Are there accessibility options when taking a bus from Rome to Isernia?

Yes, the following accessibility options are available when taking the bus from Rome to Isernia: FlixBus Assistance Priority boarding Wheelchair-accessible buses.

Is luggage included in the bus ticket price from Rome to Isernia?

Yes, the following luggage options are included when booking a bus ticket from Rome to Isernia: FlixBus One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).

Can I bring my pet on board the bus from Rome to Isernia?

Yes, you can bring your pet on the bus from Rome to Isernia. The following conditions apply: FlixBus Small pets in carriers allowed guide dogs travel for free.

ROME to ISERNIA bus from $10 (€8) with FlixBus

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The cheapest and fastest buses from Rome to Isernia

Showing times and prices for Jun 21

Cheapest price

Average price

$12

Fastest journey

2 h 25 m

Average duration

2 h 28 m

Buses per day

Distance

149 km

Cheap tickets

The best way to find a cheap bus ticket from Rome to Isernia is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Rome to Isernia will cost around $12 if you buy it on the day, but the cheapest tickets can be found for only $6.

Fast buses

Of the 2 buses that leave Rome for Isernia on Sun, Jun 21, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.

On Sun, Jun 21 the direct buses cover the 149 km distance in an average of 2 h 28 m but if you time it right, some buses will get you there in just 2 h 25 m .

On Sun, Jun 21 the slowest buses will take 2 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

058
4:30 PM2h30
Roma, Autostazione Tiburtina
7:00 PMIsernia, Piazza della Repubblica (F. Martino bus station)
$61One-way
0 transfers
FlixBus
2:50 PM2h25
Roma, Autostazione Tiburtina
5:15 PMIsernia, Piazza della Repubblica (F. Martino bus station)
$181One-way
0 transfers

Travel Information

Compare train and bus for Rome to Isernia

Omio recommends booking the train as it is the most popular option from Rome to Isernia among Omio's users. If you are prioritising price take the train with prices starting from $17. For those with little time consider booking a bus which can get you there in 2h 13m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.0 - 0.1kg. The ticket price range depends on the travel mode: a train costs an average of $17, and a bus costs an average of $10.

Distance: 92 miles (149 km)

Compare bus with

Bus	Most popular Train	Driving
$17 Average price	$17 Average price Cheapest	$49 Average price (fuel + tolls)
2h 43m Average total duration Fastest 2h 13m Onboard + 30m Additional time*	3h 40m Average total duration 3h 10m Onboard + 30m Additional time*	2h 12m Average total duration (door-to-door)
0.1 - 0.4kg CO2 emissions	0.0 - 0.1kg CO2 emissions Lowest	- CO2 emissions
Most popular bus company	Most popular train company	Your own car or car rental
Direct Options	Direct Options	Direct Options

Additional time: Average total travel duration to departure point, security checks and transfers.

The cheapest way to travel from Rome to Isernia is a train with an average price of $17 (€14).

This is compared to other travel options from Rome to Isernia:

A train is $0.10 (€0.08) less than a bus for this route with tickets for a bus from Rome to Isernia costing on average $17 (€14).

The fastest way to travel from Rome to Isernia is by bus with an average journey time of 2h 13m.

Other travel options to Isernia take longer:

Train takes on average 3h 10m.

It's helpful to compare your options as there are 2 ways to travel between Rome and Isernia including taking a train and bus.

We recommend using the train as it is the most popular way to get from Rome to Isernia among Omio's users.

Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.

Tickets start at around $17 (€14) compared to roughly $49 (€40) in fuel and tolls — a saving of about $32 (€26). The journey takes 2h 13m versus 2h 12m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.

Direct services are operated by FlixBus, BlaBlaCar, ATM Azienda di Trasporti Molisana S.p.A..

Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.

Rome to Isernia Bus Timetables

Operator	Departure Time	Arrival Time	Duration	Departure days	Cheapest price
Operator FlixBus	Departure Time 05:45AM	Arrival Time 11:34AM	Duration 5h49	Departure days Sat	Cheapest price $41
Operator BlaBlaCar	Departure Time 06:00AM	Arrival Time 07:20AM	Duration 1h20	Departure days Mon	Cheapest price $14
Operator BlaBlaCar	Departure Time 07:00AM	Arrival Time 08:20AM	Duration 1h20	Departure days Thu	Cheapest price $15
Operator BlaBlaCar	Departure Time 07:20AM	Arrival Time 08:30AM	Duration 1h10	Departure days Mon	Cheapest price $9
Operator BlaBlaCar	Departure Time 07:40AM	Arrival Time 09:20AM	Duration 1h40	Departure days Sun	Cheapest price $11
Operator BlaBlaCar	Departure Time 08:10AM	Arrival Time 09:20AM	Duration 1h10	Departure days Sun	Cheapest price $12
Operator BlaBlaCar	Departure Time 08:20AM	Arrival Time 09:40AM	Duration 1h20	Departure days Sat	Cheapest price $15
Operator BlaBlaCar	Departure Time 08:40AM	Arrival Time 10:30AM	Duration 1h50	Departure days Fri	Cheapest price $14
Operator FlixBus	Departure Time 09:50AM	Arrival Time 06:14PM	Duration 8h24	Departure days Sat	Cheapest price $82
Operator BlaBlaCar	Departure Time 10:10AM	Arrival Time 11:40AM	Duration 1h30	Departure days Sun	Cheapest price $19
Operator BlaBlaCar	Departure Time 10:40AM	Arrival Time 11:50AM	Duration 1h10	Departure days Sat	Cheapest price $13
Operator BlaBlaCar	Departure Time 12:00PM	Arrival Time 01:40PM	Duration 1h40	Departure days Sun	Cheapest price $9
Operator BlaBlaCar	Departure Time 12:50PM	Arrival Time 03:00PM	Duration 2h10	Departure days Fri	Cheapest price $15
Operator FlixBus	Departure Time 12:50PM	Arrival Time 03:00PM	Duration 2h10	Departure days Tue, Wed	Cheapest price $15
Operator BlaBlaCar	Departure Time 01:00PM	Arrival Time 02:50PM	Duration 1h50	Departure days Fri	Cheapest price $18
Operator BlaBlaCar	Departure Time 01:10PM	Arrival Time 02:20PM	Duration 1h10	Departure days Mon	Cheapest price $12
Operator BlaBlaCar	Departure Time 01:50PM	Arrival Time 03:20PM	Duration 1h30	Departure days Thu	Cheapest price $15
Operator FlixBus	Departure Time 01:50PM	Arrival Time 04:00PM	Duration 2h10	Departure days Tue, Wed	Cheapest price $19
Operator BlaBlaCar	Departure Time 02:20PM	Arrival Time 03:30PM	Duration 1h10	Departure days Fri	Cheapest price $11
Operator BlaBlaCar	Departure Time 02:40PM	Arrival Time 03:50PM	Duration 1h10	Departure days Mon	Cheapest price $9
Operator FlixBus	Departure Time 02:50PM	Arrival Time 05:15PM	Duration 2h25	Departure days Mon, Thu, Fri, Sun	Cheapest price $18
Operator BlaBlaCar	Departure Time 02:50PM	Arrival Time 04:00PM	Duration 1h10	Departure days Fri	Cheapest price $15
Operator BlaBlaCar	Departure Time 03:00PM	Arrival Time 04:10PM	Duration 1h10	Departure days Mon	Cheapest price $12
Operator BlaBlaCar	Departure Time 03:30PM	Arrival Time 05:00PM	Duration 1h30	Departure days Fri	Cheapest price $12
Operator BlaBlaCar	Departure Time 03:40PM	Arrival Time 04:40PM	Duration 1h00	Departure days Fri, Sun	Cheapest price $11
Operator BlaBlaCar	Departure Time 04:00PM	Arrival Time 05:20PM	Duration 1h20	Departure days Fri	Cheapest price $15
Operator BlaBlaCar	Departure Time 04:20PM	Arrival Time 05:50PM	Duration 1h30	Departure days Mon	Cheapest price $11
Operator BlaBlaCar	Departure Time 04:30PM	Arrival Time 05:40PM	Duration 1h10	Departure days Thu, Sun	Cheapest price $11
Operator Marino Autolinee	Departure Time 04:30PM	Arrival Time 07:00PM	Duration 2h30	Departure days Mon, Thu, Fri, Sat, Sun	Cheapest price $6
Operator BlaBlaCar	Departure Time 04:50PM	Arrival Time 06:20PM	Duration 1h30	Departure days Sat	Cheapest price $13
Operator BlaBlaCar	Departure Time 05:00PM	Arrival Time 06:10PM	Duration 1h10	Departure days Mon, Fri	Cheapest price $12
Operator BlaBlaCar	Departure Time 06:10PM	Arrival Time 07:20PM	Duration 1h10	Departure days Thu	Cheapest price $17
Operator BlaBlaCar	Departure Time 06:30PM	Arrival Time 09:00PM	Duration 2h30	Departure days Mon	Cheapest price $12
Operator BlaBlaCar	Departure Time 08:10PM	Arrival Time 09:30PM	Duration 1h20	Departure days Thu	Cheapest price $14
Operator BlaBlaCar	Departure Time 08:20PM	Arrival Time 09:30PM	Duration 1h10	Departure days Sat	Cheapest price $13
Operator BlaBlaCar	Departure Time 09:50PM	Arrival Time 11:00PM	Duration 1h10	Departure days Fri	Cheapest price $9
Operator BlaBlaCar	Departure Time 11:50PM	Arrival Time 01:10AM	Duration 1h20	Departure days Sat	Cheapest price $11

Live departures

Rome to Isernia bus times

The table below shows live departures for Rome to Isernia buses for today, Saturday, June 20. You can also manually refresh the results below to see updated bus journeys.

Last updated at

Provider	Departs	Duration	Arrives	Transfers
FlixBus · FlixBus	5:45 AM Roma, Autostazione Tiburtina	5h49	11:34 AM Isernia, Piazza della Repubblica (F. Martino bus station)	1 transfer
FlixBus · FlixBus	9:50 AM Roma, Autostazione Tiburtina	8h24	6:14 PM Isernia, Piazza della Repubblica (F. Martino bus station)	1 transfer
058	4:30 PM Roma, Autostazione Tiburtina	2h30	7:00 PM Isernia, Piazza della Repubblica (F. Martino bus station)	0 transfersDirect
This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Rome to Isernia by train or bus

Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Sun
Jun 21

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Jun 25

Fri
Jun 26

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Jun 27

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Jun 28

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Why should you book Rome to Isernia buses with Omio?

FlixBus as well as ATM Azienda di Trasporti Molisana S.p.A. offer buses services from Rome to Isernia.

Omio is an official ticket reseller for all your travel options from Rome to Isernia.

Why book with Omio vs FlixBus?

Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of ATM Azienda di Trasporti Molisana S.p.A. to find the best option for your trip from Rome to Isernia.
Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train and bus to ensure you get the best deal for traveling from Rome to Isernia.

Why book with Omio over Wanderu or Trainline?

Multiple modes of transport: Omio allows you to compare travel options including train and bus to find the ideal travel option from Rome to Isernia.

Journey information

Overview: Bus from Rome to Isernia

Italy

Buses from Rome to Isernia run on average 10 times per day, taking around 2h 13m. Cheap bus tickets for this journey start at $10 (€8) if you book in advance.

There are 6 buses per day. The earliest bus runs at 02:45, the last at 23:56. The fastest bus covers the 92 miles (149 km) distance in 2h 10m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.

Price information

Distance

92 miles (149 km)

Average bus duration

2h 13m

Cheapest ticket price

$10 (€8)

Buses per day

Direct buses

Fastest bus

2h 10m

First bus

2:45 AM

Last bus

11:56 PM

Cheapest Month

Mar

Cheapest Day

Sat

High Season

Jul - Sep

Low Season

Jan - Mar

Busiest Day

Sun

Least Busy Day

Fri

Best time to book

4 days

Price information

Bus providers: FlixBus, BlaBlaCar, ATM Azienda di Trasporti Molisana S.p.A. from Rome to IserniaYou can travel by bus between Rome to Isernia with FlixBus, BlaBlaCar, ATM Azienda di Trasporti Molisana S.p.A. for as low as $10 (€8). When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About

FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.

Luggage & cancellation policy

Average Duration

2h 10m

Cheapest Price

$10 (€8)

FlixBus frequency

1 a day

Luggage included

One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).

Additional luggage

Additional luggage can be purchased for a fee.

Cancellation Policy

You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.

Amenities on board the bus

Wifi

Food sold onboard

Seat reservation

Toilets

USB plugs

Accessibility

Assistance; Priority boarding; Wheelchair-accessible buses.

Bikes

Bikes are allowed for a fee; must be booked.

Pets

Small pets in carriers allowed; guide dogs travel for free.

Learn more about FlixBus

BlaBlaCar

About

BlaBlaCar is a French online marketplace for carpooling, connecting drivers with empty seats and passengers traveling to the same destination to share costs. Founded in 2006, it operates in Europe and Latin America, boasting 26 million active members. The platform also includes BlaBlaCar Bus, an intercity bus service. BlaBlaCar's name comes from its rating system for drivers' chattiness: "Bla" for quiet, "BlaBla" for talkative, and "BlaBlaBla" for very chatty. The company aims to be the leading marketplace for shared travel, offering affordable and sustainable solutions by combining carpooling with bus journeys.

Luggage & cancellation policy

BlaBlaCar frequency

5 a day

ATM Azienda di Trasporti Molisana S.p.A.

Luggage & cancellation policy

Average Duration

2h 10m

Cheapest Price

$12 (€10)

ATM Azienda di Trasporti Molisana S.p.A. frequency

2 a day

FAQs: Bus from Rome to Isernia

Find answers to the most common questions about traveling from Rome to Isernia by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Isernia, this guide helps you travel smarter and with confidence.

Cheap bus tickets from Rome to Isernia can start from as little as $10 (€8) when you book in advance. The average bus ticket price for Rome to Isernia is $17 (€14) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.

The average journey time by bus from Rome to Isernia is 2h 10m to travel the 92 miles (149 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.

The earliest bus from Rome to Isernia leaves at 2:45 AM. Plan your trip with the Journey Planner from Omio.

The latest bus from Rome to Isernia leaves at 11:56 PM.

Yes, there are 6 direct buses a day from Rome to Isernia with FlixBus, BlaBlaCar, ATM Azienda di Trasporti Molisana S.p.A.. Schedules can vary on holidays or weekends with fewer direct buses.

When taking a bus from Rome to Isernia, you can count on FlixBus, BlaBlaCar, ATM Azienda di Trasporti Molisana S.p.A. for the best way to get you to Isernia. You can also check all possible bus companies who offer a service between Rome and Isernia and compare the amenities they offer before buying a bus ticket.

A trip to Isernia from Rome is worth doing but not as a day trip with a journey time of 2h 10m each way. Check with Omio app the best way to travel.

The cheapest month for a bus from Rome to Isernia is March.

It's helpful to compare your options as there are 2 ways to travel between Rome and Isernia including taking a train and bus.

Yes, the following accessibility options are available when taking the bus from Rome to Isernia:

FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.

Yes, there are bathrooms on board the bus from Rome to Isernia for bus company FlixBus.

Whether you can cancel your bus ticket from Rome to Isernia depends on the bus companies:

FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.

Yes, bikes are allowed on board the bus with bus company FlixBus.

Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.

Yes, there is food available to purchase on board the bus from Rome to Isernia.

Yes, the following luggage options are included when booking a bus ticket from Rome to Isernia:

FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).

Yes, the following additional luggage options are available when booking a bus ticket from Rome to Isernia:

FlixBus
- Additional luggage can be purchased for a fee.

Yes, you can bring your pet on the bus from Rome to Isernia. The following conditions apply:

FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.

You can reserve your seat on the bus from Rome to Isernia with the following bus company: FlixBus

Yes, there are USB plugs on board the bus from Rome to Isernia with the following bus company: FlixBus.

Yes, there is Wifi on board the bus from Rome to Isernia with the following bus company: FlixBus.

Since both Rome and Isernia are in the Schengen Area, a passport is not required for European Union (EU) or Schengen-associated country citizens. A national ID card is sufficient.

We recommend using the train as it is the most popular way to get from Rome to Isernia among Omio's users.

Italy uses the euro (EUR) as its currency. Travelers generally find it convenient to use cards for most payments, especially in cities and larger establishments, but carrying some cash is advisable for small shops, markets, and rural areas where card acceptance may be limited.

In Isernia, travelers should be cautious of petty theft, especially in crowded areas and near transportation hubs. It is advisable to stay vigilant with personal belongings and avoid accepting unsolicited offers from strangers. There are no widespread reports of specific scams targeting visitors, but standard travel precautions apply, such as using official taxi services and verifying ticket purchases to ensure safety and avoid fraud.

Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from Rome to Isernia

Rome

Isernia

The major bus station for departures in Rome is Roma, Autostazione Tiburtina. Find all the information you need to know about services, amenities and connections at Roma, Autostazione Tiburtina for your trip from Rome to Isernia.

Roma, Autostazione Tiburtina

information

Most popular bus connections from Rome

Bus Rome - Roccella Ionica

Bus Rome - Ascoli Piceno

Bus Rome - Lido di Ostia

More options for your journey from Rome to Isernia

Here are some other resources that might have the information you need

Return journeys for buses from Isernia to Rome

Trains from Rome to Isernia

Compare all journeys between Rome and Isernia

Tickets and more information for coaches to Rome

Tickets and more information for coaches to Isernia

Most popular bus connections to Isernia

Bus Naples - Isernia

Bus Campobasso - Isernia

Bus Venafro - Isernia

Bus Cassino - Isernia

Bus Bojano - Isernia

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The cheapest and fastest buses from Rome to Isernia

Travel Information

Compare train and bus for Rome to Isernia

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What is the cheapest way to get from Rome to Isernia?

What is the fastest way from Rome to Isernia?

Is there a bus from Rome to Isernia?

What's the best way to get from Rome to Isernia?

Should I drive or take the bus?

Rome to Isernia Bus Timetables

Live departures

Rome to Isernia bus times

Compare prices and tickets Rome to Isernia by train or bus

Why should you book Rome to Isernia buses with Omio?

Why book with Omio vs FlixBus?

Why book with Omio over Wanderu or Trainline?

Journey information

Overview: Bus from Rome to Isernia

FlixBus

BlaBlaCar

ATM Azienda di Trasporti Molisana S.p.A.

FAQs: Bus from Rome to Isernia

How much does the bus from Rome to Isernia cost?

How long does the bus from Rome to Isernia take?

What’s the earliest bus time from Rome to Isernia?

What’s the latest bus time from Rome to Isernia?

Are there any direct buses from Rome to Isernia?

What bus companies go from Rome to Isernia?

Can I do a day trip to Isernia from Rome?

What is the cheapest month to take a bus from Rome to Isernia?

Is there a bus from Rome to Isernia?

Are there accessibility options when taking a bus from Rome to Isernia?

Are there toilets on board the bus from Rome to Isernia?

Can I cancel my bus ticket from Rome to Isernia?

Can I bring my bike on board the bus from Rome to Isernia?

How can I find the cheapest bus tickets to get from Rome to Isernia?

Is there food available to purchase on board the bus from Rome to Isernia?

Is luggage included in the bus ticket price from Rome to Isernia?

Can I book additional luggage for the bus from Rome to Isernia?

Can I bring my pet on board the bus from Rome to Isernia?

Can I book my seat for the bus from Rome to Isernia?

Are there USB plugs on board the bus from Rome to Isernia?

Is there WiFi on board the bus from Rome to Isernia?

Do I need a passport to travel from Rome to Isernia?

What's the best way to get from Rome to Isernia?

What currency is used in Isernia and is it better to use cash or card?

What are the main safety concerns and scams to watch out for in Isernia?

What are some general packing tips for comfort and security?

popular bus stations

Popular bus stations from Rome to Isernia

Most popular bus connections from Rome

More options for your journey from Rome to Isernia

Most popular buses to and from Isernia and Rome

Most popular bus connections to Isernia

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