Travel Information
Compare bus, train, and flight for Santa Ana, CA to Phoenix, AZ
Omio recommends booking the bus as it is the most popular option from Santa Ana, CA to Phoenix, AZ among Omio's users. If you are prioritising price take the bus with prices starting from $52. For those with little time consider booking a flight which can get you there in 1h 23m. The ticket price range depends on the travel mode: a bus costs an average of $52, and a flight costs an average of $43.
Distance: 334 miles (538 km)
Compare bus with
Most popular Bus | Flight | Train |
|---|---|---|
$78 Average price Cheapest | $201 Average price | $128 Average price |
8h 27m Average total duration 7h 57m Onboard + 30m Additional time* | 4h 23m Average total duration Fastest 1h 23m Onboard + 3h 0m Additional time* | 12h 56m Average total duration 12h 26m Onboard + 30m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
Santa Ana, CA to Phoenix, AZ bus times
The table below shows live departures for Santa Ana, CA to Phoenix, AZ buses for today, Sunday, March 22. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 4:45 PM Santa Ana, CA | 14h00 | 6:45 AM Phoenix, AZ | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Santa Ana, CA to Phoenix, AZ by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Mar 29
Why should you book Santa Ana, CA to Phoenix, AZ buses with Omio?
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of FlixBus to find the best option for your trip from Santa Ana, CA to Phoenix, AZ.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Santa Ana, CA to Phoenix, AZ.
Why book with Omio over Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus to find the best option for your trip from Santa Ana, CA to Phoenix, AZ.
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Santa Ana, CA to Phoenix, AZ.
Journey information
Overview: Bus from Santa Ana, CA to Phoenix, AZ
Buses from Santa Ana, CA to Phoenix, AZ run on average 6 times per day, taking around 7h 57m. Cheap bus tickets for this journey start at $52 (€42) but you can travel from only $43 (€35) by flight.
The earliest bus runs at 01:25, the last at 22:50. The fastest bus covers the 334 miles (538 km) distance in 8h 0m.
Distance 334 miles (538 km) |
Average bus duration 7h 57m |
Cheapest ticket price $52 (€42) |
Buses per day 6 |
Fastest bus 8h 0m |
First bus 01:25 |
Last bus 22:50 |
Cheapest month Jan |
Cheapest day Thu |
High season Jan - Mar |
Low season Apr - Jun |
Best day to book ahead 7 days |
Bus providers: Greyhound, FlixBus from Santa Ana, CA to Phoenix, AZYou can travel by bus between Santa Ana, CA to Phoenix, AZ with Greyhound, FlixBus for as low as $43 (€35). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Greyhound
FAQs: Bus from Santa Ana, CA to Phoenix, AZ
Find answers to the most common questions about traveling from Santa Ana, CA to Phoenix, AZ by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Phoenix, AZ, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Desert Botanical Garden, a 140-acre garden showcasing a vast collection of arid-land plants and desert landscapes
- Heard Museum, a renowned museum dedicated to the advancement of American Indian art and culture
- Phoenix Art Museum, the largest art museum in the southwestern United States featuring diverse collections and exhibitions
- Camelback Mountain, a popular hiking destination offering panoramic views of the city and surrounding desert
- Papago Park, a scenic park known for its distinctive geological formations and recreational opportunities.
- Musical Instrument Museum, a unique museum showcasing instruments from around the world
- South Mountain Park and Preserve, offering extensive trails and breathtaking views of the desert landscape
- Roosevelt Row, a vibrant arts district known for its galleries, murals, and local eateries
- Phoenix Zoo, a family-friendly attraction with a wide variety of animals and interactive exhibits
- Taliesin West, the winter home and architectural school of Frank Lloyd Wright, offering tours of its stunning design.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Santa Ana, CA to Phoenix, AZ
Most popular bus connections from Santa Ana, CA
More options for your journey from Santa Ana, CA to Phoenix, AZ
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