Travel Information
Compare train, bus, and flight for San Diego, CA to San Luis Obispo, CA
Omio recommends booking the train as it is the most popular option from San Diego, CA to San Luis Obispo, CA among Omio's users. If you are prioritising price take the bus with prices starting from €29. For those with little time consider booking a flight which can get you there in 1h 16m. The ticket price range depends on the travel mode: a bus costs an average of €29, and a flight costs an average of €86.
Distance: 267 miles (431 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
€46 Average price Cheapest | €56 Average price | €203 Average price |
8h 47m Average total duration 8h 17m Onboard + 30m Additional time* | 9h 5m Average total duration 8h 35m Onboard + 30m Additional time* | 4h 16m Average total duration Fastest 1h 16m Onboard + 3h 0m Additional time* |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Compare prices and tickets San Diego, CA to San Luis Obispo, CA by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Bus from San Diego, CA to San Luis Obispo, CA
Buses from San Diego, CA to San Luis Obispo, CA run on average 11 times per day, taking around 8h 17m. Cheap bus tickets for this journey start at $36 (€29) if you book in advance.
The earliest bus runs at 03:45, the last at 21:25. The fastest bus covers the 267 miles (431 km) distance in 8h 35m.
Distance 267 miles (431 km) |
Average bus duration 8h 17m |
Cheapest ticket price $36 (€29) |
Buses per day 11 |
Fastest bus 8h 35m |
First bus 03:45 |
Last bus 21:25 |
Bus providers: FlixBus, Greyhound from San Diego, CA to San Luis Obispo, CAYou can travel by bus between San Diego, CA to San Luis Obispo, CA with FlixBus, Greyhound for as low as $36 (€29). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Greyhound
FAQs: Bus from San Diego, CA to San Luis Obispo, CA
Find answers to the most common questions about traveling from San Diego, CA to San Luis Obispo, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Luis Obispo, CA, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Bubblegum Alley, a narrow alleyway famous for its walls covered in layers of chewed gum left by visitors
- Mission San Luis Obispo de Tolosa, a historic Spanish mission founded in 1772 with a museum and beautiful gardens
- Bishop Peak, a popular hiking destination offering panoramic views of the city and surrounding landscapes
- San Luis Obispo Museum of Art, a contemporary art museum showcasing works by regional and national artists
- Avila Beach, a nearby coastal spot known for its sandy shores and scenic pier.
- Stroll through Downtown SLO, a vibrant area with shops, restaurants, and the famous Thursday Night Farmers' Market
- Attend a performance at the Fremont Theater, a historic venue known for its art deco architecture and live events
- Visit the San Luis Obispo Children's Museum, offering interactive exhibits and activities for kids
- Explore the local wineries and vineyards, enjoying tastings and tours in the Edna Valley wine region
- Discover the natural beauty of Montana de Oro State Park, with its rugged cliffs, secluded beaches, and scenic hiking trails.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
To find the cheapest bus tickets for your trip from San Diego, CA to San Luis Obispo, CA, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from San Diego, CA to San Luis Obispo, CA
More options for your journey from San Diego, CA to San Luis Obispo, CA
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