The cheapest and fastest buses from Rome to Isernia
Cheapest price
$11
Average price
$13
Fastest journey
1 h 10 m
Average duration
1 h 36 m
Buses per day
6
Distance
149 km
The best way to find a cheap bus ticket from Rome to Isernia is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Rome to Isernia will cost around $13 if you buy it on the day, but the cheapest tickets can be found for only $11.
Of the 6 buses that leave Rome for Isernia on Sun, Mar 22, 6 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Mar 22 the direct buses cover the 149 km distance in an average of 1 h 36 m but if you time it right, some buses will get you there in just 1 h 10 m .
On Sun, Mar 22 the slowest buses will take 2 h and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.










Travel Information
Compare bus and train for Rome to Isernia
Omio recommends booking the train as it is the most popular option from Rome to Isernia among Omio's users. If you are prioritising price take the train with prices starting from $17. For those with little time consider booking a bus which can get you there in 2h 14m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.0 - 0.1kg. The ticket price range depends on the travel mode: a train costs an average of $17, and a bus costs an average of $10.
Distance: 92 miles (149 km)
Compare bus with
| Bus | Most popular Train |
|---|---|
$21 Average price | $18 Average price Cheapest |
2h 44m Average total duration Fastest 2h 14m Onboard + 30m Additional time* | 3h 40m Average total duration 3h 10m Onboard + 30m Additional time* |
0.1 - 0.4kg CO2 emissions | 0.0 - 0.1kg CO2 emissions Lowest |
![]() Most popular bus company | ![]() Most popular train company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Rome to Isernia Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator BlaBlaCar | Departure Time 06:00AM | Arrival Time 08:00AM | Duration 2h00 | Departure days Sun | Cheapest price $14 |
Operator BlaBlaCar | Departure Time 08:00AM | Arrival Time 09:40AM | Duration 1h40 | Departure days Mon, Sun | Cheapest price $11 |
Operator BlaBlaCar | Departure Time 09:00AM | Arrival Time 10:50AM | Duration 1h50 | Departure days Sat | Cheapest price $11 |
Operator BlaBlaCar | Departure Time 10:00AM | Arrival Time 11:30AM | Duration 1h30 | Departure days Mon | Cheapest price $11 |
Operator BlaBlaCar | Departure Time 10:20AM | Arrival Time 12:10PM | Duration 1h50 | Departure days Mon | Cheapest price $16 |
Operator BlaBlaCar | Departure Time 10:30AM | Arrival Time 12:20PM | Duration 1h50 | Departure days Sat | Cheapest price $12 |
Operator BlaBlaCar | Departure Time 11:00AM | Arrival Time 12:20PM | Duration 1h20 | Departure days Sat | Cheapest price $9 |
Operator BlaBlaCar | Departure Time 02:00PM | Arrival Time 03:30PM | Duration 1h30 | Departure days Mon, Sun | Cheapest price $11 |
Operator FlixBus | Departure Time 02:50PM | Arrival Time 05:00PM | Duration 2h10 | Departure days Mon, Sat, Sun | Cheapest price $15 |
Operator BlaBlaCar | Departure Time 02:50PM | Arrival Time 04:20PM | Duration 1h30 | Departure days Sat | Cheapest price $11 |
Operator BlaBlaCar | Departure Time 03:30PM | Arrival Time 04:40PM | Duration 1h10 | Departure days Mon | Cheapest price $13 |
Operator BlaBlaCar | Departure Time 04:00PM | Arrival Time 05:30PM | Duration 1h30 | Departure days Sun | Cheapest price $12 |
Operator BlaBlaCar | Departure Time 05:30PM | Arrival Time 07:00PM | Duration 1h30 | Departure days Sat | Cheapest price $11 |
Operator BlaBlaCar | Departure Time 07:50PM | Arrival Time 09:40PM | Duration 1h50 | Departure days Sun | Cheapest price $12 |
Live departures
Rome to Isernia bus times
The table below shows live departures for Rome to Isernia buses for tomorrow, Saturday, March 21. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus | 1:50 PM Roma, Autostazione Tiburtina | 2h10 | 4:00 PM Isernia, Piazza della Repubblica (F. Martino bus station) | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Rome to Isernia by bus or train
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 22
Mar 23
Mar 24
Mar 25
Mar 26
Mar 27
Mar 28
Why should you book Rome to Isernia buses with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of ATM Azienda di Trasporti Molisana S.p.A. to find the best option for your trip from Rome to Isernia.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus and train to ensure you get the best deal for traveling from Rome to Isernia.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including bus and train to find the ideal travel option from Rome to Isernia.
Journey information
Overview: Bus from Rome to Isernia
Buses from Rome to Isernia run on average 10 times per day, taking around 2h 14m. Cheap bus tickets for this journey start at $10 (€8) if you book in advance.
There are 6 buses per day. The earliest bus runs at 02:45, the last at 23:56. The fastest bus covers the 92 miles (149 km) distance in 2h 10m.
Distance 92 miles (149 km) |
Average bus duration 2h 14m |
Cheapest ticket price $10 (€8) |
Buses per day 10 |
Direct buses 6 |
Fastest bus 2h 10m |
First bus 02:45 |
Last bus 23:56 |
Bus providers: FlixBus, BlaBlaCar, ATM Azienda di Trasporti Molisana S.p.A. from Rome to IserniaYou can travel by bus between Rome to Isernia with FlixBus, BlaBlaCar, ATM Azienda di Trasporti Molisana S.p.A. for as low as $10 (€8). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
BlaBlaCar
ATM Azienda di Trasporti Molisana S.p.A.
FAQs: Bus from Rome to Isernia
Find answers to the most common questions about traveling from Rome to Isernia by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Isernia, this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Rome to Isernia
More options for your journey from Rome to Isernia
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