- Must visit
Museo Nazionale del Paleolitico di Isernia
Major Paleolithic museum beside the renowned prehistoric site. Essential for understanding early human settlement in Europe.
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The cheapest and fastest buses from Rome to Isernia
Showing times, prices and bookable tickets for Nov 03
- Cheapest price on Nov 03
- $15
- Average ticket price on Nov 03
- $16
- Fastest journey on Nov 03
- 2 h 25 m
- Average journey duration on Nov 03
- 2 h 28 m
- Buses on Nov 03
- 2
- Distance
- 149 km
Cheap tickets
The best way to find a cheap bus ticket from Rome to Isernia is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Rome to Isernia will cost around $16 if you buy it on the day, but the cheapest tickets can be found for only $15.
Fast buses
On Tue, Nov 03, we found 2 buses from Rome to Isernia, including 2 direct services.
On Tue, Nov 03 the direct buses cover the 149 km distance in an average of 2 h 28 m but if you time it right, some buses will get you there in just 2 h 25 m .
On Tue, Nov 03 the slowest buses will take 2 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
0584:30 PM 2h30 Roma, Autostazione Tiburtina 7:00 PM Isernia, Piazza della Repubblica (F. Martino bus station) $15 1 One-way 0 transfers
FlixBus2:50 PM 2h25 Roma, Autostazione Tiburtina 5:15 PM Isernia, Piazza della Repubblica (F. Martino bus station) $18 1 One-way 0 transfers
- FlixBus
2:50 PM 2h25 Roma, Autostazione Tiburtina 5:15 PM Isernia, Piazza della Repubblica (F. Martino bus station) $18 1 One-way 0 transfers - 058
4:30 PM 2h30 Roma, Autostazione Tiburtina 7:00 PM Isernia, Piazza della Repubblica (F. Martino bus station) $15 1 One-way 0 transfers
Journey information
Overview: Bus from Rome to Isernia
ItalyItaly
Buses from Rome to Isernia run on average 2 times per day, taking around 2h 33m. Cheap bus tickets for this journey start at $6 if you book in advance.
There are 2 buses per day. The earliest bus runs at 02:45, the last at 23:56. The fastest bus covers the 92 miles (149 km) distance in 2h 10m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Plan this route
Journey facts
- Distance92 miles (149 km)
- Average bus duration2h 33m
- Cheapest ticket price$6
- Buses per day2
- Direct buses2
- Fastest bus2h 10m
- First bus2:45 AM
- Last bus11:56 PM
- Cheapest MonthMar
- Cheapest DaySat
- High SeasonJul - Sep
- Low SeasonJan - Mar
- Busiest DaySat
- Least Busy DayFri
- Best time to book28 days
Understand & plan this route
Explore this journey
Book with confidence
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Frequently asked questions about your Rome to Isernia trip
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Rome to Isernia.
Cheap bus tickets from Rome to Isernia can start from as little as $6 when you book in advance. The average bus ticket price for Rome to Isernia is $19 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The earliest bus from Rome to Isernia leaves at 2:45 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Rome to Isernia leaves at 11:56 PM.
Yes, there are 2 direct buses a day from Rome to Isernia with FlixBus, Marino Autolinee. Schedules can vary on holidays or weekends with fewer direct buses.
Rome to Isernia Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator BlaBlaCar | Departure Time 08:30AM | Arrival Time 10:10AM | Duration 1h40 | Departure days Sat | Cheapest price $12 |
Operator BlaBlaCar | Departure Time 09:00AM | Arrival Time 10:40AM | Duration 1h40 | Departure days Tue | Cheapest price $14 |
Operator BlaBlaCar | Departure Time 12:00PM | Arrival Time 01:40PM | Duration 1h40 | Departure days Fri | Cheapest price $12 |
Operator BlaBlaCar | Departure Time 12:50PM | Arrival Time 02:00PM | Duration 1h10 | Departure days Fri | Cheapest price $11 |
Operator BlaBlaCar | Departure Time 02:40PM | Arrival Time 04:20PM | Duration 1h40 | Departure days Fri | Cheapest price $11 |
Operator FlixBus | Departure Time 02:50PM | Arrival Time 05:15PM | Duration 2h25 | Departure days Tue, Wed, Thu, Fri, Sat, Sun | Cheapest price $13 |
Operator BlaBlaCar | Departure Time 03:00PM | Arrival Time 04:30PM | Duration 1h30 | Departure days Tue | Cheapest price $15 |
Operator BlaBlaCar | Departure Time 04:00PM | Arrival Time 05:30PM | Duration 1h30 | Departure days Sat | Cheapest price $14 |
Operator Marino Autolinee | Departure Time 04:30PM | Arrival Time 07:00PM | Duration 2h30 | Departure days Everyday | Cheapest price $6 |
Operator BlaBlaCar | Departure Time 04:50PM | Arrival Time 05:50PM | Duration 1h00 | Departure days Sat | Cheapest price $14 |
Operator BlaBlaCar | Departure Time 05:00PM | Arrival Time 06:10PM | Duration 1h10 | Departure days Wed | Cheapest price $12 |
Operator BlaBlaCar | Departure Time 05:30PM | Arrival Time 07:00PM | Duration 1h30 | Departure days Tue, Fri | Cheapest price $12 |
Operator BlaBlaCar | Departure Time 05:40PM | Arrival Time 07:30PM | Duration 1h50 | Departure days Sun | Cheapest price $13 |
Operator BlaBlaCar | Departure Time 06:00PM | Arrival Time 07:20PM | Duration 1h20 | Departure days Mon | Cheapest price $14 |
Operator BlaBlaCar | Departure Time 06:20PM | Arrival Time 07:50PM | Duration 1h30 | Departure days Mon | Cheapest price $17 |
Operator BlaBlaCar | Departure Time 06:30PM | Arrival Time 08:00PM | Duration 1h30 | Departure days Fri | Cheapest price $12 |
Operator BlaBlaCar | Departure Time 07:00PM | Arrival Time 09:20PM | Duration 2h20 | Departure days Sun | Cheapest price $23 |
Operator BlaBlaCar | Departure Time 08:20PM | Arrival Time 09:30PM | Duration 1h10 | Departure days Sat | Cheapest price $15 |
Operator BlaBlaCar | Departure Time 08:30PM | Arrival Time 09:50PM | Duration 1h20 | Departure days Tue | Cheapest price $14 |
Live departures
Rome to Isernia bus times
The table below shows live departures for Rome to Isernia buses for tomorrow, Tuesday, November 3. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| FlixBus | 2:50 PM Roma, Autostazione Tiburtina | 2h25 | 5:15 PM Isernia, Piazza della Repubblica (F. Martino bus station) | 0 transfersDirect | |
| 058 | 4:30 PM Roma, Autostazione Tiburtina | 2h30 | 7:00 PM Isernia, Piazza della Repubblica (F. Martino bus station) | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Why should you book Rome to Isernia buses with Omio?
FlixBus as well as Marino Autolinee offer buses services from Rome to Isernia.
Omio is an official ticket reseller for all your travel options from Rome to Isernia.
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Marino Autolinee to find the best option for your trip from Rome to Isernia.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train and bus to ensure you get the best deal for traveling from Rome to Isernia.
Why book with Omio over Wanderu, Trainline or Checkmybus?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Marino Autolinee to find the best option for your trip from Rome to Isernia.
- Multiple modes of transport: Omio allows you to compare travel options including train and bus to find the ideal travel option from Rome to Isernia.
Bus companies
Bus companies from Rome to Isernia
Buses from Rome to Isernia with FlixBus and Marino Autolinee. Overnight buses available on this route with FlixBus. Use the details below to compare onboard facilities.
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
2h 10m
Cheapest FlixBus Price
$11
FlixBus frequency
1 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Marino Autolinee
About
MarinoBus is an Italian bus company with more than 200 destinations and 6,000 connections across Italy and Europe. Originally focused on Basilicata and Apulia, its network has expanded to cover the rest of Italy as well as Switzerland, France, Germany, and Luxembourg. All MarinoBus coaches are equipped with spacious reclining seats, air conditioning, onboard restrooms, WiFi, minibars, and color TVs. For your next trip, you can book the standard ticket, which includes one piece of hand luggage and up to two checked bags per passenger
Luggage & cancellation policy
Average Marino Autolinee Duration
2h 30m
Cheapest Marino Autolinee Price
$6
Marino Autolinee frequency
1 a day
Luggage included
One carry-on bag up to 10kg (55x40x20 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
10€ per additional bag up to 20 kg.
Cancellation Policy
You can cancel your ticket up to 24 hours before departure for a full refund. Cancellations within 24 hours incur a 50% fee.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Accessible restrooms.
Bikes
Bikes are allowed.
Pets
Small pets allowed in carriers; larger pets must be leashed and muzzled.
Companies, tickets, and onboard amenities between Rome and Isernia
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
When taking a bus from Rome to Isernia, you can count on FlixBus, Marino Autolinee for the best way to get you to Isernia. You can also check all possible bus companies who offer a service between Rome and Isernia and compare the amenities they offer before buying a bus ticket.
Yes, the following accessibility options are available when taking the bus from Rome to Isernia:
- Marino Autolinee
- Assistance
- Priority seating
- Accessible restrooms.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Rome to Isernia for bus company FlixBus, Marino Autolinee.
Whether you can cancel your bus ticket from Rome to Isernia depends on the bus companies:
- Marino Autolinee
- You can cancel your ticket up to 24 hours before departure for a full refund. Cancellations within 24 hours incur a 50% fee.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company {providersWithBike}.
Yes, there is food available to purchase on board the bus from Rome to Isernia.
Yes, the following luggage options are included when booking a bus ticket from Rome to Isernia:
- Marino Autolinee
- One carry-on bag up to 10kg (55x40x20 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Rome to Isernia:
- Marino Autolinee
- 10€ per additional bag up to 20 kg.
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Rome to Isernia. The following conditions apply:
- Marino Autolinee
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from Rome to Isernia with the following bus company: FlixBus, Marino Autolinee
Yes, there are USB plugs on board the bus from Rome to Isernia with the following bus company: FlixBus, Marino Autolinee.
Yes, there is Wifi on board the bus from Rome to Isernia with the following bus company: FlixBus, Marino Autolinee.
Complete guide to Isernia
Things to do in Isernia
Discover the best of Isernia — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Isernia trip today.
- Recommended
Museo Archeologico di Santa Maria delle Monache
Archaeological area museum presenting finds from the ancient settlement. A strong companion visit to the cathedral and Roman remains.
- Recommended
Complesso Monumentale di Santa Maria delle Monache
Exhibition venue in a historic setting, often used for local heritage displays. Good for visitors interested in community-focused culture.
- Must visit
Corso Marcelli
Main historic street lined with palaces, churches, and shops. The best walk for absorbing Isernia's old-town atmosphere.
- Must visit
Centro Storico di Isernia
The historic center preserves medieval lanes, arches, and layered architecture. Ideal for slow exploration and local street photography.
- Recommended
Piazza Celestino V
Central square near the cathedral and Fontana Fraterna. A practical starting point for discovering the city's key monuments.
Lasagne Alla Molisana
Fresh pasta sheets layered with rich pork ragù, mozzarella, and caciocavallo. A Sunday and feast-day classic in Molise with deep family tradition.
Cavatelli
Small handmade cavatelli pasta, often served with tomato sauce, pork, or seasonal vegetables. It is one of Molise’s best-known home-style staples.
- Vegetarian
- Vegan
Pampanella E Minestra Di Erbe
Rustic soup of field greens, potatoes, beans, and cornbread or stale bread. A traditional peasant dish from the Isernia area, especially in colder months.
Ristorante Da Lulù
Established restaurant known for Molisan cooking, handmade pasta, and local meats in a refined but welcoming setting.
Osteria Le Antiche Mura
Well-regarded traditional venue serving regional specialties, grilled meats, and classic local dishes in a rustic atmosphere.
Ristorante Pizzeria La Strada
Casual, popular spot for pizza and southern Italian dishes, suited to an easy meal with locals and families.
Euro (€)
Moderate for Italy. Hotels and dining are usually cheaper than Rome or Florence, while local buses and coffee remain low-cost for most travelers.
Average meal costs
- Budget
- €8-12 for fast food or a simple meal.
- Mid-range
- €20-35 per person for a restaurant meal.
- Fine dining
- €50+ per person for upscale dining.
- Coffee
- €1.20-2.50 for espresso or cappuccino.
Tipping culture
Tipping is modest. Service may be included. Round up or leave 5-10% at restaurants for good service; round up taxi fares; small change is enough at cafes.
Plan your visit to Isernia
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Isernia.
Italy uses the euro (EUR) as its currency. Travelers generally find it convenient to use cards for most payments, especially in cities and larger establishments, but carrying some cash is advisable for small shops, markets, and rural areas where card acceptance may be limited.
In Isernia, travelers should be cautious of petty theft, especially in crowded areas and near transportation hubs. It is advisable to stay vigilant with personal belongings and avoid accepting unsolicited offers from strangers. There are no widespread reports of specific scams targeting visitors, but standard travel precautions apply, such as using official taxi services and verifying ticket purchases to ensure safety and avoid fraud.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
FAQs: Bus from Rome to Isernia
Find answers to the most common questions about traveling from Rome to Isernia by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Isernia, this guide helps you travel smarter and with confidence.
It's helpful to compare your options as there are 2 ways to travel between Rome and Isernia including taking a train and bus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
popular bus stations
Popular bus stations from Rome to Isernia
Most Rome to Isernia buses use the Roma, Autostazione Tiburtina to Isernia, Piazza della Repubblica (Autostazione F. Martino) station pair. Use this guide to compare Rome and Isernia bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Rome
Arrival bus stations in Isernia
Which Rome station do buses to Isernia leave from?
Buses from Rome to Isernia leave from Roma, Autostazione Tiburtina. The station is 2 miles (4 km) from Rome city centre at Largo Guido Mazzoni, snc, 00162 Roma RM, Italy.
Roma, Autostazione TiburtinaLargo Guido Mazzoni, snc, 00162 Roma RM, Italy
City-centre transport
Getting to Roma, Autostazione Tiburtina from Rome city centre
Roma, Autostazione Tiburtina is 4 km from Rome city centre. Public transport options include:
Bus490, 495 · 16m · $3 · every ~22 min
SubwayMeb · 7m · $3 · every ~15 min
Roma, Autostazione Tiburtina bus station facilities and services
Roma, Autostazione Tiburtina has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Cafes and vending machines available.
Wi-Fi and ATMs
Wi-Fi is available at Roma, Autostazione Tiburtina. ATMs are aTM available near ticket office.
Tickets and information
Ticket office support is available at Roma, Autostazione Tiburtina.
Parking, taxis and toilets
Available at Roma, Autostazione Tiburtina: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Roma, Autostazione Tiburtina: Wheelchair accessible entrances and facilities.
Which Isernia station do buses from Rome arrive at?
Buses from Rome to Isernia arrive at Isernia, Piazza della Repubblica (Autostazione F. Martino). Isernia, Piazza della Repubblica (Autostazione F. Martino) is from Isernia city centre.
Isernia, Piazza della Repubblica (Autostazione F. Martino)Isernia Piazza della Repubblica, 86170 Isernia IS, Italy
City-centre transport
Getting to Isernia, Piazza della Repubblica (Autostazione F. Martino) from Isernia city centre
TRUE
Isernia, Piazza della Repubblica (Autostazione F. Martino) bus station facilities and services
Isernia, Piazza della Repubblica (Autostazione F. Martino) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Nearby cafés and fast food outlets.
Wi-Fi and ATMs
Wi-Fi is available at Isernia, Piazza della Repubblica (Autostazione F. Martino). ATMs are aTM located near the entrance.
Tickets and information
Ticket office support is available at Isernia, Piazza della Repubblica (Autostazione F. Martino).
Parking, taxis and toilets
Available at Isernia, Piazza della Repubblica (Autostazione F. Martino): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Isernia, Piazza della Repubblica (Autostazione F. Martino): Wheelchair accessible facility.
Bus stations for Rome to Isernia
Check bus stations information for Rome and Isernia, including where buses depart and arrive on this route.
Passengers board the bus most frequently from Roma, Autostazione Tiburtina, which is located around 2 miles (4 km) away from the city centre, and they get off the bus at Isernia, Piazza della Repubblica (Autostazione F. Martino), located 0 away from the city centre.
Most popular buses to and from Isernia and Rome
Most popular bus connections to Isernia
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