- Must visit
Arizona-Sonora Desert Museum
A renowned desert museum combining zoological, botanical, and natural history exhibits focused on the Sonoran Desert. One of Tucson’s signature attractions and highly worthwhile for first-time visits.
Cheapest price
$128
Average price
$135
Fastest journey
1 d 10 h 20 m
Average duration
1 d 12 h 17 m
Buses per day
10
Distance
2003 km
The best way to find a cheap bus ticket from St. Louis, MO to Tucson, AZ is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from St. Louis, MO to Tucson, AZ will cost around $135 if you buy it on the day, but the cheapest tickets can be found for only $128.
It's difficult to get from St. Louis, MO to Tucson, AZ without transferring at least once.
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· · · Omio recommends booking the bus as it is the most popular option from St. Louis, MO to Tucson, AZ among Omio's users. If you are prioritising price take the bus with prices starting from $145. For those with little time consider booking a flight which can get you there in 4h 22m. The ticket price range depends on the travel mode: a bus costs an average of $145, and a flight costs an average of $269.
Distance: 1244 miles (2003 km)
Most popular Bus | Train | Flight | Driving |
|---|---|---|---|
$275 Average price Cheapest | $379 Average price | $490 Average price | $291 Average price (fuel + tolls) |
33h 34m Average total duration 33h 4m Onboard + 30m Additional time* | 47h 27m Average total duration 46h 57m Onboard + 30m Additional time* | 7h 22m Average total duration Fastest 4h 22m Onboard + 3h 0m Additional time* | 21h 15m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from St. Louis, MO to Tucson, AZ:
A bus is $104 (€84) less than a train for this route with tickets for a train from St. Louis, MO to Tucson, AZ costing on average $379 (€305).
A bus is $215 (€174) less than a flight for this route with tickets for a flight from St. Louis, MO to Tucson, AZ costing on average $490 (€395).
Other travel options to Tucson, AZ take longer:
Bus takes on average 33h 4m.
Train takes on average 46h 57m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 01:20AM | Arrival Time 09:40AM | Duration 34h20 | Departure days Wed | Cheapest price $138 |
Operator Greyhound | Departure Time 06:30AM | Arrival Time 06:30PM | Duration 36h00 | Departure days Thu | Cheapest price $350 |
Operator Greyhound | Departure Time 07:20AM | Arrival Time 05:40PM | Duration 34h20 | Departure days Sat | Cheapest price $299 |
Operator Greyhound USA | Departure Time 08:40AM | Arrival Time 07:10PM | Duration 34h30 | Departure days Wed, Sun | Cheapest price $133 |
Operator Greyhound | Departure Time 09:10AM | Arrival Time 10:00PM | Duration 62h50 | Departure days Wed | Cheapest price $133 |
Operator Greyhound | Departure Time 02:10PM | Arrival Time 12:35AM | Duration 34h25 | Departure days Tue | Cheapest price $296 |
Operator Greyhound | Departure Time 03:10PM | Arrival Time 04:20AM | Duration 61h10 | Departure days Tue | Cheapest price $348 |
Operator Greyhound | Departure Time 04:30PM | Arrival Time 06:50AM | Duration 40h20 | Departure days Wed | Cheapest price $137 |
Operator Greyhound | Departure Time 09:30PM | Arrival Time 01:50PM | Duration 40h20 | Departure days Mon | Cheapest price $284 |
Operator Greyhound | Departure Time 11:59PM | Arrival Time 07:10PM | Duration 45h11 | Departure days Wed | Cheapest price $128 |
The table below shows live departures for St. Louis, MO to Tucson, AZ buses for today, Tuesday, May 26. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 2:10 PM St. Louis, MO | 34h25 | 12:35 AM Tucson, AZ | 0 transfersDirect | |
![]() | 3:10 PM St. Louis, MO | 61h10 | 4:20 AM Tucson, AZ | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from St. Louis, MO to Tucson, AZ run on average 7 times per day, taking around 33h 4m. Cheap bus tickets for this journey start at $145 (€117) if you book in advance.
The earliest bus runs at 01:35, the last at 21:25. The fastest bus covers the 1244 miles (2003 km) distance in 34h 20m.
Distance 1244 miles (2003 km) |
Average bus duration 33h 4m |
Cheapest ticket price $145 (€117) |
Buses per day 7 |
Fastest bus 34h 20m |
First bus 1:35 AM |
Last bus 9:25 PM |
Cheapest Month Dec |
Cheapest Day Fri |
High Season Oct - Dec |
Low Season Jul - Sep |
Discover the best of Tucson — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Tucson trip today.
A renowned desert museum combining zoological, botanical, and natural history exhibits focused on the Sonoran Desert. One of Tucson’s signature attractions and highly worthwhile for first-time visits.
Downtown art museum with American, Latin American, modern, and contemporary collections in a historic block. A strong choice for art lovers exploring central Tucson.
A distinctive museum dedicated to miniatures and finely crafted room settings. Popular with families and visitors seeking something unusual and memorable.
Desert landscape filled with giant saguaro cacti, scenic drives, hiking trails, and classic Sonoran views. One of the essential outdoor experiences around Tucson.
The western district of the national park, known for dense cactus forests and excellent sunset scenery. Highly photogenic and especially popular with first-time visitors.
A scenic desert canyon with paved tram road, hiking trails, and mountain views in the Santa Catalina foothills. A top outdoor destination for Tucson visitors.
A bacon-wrapped hot dog tucked into a soft bolillo roll and loaded with beans, onions, tomatoes, mayo, mustard, and jalapeo sauce. It is one of Tucsons signature borderlands street foods.
Thinly sliced beef dried in the desert style, then shredded and often cooked with eggs, chiles, or tomatoes. It is a hallmark of Sonoran cuisine in Tucson.
An open-faced flour tortilla baked until crisp and topped with melted cheese, sometimes with green chiles. This Arizona classic is especially associated with Tucson family restaurants.
Upscale dining with desert views, strong wine service, and refined Southwestern cuisine. A good choice for a fine-dining Tucson meal.
Well-known downtown restaurant celebrated for polished Mexican cooking, seasonal menus, and colorful presentation in an intimate setting.
Popular modern taco spot with creative fillings, salsas, and a lively casual atmosphere. It is a dependable choice for contemporary Tucson flavors.
Moderate by U.S. standards. Casual dining and coffee are reasonable, while hotels and upscale dining cost more in peak season.
Tip 18-20% in restaurants; 20%+ for great service. Tip bartenders USD 1-2 per drink, taxi/rideshare 10-15%, hotel staff USD 2-5, and round up for cafes.
Find answers to the most common questions about traveling from St. Louis, MO to Tucson, AZ by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Tucson, AZ, this guide helps you travel smarter and with confidence.

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