, Indigenous, and contemporary collections. It is a strong cultural stop in the historic core and often recommended for first-time visitors.
A contemporary art museum in a converted fire station, featuring rotating exhibitions and regional artists. It is popular with visitors looking for a modern and more local creative perspective.
A spectacular desert landscape filled with giant saguaro cacti, scenic drives, and classic Sonoran views. It is one of the top outdoor experiences near Tucson and especially popular at sunset.
A scenic canyon area known for desert walks, mountain views, and seasonal water crossings. It is a favorite for active visitors and one of Tucson’s most photographed natural areas.
A dramatic mountain road climbing from desert to pine forest, with major changes in scenery and temperature. It is one of the region’s signature drives and highly popular with locals and visitors.
A bacon-wrapped hot dog in a bolillo-style bun, typically topped with beans, onion, tomato, mustard, mayo, and jalapeno sauce. It is one of Tucson's signature borderlands street foods.
Air-dried beef, often shredded and cooked with eggs, chiles, or vegetables. It is a classic Sonoran specialty strongly associated with Tucson's Mexican culinary heritage.
An open-faced flour tortilla baked until crisp and topped with melted cheese, often finished with green chiles. It is a long-standing Tucson and Arizona favorite.
Well-known downtown restaurant celebrated for refined Mexican cuisine, elegant presentation, and a distinctive menu-driven dining experience.
A popular gastropub blending Southern and Southwestern flavors, known for creative comfort food and a stylish but relaxed atmosphere.
Casual favorite for inventive tacos, salsas, and tequila in a colorful, energetic setting that remains popular with locals and visitors.
Generally cheaper than major U.S. tourist cities. Hotels vary by season, while dining and transport are usually manageable.
Tip 15-20% at restaurants; 20% for strong service. Tip USD 1-2 per drink at bars, round up taxis, and tip hotel staff USD 2-5.
Find answers to the most common questions about traveling from St. Louis, MO to Tucson, AZ by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Tucson, AZ, this guide helps you travel smarter and with confidence.

Most St. Louis, MO to Tucson, AZ buses use the St. Louis, S 15th St (Civic center) to Tucson, E 12th St (Bus Station) station pair, with some services arriving at Tuscon, University of Arizona Transportation Office. Use this guide to compare St. Louis, MO and Tucson, AZ bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need