- Must visit
Denver Art Museum
One of the largest art museums in the West, known for Indigenous art, global collections, and striking architecture.
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The cheapest and fastest buses from Santa Ana, CA to Denver, CO
Showing times and prices for Jul 15
Cheapest price
$149
Average price
$149
Fastest journey
1 d 5 h 5 m
Average duration
1 d 6 h 58 m
Buses per day
2
Distance
1325 km
Cheap tickets
The best way to find a cheap bus ticket from Santa Ana, CA to Denver, CO is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Santa Ana, CA to Denver, CO will cost around $149 if you buy it on the day, but the cheapest tickets can be found for only $149.
Fast buses
It's difficult to get from Santa Ana, CA to Denver, CO without transferring at least 2 times.
· · 11:35 AM29h05Santa Ana, E Santa Ana Blvd (Train Station)5:40 PMDenver, Union Station$1491One-way2 transfers- · · 9:25 PM32h50Santa Ana, E Santa Ana Blvd (Train Station)7:15 AMDenver, Union Station$1491One-way2 transfers
- · · 11:35 AM29h05Santa Ana, E Santa Ana Blvd (Train Station)5:40 PMDenver, Union Station$1491One-way2 transfers
- · · 9:25 PM32h50Santa Ana, E Santa Ana Blvd (Train Station)7:15 AMDenver, Union Station$1491One-way2 transfers
Travel Information
Compare bus, train, and flight for Santa Ana, CA to Denver, CO
Omio recommends booking the flight as it is the most popular option from Santa Ana, CA to Denver, CO among Omio's users. If you are prioritising price take the bus with prices starting from $142. For those with little time consider booking a flight which can get you there in 2h 25m. The ticket price range depends on the travel mode: a bus costs an average of $142, and a train costs an average of $271.
Distance: 823 miles (1325 km)
Compare bus with
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
$193 Average price Cheapest | $271 Average price | $383 Average price | $203 Average price (fuel + tolls) |
29h 35m Average total duration 29h 5m Onboard + 30m Additional time* | 5h 25m Average total duration Fastest 2h 25m Onboard + 3h 0m Additional time* | 47h 53m Average total duration 47h 23m Onboard + 30m Additional time* | 14h 52m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Santa Ana, CA to Denver, CO is a bus with an average price of $193 (€159).
This is compared to other travel options from Santa Ana, CA to Denver, CO:
A bus is $79 (€65) less than a flight for this route with tickets for a flight from Santa Ana, CA to Denver, CO costing on average $271 (€224).
A bus is $190 (€157) less than a train for this route with tickets for a train from Santa Ana, CA to Denver, CO costing on average $383 (€315).
The fastest way to travel from Santa Ana, CA to Denver, CO is by flight with an average journey time of 2h 25m.
Other travel options to Denver, CO take longer:
Bus takes on average 29h 5m.
Train takes on average 47h 23m.
It's helpful to compare your options as there are 3 ways to travel between Santa Ana, CA and Denver, CO including taking a bus, train, and flight.
We recommend using the flight as it is the most popular way to get from Santa Ana, CA to Denver, CO among Omio's users.
Take the bus. On this route, it's both cheaper and quicker than driving.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Santa Ana, CA to Denver, CO Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 11:35AM | Arrival Time 05:40PM | Duration 29h05 | Departure days Everyday | Cheapest price $133 |
Operator Greyhound | Departure Time 09:25PM | Arrival Time 07:15AM | Duration 32h50 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $141 |
Live departures
Santa Ana, CA to Denver, CO bus times
The table below shows live departures for Santa Ana, CA to Denver, CO buses for today, Tuesday, July 14. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| · · | 11:35 AM Santa Ana, E Santa Ana Blvd (Train Station) | 29h05 | 5:40 PM Denver, Union Station | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Santa Ana, CA to Denver, CO by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Santa Ana, CA to Denver, CO buses with Omio?
Greyhound operates all buses services from Santa Ana, CA to Denver, CO.
Omio is an official ticket reseller for all your travel options from Santa Ana, CA to Denver, CO.
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Santa Ana, CA to Denver, CO.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Santa Ana, CA to Denver, CO.
Journey information
Overview: Bus from Santa Ana, CA to Denver, CO
USAUSA
Buses from Santa Ana, CA to Denver, CO run on average 2 times per day, taking around 29h 5m. Cheap bus tickets for this journey start at $142 (€117) if you book in advance.
The earliest bus runs at 08:46, the last at 21:20. The fastest bus covers the 823 miles (1325 km) distance in 29h 5m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 823 miles (1325 km) |
Average bus duration 29h 5m |
Cheapest ticket price $142 (€117) |
Buses per day 2 |
Fastest bus 29h 5m |
First bus 8:46 AM |
Last bus 9:20 PM |
Cheapest Month Nov |
Cheapest Day Sat |
High Season Oct - Dec |
Low Season Apr - Jun |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: Greyhound from Santa Ana, CA to Denver, COYou can travel by bus between Santa Ana, CA to Denver, CO with Greyhound for as low as $142 (€117). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
29h 5m
Cheapest Price
$142 (€117)
Greyhound frequency
2 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Complete guide to Denver, CO
Things to do in Denver, CO
Discover the best of Denver, CO — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Denver, CO trip today.
- Must visit
Denver Museum of Nature & Science
A major natural history museum with dinosaur fossils, space exhibits, wildlife dioramas, and rooftop city views.
- Recommended
History Colorado Center
This museum explores Colorado and Western heritage through Native history, artifacts, and regional storytelling.
- Must visit
Civic Center Park
Denver's landmark downtown park and civic heart, framed by museums, government buildings, festivals, and open lawns.
- Must visit
City Park
A scenic urban lake and park with skyline and mountain views, trails, boating, and one of Denver's best sunsets.
- Must visit
16th Street Mall
A lively pedestrian mall lined with shops, public art, and free shuttle service through the center of downtown Denver.
- Gluten-free
Denver Omelet
Denver omelet with ham, bell peppers, onions, and cheese. It is strongly associated with the city and remains a classic local breakfast order.
- Gluten-free
Colorado Green Chile
Green chile is a beloved Front Range staple, served as a pork-rich stew or smothered over burritos, fries, and breakfast plates across Denver.
Colorado Green Chile Cheeseburger
A juicy burger topped with roasted green chiles and cheese. It reflects Colorado's chile-loving comfort food culture and is common in Denver pubs.
Fruition Restaurant
Acclaimed fine dining restaurant focused on wood-fired New American cuisine, seasonal Colorado ingredients, and polished service in an elegant room.
El Taco de Mexico
Popular modern Mexican spot celebrated for green chile, tacos, and strong margaritas. Casual atmosphere with a long local following.
Sam's No. 3
Beloved neighborhood eatery serving creative breakfasts and brunch. A reliable place to try a Denver omelet in a relaxed, local setting.
US Dollar ($)
Moderate for a major US city: hotels and dining are mid-to-high, while transit is reasonable. Costs are usually lower than New York or San Francisco.
Average meal costs
- Budget
- $10-$18 for fast food or casual spots.
- Mid-range
- $20-$40 per person for a restaurant meal.
- Fine dining
- $60+ per person at upscale restaurants.
- Coffee
- $4-$6 for a cappuccino.
Tipping culture
Tip 18-20% at restaurants, $1-$2 per drink at bars, and 10-15% for taxis. Cafes often have tip screens; rounding up or $1 is common.
FAQs: Bus from Santa Ana, CA to Denver, CO
Find answers to the most common questions about traveling from Santa Ana, CA to Denver, CO by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Denver, CO, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Santa Ana, CA to Denver, CO can start from as little as $142 (€117) when you book in advance. The average bus ticket price for Santa Ana, CA to Denver, CO is $193 (€159) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Santa Ana, CA to Denver, CO is 29h 5m to travel the 823 miles (1325 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Santa Ana, CA to Denver, CO leaves at 8:46 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Santa Ana, CA to Denver, CO leaves at 9:20 PM.
There are 2 buses a day from Santa Ana, CA to Denver, CO which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Santa Ana, CA to Denver, CO, you can count on Greyhound for the best way to get you to Denver, CO. You can also check all possible bus companies who offer a service between Santa Ana, CA and Denver, CO and compare the amenities they offer before buying a bus ticket.
A trip to Denver, CO from Santa Ana, CA is worth doing but not as a day trip with a journey time of 29h 5m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Santa Ana, CA to Denver, CO is November.
It's helpful to compare your options as there are 3 ways to travel between Santa Ana, CA and Denver, CO including taking a bus, train, and flight.
Yes, there are bathrooms on board the bus from Santa Ana, CA to Denver, CO for bus company Greyhound.
Yes, the following accessibility options are available when taking the bus from Santa Ana, CA to Denver, CO:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Some of the most interesting sights to explore in Denver, CO are:
- Red Rocks Amphitheatre, a renowned open-air concert venue set amidst stunning natural rock formations
- Denver Art Museum, featuring an extensive collection of Native American art and contemporary works
- Denver Botanic Gardens, offering diverse plant displays and themed gardens
- Union Station, a historic transportation hub with shops, dining, and events
- Denver Museum of Nature & Science, showcasing exhibits on natural history, space, and anthropology.
The best things to do in Denver, CO include:
- Coors Field, home to the Colorado Rockies, offering baseball games and tours in a scenic downtown setting
- Larimer Square, a vibrant historic district with shopping, dining, and nightlife
- City Park, a large urban park with trails, lakes, and views of downtown Denver and the mountains
- Denver Zoo, featuring a wide variety of animals and interactive exhibits
- Cherry Creek Shopping Center, a premier retail destination with luxury brands and dining options.
Whether you can cancel your bus ticket from Santa Ana, CA to Denver, CO depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Santa Ana, CA to Denver, CO.
Yes, the following luggage options are included when booking a bus ticket from Santa Ana, CA to Denver, CO:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Santa Ana, CA to Denver, CO:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Santa Ana, CA to Denver, CO.
You can reserve your seat on the bus from Santa Ana, CA to Denver, CO with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Santa Ana, CA to Denver, CO with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Santa Ana, CA to Denver, CO with the following bus company: Greyhound.
Since neither Santa Ana, CA nor Denver, CO are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the flight as it is the most popular way to get from Santa Ana, CA to Denver, CO among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Denver, CO, travelers should be aware of pickpocketing and petty theft, especially in crowded areas like downtown and tourist attractions. Common scams include overpriced rides from unofficial taxi services and fraudulent ticket sellers near popular venues. It's advisable to use licensed transportation, stay vigilant in busy spots, and avoid sharing personal information with strangers to ensure safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Santa Ana, CA to Denver, CO
Most Santa Ana, CA to Denver, CO buses use the Santa Ana, E Santa Ana Blvd (Train Station) to Denver, Union Station station pair. Use this guide to compare Santa Ana, CA and Denver, CO bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Santa Ana
Arrival bus stations in Denver
Santa Ana, E Santa Ana Blvd (Train Station)
Denver, Union Station
City-centre transport
Getting to Denver, Union Station from Denver city centre
Bus0, 10, 15, 19 · 10m · $4 · every ~27 min
15 · 13m · $4 · every ~12 min
Most popular bus connections from Santa Ana, CA
More options for your journey from Santa Ana, CA to Denver, CO
Here are some other resources that might have the information you need
Most popular buses to and from Denver, CO and Santa Ana, CA
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