The cheapest and fastest buses from Santa Ana, CA to San Diego, CA
Cheapest price
$27
Average price
$44
Fastest journey
1 h 45 m
Average duration
1 h 52 m
Buses per day
8
Distance
132 km
The best way to find a cheap bus ticket from Santa Ana, CA to San Diego, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Santa Ana, CA to San Diego, CA will cost around $44 if you buy it on the day, but the cheapest tickets can be found for only $27.
Of the 8 buses that leave Santa Ana, CA for San Diego, CA on Thu, Nov 27, 8 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Nov 27 the direct buses cover the 132 km distance in an average of 1 h 52 m but if you time it right, some buses will get you there in just 1 h 45 m .
On Thu, Nov 27 the slowest buses will take 2 h 15 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus
FlixBus
FlixBus
FlixBus
FlixBus

FlixBus
FlixBusTravel Information
Compare train and bus for Santa Ana, CA to San Diego, CA
Omio recommends booking the train as it is the most popular option from Santa Ana, CA to San Diego, CA among Omio's users. If you are prioritising price take the bus with prices starting from €15. For those with little time consider booking a bus which can get you there in 1h 48m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.0 - 0.1kg. The ticket price range depends on the travel mode: a bus costs an average of €15, and a train costs an average of €26.
Distance: 82 miles (132 km)
Compare bus with
| Bus | Most popular Train |
|---|---|
€22 Average price Cheapest | €27 Average price |
2h 18m Average total duration Fastest 1h 48m Onboard + 30m Additional time* | 2h 24m Average total duration 1h 54m Onboard + 30m Additional time* |
0.1 - 0.3kg CO2 emissions | 0.0 - 0.1kg CO2 emissions Lowest |
![]() Most popular bus company | ![]() Most popular train company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Santa Ana, CA to San Diego, CA Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 10:00AM | Arrival Time 11:45AM | Duration 1h45 | Departure days Wed, Thu, Sat, Sun | Cheapest price $40 |
Operator FlixBus | Departure Time 02:35PM | Arrival Time 04:25PM | Duration 1h50 | Departure days Wed, Thu, Sat, Sun | Cheapest price $24 |
Operator FlixBus | Departure Time 08:30PM | Arrival Time 10:15PM | Duration 1h45 | Departure days Wed, Thu, Sat, Sun | Cheapest price $24 |
Operator Greyhound | Departure Time 10:05PM | Arrival Time 11:50PM | Duration 1h45 | Departure days Wed, Thu, Sat, Sun | Cheapest price $40 |
Live departures
Santa Ana, CA to San Diego, CA bus times
The table below shows live departures for Santa Ana, CA to San Diego, CA buses for today, Wednesday, November 26. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 6:00 PM Santa Ana, E Santa Ana Blvd (Train Station) | 1h45 | 7:45 PM San Diego, Congress Street (Old Town Park), CA | 0 transfersDirect | |
![]() | 6:00 PM Santa Ana, E Santa Ana Blvd (Train Station) | 2h20 | 8:20 PM San Diego, San Ysidro Transit Center | 0 transfersDirect | |
FlixBus | 10:35 PM Santa Ana, E Santa Ana Blvd (Train Station) | 2h35 | 1:10 AM San Diego, San Ysidro Transit Center | 0 transfersDirect | |
FlixBus | 10:35 PM Santa Ana, E Santa Ana Blvd (Train Station) | 1h50 | 12:25 AM San Diego, Congress Street (Old Town Park), CA | 0 transfersDirect | |
| Thursday, November 27 | |||||
FlixBus | 4:30 AM Santa Ana, E Santa Ana Blvd (Train Station) | 2h15 | 6:45 AM San Diego, San Ysidro Transit Center | 0 transfersDirect | |
FlixBus | 4:30 AM Santa Ana, E Santa Ana Blvd (Train Station) | 1h45 | 6:15 AM San Diego, West Harbor Drive (The Headquarters at Seaport District), CA | 0 transfersDirect | |
![]() | 6:05 AM Santa Ana, E Santa Ana Blvd (Train Station) | 2h20 | 8:25 AM San Diego, San Ysidro Transit Center | 0 transfersDirect | |
![]() | 6:05 AM Santa Ana, E Santa Ana Blvd (Train Station) | 1h45 | 7:50 AM San Diego, Congress Street (Old Town Park), CA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Santa Ana, CA to San Diego, CA by train or bus
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Nov 27
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Nov 30
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Dec 03
Journey information
Overview: Bus from Santa Ana, CA to San Diego, CA
Buses from Santa Ana, CA to San Diego, CA run on average 14 times per day, taking around 1h 48m. Cheap bus tickets for this journey start at $19 (€15) if you book in advance.
There are 13 buses per day. The earliest bus runs at 00:05, the last at 23:35. The fastest bus covers the 82 miles (132 km) distance in 1h 45m.
Distance 82 miles (132 km) |
Average bus duration 1h 48m |
Cheapest ticket price $19 (€15) |
Buses per day 14 |
Direct buses 13 |
Fastest bus 1h 45m |
First bus 00:05 |
Last bus 23:35 |
Bus providers: Greyhound, FlixBus, Infobus from Santa Ana, CA to San Diego, CAYou can travel by bus between Santa Ana, CA to San Diego, CA with Greyhound, FlixBus, Infobus for as low as $19 (€15). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Infobus
Greyhound
FAQs: Bus from Santa Ana, CA to San Diego, CA
Find answers to the most common questions about traveling from Santa Ana, CA to San Diego, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Diego, CA, this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Infobus
- Assistance
- Priority seating
- Transport for wheelchairs and mobility aids.
- Balboa Park, a sprawling urban park with museums, gardens, and the San Diego Zoo
- USS Midway Museum, a historic naval aircraft carrier museum offering interactive exhibits and tours
- La Jolla Cove, a picturesque coastal area known for its stunning views and marine life
- Gaslamp Quarter, a lively historic district with Victorian architecture, dining, and entertainment options
- Coronado Beach, a beautiful sandy beach known for its gentle waves and iconic hotel.
- Explore the vibrant art scene at the Museum of Contemporary Art San Diego
- Enjoy a harbor cruise for stunning views of the skyline and naval ships
- Hike the scenic trails at Torrey Pines State Natural Reserve
- Visit the Birch Aquarium to learn about marine life and ocean conservation
- Experience the thrill of a whale watching tour off the coast.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Infobus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Cancellations within 24 hours may incur a fee.
To find the cheapest bus tickets for your trip from Santa Ana, CA to San Diego, CA, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Infobus
- One carry-on bag up to 5kg (40x20x25) and one checked bag up to 20kg (50x30x80).
- FlixBus
- Additional luggage can be purchased for a fee.
- Greyhound
- $15 per additional bag.
- Infobus
- 10€ per additional bag.
- FlixBus
- Small pets in carriers allowed
- Guide dogs travel for free.
- Infobus
- Small pets allowed in carriers
- Larger pets may require a separate ticket.
popular bus stations
Popular bus stations from Santa Ana, CA to San Diego, CA
Most popular bus connections from Santa Ana, CA
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