Santa Ana, CA to San Francisco, CA bus with Greyhound

Fri, Nov 28
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Rede Expressos
1,000+ travel companies
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The cheapest and fastest buses from Santa Ana, CA to San Francisco, CA

Showing times and prices for Nov 28

Cheapest price

$118

Average price

$118

Fastest journey

10 h 50 m

Average duration

10 h 50 m

Buses per day

1

Distance

608 km

Cheap tickets

The best way to find a cheap bus ticket from Santa Ana, CA to San Francisco, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Santa Ana, CA to San Francisco, CA will cost around $118 if you buy it on the day, but the cheapest tickets can be found for only $118.

Fast buses

Of the 1 buses that leave Santa Ana, CA for San Francisco, CA on Fri, Nov 28, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.

On Fri, Nov 28 the direct buses cover the 608 km distance in an average of 10 h 50 m but if you time it right, some buses will get you there in just 10 h 50 m .

On Fri, Nov 28 the slowest buses will take 10 h 50 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

FlixBus
04:15PM10h50
Santa Ana, CA
03:05AMSan Francisco, CA
$1181One-way
0 transfers

Travel Information

Compare train, bus, and flight for Santa Ana, CA to San Francisco, CA

Omio recommends booking the train as it is the most popular option from Santa Ana, CA to San Francisco, CA among Omio's users. If you are prioritising price take the train with prices starting from €61. For those with little time consider booking a flight which can get you there in 1h 31m. The ticket price range depends on the travel mode: a train costs an average of €61, and a flight costs an average of €136.

Distance: 377 miles (608 km)

Compare bus with

Bus
Most popular
Train
Flight

€68

Average price

€65

Average price

Cheapest

€234

Average price

11h 8m

Average total duration

10h 38m

Onboard

+

30m

Additional time*

11h 42m

Average total duration

11h 12m

Onboard

+

30m

Additional time*

4h 31m

Average total duration

Fastest

1h 31m

Onboard

+

3h 0m

Additional time*

Greyhound

Most popular bus company

Amtrak

Most popular train company

Alaska Airlines

Most popular airline

Direct Options

Direct Options

Direct Options

Live departures

Santa Ana, CA to San Francisco, CA bus times

The table below shows live departures for Santa Ana, CA to San Francisco, CA buses for today, Thursday, November 27. You can also manually refresh the results below to see updated bus journeys.

Last updated at 12:21 PM
ProviderDepartsDurationArrivesTransfers
Tickets
meinfernbus_flixbus4:15 PM Santa Ana, CA
10h50
3:05 AM San Francisco, CA0 transfersDirect

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Santa Ana, CA to San Francisco, CA by train, bus, or flight

Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Fri
Nov 28
Sat
Nov 29
Sun
Nov 30
Mon
Dec 01
Tue
Dec 02
Wed
Dec 03
Thu
Dec 04

Journey information

Overview: Bus from Santa Ana, CA to San Francisco, CA

USAUSA
USAUSA
Icon of bus

Buses from Santa Ana, CA to San Francisco, CA run on average 14 times per day, taking around 10h 38m. Cheap bus tickets for this journey start at $67 (€55) if you book in advance.

There are 1 buses per day. The earliest bus runs at 00:05, the last at 23:45. The fastest bus covers the 377 miles (608 km) distance in 10h 50m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
377 miles (608 km)
Average bus duration
10h 38m
Cheapest ticket price
$67 (€55)
Buses per day
14
Direct buses
1
Fastest bus
10h 50m
First bus
00:05
Last bus
23:45
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: Greyhound from Santa Ana, CA to San Francisco, CAYou can travel by bus between Santa Ana, CA to San Francisco, CA with Greyhound for as low as $67 (€55). When you search for schedules and tickets, Omio will show you the best journey

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
13h 50m
Cheapest Price
$63 (€51)
Greyhound frequency
1 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.

FAQs: Bus from Santa Ana, CA to San Francisco, CA

Find answers to the most common questions about traveling from Santa Ana, CA to San Francisco, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Francisco, CA, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Santa Ana, CA to San Francisco, CA can start from as little as $52 (€42) when you book in advance. The average bus ticket price for Santa Ana, CA to San Francisco, CA is $96 (€77); however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Santa Ana, CA to San Francisco, CA is 11 h 15 min   to travel the 376 mile (607 km) long route, with around there are 9 buses per day. Journey times can vary on weekends and holidays.
The first bus from Santa Ana, CA to San Francisco, CA leaves at 12: 05AM. Plan your trip with the Journey Planner   from Omio.
The last bus from Santa Ana, CA to San Francisco, CA leaves at 11: 45PM.
Yes, it is possible to travel from Santa Ana, CA to San Francisco, CA without having to change trains with Greyhound. There is 1 direct bus from Santa Ana, CA to San Francisco, CA each day. There may be fewer direct services available on weekends or holidays.
When taking a bus from Santa Ana, CA to San Francisco, CA, you can count on Greyhound for the best way to get you to San Francisco, CA. You can also check all possible bus providers who offer a service from Santa Ana, CA to San Francisco, CA and compare the amenities they offer before buying a bus ticket.
The cheapest month to travel from Santa Ana, CA to San Francisco, CA by bus is December.
It's helpful to compare your options as there are 3 ways to travel to San Francisco, CA from Santa Ana, CA including taking a train, bus or flight.
Yes, the following accessibility options are available when taking the bus from Santa Ana, CA to San Francisco, CA:
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Santa Ana, CA to San Francisco, CA for bus company Greyhound.
Some of the most interesting sights to explore in San Francisco, CA are:
  • Golden Gate Bridge, an iconic suspension bridge offering panoramic views of the San Francisco Bay
  • Alcatraz Island, a historic site featuring the infamous former prison and informative audio tours
  • Fisherman's Wharf, a bustling waterfront area known for seafood, shops, and sea lions
  • Golden Gate Park, a large urban park with gardens, museums, and recreational activities
  • Chinatown, the oldest and one of the largest Chinatowns in North America, offering vibrant culture and cuisine.
The best things to do in San Francisco, CA include:
  • Ride a cable car through the steep streets of San Francisco for a classic city experience
  • Explore the vibrant murals and street art in the Mission District
  • Visit the Exploratorium, an interactive science museum perfect for all ages
  • Take a scenic walk along the Embarcadero, offering views of the Bay Bridge and access to the Ferry Building Marketplace
  • Enjoy a wine tasting tour in nearby Napa Valley, a short drive from the city.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Whether you can cancel your bus ticket from Santa Ana, CA to San Francisco, CA depends on the bus company:
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.

To find the cheapest bus tickets for your trip from Santa Ana, CA to San Francisco, CA, follow these tips:

  • Book in advance: Tickets are often cheaper when booked early.
  • Be flexible with dates and times: Traveling during off-peak hours or on weekdays can help you save money.
  • Use our search filters: Sort results by price to quickly identify the most affordable options.
  • Look for special deals or discounts: Check for promotions or discounts available on our website and app.
  • Start your search now and compare ticket prices to find the best deal!

    Yes, there is food available to purchase on board the bus from Santa Ana, CA to San Francisco, CA.
    Yes, the following luggage options are included when booking a bus ticket from Santa Ana, CA to San Francisco, CA:
    • Greyhound
      • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
    Yes, the following additional luggage options are available when booking a bus ticket from Santa Ana, CA to San Francisco, CA:
    • Greyhound
      • $15 per additional bag.
    Unfortunately, pets are not allowed on the bus from Santa Ana, CA to San Francisco, CA.
    You can reserve your seat on the bus from Santa Ana, CA to San Francisco, CA with the following bus company: Greyhound
    Yes, there are USB plugs on board the bus from Santa Ana, CA to San Francisco, CA with the following bus company: Greyhound.
    Yes, there is Wifi on board the bus from Santa Ana, CA to San Francisco, CA with the following bus company: Greyhound.

    popular bus stations

    Popular bus stations from Santa Ana, CA to San Francisco, CA

    Santa Ana
    San Francisco
    The major bus station for departures in Santa Ana is Santa Ana, E Santa Ana Blvd (Train Station). Find all the information you need to know about services, amenities and connections at Santa Ana, E Santa Ana Blvd (Train Station) for your trip from Santa Ana to San Francisco.
    Santa Ana, E Santa Ana Blvd (Train Station)
    information

    Most popular buses to and from San Francisco, CA and Santa Ana, CA

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