Travel Information
Compare train, bus, and flight for San Diego, CA to San Luis Obispo, CA
Omio recommends booking the train as it is the most popular option from San Diego, CA to San Luis Obispo, CA among Omio's users. If you are prioritising price take the train with prices starting from $67. For those with little time consider booking a flight which can get you there in 1h 16m. The ticket price range depends on the travel mode: a train costs an average of $67, and a flight costs an average of $128.
Distance: 267 miles (431 km)
Compare bus with
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$69 Average price | $69 Average price Cheapest | $329 Average price | $70 Average price (fuel + tolls) |
8h 49m Average total duration 8h 19m Onboard + 30m Additional time* | 9h 6m Average total duration 8h 36m Onboard + 30m Additional time* | 4h 16m Average total duration Fastest 1h 16m Onboard + 3h 0m Additional time* | 5h 15m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from San Diego, CA to San Luis Obispo, CA:
A train is $0.09 (€0.07) less than a bus for this route with tickets for a bus from San Diego, CA to San Luis Obispo, CA costing on average $69 (€56).
A train is $260 (€210) less than a flight for this route with tickets for a flight from San Diego, CA to San Luis Obispo, CA costing on average $329 (€266).
Other travel options to San Luis Obispo, CA take longer:
Bus takes on average 8h 19m.
Train takes on average 8h 36m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
San Diego, CA to San Luis Obispo, CA Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound Mexico | Departure Time 07:25PM | Arrival Time 01:25PM | Duration 18h00 | Departure days Tue, Sat, Sun | Cheapest price $69 |
Live departures
San Diego, CA to San Luis Obispo, CA bus times
The table below shows live departures for San Diego, CA to San Luis Obispo, CA buses for today, Tuesday, June 16. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 7:25 PM San Diego, CA | 18h00 | 1:25 PM San Luis Obispo, CA | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets San Diego, CA to San Luis Obispo, CA by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book San Diego, CA to San Luis Obispo, CA buses with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Greyhound to find the best option for your trip from San Diego, CA to San Luis Obispo, CA.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from San Diego, CA to San Luis Obispo, CA.
Why book with Omio over Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Greyhound to find the best option for your trip from San Diego, CA to San Luis Obispo, CA.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from San Diego, CA to San Luis Obispo, CA.
Journey information
Overview: Bus from San Diego, CA to San Luis Obispo, CA
Buses from San Diego, CA to San Luis Obispo, CA run on average 10 times per day, taking around 8h 19m. Cheap bus tickets for this journey start at $69 (€56) but you can travel from only $67 (€54) by train.
The earliest bus runs at 03:45, the last at 21:25. The fastest bus covers the 267 miles (431 km) distance in 18h 0m.
Distance 267 miles (431 km) |
Average bus duration 8h 19m |
Cheapest ticket price $69 (€56) |
Buses per day 10 |
Fastest bus 18h 0m |
First bus 3:45 AM |
Last bus 9:25 PM |
Cheapest Month Jan |
Cheapest Day Sun |
High Season Oct - Dec |
Low Season Jul - Sep |
Busiest Day Thu |
Least Busy Day Thu |
Best time to book 84 days |
Bus providers: FlixBus, Greyhound from San Diego, CA to San Luis Obispo, CAYou can travel by bus between San Diego, CA to San Luis Obispo, CA with FlixBus, Greyhound for as low as $67 (€54). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Greyhound
FAQs: Bus from San Diego, CA to San Luis Obispo, CA
Find answers to the most common questions about traveling from San Diego, CA to San Luis Obispo, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Luis Obispo, CA, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Bubblegum Alley, a narrow alleyway famous for its walls covered in layers of chewed gum left by visitors
- Mission San Luis Obispo de Tolosa, a historic Spanish mission founded in 1772 with a museum and beautiful gardens
- Bishop Peak, a popular hiking destination offering panoramic views of the city and surrounding landscapes
- San Luis Obispo Museum of Art, a contemporary art museum showcasing works by regional and national artists
- Avila Beach, a nearby coastal spot known for its sandy shores and scenic pier.
- Stroll through Downtown SLO, a vibrant area with shops, restaurants, and the famous Thursday Night Farmers' Market
- Attend a performance at the Fremont Theater, a historic venue known for its art deco architecture and live events
- Visit the San Luis Obispo Children's Museum, offering interactive exhibits and activities for kids
- Explore the local wineries and vineyards, enjoying tastings and tours in the Edna Valley wine region
- Discover the natural beauty of Montana de Oro State Park, with its rugged cliffs, secluded beaches, and scenic hiking trails.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from San Diego, CA to San Luis Obispo, CA
More options for your journey from San Diego, CA to San Luis Obispo, CA
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