Santa Ana, CA to Chicago, IL bus with Greyhound

Thu, Nov 27
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1,000+ travel companies
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FlixBus
Alsa
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Rede Expressos
1,000+ travel companies
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The cheapest and fastest buses from Santa Ana, CA to Chicago, IL

Showing times and prices for Nov 27

Cheapest price

$864

Average price

$864

Fastest journey

2 d 5 h 40 m

Average duration

2 d 5 h 40 m

Buses per day

1

Distance

2787 km

Cheap tickets

The best way to find a cheap bus ticket from Santa Ana, CA to Chicago, IL is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Santa Ana, CA to Chicago, IL will cost around $864 if you buy it on the day, but the cheapest tickets can be found for only $864.

Fast buses

It's difficult to get from Santa Ana, CA to Chicago, IL without transferring at least 2 times.

Greyhound Mexico
09:15AM53h40
Santa Ana, CA
02:55PMChicago, IL
$8641One-way
2 transfers

Travel Information

Compare train, bus, and flight for Santa Ana, CA to Chicago, IL

Omio recommends booking the train as it is the most popular option from Santa Ana, CA to Chicago, IL among Omio's users. If you are prioritising price take the bus with prices starting from €102. For those with little time consider booking a flight which can get you there in 4h 9m. The ticket price range depends on the travel mode: a bus costs an average of €102, and a flight costs an average of €168.

Distance: 1731 miles (2787 km)

Compare bus with

Bus
Most popular
Train
Flight

€172

Average price

Cheapest

€214

Average price

€288

Average price

53h 11m

Average total duration

52h 41m

Onboard

+

30m

Additional time*

43h 18m

Average total duration

42h 48m

Onboard

+

30m

Additional time*

7h 9m

Average total duration

Fastest

4h 9m

Onboard

+

3h 0m

Additional time*

Direct Options

Direct Options

Direct Options

Live departures

Santa Ana, CA to Chicago, IL bus times

The table below shows live departures for Santa Ana, CA to Chicago, IL buses for tomorrow, Thursday, November 27. You can also manually refresh the results below to see updated bus journeys.

Last updated at 11:32 AM
ProviderDepartsDurationArrivesTransfers
Tickets
greyhound9:15 AM Santa Ana, CA
53h40
2:55 PM Chicago, IL2 transfers

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Santa Ana, CA to Chicago, IL by train, bus, or flight

Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Thu
Nov 27
Fri
Nov 28
Sat
Nov 29
Sun
Nov 30
Mon
Dec 01
Tue
Dec 02
Wed
Dec 03

Journey information

Overview: Bus from Santa Ana, CA to Chicago, IL

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Buses from Santa Ana, CA to Chicago, IL run on average 3 times per day, taking around 52h 41m. Cheap bus tickets for this journey start at $126 (€102) if you book in advance.

The earliest bus runs at 06:10, the last at 22:00. The fastest bus covers the 1731 miles (2787 km) distance in 51h 40m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
1731 miles (2787 km)
Average bus duration
52h 41m
Cheapest ticket price
$126 (€102)
Buses per day
3
Fastest bus
51h 40m
First bus
06:10
Last bus
22:00
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: Greyhound from Santa Ana, CA to Chicago, ILYou can travel by bus between Santa Ana, CA to Chicago, IL with Greyhound for as low as $126 (€102). When you search for schedules and tickets, Omio will show you the best journey

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
52h 30m
Cheapest Price
$126 (€102)
Greyhound frequency
1 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.

FAQs: Bus from Santa Ana, CA to Chicago, IL

Find answers to the most common questions about traveling from Santa Ana, CA to Chicago, IL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Chicago, IL, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Santa Ana, CA to Chicago, IL can start from as little as $976 (€792) when you book in advance. The average bus ticket price for Santa Ana, CA to Chicago, IL is $976 (€792); however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
On average the Santa Ana, CA to Chicago, IL bus travel time is 53 h 40 min   for the 1727 mile (2786 km) long route, but the duration can vary if you travel on weekends and holidays.
The first bus from Santa Ana, CA to Chicago, IL leaves at 6: 00AM. Plan your trip with the Journey Planner   from Omio.
The last bus from Santa Ana, CA to Chicago, IL leaves at 10: 35PM.
There are 4 buses a day from Santa Ana, CA to Chicago, IL which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Santa Ana, CA to Chicago, IL, you can count on Greyhound for the best way to get you to Chicago, IL. You can also check all possible bus companies who offer a service between Santa Ana, CA and Chicago, IL and compare the amenities they offer before buying a bus ticket.
The cheapest month to travel from Santa Ana, CA to Chicago, IL by bus is September.
You have options as you can travel from Santa Ana, CA to Chicago, IL 2 different ways: train or bus.
Yes, the following accessibility options are available when taking the bus from Santa Ana, CA to Chicago, IL:
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Santa Ana, CA to Chicago, IL for bus company Greyhound.
Some of the most interesting sights to explore in Chicago, IL are:
  • Millennium Park, a public park known for its modern art installations and the iconic Cloud Gate sculpture
  • Art Institute of Chicago, a renowned museum housing an extensive collection of art from around the world
  • Navy Pier, a popular entertainment destination featuring rides, restaurants, and lakefront views
  • Willis Tower Skydeck, an observation deck offering panoramic views of the city from one of the tallest buildings in the Western Hemisphere
  • Field Museum, a natural history museum with vast exhibits including the famous T. Rex skeleton, Sue.
The best things to do in Chicago, IL include:
  • Museum of Science and Industry, an interactive museum featuring exhibits on science, technology, and industry
  • Explore the vibrant neighborhoods of Chicago, such as Wicker Park and Lincoln Park, known for their unique shops and eateries
  • Take a river cruise to see the city's iconic architecture from a different perspective
  • Attend a live performance at the historic Chicago Theatre
  • Enjoy a day at Lincoln Park Zoo, one of the oldest zoos in the U. S. Offering free admission.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Whether you can cancel your bus ticket from Santa Ana, CA to Chicago, IL depends on the bus company:
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.

To find the cheapest bus tickets for your trip from Santa Ana, CA to Chicago, IL, follow these tips:

  • Book in advance: Tickets are often cheaper when booked early.
  • Be flexible with dates and times: Traveling during off-peak hours or on weekdays can help you save money.
  • Use our search filters: Sort results by price to quickly identify the most affordable options.
  • Look for special deals or discounts: Check for promotions or discounts available on our website and app.
  • Start your search now and compare ticket prices to find the best deal!

    Yes, there is food available to purchase on board the bus from Santa Ana, CA to Chicago, IL.
    Yes, the following luggage options are included when booking a bus ticket from Santa Ana, CA to Chicago, IL:
    • Greyhound
      • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
    Yes, the following additional luggage options are available when booking a bus ticket from Santa Ana, CA to Chicago, IL:
    • Greyhound
      • $15 per additional bag.
    Unfortunately, pets are not allowed on the bus from Santa Ana, CA to Chicago, IL.
    You can reserve your seat on the bus from Santa Ana, CA to Chicago, IL with the following bus company: Greyhound
    Yes, there are USB plugs on board the bus from Santa Ana, CA to Chicago, IL with the following bus company: Greyhound.
    Yes, there is Wifi on board the bus from Santa Ana, CA to Chicago, IL with the following bus company: Greyhound.

    popular bus stations

    Popular bus stations from Santa Ana, CA to Chicago, IL

    Santa Ana
    Chicago
    The major bus station for departures in Santa Ana is Santa Ana, E Santa Ana Blvd (Train Station). Find all the information you need to know about services, amenities and connections at Santa Ana, E Santa Ana Blvd (Train Station) for your trip from Santa Ana to Chicago.
    Santa Ana, E Santa Ana Blvd (Train Station)
    information
    HomeBusesBuses in USABus tickets to Chicago, ILSanta Ana, CA to Chicago, IL bus

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