San Diego to San Luis Obispo, CA bus

Amtrak is the main bus company in the United States and operates medium and long-distance intercity services in 46 American states and 3 Canadian provinces. With over 300 Amtrak buses running daily, you can travel by bus across America and explore destinations near and far. Take the Acela bus for high-speed services connecting popular cities in the Northeast, the Coast Starlight to travel up and down the stunning West Coast or the Empire Builder to travel from Chicago to the Midwest and the Pacific Northwest among others. Amtrak offers different class options to suit any traveler’s budget with classes like Coach, Business, First and the Sleeper Class, where you can book a Roomette, Bedroom, and Bedroom suite among others for night travel. When you book your bus journey between San Diego and San Luis Obispo, CA, you can choose between ticket types like Saver, Value, Flexible, Business and Premium.