The cheapest and fastest buses from San Diego, CA to San Luis Obispo, CA
Cheapest price
$69
Average price
$69
Fastest journey
18 h
Average duration
18 h
Buses per day
1
Distance
431 km
The best way to find a cheap bus ticket from San Diego, CA to San Luis Obispo, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from San Diego, CA to San Luis Obispo, CA will cost around $69 if you buy it on the day, but the cheapest tickets can be found for only $69.
It's difficult to get from San Diego, CA to San Luis Obispo, CA without transferring at least once.
7:25 PM18h00San Diego, CA1:25 PMSan Luis Obispo, CA$691One-way1 transfer
7:25 PM18h00San Diego, CA1:25 PMSan Luis Obispo, CA$691One-way1 transfer
Journey information
Overview: Bus from San Diego, CA to San Luis Obispo, CA
Buses from San Diego, CA to San Luis Obispo, CA run on average 10 times per day, taking around 8h 19m. Cheap bus tickets for this journey start at $69 but you can travel from only $67 by train.
The earliest bus runs at 03:45, the last at 21:25. The fastest bus covers the 267 miles (431 km) distance in 18h 0m.
Distance 267 miles (431 km) |
Average bus duration 8h 19m |
Cheapest ticket price $69 |
Buses per day 10 |
Fastest bus 18h 0m |
First bus 3:45 AM |
Last bus 9:25 PM |
Cheapest Month Jan |
Cheapest Day Sun |
High Season Oct - Dec |
Low Season Jul - Sep |
Busiest Day Thu |
Least Busy Day Thu |
Best time to book 84 days |
San Diego, CA to San Luis Obispo, CA Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound Mexico | Departure Time 07:25PM | Arrival Time 01:25PM | Duration 18h00 | Departure days Tue, Sat, Sun | Cheapest price $69 |
Why should you book San Diego, CA to San Luis Obispo, CA buses with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Greyhound to find the best option for your trip from San Diego, CA to San Luis Obispo, CA.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from San Diego, CA to San Luis Obispo, CA.
Why book with Omio over Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Greyhound to find the best option for your trip from San Diego, CA to San Luis Obispo, CA.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from San Diego, CA to San Luis Obispo, CA.
Bus providers: FlixBus, Greyhound from San Diego, CA to San Luis Obispo, CAYou can travel by bus between San Diego, CA to San Luis Obispo, CA with FlixBus, Greyhound for as low as $67. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Greyhound
FAQs: Bus from San Diego, CA to San Luis Obispo, CA
Find answers to the most common questions about traveling from San Diego, CA to San Luis Obispo, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Luis Obispo, CA, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from San Diego, CA to San Luis Obispo, CA
Most San Diego, CA to San Luis Obispo, CA buses use the San Diego, Congress Street (Old Town Park) to San Luis Obispo, Santa Barbara Ave / High St (San Luis Obispo Railroad Museum) station pair. Use this guide to compare San Diego, CA and San Luis Obispo, CA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Getting to San Diego, Congress Street (Old Town Park) from San Diego city centre
Getting to San Diego, San Ysidro Transit Center from San Diego city centre
Getting to San Luis Obispo, Santa Barbara Ave / High St (San Luis Obispo Railroad Museum) from San Luis Obispo city centre
More options for your journey from San Diego, CA to San Luis Obispo, CA
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