Travel Information
Compare bus and flight for Indianapolis, IN to San Luis Obispo, CA
Omio recommends booking the flight as it is the most popular option from Indianapolis, IN to San Luis Obispo, CA among Omio's users. If you are prioritising price take the bus with prices starting from $241. For those with little time consider booking a flight which can get you there in 7h 40m. The ticket price range depends on the travel mode: a bus costs an average of $241, and a flight costs an average of $500.
Distance: 1903 miles (3064 km)
Compare bus with
| Bus | Most popular Flight | Driving |
|---|---|---|
$241 Average price Cheapest | $500 Average price | $441 Average price (fuel + tolls) |
68h 45m Average total duration 68h 15m Onboard + 30m Additional time* | 10h 40m Average total duration Fastest 7h 40m Onboard + 3h 0m Additional time* | 32h 29m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Indianapolis, IN to San Luis Obispo, CA:
A bus is $260 (€213) less than a flight for this route with tickets for a flight from Indianapolis, IN to San Luis Obispo, CA costing on average $500 (€409).
Other travel options to San Luis Obispo, CA take longer:
Bus takes on average 68h 15m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Indianapolis, IN to San Luis Obispo, CA Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 01:10AM | Arrival Time 09:25PM | Duration 68h15 | Departure days Fri | Cheapest price $241 |
Operator Greyhound USA | Departure Time 05:00AM | Arrival Time 01:25PM | Duration 56h25 | Departure days Fri, Sat | Cheapest price $606 |
Compare prices and tickets Indianapolis, IN to San Luis Obispo, CA by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Indianapolis, IN to San Luis Obispo, CA buses with Omio?
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Indianapolis, IN to San Luis Obispo, CA.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Indianapolis, IN to San Luis Obispo, CA.
Journey information
Overview: Bus from Indianapolis, IN to San Luis Obispo, CA
Buses from Indianapolis, IN to San Luis Obispo, CA run on average 3 times per day, taking around 68h 15m. Cheap bus tickets for this journey start at $241 (€197) if you book in advance.
The earliest bus runs at 09:30, the last at 23:30. The fastest bus covers the 1903 miles (3064 km) distance in 68h 15m.
Distance 1903 miles (3064 km) |
Average bus duration 68h 15m |
Cheapest ticket price $241 (€197) |
Buses per day 3 |
Fastest bus 68h 15m |
First bus 9:30 AM |
Last bus 11:30 PM |
Cheapest Month Feb |
Cheapest Day Thu |
High Season Oct - Dec |
Low Season Jan - Mar |
Bus providers: Greyhound from Indianapolis, IN to San Luis Obispo, CAYou can travel by bus between Indianapolis, IN to San Luis Obispo, CA with Greyhound for as low as $241 (€197). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from Indianapolis, IN to San Luis Obispo, CA
Find answers to the most common questions about traveling from Indianapolis, IN to San Luis Obispo, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Luis Obispo, CA, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Bubblegum Alley, a narrow alleyway famous for its walls covered in layers of chewed gum left by visitors
- Mission San Luis Obispo de Tolosa, a historic Spanish mission founded in 1772 with a museum and beautiful gardens
- Bishop Peak, a popular hiking destination offering panoramic views of the city and surrounding landscapes
- San Luis Obispo Museum of Art, a contemporary art museum showcasing works by regional and national artists
- Avila Beach, a nearby coastal spot known for its sandy shores and scenic pier.
- Stroll through Downtown SLO, a vibrant area with shops, restaurants, and the famous Thursday Night Farmers' Market
- Attend a performance at the Fremont Theater, a historic venue known for its art deco architecture and live events
- Visit the San Luis Obispo Children's Museum, offering interactive exhibits and activities for kids
- Explore the local wineries and vineyards, enjoying tastings and tours in the Edna Valley wine region
- Discover the natural beauty of Montana de Oro State Park, with its rugged cliffs, secluded beaches, and scenic hiking trails.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Indianapolis, IN to San Luis Obispo, CA
Most Indianapolis, IN to San Luis Obispo, CA buses use the Indianapolis, E Washington St / N Delaware St (City/County Building) to San Luis Obispo, Santa Barbara Ave / High St (San Luis Obispo Railroad Museum) station pair. Use this guide to compare Indianapolis, IN and San Luis Obispo, CA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Getting to San Luis Obispo, Santa Barbara Ave / High St (San Luis Obispo Railroad Museum) from San Luis Obispo city centre
Most popular bus connections from Indianapolis, IN
More options for your journey from Indianapolis, IN to San Luis Obispo, CA
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