San Diego, CA to San Luis Obispo, CA bus with Greyhound

Tue, Sep 15
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The cheapest and fastest buses from San Diego, CA to San Luis Obispo, CA

Showing times, prices and bookable tickets for Sep 15

Cheapest price on Sep 15

$69

Average ticket price on Sep 15

$69

Fastest journey on Sep 15

18 h

Average journey duration on Sep 15

18 h

Buses on Sep 15

1

Distance

431 km

Cheap tickets

The best way to find a cheap bus ticket from San Diego, CA to San Luis Obispo, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from San Diego, CA to San Luis Obispo, CA will cost around $69 if you buy it on the day, but the cheapest tickets can be found for only $69.

Fast buses

It's difficult to get from San Diego, CA to San Luis Obispo, CA without transferring at least once.

  • Greyhound Mexico
    7:25 PM18h00
    San Diego, CA
    1:25 PMSan Luis Obispo, CA
    $691One-way
    1 transfer

Travel Information

Compare train, bus, and flight for San Diego, CA to San Luis Obispo, CA

Omio recommends booking the train as it is the most popular option from San Diego, CA to San Luis Obispo, CA among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $58 For those with little time, consider booking a flight, which has an average total journey time of 6h 13m. Average ticket prices depend on the travel mode: a bus costs an average of $58, while a flight costs an average of $737.

Distance: 267 miles (431 km)

Compare bus with

Bus
Most popular
Train
Flight
Driving

$58

Average price

Cheapest

$102

Average price

$737

Average price

$71

Average price

(fuel + tolls)

8h 58m

Average total duration

8h 28m

Onboard

+

30m

Additional time*

8h 52m

Average total duration

8h 22m

Onboard

+

30m

Additional time*

6h 13m

Average total duration

Fastest

4h 13m

Onboard

+

2h 0m

Additional time*

5h 15m

Average total duration

(door-to-door)

FlixBus

Most popular bus company

Amtrak

Most popular train company

United

Most popular airline

Your own car or car rental

Direct Options

Direct Options

Direct Options

Direct Options

The cheapest way to travel from San Diego, CA to San Luis Obispo, CA is a bus with an average price of $58.

This is compared to other travel options from San Diego, CA to San Luis Obispo, CA:

A bus is $44 less than a train for this route with tickets for a train from San Diego, CA to San Luis Obispo, CA costing on average $102.

A bus is $679 less than a flight for this route with tickets for a flight from San Diego, CA to San Luis Obispo, CA costing on average $737.

The fastest way to travel from San Diego, CA to San Luis Obispo, CA is by flight with an average journey time of 4h 13m.

Other travel options to San Luis Obispo, CA take longer:

Train takes on average 8h 22m.

Bus takes on average 8h 28m.

It's helpful to compare your options as there are 3 ways to travel between San Diego, CA and San Luis Obispo, CA including taking a train, bus, and flight.
We recommend using the train as it is the most popular way to get from San Diego, CA to San Luis Obispo, CA among Omio's users.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.

Tickets start at around $58 compared to roughly $71 in fuel and tolls — a saving of about $13. The journey takes 8h 28m versus 5h 15m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.

Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.

San Diego, CA to San Luis Obispo, CA Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
Greyhound Mexico
Departure Time
07:25PM
Arrival Time
01:25PM
Duration
18h00
Departure days
Tue, Sat, Sun
Cheapest price
$69

Compare prices and tickets San Diego, CA to San Luis Obispo, CA by train, bus, or flight

Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Tue
Sep 15
Wed
Sep 16
Thu
Sep 17
Fri
Sep 18
Sat
Sep 19
Sun
Sep 20
Mon
Sep 21

Why should you book San Diego, CA to San Luis Obispo, CA buses with Omio?

FlixBus as well as Greyhound offer buses services from San Diego, CA to San Luis Obispo, CA.
Omio is an official ticket reseller for all your travel options from San Diego, CA to San Luis Obispo, CA.

Why book with Omio vs FlixBus?

  • Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Greyhound to find the best option for your trip from San Diego, CA to San Luis Obispo, CA.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from San Diego, CA to San Luis Obispo, CA.

Why book with Omio over Wanderu or Trainline?

  • Compare with other providers: On Omio, you can also compare tickets for the likes of Greyhound to find the best option for your trip from San Diego, CA to San Luis Obispo, CA.
  • Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from San Diego, CA to San Luis Obispo, CA.

Journey information

Overview: Bus from San Diego, CA to San Luis Obispo, CA

USAUSA
USAUSA
Icon of bus

Buses from San Diego, CA to San Luis Obispo, CA run on average 2 times per day, taking around 8h 28m. Cheap bus tickets for this journey start at $36 if you book in advance.

The earliest bus runs at 03:45, the last at 21:25. The fastest bus covers the 267 miles (431 km) distance in 8h 5m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
267 miles (431 km)
Average bus duration
8h 28m
Cheapest ticket price
$36
Buses per day
2
Fastest bus
8h 5m
First bus
3:45 AM
Last bus
9:25 PM
Cheapest Month
Jan
Cheapest Day
Sun
High Season
Jul - Sep
Low Season
Jan - Mar
Busiest Day
Wed
Least Busy Day
Wed
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: Greyhound, FlixBus from San Diego, CA to San Luis Obispo, CAYou can travel by bus between San Diego, CA to San Luis Obispo, CA with Greyhound, FlixBus for as low as $68. When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
8h 5m
Cheapest FlixBus Price
$51
FlixBus frequency
1 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
8h 50m
Cheapest Greyhound Price
$36
Greyhound frequency
1 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.

FAQs: Bus from San Diego, CA to San Luis Obispo, CA

Find answers to the most common questions about traveling from San Diego, CA to San Luis Obispo, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Luis Obispo, CA, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from San Diego, CA to San Luis Obispo, CA can start from as little as $36 when you book in advance. The average bus ticket price for San Diego, CA to San Luis Obispo, CA is $58 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from San Diego, CA to San Luis Obispo, CA is 8h 5m to travel the 267 miles (431 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from San Diego, CA to San Luis Obispo, CA leaves at 3:45 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from San Diego, CA to San Luis Obispo, CA leaves at 9:25 PM.
There are 2 buses a day from San Diego, CA to San Luis Obispo, CA which require at least one change with FlixBus, Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from San Diego, CA to San Luis Obispo, CA, you can count on FlixBus, Greyhound for the best way to get you to San Luis Obispo, CA. You can also check all possible bus companies who offer a service between San Diego, CA and San Luis Obispo, CA and compare the amenities they offer before buying a bus ticket.
When departing from San Diego, CA , you have various bus station options to start your journey from including San Diego, Congress Street (Old Town Park), CA, San Diego, San Ysidro Transit Center . When arriving in San Luis Obispo, CA , you can end your journey in bus stations like San Luis Obispo, Santa Barbara Ave / High St (San Luis Obispo Railroad Museum), CA .Passengers board the bus most frequently from San Diego, Congress Street (Old Town Park), CA, which is located around 3 miles (5 km) away from the city centre, and they get off the bus at San Luis Obispo, Santa Barbara Ave / High St (San Luis Obispo Railroad Museum), CA, located 1 away from the city centre.
A trip to San Luis Obispo, CA from San Diego, CA is worth doing but not as a day trip with a journey time of 8h 5m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from San Diego, CA to San Luis Obispo, CA is January.
It's helpful to compare your options as there are 3 ways to travel between San Diego, CA and San Luis Obispo, CA including taking a train, bus, and flight.
Yes, the following accessibility options are available when taking the bus from San Diego, CA to San Luis Obispo, CA:
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from San Diego, CA to San Luis Obispo, CA for bus company FlixBus, Greyhound.
Some of the most interesting sights to explore in San Luis Obispo, CA are:
  • Bubblegum Alley, a narrow alleyway famous for its walls covered in layers of chewed gum left by visitors
  • Mission San Luis Obispo de Tolosa, a historic Spanish mission founded in 1772 with a museum and beautiful gardens
  • Bishop Peak, a popular hiking destination offering panoramic views of the city and surrounding landscapes
  • San Luis Obispo Museum of Art, a contemporary art museum showcasing works by regional and national artists
  • Avila Beach, a nearby coastal spot known for its sandy shores and scenic pier.
The best things to do in San Luis Obispo, CA include:
  • Stroll through Downtown SLO, a vibrant area with shops, restaurants, and the famous Thursday Night Farmers' Market
  • Attend a performance at the Fremont Theater, a historic venue known for its art deco architecture and live events
  • Visit the San Luis Obispo Children's Museum, offering interactive exhibits and activities for kids
  • Explore the local wineries and vineyards, enjoying tastings and tours in the Edna Valley wine region
  • Discover the natural beauty of Montana de Oro State Park, with its rugged cliffs, secluded beaches, and scenic hiking trails.
Whether you can cancel your bus ticket from San Diego, CA to San Luis Obispo, CA depends on the bus companies:
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company FlixBus, Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from San Diego, CA to San Luis Obispo, CA.
Yes, the following luggage options are included when booking a bus ticket from San Diego, CA to San Luis Obispo, CA:
  • Greyhound
    • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
  • FlixBus
    • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from San Diego, CA to San Luis Obispo, CA:
  • Greyhound
    • $15 per additional bag.
  • FlixBus
    • Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from San Diego, CA to San Luis Obispo, CA. The following conditions apply:
  • FlixBus
    • Small pets in carriers allowed
    • guide dogs travel for free.
You can reserve your seat on the bus from San Diego, CA to San Luis Obispo, CA with the following bus company: FlixBus, Greyhound
Yes, there are USB plugs on board the bus from San Diego, CA to San Luis Obispo, CA with the following bus company: FlixBus, Greyhound.
Yes, there is Wifi on board the bus from San Diego, CA to San Luis Obispo, CA with the following bus company: FlixBus, Greyhound.
Since neither San Diego, CA nor San Luis Obispo, CA are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the train as it is the most popular way to get from San Diego, CA to San Luis Obispo, CA among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In San Luis Obispo, CA, travelers should be cautious of petty theft, especially in crowded areas and parking lots. Common scams include overcharging by taxis and occasional fake charity solicitations. It is advisable to avoid leaving valuables visible in vehicles and to use reputable transportation services. Overall, the city is considered relatively safe, but staying alert to personal belongings and using common sense helps ensure a secure visit.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from San Diego, CA to San Luis Obispo, CA

Most San Diego, CA to San Luis Obispo, CA buses use the San Diego, Congress Street (Old Town Park) to San Luis Obispo, Santa Barbara Ave / High St (San Luis Obispo Railroad Museum) station pair. Use this guide to compare San Diego, CA and San Luis Obispo, CA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.

Departure bus stations in San Diego
Arrival bus stations in San Luis Obispo

Which San Diego, CA station do buses to San Luis Obispo, CA leave from?

Buses from San Diego, CA to San Luis Obispo, CA leave from San Diego, Congress Street (Old Town Park). The station is 3 miles (6 km) from San Diego, CA city centre at Congress St, San Diego, CA 92110, USA.
San Diego, Congress Street (Old Town Park)Congress St, San Diego, CA 92110, USAWifiParkingDiningATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to San Diego, Congress Street (Old Town Park) from San Diego city centre

San Diego, Congress Street (Old Town Park) is 5 km from San Diego city centre. Public transport options include:

BusFlixBus 2017 · 20m · $1
83 · 26m · $6
TramGreen, Blue, Event · 16m · every ~18 min
Blue · 21m · every ~9 min

San Diego, Congress Street (Old Town Park) bus station facilities and services

San Diego, Congress Street (Old Town Park) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Food and drink

Food options include: Several dining options nearby.

Wi-Fi and ATMs

Wi-Fi is available at San Diego, Congress Street (Old Town Park). ATMs are available at San Diego, Congress Street (Old Town Park).

Tickets and information

Ticket office support is available at San Diego, Congress Street (Old Town Park).

Parking, taxis and toilets

Available at San Diego, Congress Street (Old Town Park): Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at San Diego, Congress Street (Old Town Park): Wheelchair accessible routes available.

San Diego, San Ysidro Transit CenterSan Ysidro Station, San Diego, CA 92173, USAWifiParkingDiningATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to San Diego, San Ysidro Transit Center from San Diego city centre

San Diego, San Ysidro Transit Center is 22 km from San Diego city centre. Public transport options include:

BusFlixBus 2017 · 25m · $2
910 · 41m · $6
TramBlue · 41m · $17 · every ~14 min
Blue · 43m · $17 · every ~14 min

San Diego, San Ysidro Transit Center bus station facilities and services

San Diego, San Ysidro Transit Center has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Food and drink

Food options include: Several fast food eateries located nearby.

Wi-Fi and ATMs

Wi-Fi is available at San Diego, San Ysidro Transit Center. ATMs are available near the entrance.

Tickets and information

Ticket office support is available at San Diego, San Ysidro Transit Center.

Parking, taxis and toilets

Available at San Diego, San Ysidro Transit Center: Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at San Diego, San Ysidro Transit Center: Wheelchair accessible with ramps.

Most popular buses to and from San Luis Obispo, CA and San Diego, CA

HomeBusesBuses in USABus tickets to San Luis Obispo, CASan Diego, CA to San Luis Obispo, CA bus

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