- Recommended
History Center of San Luis Obispo County
Regional history museum in a restored Carnegie Library with exhibits on Indigenous communities, ranching, rail, and town life.
Buses from Las Vegas, NV to San Luis Obispo, CA run on average 2 times per day, taking around 9h 55m. Cheap bus tickets for this journey start at $46 if you book in advance.
The earliest bus runs at 00:15, the last at 23:45. The fastest bus covers the 315 miles (508 km) distance in 9h 5m.
Plan this route
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Las Vegas, NV to San Luis Obispo, CA.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:25AM | Arrival Time 10:35PM | Duration 22h10 | Departure days Fri | Cheapest price $254 |
Operator Greyhound | Departure Time 02:30AM | Arrival Time 01:00PM | Duration 10h30 | Departure days Mon, Sun | Cheapest price $50 |
Operator Flixbus USA | Departure Time 06:40AM | Arrival Time 01:25PM | Duration 30h45 | Departure days Sat | Cheapest price $79 |
Operator Greyhound | Departure Time 11:45PM | Arrival Time 01:00PM | Duration 13h15 | Departure days Mon, Sun | Cheapest price $51 |
Buses from Las Vegas, NV to San Luis Obispo, CA with Greyhound. Overnight buses available on this route with Greyhound. Use the details below to compare onboard facilities.
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of San Luis Obispo, CA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect San Luis Obispo, CA trip today.
Regional history museum in a restored Carnegie Library with exhibits on Indigenous communities, ranching, rail, and town life.
Rail museum by the station with model layouts, restored equipment, and hands-on displays for families and train enthusiasts.
Children’s museum downtown with interactive science, art, and play exhibits designed for younger visitors and family outings.
Downtown creekside park with lawns, paths, public art, and regular community events in the center of the city.
Popular local peak with a short but steep trail, broad city views, and sunset scenery close to downtown.
Compact downtown district with shops, historic facades, galleries, and walkable streets linking major sights and events.
Tri-tip barbecue is Central Coast's signature beef cut, oak-grilled and sliced. It is a regional staple tied to Santa Maria-style cookouts nearby.
Santa Maria-style beans are pink beans simmered with bacon, ham, and spices. They commonly accompany local barbecue across the Central Coast.
Abalone is a historic Central Coast seafood, often pan-fried or breaded. It reflects the area's coastal harvest traditions and old California cuisine.
Long-running seafood house near downtown with oysters, chowder, and fish dishes. Relaxed classic atmosphere focused on fresh coastal fare.
Lively downtown grill known for oak-fired tri-tip, steaks, and seafood. Casual, historic setting and a classic place to try Central Coast barbecue.
Refined downtown restaurant serving contemporary Californian dishes and cocktails. Stylish atmosphere suited to a more upscale dinner.
Moderate for California. Hotels and dining cost more than smaller inland towns, but transit and casual meals are manageable for most visitors.
Tip 18-20% at restaurants, $1-2 per drink at bars, and round up or tip 10-15% for taxis. Cafes often have tip jars or screens.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in San Luis Obispo, CA.
Find answers to the most common questions about traveling from Las Vegas, NV to San Luis Obispo, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Luis Obispo, CA, this guide helps you travel smarter and with confidence.

Most Las Vegas, NV to San Luis Obispo, CA buses use the Las Vegas, Lv All In Shuttle LLC to San Luis Obispo, Santa Barbara Ave / High St (San Luis Obispo Railroad Museum) station pair. Use this guide to compare Las Vegas, NV and San Luis Obispo, CA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Las Vegas, Lv All In Shuttle LLC is 11 km from Las Vegas city centre. Public transport options include:
Las Vegas, Lv All In Shuttle LLC has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Several fast food outlets are nearby.
Wi-Fi is available at Las Vegas, Lv All In Shuttle LLC. ATMs are aTMs are available in nearby locations.
Ticket office support is available at Las Vegas, Lv All In Shuttle LLC.
Available at Las Vegas, Lv All In Shuttle LLC: Parking, Taxis, WC.
Accessibility facilities are available at Las Vegas, Lv All In Shuttle LLC: Wheelchair ramps are available for accessibility.
Las Vegas, S Las Vegas Blvd (Forever 21) is 5 km from Las Vegas city centre. Public transport options include:
Las Vegas, S Las Vegas Blvd (Forever 21) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Nearby restaurants on S Las Vegas Blvd.
Wi-Fi is available at Las Vegas, S Las Vegas Blvd (Forever 21). ATMs are available nearby on S Las Vegas Blvd.
Ticket office support is available at Las Vegas, S Las Vegas Blvd (Forever 21).
Available at Las Vegas, S Las Vegas Blvd (Forever 21): Parking, Taxis, WC.
Accessibility facilities are available at Las Vegas, S Las Vegas Blvd (Forever 21): Accessible for passengers with disabilities.
Las Vegas, 1st St (Downtown) is 1 km from Las Vegas city centre. Public transport options include:
Las Vegas, 1st St (Downtown) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Fast food restaurants nearby
Free Wi-Fi in waiting area. ATMs are aTM located inside.
Ticket office support is available at Las Vegas, 1st St (Downtown).
Available at Las Vegas, 1st St (Downtown): Parking, Taxis, WC.
Accessibility facilities are available at Las Vegas, 1st St (Downtown): Wheelchair accessible.
San Luis Obispo, Santa Barbara Ave / High St (San Luis Obispo Railroad Museum) is 1 km from San Luis Obispo city centre. Public transport options include:
San Luis Obispo, Santa Barbara Ave / High St (San Luis Obispo Railroad Museum) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at San Luis Obispo, Santa Barbara Ave / High St (San Luis Obispo Railroad Museum). ATMs are available at San Luis Obispo, Santa Barbara Ave / High St (San Luis Obispo Railroad Museum).
Ticket office support is available at San Luis Obispo, Santa Barbara Ave / High St (San Luis Obispo Railroad Museum).
Available at San Luis Obispo, Santa Barbara Ave / High St (San Luis Obispo Railroad Museum): Parking, Taxis, WC.
Accessibility facilities are available at San Luis Obispo, Santa Barbara Ave / High St (San Luis Obispo Railroad Museum): Basic accessibility features available.
Check bus stations information for Las Vegas, NV and San Luis Obispo, CA, including where buses depart and arrive on this route.